메뉴 건너뛰기




Volumn 15, Issue 1, 2015, Pages

Towards microbiome transplant as a therapy for periodontitis: An exploratory study of periodontitis microbial signature contrasted by oral health, caries and edentulism

Author keywords

Bacteriotherapy; Caries; Edentulism; Microbial transplant; Periodontitis; Red complex

Indexed keywords

ADULT; BACTERIUM; BIOFILM; CLASSIFICATION; DENTAL CARIES; GINGIVA; HUMAN; MICROBIOLOGY; MICROFLORA; MOUTH; PERIODONTITIS; TOOTH PLAQUE; TRANSPLANTATION;

EID: 84945237896     PISSN: None     EISSN: 14726831     Source Type: Journal    
DOI: 10.1186/s12903-015-0109-4     Document Type: Article
Times cited : (47)

References (73)
  • 1
    • 84873708523 scopus 로고    scopus 로고
    • The oral microbiome in health and disease
    • Wade WG. The oral microbiome in health and disease. Pharmacol Res. 2013;69:137-43.
    • (2013) Pharmacol Res , vol.69 , pp. 137-143
    • Wade, W.G.1
  • 2
    • 84859885188 scopus 로고    scopus 로고
    • Evidence of a robust resident bacteriophage population revealed through analysis of the human salivary virome
    • Pride DT, Salzman J, Haynes M, Rohwer F, Davis-Long C, White 3rd RA, et al. Evidence of a robust resident bacteriophage population revealed through analysis of the human salivary virome. ISME J. 2012;6:915-26.
    • (2012) ISME J , vol.6 , pp. 915-926
    • Pride, D.T.1    Salzman, J.2    Haynes, M.3    Rohwer, F.4    Davis-Long, C.5    White, R.A.6
  • 6
    • 20444471123 scopus 로고    scopus 로고
    • Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the "red complex", a prototype polybacterial pathogenic consortium in periodontiti
    • Holt SC, Ebersole JL. Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the "red complex", a prototype polybacterial pathogenic consortium in periodontitis. Periodontol 2000. 2005;38:72-122.
    • (2005) Periodontol 2000 , vol.38 , pp. 72-122
    • Holt, S.C.1    Ebersole, J.L.2
  • 7
    • 84865276077 scopus 로고    scopus 로고
    • Porphyromonas gingivalis as a potential community activist for disease
    • Darveau RP, Hajishengallis G, Curtis MA. Porphyromonas gingivalis as a potential community activist for disease. J Dent Res. 2012;91:816-20.
    • (2012) J Dent Res , vol.91 , pp. 816-820
    • Darveau, R.P.1    Hajishengallis, G.2    Curtis, M.A.3
  • 12
    • 77953616099 scopus 로고    scopus 로고
    • Periodontitis: a polymicrobial disruption of host homeostatis
    • Darveau RP. Periodontitis: a polymicrobial disruption of host homeostatis. Nat Rev Microbiol. 2010;8:481-90.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 481-490
    • Darveau, R.P.1
  • 13
    • 81755166205 scopus 로고    scopus 로고
    • Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement
    • Hajishengallis G, Liang S, Payne MA, Hashim A, Jotwani R, Eskan MA, et al. Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host Microbe. 2011;10:497-506.
    • (2011) Cell Host Microbe , vol.10 , pp. 497-506
    • Hajishengallis, G.1    Liang, S.2    Payne, M.A.3    Hashim, A.4    Jotwani, R.5    Eskan, M.A.6
  • 15
    • 33646086251 scopus 로고    scopus 로고
    • Molecular characterization of subject-specific oral microflora during initial colonization of enamel
    • Diaz PI, Chalmers NI, Rickard AH, Kong C, Milburn CL, Palmer Jr RJ, et al. Molecular characterization of subject-specific oral microflora during initial colonization of enamel. Appl Environ Microbiol. 2006;72:2837-48.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 2837-2848
    • Diaz, P.I.1    Chalmers, N.I.2    Rickard, A.H.3    Kong, C.4    Milburn, C.L.5    Palmer, R.J.6
  • 17
  • 19
    • 74949134895 scopus 로고    scopus 로고
    • Defining the healthy "core microbiome" of oral microbial communities
    • Zaura E, Keijser BJ, Huse SM, Crielaard W. Defining the healthy "core microbiome" of oral microbial communities. BMC Microbiol. 2009;15:259.
