The estimated frequency of Antiphospholipid antibodies in young adults with cerebrovascular events: A systematic review

Annals of the Rheumatic Diseases

Volumn 74, Issue 11, 2015, Pages 2028-2033

  Sciascia, Savino ^a,b   Sanna, Giovanni ^a   Khamashta, Munther A ^a   Cuadrado, Maria Jose ^a   Erkan, Doruk ^c   Andreoli, Laura ^d   Bertolaccini, Maria Laura ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b UNIVERSITY OF TURIN   (Italy)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d UNIVERSITY OF BRESCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 GLYCOPROTEIN 1 ANTIBODY; CARDIOLIPIN ANTIBODY; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY; AUTOANTIBODY; BETA2 GLYCOPROTEIN 1;

ANTIBODY DETECTION; ARTICLE; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR DISEASE; HUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SYSTEMATIC REVIEW; TRANSIENT ISCHEMIC ATTACK; ADOLESCENT; ADULT; IMMUNOLOGY; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; ANTIBODIES, ANTICARDIOLIPIN; ANTIBODIES, ANTIPHOSPHOLIPID; AUTOANTIBODIES; BETA 2-GLYCOPROTEIN I; HUMANS; ISCHEMIC ATTACK, TRANSIENT; LUPUS COAGULATION INHIBITOR; MIDDLE AGED; STROKE; YOUNG ADULT;

EID: 84945208968     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2014-205663     Document Type: Article

References (63)

