Association between rs2431697 T allele on 5q33.3 and systemic lupus erythematosus: case-control study and meta-analysis

Clinical Rheumatology

Volumn 34, Issue 11, 2015, Pages 1893-1902

  Tang, Zhao Ming ^a   Wang, Ping ^a   Chang, Pan Pan ^a   Hasahya, Tony ^a   Xing, Hui ^a   Wang, Jin Ping ^a   Hu, Li Hua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Autoantibody; Autoimmune disease; Genetic predisposition; Single nucleotide polymorphism

Indexed keywords

DOUBLE STRANDED DNA ANTIBODY;

ADOLESCENT; ADULT; AGED; ALLELE; ANTIBODY DETECTION; ARTICLE; ASIAN; CASE CONTROL STUDY; CHILD; CHROMOSOME 5Q; CONTROLLED STUDY; ETHNICITY; EUROPEAN; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HAN CHINESE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS; ASIAN CONTINENTAL ANCESTRY GROUP; CAUCASIAN; CHINA; CHROMOSOME 5; GENETIC PREDISPOSITION; GENETICS; META ANALYSIS; MIDDLE AGED; ODDS RATIO; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHILD; CHINA; CHROMOSOMES, HUMAN, PAIR 5; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 84945443084     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-015-3045-4     Document Type: Article

References (32)