    • (2009) BMC Microbiol , vol.15 , pp. 259
    • Zaura, E.1    Keijser, B.J.2    Huse, S.M.3    Crielaard, W.4
  • 20
    • 1542360536 scopus 로고    scopus 로고
    • Specific antibiotics in the treatment of periodontitis-a proposed strategy
    • Beikler T, Prior K, Ehmke B, Flemmig TF. Specific antibiotics in the treatment of periodontitis-a proposed strategy. J Periodontol. 2004;75:169-75.
    • (2004) J Periodontol , vol.75 , pp. 169-175
    • Beikler, T.1    Prior, K.2    Ehmke, B.3    Flemmig, T.F.4
  • 21
    • 0030076741 scopus 로고    scopus 로고
    • Long-term evaluation of periodontal therapy, II Incidence of sites breaking down
    • Kaldahl WB, Kalkwarf KL, Patil KD, Molvar MP, Dyer JK. Long-term evaluation of periodontal therapy, II Incidence of sites breaking down. J Periodontol. 1996;67:103-8.
    • (1996) J Periodontol , vol.67 , pp. 103-108
    • Kaldahl, W.B.1    Kalkwarf, K.L.2    Patil, K.D.3    Molvar, M.P.4    Dyer, J.K.5
  • 22
    • 0031183771 scopus 로고    scopus 로고
    • Periodontal disease related to diabetic status. A pilot study of the response to periodontal therapy in type 1 diabetes
    • Tervonen T, Karjalainen K. Periodontal disease related to diabetic status. A pilot study of the response to periodontal therapy in type 1 diabetes. J Clin Periodontol. 1997;24:505-10.
    • (1997) J Clin Periodontol , vol.24 , pp. 505-510
    • Tervonen, T.1    Karjalainen, K.2
  • 23
    • 0019785244 scopus 로고
    • The significance of maintenance care in the treatment of periodontal disease
    • Axelsson P, Lindhe J. The significance of maintenance care in the treatment of periodontal disease. J Clin Periodontol. 1981;8:281-94.
    • (1981) J Clin Periodontol , vol.8 , pp. 281-294
    • Axelsson, P.1    Lindhe, J.2
  • 24
    • 0022744450 scopus 로고
    • Frequency distributions of periodontal attachment loss. Clinical and microbiological features
    • Haffajee AD, Socransky SS. Frequency distributions of periodontal attachment loss. Clinical and microbiological features. J Clin Periodontol. 1986;13:625-37.
    • (1986) J Clin Periodontol , vol.13 , pp. 625-637
    • Haffajee, A.D.1    Socransky, S.S.2
  • 25
    • 0026128425 scopus 로고
    • On the prevention of caries and periodontal diseas. Results of a 15-year longitudinal study in adults
    • Axelsson P, Lindhe J, Nystrom B. On the prevention of caries and periodontal disease. Results of a 15-year longitudinal study in adults. J Clin Periodontol. 1991;18:182-9.
    • (1991) J Clin Periodontol , vol.18 , pp. 182-189
    • Axelsson, P.1    Lindhe, J.2    Nystrom, B.3
  • 26
    • 4444250306 scopus 로고    scopus 로고
    • The long-term effect of a plaque control program on tooth mortality, caries and periodontal disease in adults. Results after 30 years of maintenance
    • Axelsson P, Nystrom B, Lindhe J. The long-term effect of a plaque control program on tooth mortality, caries and periodontal disease in adults. Results after 30 years of maintenance. J Clin Periodontol. 2004;31:749-57.
    • (2004) J Clin Periodontol , vol.31 , pp. 749-757
    • Axelsson, P.1    Nystrom, B.2    Lindhe, J.3
  • 27
    • 0034181189 scopus 로고    scopus 로고
    • Non-surgical periodontal therapy and tooth loss. A cohort study
    • Hujoel PP, Leroux BG, Selipsky H, White BA. Non-surgical periodontal therapy and tooth loss. A cohort study. J Periodontol. 2000;71:736-42.
    • (2000) J Periodontol , vol.71 , pp. 736-742
    • Hujoel, P.P.1    Leroux, B.G.2    Selipsky, H.3    White, B.A.4
  • 28
    • 0036886969 scopus 로고    scopus 로고
    • Tooth loss and pocket probing depths in compliant periodontally treated patients, a retrospective analysis
    • Konig J, Plagmann HC, Ruhling A, Kocher T. Tooth loss and pocket probing depths in compliant periodontally treated patients, a retrospective analysis. J Clin Periodontol. 2002;29:1092-100.