1. (WHO) WHO. Cardiovascular Diseases. Geneva, Switzerland: WHO, 2009; WHO Fact Sheet 37.
2. Adams HP Jr, Kappelle LJ, Biller J, et al. Ischemic stroke in young adults. Experience in 329 patients enrolled in the Iowa Registry of stroke in young adults. Arch Neurol 1995;52:491-5.
3. Ruiz-Irastorza G, Crowther M, Branch W, et al. Antiphospholipid syndrome. Lancet 2010;376:1498-509.
4. Nencini P, Baruffi MC, Abbate R, et al. Lupus anticoagulant and anticardiolipin antibodies in young adults with cerebral ischemia. Stroke 1992;23:189-93.
5. Andreoli L, Chighizola CB, Banzato A, et al. The estimated frequency of antiphospholipid antibodies in patients with pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis. Arthritis Care Res 2013;65:1869-73.
6. R L. Kappa as a Measure of Concordance in Categorical Sorting. http://facultyvassaredu/lowry/kappahtml (accessed 28 May 2013).
7. Barnabe C, Faris PD, Quan H. Canadian pregnancy outcomes in rheumatoid arthritis and systemic lupus erythematosus. Int J Rheumatol 2011;2011:345727.
8. Miyakis S, Lockshin MD, Atsumi T, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006;4:295-306.
9. Wilson WA, Gharavi AE, Koike T, et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop. Arthritis Rheum 1999;42:1309-11.
10. Galli M, Luciani D, Bertolini G, et al. Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood 2003;101:1827-32.
11. Galli M, Luciani D, Bertolini G, et al. Anti-beta 2-glycoprotein I, antiprothrombin antibodies, and the risk of thrombosis in the antiphospholipid syndrome. Blood 2003;102:2717-23.
12. Barinagarrementeria F, Cantu-Brito C, De La Pena A, et al. Prothrombotic states in young people with idiopathic stroke. A prospective study. Stroke 1994;25:287-90.
13. Dharmasaroja PA, Muengtaweepongsa S, Lechawanich C, et al. Causes of ischemic stroke in young adults in Thailand: a pilot study. J Stroke Cerebrovasc Dis 2011;20:247-50.
14. Dragoni F, Chiarotti F, Rosano G, et al. Thrombophilic screening in young patients (< 40 years) with idiopathic ischemic stroke: a controlled study. Thromb Res 2011;127:85-90.
15. Milandre L, Brosset C, Habib G, et al. [Cerebral infarction in patients aged 16 to 35 years. Prospective study of 52 cases]. Presse Med 1994;23:1603-8.
16. Van Goor MP, Alblas CL, Leebeek FW, et al. Do antiphospholipid antibodies increase the long-term risk of thrombotic complications in young patients with a recent TIA or ischemic stroke? Acta Neurol Scand 2004;109:410-15.
17. Belvis R, Santamaria A, Marti-Fabregas J, et al. Patent foramen ovale and prothrombotic markers in young stroke patients. Blood Coagul Fibrinolysis 2007;18:537-42.
18. Biswas A, Ranjan R, Meena A, et al. Prothrombotic factors and the risk of acute onset non-cardioembolic stroke in young Asian Indians. Thromb Res 2009;124:397-402.
19. Blohorn A, Guegan-Massardier E, Triquenot A, et al. Antiphospholipid antibodies in the acute phase of cerebral ischaemia in young adults: a descriptive study of 139 patients. Cerebrovasc Dis 2002;13:156-62.
20. Brey RL, Hart RG, Sherman DG, et al. Antiphospholipid antibodies and cerebral ischemia in young people. Neurology 1990;40:1190-6.
21. Brey RL, Abbott RD, Curb JD, et al. beta (2)-Glycoprotein 1-dependent anticardiolipin antibodies and risk of ischemic stroke and myocardial infarction: the honolulu heart program. Stroke 2001;32:1701-6.
22. Urbanus RT, Siegerink B, Roest M, et al. Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study. Lancet Neurol 2009;8:998-1005.
23. Cojocaru IM, Cojocaru M, Burcin C, et al. Evaluation of antiphospholipid antibodies in young women with ischemic stroke. Rom J Intern Med 2007;45:201-4.
24. Brey RL, Stallworth CL, McGlasson DL, et al. Antiphospholipid antibodies and stroke in young women. Stroke 2002;33:2396-400.
25. Chancellor AM, Glasgow GL, Ockelford PA, et al. Etiology, prognosis, and hemostatic function after cerebral infarction in young adults. Stroke 1989;20:477-82.
26. Cojocaru IM, Cojocaru M, Tanasescu R, et al. Detecting anti-prothrombin antibodies in young women with acute ischemic stroke. Rom J Intern Med 2008;46:337-41.
27. Czlonkowska A, Meurer M, Palasik W, et al. Anticardiolipin antibodies, a disease marker for ischemic cerebrovascular events in a younger patient population? Acta Neurol Scand 1992;86:304-7.
28. Damoiseaux J, Peeters L, Hupperts R, et al. Prevalence of anticardiolipin antibodies in patient cohorts with distinct clinical manifestations of the antiphospholipid syndrome. Ann NYAcad Sci 2009;1173:146-51.
29. Ellis MH, Kesler A, Friedman Z, et al. Value of prothrombin fragment 1.2 (F 1.2) in the diagnosis of stroke in young patients with antiphospholipid antibodies. Clin Appl Thromb Hemost 2000;6:61-4.
30. Ferro D, Quintarelli C, Rasura M, et al. Lupus anticoagulant and the fibrinolytic system in young patients with stroke. Stroke 1993;24:368-70.
31. Talebi M, Jafar Majidi J, Arami M, et al. Evaluation of antiphospholipid antibodies in youths suffering from cerebral ischemia. Iran J Neuro 2005;15:26.
32. Hart RG, Miller VT, Coull BM, et al. Cerebral infarction associated with lupus anticoagulants-preliminary report. Stroke 1984;15:114-18.