1. Furst DE, Clarke AE, Fernandes AW, Bancroft T, Greth W, Iorga SR (2013) Incidence and prevalence of adult systemic lupus erythematosus in a large US managed-care population. Lupus 22(1):99–105. doi:10.1177/0961203312463110
2. Simard JF, Costenbader KH (2007) What can epidemiology tell us about systemic lupus erythematosus? Int J Clin Pract 61(7):1170–1180. doi:10.1111/j.1742-1241.2007.01434.x
3. Alarcon-Segovia D, Alarcon-Riquelme ME, Cardiel MH, Caeiro F, Massar0do L, Villa AR, Pons-Estel BA (2005) Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort. Arthritis Rheum 52(4):1138–1147. doi:10.1002/art.20999
4. Deapen D, Escalante A, Weinrib L, Horwitz D, Bachman B, Roy‐Burman P, Walker A, Mack TM (1992) A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum 35(3):311–318
5. Cui Y, Sheng Y, Zhang X (2013) Genetic susceptibility to SLE: recent progress from GWAS. J Autoimmun 41:25–33. doi:10.1016/j.jaut.2013.01.008
6. Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, Tsao BP, Vyse TJ, Langefeld CD, Nath SK, Guthridge JM, Cobb BL, Mirel DB, Marion MC, Williams AH, Divers J, Wang W, Frank SG, Namjou B, Gabriel SB, Lee AT, Gregersen PK, Behrens TW, Taylor KE, Fernando M, Zidovetzki R, Gaffney PM, Edberg JC, Rioux JD, Ojwang JO, James JA, Merrill JT, Gilkeson GS, Seldin MF, Yin H, Baechler EC, Li QZ, Wakeland EK, Bruner GR, Kaufman KM, Kelly JA (2008) Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 40(2):204–210. doi:10.1038/ng.81
7. Ramos PS, Criswell LA, Moser KL, Comeau ME, Williams AH, Pajewski NM, Chung SA, Graham RR, Zidovetzki R, Kelly JA, Kaufman KM, Jacob CO, Vyse TJ, Tsao BP, Kimberly RP, Gaffney PM, Alarcon-Riquelme ME, Harley JB, Langefeld CD (2011) A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap. PLoS Genet 7(12):e1002406. doi:10.1371/journal.pgen.1002406
8. Orozco G, Eyre S, Hinks A, Bowes J, Morgan AW, Wilson AG, Wordsworth P, Steer S, Hocking L, Thomson W, Worthington J, Barton A (2011) Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 70(3):463–468. doi:10.1136/ard.2010.137174
9. Chung SA, Taylor KE, Graham RR, Nititham J, Lee AT, Ortmann WA, Jacob CO, Alarcon-Riquelme ME, Tsao BP, Harley JB, Gaffney PM, Moser KL, Slegen PM, Demirci FY, Kamboh MI, Manzi S, Gregersen PK, Langefeld CD, Behrens TW, Criswell LA (2011) Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet 7(3):e1001323. doi:10.1371/journal.pgen.1001323
10. Lee HS, Kim T, Bang SY, Na YJ, Kim I, Kim K, Kim JH, Chung YJ, Shin HD, Kang YM, Shim SC, Suh CH, Park YB, Kim JS, Kang C, Bae SC (2013) Ethnic specificity of lupus-associated loci identified in a genome-wide association study in Korean women. Ann Rheum Dis. doi:10.1136/annrheumdis-2012-202675
11. Luo X, Yang W, Ye DQ, Cui H, Zhang Y, Hirankarn N, Qian X, Tang Y, Lau YL, de Vries N, Tak PP, Tsao BP, Shen N (2011) A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. PLoS Genet 7(6):e1002128. doi:10.1371/journal.pgen.1002128
12. Dupont WD, Plummer WD Jr (1990) Power and sample size calculations. A review and computer program. Control Clin Trials 11(2):116–128
13. Sterne JA, Egger M (2001) Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol 54(10):1046–1055
14. Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315(7109):629–634
15. Han JW, Zheng HF, Cui Y, Sun LD, Ye DQ, Hu Z, Xu JH, Cai ZM, Huang W, Zhao GP, Xie HF, Fang H, Lu QJ, Li XP, Pan YF, Deng DQ, Zeng FQ, Ye ZZ, Zhang XY, Wang QW, Hao F, Ma L, Zuo XB, Zhou FS, Du WH, Cheng YL, Yang JQ, Shen SK, Li J, Sheng YJ, Zuo XX, Zhu WF, Gao F, Zhang PL, Guo Q, Li B, Gao M, Xiao FL, Quan C, Zhang C, Zhang Z, Zhu KJ, Li Y, Hu DY, Lu WS, Huang JL, Liu SX, Li H, Ren YQ, Wang ZX, Yang CJ, Wang PG, Zhou WM, Lv YM, Zhang AP, Zhang SQ, Lin D, Low HQ, Shen M, Zhai ZF, Wang Y, Zhang FY, Yang S, Liu JJ, Zhang XJ (2009) Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet 41(11):1234–1237. doi:10.1038/ng.472
16. Lofgren SE, Frostegard J, Truedsson L, Pons-Estel BA, D’Alfonso S, Witte T, Lauwerys BR, Endreffy E, Kovacs L, Vasconcelos C, Martins da Silva B, Kozyrev SV, Alarcon-Riquelme ME (2012) Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene. Genes Immun 13(3):268–274. doi:10.1038/gene.2011.84