    • (2002) J Clin Periodontol , vol.29 , pp. 1092-1100
    • Konig, J.1    Plagmann, H.C.2    Ruhling, A.3    Kocher, T.4
  • 29
    • 0035286661 scopus 로고    scopus 로고
    • Longitudinal periodontal tissue alterations during supportive therapy. Findings from subjects with normal and high susceptibility to periodontal disease
    • Rosling B, Serino G, Hellstrom MK, Socransky SS, Lindhe J. Longitudinal periodontal tissue alterations during supportive therapy. Findings from subjects with normal and high susceptibility to periodontal disease. J Clin Periodontol. 2001;28:241-9.
    • (2001) J Clin Periodontol , vol.28 , pp. 241-249
    • Rosling, B.1    Serino, G.2    Hellstrom, M.K.3    Socransky, S.S.4    Lindhe, J.5
  • 30
    • 0001412472 scopus 로고
    • Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis
    • Eiseman B, Silen W, Bascom GS, Kauvar AJ. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery. 1958;44:854-9.
    • (1958) Surgery , vol.44 , pp. 854-859
    • Eiseman, B.1    Silen, W.2    Bascom, G.S.3    Kauvar, A.J.4
  • 31
    • 84869395353 scopus 로고    scopus 로고
    • Should we standardize the 1, 700-year-old fecal microbiota transplantation?
    • Zhang F, Luo W, Shi Y, Fan Z, Ji G. Should we standardize the 1, 700-year-old fecal microbiota transplantation? Am J Gastroenterol. 2012;107:1755.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1755
    • Zhang, F.1    Luo, W.2    Shi, Y.3    Fan, Z.4    Ji, G.5
  • 32
    • 84875952542 scopus 로고    scopus 로고
    • Fecal microbiota transplantation for Clostridium difficile infection: systematic review and meta-analysis
    • Kassam Z, Lee CH, Yuan Y, Hunt RH. Fecal microbiota transplantation for Clostridium difficile infection: systematic review and meta-analysis. Am J Gastroenterol. 2013;108:500-8.
    • (2013) Am J Gastroenterol , vol.108 , pp. 500-508
    • Kassam, Z.1    Lee, C.H.2    Yuan, Y.3    Hunt, R.H.4
  • 33
    • 84931295496 scopus 로고    scopus 로고
    • Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook
    • Kelly CR, Kahn S, Kashyap P, Laine L, Rubin D, Atreja A, et al. Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook. Gastroenterology. 2015;149:223-37.
    • (2015) Gastroenterology , vol.149 , pp. 223-237
    • Kelly, C.R.1    Kahn, S.2    Kashyap, P.3    Laine, L.4    Rubin, D.5    Atreja, A.6
  • 34
    • 34547472537 scopus 로고    scopus 로고
    • Case definitions for use in population-based surveillance of periodontitis
    • Page RC, Eke PI. Case definitions for use in population-based surveillance of periodontitis. J Periodontol. 2007;78:1387-99.
    • (2007) J Periodontol , vol.78 , pp. 1387-1399
    • Page, R.C.1    Eke, P.I.2
  • 35
    • 84856656925 scopus 로고    scopus 로고
    • Trends in oral health status: United States, 1988-1994 and 1999-2004. National Center for Health Statistics
    • Dye BA, Tan S, Smith V, Lewis BG, Barker LK, Thornton-Evans G, et al. Trends in oral health status: United States, 1988-1994 and 1999-2004. National Center for Health Statistics. Vital Health Stat. 2007;11:248.
    • (2007) Vital Health Stat , vol.11 , pp. 248
    • Dye, B.A.1    Tan, S.2    Smith, V.3    Lewis, B.G.4    Barker, L.K.5    Thornton-Evans, G.6
  • 36
    • 33748522747 scopus 로고    scopus 로고
    • Sampling strategy for intraoral detection of periodontal pathogens before and following periodontal therapy
    • Beikler T, Schnitzer S, Abdeen G, Ehmke B, Eisenacher M, Flemmig TF. Sampling strategy for intraoral detection of periodontal pathogens before and following periodontal therapy. J Periodontol. 2006;77:1323-3132.
