Synergistic actions of blocking angiopoietin-2 and tumor necrosis factor-α in suppressing remodeling of blood vessels and lymphatics in airway inflammation

American Journal of Pathology

Volumn 185, Issue 11, 2015, Pages 2949-2968

  Le, Catherine T K ^a,b   Laidlaw, Grace ^a,b   Morehouse, Christopher A ^c   Naiman, Brian ^b,c   Brohawn, Philip ^c   Mustelin, Tomas ^c   Connor, Jane R ^c   McDonald, Donald M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; AZD 5180; CALGRANULIN B; CXCL1 CHEMOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPHRIN RECEPTOR B4; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MESSENGER RNA; MP 6XT 22; PADGEM PROTEIN; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG; ANG2 PROTEIN, MOUSE; PANCREATIC RIBONUCLEASE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL DIAMETER; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GERMFREE MOUSE; LYMPHANGIOGENESIS; MICROVASCULATURE; MOUSE; MYCOPLASMOSIS; NONHUMAN; PERICYTE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFLAMMATION; TRACHEAL BLOOD VESSEL; VASCULAR REMODELING; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DNA MICROARRAY; IMMUNOLOGY; INFLAMMATION; LYMPH VESSEL; LYMPHATIC SYSTEM; METABOLISM; MYCOPLASMA PULMONIS; PATHOLOGY; PHYSIOLOGY; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION;

ANIMALS; FEMALE; INFLAMMATION; LYMPHANGIOGENESIS; LYMPHATIC SYSTEM; LYMPHATIC VESSELS; MICE; MICE, INBRED C57BL; MYCOPLASMA INFECTIONS; MYCOPLASMA PULMONIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PERICYTES; RESPIRATORY SYSTEM; RIBONUCLEASE, PANCREATIC; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84945318797     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.07.010     Document Type: Article

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