33. Husham YMA ZA. Anti-beta;2-Glycoprotein I Autoantibody Expression as a Potential Biomarker for Strokes in Patients with Anti-Phospholipid Syndrome. J Immunotoxicol 2008;5:173-7.
34. Janssen AW, De Leeuw FE, Janssen MC. Risk factors for ischemic stroke and transient ischemic attack in patients under age 50. J Thromb Thrombolysis 2011;31:85-91.
35. Kahwa EK, Sargeant LA, McFarlane-Anderson N, et al. Anticardiolipin antibodies and risk of thromboembolic disease in young Jamaican women. J Cardiovasc Risk 2001;8:349-54.
36. Martinez-Aviles P, Barba R, Andujar C, et al. [Cerebrovascular accident in young adults. A study of 52 cases]. Rev Neurol 1996;24:443-7.
37. Mishra MN, Rohatgi S. Antiphospholipid antibodies in young Indian patients with stroke. J Postgrad Med 2009;55:161-4.
38. Panagariya A, Garg A, Sureka RK. Antiphospholipid antibody positive young stroke: an analysis of 12 cases. J Postgrad Med 2000;46:258-61.
39. Singh K, Gaiha M, Shome DK, et al. The association of antiphospholipid antibodies with ischaemic stroke and myocardial infarction in young and their correlation: a preliminary study. J Assoc Physicians India 2001;49:527-9.
40. Siqueira Neto JI SA, Cabette Fábio S, Sakamoto AC. Anticorpos antifosfolípides em 66 pacientes com infarto cerebral entre 15 e 40 anos. Arq Neuropsiquiatr 1996;54:584-9.
41. Skidmore FM, Fradkin KD, Wiliams LS, et al. Presentation, etiology, and outcome of stroke in pregnancy and puerperium. Neurology 2000;54:A409-A409.
42. Tietjen GE, Levine SR, Brown E, et al. Factors That Predict Antiphospholipid Immunoreactivity in Young-People with Transient Focal Neurological Events. Arch Neurol 1993;50:833-6.
43. Toschi V, Motta A, Castelli C, et al. High prevalence of antiphosphatidylinositol antibodies in young patients with cerebral ischemia of undetermined cause. Stroke 1998;29:1759-64.
44. Dobrynina LA, Kalashnikova LA, Pavlova LN. [Ischemic stroke in young age]. Zh Nevrol Psikhiatr Im SSKorsakova 2011;111:4-8.
45. Yokus O, Albayrak M, Balcik OS, et al. Risk factors for thrombophilia in young adults presenting with thrombosis. Int J Hematol 2009;90:583-90.
46. De Silva R, Gamage R, Wewelwala C, et al. Young strokes in Sri Lanka: an unsolved problem. J Stroke Cerebrovasc Dis 2009;18:304-8.
47. Saadatnia M, Zare M, Haghighi S, et al. High frequency of IgM antiphospholipid antibodies in young Iranian patients with stroke. Neurosciences (Riyadh) 2007;12:124-6.
48. Gaspersic N, Rot U, Cucnik S, et al. Low prevalence of antiphospholipid antibodies in a series of young patients with cerebrovascular disease. Clin Exp Rheumatol 2003;21:680.
49. Daif AK, Jabbar MA, Ogunniyi A. Anticardiolipin antibodies in young Saudis with ischemic stroke. Ann Saudi Med 1998;18:73-4.
50. Munts AG, Van Genderen PJ, Dippel DW, et al. Coagulation disorders in young adults with acute cerebral ischaemia. J Neurol 1998;245:21-5.
51. Nagaraja D, Christopher R, Manjari T. Anticardiolipin antibodies in ischemic stroke in the young: Indian experience. J Neurol Sci 1997;150:137-42.
52. Kalashnikova LA, Nasonov EL, Aleksandrova EN, et al. [Antibodies to phospholipids and ischemic disorders of cerebral circulation in young age]. Zh Nevrol Psikhiatr Im SSKorsakova 1997;97:59-65.
53. Girmenia F, Argentino C, Di Scipio E, et al. Antiphospholipid antibodies and cerebral artery dissection: two frequent causes of brain ischemia in young adults. Italian J Neurol Sci 1994;15:221-7.
54. De Jong AW, Hart W, Terburg M, et al. Cardiolipin antibodies and lupus anticoagulant in young patients with a cerebrovascular accident in the past. Neth J Med 1993;42:93-8.
55. Nedeltchev K, Der Maur TA, Georgiadis D, et al. Ischaemic stroke in young adults: predictors of outcome and recurrence. J Neurol Neurosurg Psychiatry 2005;76:191-5.
56. Bushnell CD, Goldstein LB. Diagnostic testing for coagulopathies in patients with ischemic stroke. Stroke 2000;31:3067-78.
57. Andreoli L, Chighizola CB, Banzato A, et al. Estimated Frequency of Antiphospholipid Antibodies in Patients With Pregnancy Morbidity, Stroke, Myocardial Infarction, and Deep Vein Thrombosis: A Critical Review of the Literature. Arthritis Care Res 2013;65:1869-73.
58. Reid MC, Lachs MS, Feinstein AR. Use of methodological standards in diagnostic test research. Getting better but still not good. JAMA 1995;274:645-51.
59. Favaloro EJ, Silvestrini R, Mohammed A. Clinical utility of anticardiolipin antibody assays: high inter-laboratory variation and limited consensus by participants of external quality assurance programs signals a cautious approach. Pathology 1999;31:142-7.
60. Pengo V, Ruffatti A, Legnani C, et al. Clinical course of high-risk patients diagnosed with antiphospholipid syndrome. J Thromb Haemost 2010;8:237-42.
61. Sciascia S, Cosseddu D, Montaruli B, et al. Risk Scale for the diagnosis of antiphospholipid syndrome. Ann Rheum Dis 2011;70:1517-18.
62. Pengo V, Ruffatti A, Legnani C, et al. Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study. Blood 2011;118:4714-18.
63. Sciascia S, Murru V, Sanna G, et al. Clinical accuracy for diagnosis of antiphospholipid syndrome in systemic lupus erythematosus: evaluation of 23 possible combinations of antiphospholipid antibody specificities. J Thromb Haemost 2012;10:2512-18.