    • (2006) J Periodontol , vol.77 , pp. 1323-3132
    • Beikler, T.1    Schnitzer, S.2    Abdeen, G.3    Ehmke, B.4    Eisenacher, M.5    Flemmig, T.F.6
  • 37
    • 84859514086 scopus 로고    scopus 로고
    • Randomized controlled trial assessing efficacy and safety of glycine powder air polishing in moderate to deep periodontal pockets
    • Flemmig TF, Arushanov D, Daubert D, Rothen M, Mueller G, Leroux BG. Randomized controlled trial assessing efficacy and safety of glycine powder air polishing in moderate to deep periodontal pockets. J Periodontol. 2012;83:444-52.
    • (2012) J Periodontol , vol.83 , pp. 444-452
    • Flemmig, T.F.1    Arushanov, D.2    Daubert, D.3    Rothen, M.4    Mueller, G.5    Leroux, B.G.6
  • 38
    • 53549118607 scopus 로고    scopus 로고
    • The metagenomics RAST server-a public resource for the automatic phylogenetic and functional analysis of metagenomes
    • Meyer F, Paarmann D, D'Souza M, Olson R, Glass EM, Kubal M, et al. The metagenomics RAST server-a public resource for the automatic phylogenetic and functional analysis of metagenomes. BMC Bioinf. 2008;9:386.
    • (2008) BMC Bioinf , vol.9 , pp. 386
    • Meyer, F.1    Paarmann, D.2    D'Souza, M.3    Olson, R.4    Glass, E.M.5    Kubal, M.6
  • 41
    • 0036777257 scopus 로고    scopus 로고
    • Selection of antimicrobial agents in periodontal therapy
    • Slots J. Selection of antimicrobial agents in periodontal therapy. J Periodontal Res. 2002;37:389-98.
    • (2002) J Periodontal Res , vol.37 , pp. 389-398
    • Slots, J.1
  • 42
    • 0002154022 scopus 로고    scopus 로고
    • A new method for non-parametric multivariate analysis of variance
    • Anderson MJ. A new method for non-parametric multivariate analysis of variance. Austral Ecol. 2001;26:32-46.
    • (2001) Austral Ecol , vol.26 , pp. 32-46
    • Anderson, M.J.1
  • 43
    • 0035133496 scopus 로고    scopus 로고
    • Fitting multivariate models to community data: a comment on distance-based redundancy analysis
    • McArdle BH, Anderson MJ. Fitting multivariate models to community data: a comment on distance-based redundancy analysis. Ecology. 2001;82:290-7.
    • (2001) Ecology , vol.82 , pp. 290-297
    • McArdle, B.H.1    Anderson, M.J.2
  • 45
    • 84861342868 scopus 로고    scopus 로고
    • Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing
    • Griffen AL, Beall CJ, Campbell JH, Firestone ND, Kumar PS, Yang ZK, et al. Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing. ISME J. 2012;6:1176-85.
    • (2012) ISME J , vol.6 , pp. 1176-1185
    • Griffen, A.L.1    Beall, C.J.2    Campbell, J.H.3    Firestone, N.D.4    Kumar, P.S.5    Yang, Z.K.6
  • 47
    • 84859751086 scopus 로고    scopus 로고
    • Pyrosequencing reveals unique microbial signatures associated with healthy and failing dental implants
    • Kumar PS, Mason MR, Brooker MR, O'Brien K. Pyrosequencing reveals unique microbial signatures associated with healthy and failing dental implants. J Clin Periodontol. 2012;39:425-33.
    • (2012) J Clin Periodontol , vol.39 , pp. 425-433
    • Kumar, P.S.1    Mason, M.R.2    Brooker, M.R.3    O'Brien, K.4
  • 48
    • 84904993698 scopus 로고    scopus 로고
    • Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis
    • Duran-Pinedo AE, Chen T, Teles R, Starr JR, Wang X, Krishnan K, et al. Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis. ISME J. 2014;8:1659-72.
    • (2014) ISME J , vol.8 , pp. 1659-1672
    • Duran-Pinedo, A.E.1    Chen, T.2    Teles, R.3    Starr, J.R.4    Wang, X.5    Krishnan, K.6
  • 50
    • 10444246722 scopus 로고    scopus 로고
    • The effectiveness of a toothpaste containing triclosan and polyvinyl-methyl ether maleic acid copolymer in improving plaque control and gingival health: a systematic review
    • Davies RM, Ellwood RP, Davies GM. The effectiveness of a toothpaste containing triclosan and polyvinyl-methyl ether maleic acid copolymer in improving plaque control and gingival health: a systematic review. J Clin Periodontol. 2004;31:1029-33.