17. Tang Y, Luo X, Cui H, Ni X, Yuan M, Guo Y, Huang X, Zhou H, de Vries N, Tak PP, Chen S, Shen N (2009) MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. Arthritis Rheum 60(4):1065–1075. doi:10.1002/art.24436
18. Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A 103(33):12481–12486. doi:10.1073/pnas.0605298103
19. Miao CG, Yang YY, He X, Huang C, Huang Y, Zhang L, Lv XW, Jin Y, Li J (2013) The emerging role of microRNAs in the pathogenesis of systemic lupus erythematosus. Cell Signal 25: 2013/05/28 edn. doi:10.1016/j.cellsig.2013.05.006
20. Chan EK, Satoh M, Pauley KM (2009) Contrast in aberrant microRNA expression in systemic lupus erythematosus and rheumatoid arthritis: is microRNA-146 all we need? Arthritis Rheum 60(4):912–915. doi:10.1002/art.24421
21. Koutouzov S, Mathian A, Dalloul A (2006) Type-I interferons and systemic lupus erythematosus. Autoimmun Rev 5(8):554–562. doi:10.1016/j.autrev.2006.05.002
22. Pascual V, Farkas L, Banchereau J (2006) Systemic lupus erythematosus: all roads lead to type I interferons. Curr Opin Immunol 18(6):676–682. doi:10.1016/j.coi.2006.09.014
23. Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, Li Y, Kurreeman FA, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos CI, Ardlie KG, Consortium B, Barton A, Bowes J, Brouwer E, Burtt NP, Catanese JJ, Coblyn J, Coenen MJ, Costenbader KH, Criswell LA, Crusius JB, Cui J, de Bakker PI, De Jager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TW, Kastner DL, Ke X, Lee AT, Liu X, Martin P, Morgan AW, Padyukov L, Posthumus MD, Radstake TR, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, van der Helm-van Mil AH, van der Horst-Bruinsma IE, van der Schoot CE, van Riel PL, Weinblatt ME, Wilson AG, Wolbink GJ, Wordsworth BP, Consortium Y, Wijmenga C, Karlson EW, Toes RE, de Vries N, Begovich AB, Worthington J, Siminovitch KA, Gregersen PK, Klareskog L, Plenge RM (2010) Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 42(6):508–514. doi:10.1038/ng.582
24. Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, Harley JB (2003) Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 349(16):1526–1533. doi:10.1056/NEJMoa021933
25. Mok CC, Lau CS (2003) Pathogenesis of systemic lupus erythematosus. J Clin Pathol 56(7):481–490. doi:10.1136/jcp.56.7.481
26. Yuan YJ, Luo XB, Shen N (2010) Current advances in lupus genetic and genomic studies in Asia. Lupus 19(12):1374–1383. doi:10.1177/0961203310376639
27. Yang W, Shen N, Ye DQ, Liu Q, Zhang Y, Qian XX, Hirankarn N, Ying D, Pan HF, Mok CC, Chan TM, Wong RW, Lee KW, Mok MY, Wong SN, Leung AM, Li XP, Avihingsanon Y, Wong CM, Lee TL, Ho MH, Lee PP, Chang YK, Li PH, Li RJ, Zhang L, Wong WH, Ng IO, Lau CS, Sham PC, Lau YL (2010) Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet 6(2):e1000841. doi:10.1371/journal.pgen.1000841
28. Schwartzman-Morris J, Putterman C (2012) Gender differences in the pathogenesis and outcome of lupus and of lupus nephritis. Clin Dev Immunol 2012:604892. doi:10.1155/2012/604892
29. Hughes T, Adler A, Merrill JT, Kelly JA, Kaufman KM, Williams A, Langefeld CD, Gilkeson GS, Sanchez E, Martin J, Boackle SA, Stevens AM, Alarcon GS, Niewold TB, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Criswell LA, Vila LM, Jacob CO, Gaffney PM, Moser KL, Vyse TJ, Alarcon-Riquelme ME, Network B, James JA, Tsao BP, Scofield RH, Harley JB, Richardson BC, Sawalha AH (2012) Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus. Ann Rheum Dis 71(5):694–699. doi:10.1136/annrheumdis-2011-200385
30. Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, Burtt NP, Guiducci C, Parkin M, Gates C, Plenge RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, Graham DC, Wong AK, Vyse TJ, Daly MJ, Altshuler D, Moser KL, Gaffney PM (2008) Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 40: 2009/01/24 edn. doi:10.1038/ng.200
31. Kadota K, Mori M, Yanagimachi M, Miyamae T, Hara T, Kanetaka T, Nozawa T, Kikuchi M, Hara R, Imagawa T, Kaneko T, Yokota S (2013) Analysis of gender differences in genetic risk: association of TNFAIP3 polymorphism with male childhood-onset systemic lupus erythematosus in the Japanese population. PLoS One 8(8):e72551. doi:10.1371/journal.pone.0072551
32. Ji JD, Cha ES, Lee WJ (2014) Association of miR-146a polymorphisms with systemic lupus erythematosus: a meta-analysis. Lupus 23(10):1023–1030. doi:10.1177/0961203314534512