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Volumn 8, Issue 6, 2015, Pages 1212-1225

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; ETANERCEPT; GLUCOCORTICOID; THYMIC STROMAL LYMPHOPOIETIN; TUMOR NECROSIS FACTOR ALPHA; ANTIASTHMATIC AGENT; IMMUNOSUPPRESSIVE AGENT;

EID: 84945188133     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.12     Document Type: Article
Times cited : (73)

References (59)
  • 1
    • 84874585409 scopus 로고    scopus 로고
    • New insights into the anti-inflammatory mechanisms of glucocorticoids: An emerging role for glucocorticoid-receptor-mediated transactivation
    • Vandevyver S., Dejager L., Tuckermann J., & Libert C. New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation. Endocrinology 154, 993-1007 (2013
    • (2013) Endocrinology , vol.154 , pp. 993-1007
    • Vandevyver, S.1    Dejager, L.2    Tuckermann, J.3    Libert, C.4
  • 2
    • 79953871100 scopus 로고    scopus 로고
    • Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor
    • Surjit M., et al. Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor. Cell 145, 224-241 (2011
    • (2011) Cell , vol.145 , pp. 224-241
    • Surjit, M.1
  • 3
    • 33846136095 scopus 로고    scopus 로고
    • The limitations of severe asthma: The results of a european survey
    • Dockrell M., Partridge M.R., & Valovirta E. The limitations of severe asthma: the results of a European survey. Allergy 62, 134-141 (2007
    • (2007) Allergy , vol.62 , pp. 134-141
    • Dockrell, M.1    Partridge, M.R.2    Valovirta, E.3
  • 4
    • 33747750597 scopus 로고    scopus 로고
    • The mechanisms, diagnosis, and management of severe asthma in adults
    • Holgate S.T., & Polosa R. The mechanisms, diagnosis, and management of severe asthma in adults. Lancet 368, 780-793 (2006
    • (2006) Lancet , vol.368 , pp. 780-793
    • Holgate, S.T.1    Polosa, R.2
  • 5
    • 34249912039 scopus 로고    scopus 로고
    • Severe asthma in adults: What are the important questions?
    • Chanez P., et al. Severe asthma in adults: what are the important questions?. J. Allergy Clin. Immunol. 119, 1337-1348 (2007
    • (2007) J. Allergy Clin. Immunol , vol.119 , pp. 1337-1348
    • Chanez, P.1
  • 6
    • 77954033984 scopus 로고    scopus 로고
    • New therapies for asthma: Is there any progress?. Trends Pharmacol
    • Barnes P.J. New therapies for asthma: is there any progress?. Trends Pharmacol. Sci. 31, 335-343 (2010
    • (2010) Sci , vol.31 , pp. 335-343
    • Barnes, P.J.1
  • 7
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: New insights into key pathogenic mechanisms in a complex, heterogeneous disease
    • Anderson G.P. Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet 372, 1107-1119 (2008
    • (2008) Lancet , vol.372 , pp. 1107-1119
    • Anderson, G.P.1
  • 8
    • 84860679595 scopus 로고    scopus 로고
    • Asthma phenotypes: The evolution from clinical to molecular approaches
    • Wenzel S.E. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat. Med. 18, 716-725 (2012
    • (2012) Nat. Med , vol.18 , pp. 716-725
    • Wenzel, S.E.1
  • 9
    • 84860691114 scopus 로고    scopus 로고
    • The airway epithelium in asthma
    • Lambrecht B.N., & Hammad H. The airway epithelium in asthma. Nat. Med. 18, 684-692 (2012
    • (2012) Nat. Med , vol.18 , pp. 684-692
    • Lambrecht, B.N.1    Hammad, H.2
  • 11
    • 0343527389 scopus 로고    scopus 로고
    • Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance
    • Ordonez C.L., Shaughnessy T.E., Matthay M.A., & Fahy J.V. Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: clinical and biologic significance. Am. J. Respir. Crit. Care Med. 161, 1185-1190 (2000
    • (2000) Am. J. Respir. Crit. Care Med , vol.161 , pp. 1185-1190
    • Ordonez, C.L.1    Shaughnessy, T.E.2    Matthay, M.A.3    Fahy, J.V.4
  • 13
    • 0028989599 scopus 로고
    • Tnf-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation
    • Lukacs N.W., Strieter R.M., Chensue S.W., Widmer M., & Kunkel S.L. Tnf-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation. J. Immunol. 154, 5411-5417 (1995
    • (1995) J. Immunol , vol.154 , pp. 5411-5417
    • Lukacs, N.W.1    Strieter, R.M.2    Chensue, S.W.3    Widmer, M.4    Kunkel, S.L.5
  • 14
    • 28244479315 scopus 로고    scopus 로고
    • Tumour necrosis factor (TNF alpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma
    • Howarth P.H., et al. Tumour necrosis factor (TNF alpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma. Thorax 60, 1012-1018 (2005
    • (2005) Thorax , vol.60 , pp. 1012-1018
    • Howarth, P.H.1
  • 15
    • 32644490529 scopus 로고    scopus 로고
    • Evidence of a role of tumor necrosis factor alpha in refractory asthma
    • Berry M.A., et al. Evidence of a role of tumor necrosis factor alpha in refractory asthma. N. Engl. J. Med. 354, 697-708 (2006
    • (2006) N. Engl. J. Med , vol.354 , pp. 697-708
    • Berry, M.A.1
  • 16
    • 62549084077 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma
    • Wenzel S.E., et al. A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am. J Respir. Crit. Care Med. 179, 549-558 (2009
    • (2009) Am. J Respir. Crit. Care Med , vol.179 , pp. 549-558
    • Wenzel, S.E.1
  • 17
    • 79957987328 scopus 로고    scopus 로고
    • Efficacy and safety of etanercept inmoderate-to-severe asthma: A randomised, controlled trial
    • Holgate S.T., et al. Efficacy and safety of etanercept inmoderate-to-severe asthma: a randomised, controlled trial. Eur. Respirat. J. 37, 1352-1359 (2011
    • (2011) Eur. Respirat. J. , vol.37 , pp. 1352-1359
    • Holgate, S.T.1
  • 18
    • 79955781860 scopus 로고    scopus 로고
    • Inflammatory signatures for eosinophilic vs neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints
    • Bogaert P., et al. Inflammatory signatures for eosinophilic vs. neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints. Am. J. Physiol. Lung Cell. Mol. Physiol 300, L679-L690 (2011
    • (2011) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.300 , pp. L679-L690
    • Bogaert, P.1
  • 20
    • 0023091309 scopus 로고
    • Tumor necrosis factor is chemotactic for monocytes and polymorphonuclear leukocytes
    • Ming W.J., Bersani L., & Mantovani A. Tumor necrosis factor is chemotactic for monocytes and polymorphonuclear leukocytes. J. Immunol. 138, 1469-1474 (1987
    • (1987) J. Immunol , vol.138 , pp. 1469-1474
    • Ming, W.J.1    Bersani, L.2    Mantovani, A.3
  • 21
    • 84878589884 scopus 로고    scopus 로고
    • Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium
    • Van Hauwermeiren F., et al. Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium. J. Clin. Invest. 123, 2590-2603 (2013
    • (2013) J. Clin. Invest , vol.123 , pp. 2590-2603
    • Van Hauwermeiren, F.1
  • 22
    • 2342567291 scopus 로고    scopus 로고
    • Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients
    • Matthews J.G., Ito K., Barnes P.J., & Adcock I.M. Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients. J. Allergy Clin. Immunol. 113, 1100-1108 (2004
    • (2004) J. Allergy Clin. Immunol , vol.113 , pp. 1100-1108
    • Matthews, J.G.1    Ito, K.2    Barnes, P.J.3    Adcock, I.M.4
  • 23
    • 25844515028 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
    • Zhou B.H., et al. Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat. Immunol. 6, 1047-1053 (2005
    • (2005) Nat. Immunol , vol.6 , pp. 1047-1053
    • Zhou, B.H.1
  • 24
    • 84896849811 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation
    • Kabata H., et al. Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation. Nat. Commun. 4, 2675 (2013
    • (2013) Nat. Commun , vol.4 , pp. 2675
    • Kabata, H.1
  • 25
    • 79953718767 scopus 로고    scopus 로고
    • Cytokine/anti-cytokine therapy -novel treatments for asthma?