    • (2004) J Clin Periodontol , vol.31 , pp. 1029-1033
    • Davies, R.M.1    Ellwood, R.P.2    Davies, G.M.3
  • 51
    • 84869006781 scopus 로고    scopus 로고
    • Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology
    • Hajishengallis G, Lamont RJ. Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology. Mol Oral Microbiol. 2012;27:409-19.
    • (2012) Mol Oral Microbiol , vol.27 , pp. 409-419
    • Hajishengallis, G.1    Lamont, R.J.2
  • 53
    • 77649218783 scopus 로고    scopus 로고
    • Relationships among gingival crevicular fluid biomarkers, clinical parameters of periodontal disease, and the subgingival microbiota
    • Teles R, Sakellari D, Teles F, Konstantinidis A, Kent R, Socransky S, et al. Relationships among gingival crevicular fluid biomarkers, clinical parameters of periodontal disease, and the subgingival microbiota. J Periodontol. 2010;81:89-98.
    • (2010) J Periodontol , vol.81 , pp. 89-98
    • Teles, R.1    Sakellari, D.2    Teles, F.3    Konstantinidis, A.4    Kent, R.5    Socransky, S.6
  • 55
    • 84878796781 scopus 로고    scopus 로고
    • Oral microbiome of deep and shallow dental pockets in chronic periodontitis
    • Ge X, Rodriguez R, Trinh M, Gunsolley J, Xu P. Oral microbiome of deep and shallow dental pockets in chronic periodontitis. PLoS One. 2013;8, e65520.
    • (2013) PLoS One , vol.8
    • Ge, X.1    Rodriguez, R.2    Trinh, M.3    Gunsolley, J.4    Xu, P.5
  • 56
    • 78650161976 scopus 로고    scopus 로고
    • Quantifying microbial communities with 454 pyrosequencing: does read abundance count?
    • Amend AS, Seifert KA, Bruns TD. Quantifying microbial communities with 454 pyrosequencing: does read abundance count? Mol Ecol. 2010;19:5555-65.
    • (2010) Mol Ecol , vol.19 , pp. 5555-5565
    • Amend, A.S.1    Seifert, K.A.2    Bruns, T.D.3
  • 57
    • 84876354602 scopus 로고    scopus 로고
    • Physicochemical foundations underpinning microarray and next-generation sequencing experiments
    • Harrison A, Binder H, Buhot A, Burden CJ, Carlon E, Gibas C, et al. Physicochemical foundations underpinning microarray and next-generation sequencing experiments. Nucleic Acids Res. 2013;41:2779-96.
    • (2013) Nucleic Acids Res , vol.41 , pp. 2779-2796
    • Harrison, A.1    Binder, H.2    Buhot, A.3    Burden, C.J.4    Carlon, E.5    Gibas, C.6
  • 61
    • 84861209251 scopus 로고    scopus 로고
    • Effect of periodontal pathogens on the metatranscriptome of a healthy multispecies biofilm model
    • Frias-Lopez J, Duran-Pinedo A. Effect of periodontal pathogens on the metatranscriptome of a healthy multispecies biofilm model. J Bacteriol. 2012;194:2082-95.
    • (2012) J Bacteriol , vol.194 , pp. 2082-2095
    • Frias-Lopez, J.1    Duran-Pinedo, A.2
  • 62
    • 33747853795 scopus 로고    scopus 로고
    • The breadth of bacterial diversity in the human periodontal pocket and other oral site
    • Paster BJ, Olsen I, Aas JA, Dewhirst FE. The breadth of bacterial diversity in the human periodontal pocket and other oral sites. Periodontol 2000. 2006;42:80-7.
    • (2006) Periodontol 2000 , vol.42 , pp. 80-87
    • Paster, B.J.1    Olsen, I.2    Aas, J.A.3    Dewhirst, F.E.4
  • 63
    • 84896708902 scopus 로고    scopus 로고
    • Microbiota dynamics in patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection
    • Song Y, Garg S, Girotra M, Maddox C, von Rosenvinge EC, Dutta A, et al. Microbiota dynamics in patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection. PLoS One. 2013;8, e81330.
    • (2013) PLoS One , vol.8
    • Song, Y.1    Garg, S.2    Girotra, M.3    Maddox, C.4    von Rosenvinge, E.C.5    Dutta, A.6
  • 64
    • 33747826870 scopus 로고    scopus 로고
    • The effect of periodontal therapy on the composition of the subgingival microbiot
    • Haffajee AD, Teles RP, Socransky SS. The effect of periodontal therapy on the composition of the subgingival microbiota. Periodontol 2000. 2006;42:219-58.
