Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis

Annals of the Rheumatic Diseases

Volumn 74, Issue 12, 2015, Pages 2254-2258

  Schelbergen, R F ^a   Geven, E J ^a   Van Den Bosch, M H J ^a   Eriksson, H ^b   Leanderson, T ^c   Vogl, T ^d   Roth, J ^d   Van De Loo, F A J ^a   Koenders, M I ^a   Van Der Kraan, P M ^a   Van Den Berg, W B ^a   Blom, A B ^a   Van Lent, P L E M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Active Biotech Research AB   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN B; INTERLEUKIN 6; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; PAQUINIMOD; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA; COLLAGENASE; IMMUNOSUPPRESSIVE AGENT; QUINOLINE DERIVATIVE; S100A9 PROTEIN, MOUSE;

ADAPTED PRITZKER OARSI SCORE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARBITRARY SCORE; ARTICLE; CHONDROPATHY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; KNEE CRUCIATE LIGAMENT; KNEE MENISCUS; MALE; MOUSE; MUSCULOSKELETAL SYSTEM PARAMETERS; NONHUMAN; OSTEOARTHRITIS; OSTEOPHYTE; PRIORITY JOURNAL; SCORING SYSTEM; SYNOVIAL THICKENING; SYNOVIUM; ANIMAL; ARTHRITIS, EXPERIMENTAL; ARTICULAR CARTILAGE; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; METABOLISM; PATHOLOGY;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CALGRANULIN B; CARTILAGE, ARTICULAR; COLLAGENASES; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; MICE; MICE, INBRED C57BL; QUINOLINES; SYNOVIAL MEMBRANE;

EID: 84945246230     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2014-206517     Document Type: Article

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