    • (2006) Periodontol 2000 , vol.42 , pp. 219-258
    • Haffajee, A.D.1    Teles, R.P.2    Socransky, S.S.3
  • 65
    • 84874588704 scopus 로고    scopus 로고
    • The clinical effect of scaling and root planning and the concomitant administration of systemic amoxicillin and metronidazole: a systematic review
    • Zandbergen D, Slot DE, Cobb CM, Van der Weijden FA. The clinical effect of scaling and root planning and the concomitant administration of systemic amoxicillin and metronidazole: a systematic review. J Periodontol. 2013;84:332-51.
    • (2013) J Periodontol , vol.84 , pp. 332-351
    • Zandbergen, D.1    Slot, D.E.2    Cobb, C.M.3    Van der Weijden, F.A.4
  • 66
    • 0035293454 scopus 로고    scopus 로고
    • One-stage full-mouth disinfection. Long-term microbiological results analyzed by checkerboard DNA-DNA hybridization
    • De Soete M, Mongardini C, Peuwels M, Haffajee A, Socransky S, van Steenberghe D, et al. One-stage full-mouth disinfection. Long-term microbiological results analyzed by checkerboard DNA-DNA hybridization. J Periodontol. 2001;72:374-82.
    • (2001) J Periodontol , vol.72 , pp. 374-382
    • De Soete, M.1    Mongardini, C.2    Peuwels, M.3    Haffajee, A.4    Socransky, S.5    van Steenberghe, D.6
  • 67
    • 20744435325 scopus 로고    scopus 로고
    • Adjunctive antimicrobial therapy of periodontitis, long-term effects on disease progression and oral colonization
    • Ehmke B, Moter A, Beikler T, Milian E, Flemmig TF. Adjunctive antimicrobial therapy of periodontitis, long-term effects on disease progression and oral colonization. J Periodontol. 2005;76:749-59.
    • (2005) J Periodontol , vol.76 , pp. 749-759
    • Ehmke, B.1    Moter, A.2    Beikler, T.3    Milian, E.4    Flemmig, T.F.5
  • 68
    • 0015402247 scopus 로고
    • A study of the effects of antiseptic agents and a pulsating irrigating device on plaque and gingivitis
    • Lobene RR, Soparkar PM, Hein JW, Quigley GA. A study of the effects of antiseptic agents and a pulsating irrigating device on plaque and gingivitis. J Periodontol. 1972;43:564-8.
    • (1972) J Periodontol , vol.43 , pp. 564-568
    • Lobene, R.R.1    Soparkar, P.M.2    Hein, J.W.3    Quigley, G.A.4
  • 70
    • 0020824776 scopus 로고
    • Effect of sodium hypochlorite solution on the subgingival microflora of juvenile periodontitis lesions
    • Adcock JE, Berry Jr WC, Kalkwarf KL. Effect of sodium hypochlorite solution on the subgingival microflora of juvenile periodontitis lesions. Pediatr Dent. 1983;5:190-4.
    • (1983) Pediatr Dent , vol.5 , pp. 190-194
    • Adcock, J.E.1    Berry, W.C.2    Kalkwarf, K.L.3
  • 71
    • 0035379286 scopus 로고    scopus 로고
    • An in vitro evaluation of the antimicrobial efficacy of irrigants on biofilms of root canal isolates
    • Spratt DA, Pratten J, Wilson M, Gulabivala K. An in vitro evaluation of the antimicrobial efficacy of irrigants on biofilms of root canal isolates. Int Endod J. 2001;34:300-7.
    • (2001) Int Endod J , vol.34 , pp. 300-307
    • Spratt, D.A.1    Pratten, J.2    Wilson, M.3    Gulabivala, K.4
  • 73
    • 84927750224 scopus 로고    scopus 로고
    • Serial fecal microbiota transplantation alters mucosal gene expression in pediatric ulcerative colitis
    • Kellermayer R, Nagy-Szakal D, Harris RA, Luna RA, Pitashny M, Schady D, et al. Serial fecal microbiota transplantation alters mucosal gene expression in pediatric ulcerative colitis. Am J Gastroenterol. 2015;110:604-6.
    • (2015) Am J Gastroenterol , vol.110 , pp. 604-606
    • Kellermayer, R.1    Nagy-Szakal, D.2    Harris, R.A.3    Luna, R.A.4    Pitashny, M.5    Schady, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.