    • Hansbro P.M., Kaiko G.E., & Foster P.S. Cytokine/anti-cytokine therapy -novel treatments for asthma?. Br. J. Pharmacol. 163, 81-95 (2011
    • (2011) Br. J. Pharmacol , vol.163 , pp. 81-95
    • Hansbro, P.M.1    Kaiko, G.E.2    Foster, P.S.3
  • 26
    • 58249118714 scopus 로고    scopus 로고
    • Where asthma and hypersensitivity pneumonitis meet and differ: Noneosinophilic severe asthma
    • Bogaert P., Tournoy K.G., Naessens T., & Grooten J. Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma. Am. J. Pathol. 174, 3-13 (2009
    • (2009) Am. J. Pathol , vol.174 , pp. 3-13
    • Bogaert, P.1    Tournoy, K.G.2    Naessens, T.3    Grooten, J.4
  • 27
    • 0028983633 scopus 로고
    • Tumor-necrosis-factor-alpha increases airway responsiveness and sputum neutrophilia in normal human-subjects
    • Thomas P.S., Yates D.H., & Barnes P.J. Tumor-necrosis-factor-alpha increases airway responsiveness and sputum neutrophilia in normal human-subjects. Am. J. Respir. Crit. Care Med. 152, 76-80 (1995
    • (1995) Am. J. Respir. Crit. Care Med , vol.152 , pp. 76-80
    • Thomas, P.S.1    Yates, D.H.2    Barnes, P.J.3
  • 28
    • 0026065788 scopus 로고
    • Recruitment of neutrophils during ige-dependent cutaneous late phase reactions in the mouse is mast cell-dependent -partial inhibition of the reaction with antiserum against tumor-necrosis-factor-alpha
    • Wershil B.K., Wang Z.S., Gordon J.R., & Galli S.J. Recruitment of neutrophils during ige-dependent cutaneous late phase reactions in the mouse is mast cell-dependent -partial inhibition of the reaction with antiserum against tumor-necrosis-factor-alpha. J. Clin. Investig. 87, 446-453 (1991
    • (1991) J. Clin. Investig , vol.87 , pp. 446-453
    • Wershil, B.K.1    Wang, Z.S.2    Gordon, J.R.3    Galli, S.J.4
  • 29
    • 55249088124 scopus 로고    scopus 로고
    • Steroid-resistant neutrophilic inflammation in a mouse model of an acute exacerbation of asthma
    • Ito K., et al. Steroid-resistant neutrophilic inflammation in a mouse model of an acute exacerbation of asthma. Am. J. Respir. Cell Mol. Biol. 39, 543-550 (2008
    • (2008) Am. J. Respir. Cell Mol. Biol , vol.39 , pp. 543-550
    • Ito, K.1
  • 30
    • 84904435841 scopus 로고    scopus 로고
    • The complex relationship between inflammation and lung function in severe asthma
    • Manni M.L., et al. The complex relationship between inflammation and lung function in severe asthma. Mucosal immunology 7, 1186-1198 (2007
    • (2007) Mucosal Immunology , vol.7 , pp. 1186-1198
    • Manni, M.L.1
  • 31
    • 84863724269 scopus 로고    scopus 로고
    • Strengthening of antitumor immune memory and prevention of thymic atrophy mediated by adenovirus expressing IL-12 and GM-CSF
    • Choi K.J., Zhang S.N., Choi I.K., Kim J.S., & Yun C.O. Strengthening of antitumor immune memory and prevention of thymic atrophy mediated by adenovirus expressing IL-12 and GM-CSF. Gene Therapy 19, 711-723 (2012
    • (2012) Gene Therapy , vol.19 , pp. 711-723
    • Choi, K.J.1    Zhang, S.N.2    Choi, I.K.3    Kim, J.S.4    Yun, C.O.5
  • 32
    • 0034533593 scopus 로고    scopus 로고
    • Modulation of allergic inflammation in mice deficient in TNF receptors
    • Rudmann D.G., et al. Modulation of allergic inflammation in mice deficient in TNF receptors. Am. J. Physiol. Lung Cell. Mol. Physiol. 279, L1047-L1057 (2000
    • (2000) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.279 , pp. L1047-L1057
    • Rudmann, D.G.1
  • 33
    • 84860390495 scopus 로고    scopus 로고
    • ChronicOVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling
    • Cho J.Y., Pham A., Rosenthal P., Miller M., Doherty T., & Broide D.H. ChronicOVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling. Int. Immunopharmacol. 11, 1038-1044 (2011
    • (2011) Int. Immunopharmacol , vol.11 , pp. 1038-1044
    • Cho, J.Y.1    Pham, A.2    Rosenthal, P.3    Miller, M.4    Doherty, T.5    Broide, D.H.6
  • 34
    • 77953913216 scopus 로고    scopus 로고
    • Increased serum IL-17 is an independent risk factor for severe asthma
    • Agache I., Ciobanu C., Agache C., & Anghel M. Increased serum IL-17 is an independent risk factor for severe asthma. Respir. Med. 104, 1131-1137 (2010
    • (2010) Respir. Med , vol.104 , pp. 1131-1137
    • Agache, I.1    Ciobanu, C.2    Agache, C.3    Anghel, M.4
  • 35
    • 34247401706 scopus 로고    scopus 로고
    • Mast cell-derived tnf can promote th17 cell-dependent neutrophil recruitment in ovalbuminchallenged otii mice
    • Nakae S., Suto H., Berry G.J., & Galli S.J. Mast cell-derived TNF can promote Th17 cell-dependent neutrophil recruitment in ovalbuminchallenged OTII mice. Blood 109, 3640-3648 (2007
    • (2007) Blood , vol.109 , pp. 3640-3648
    • Nakae, S.1    Suto, H.2    Berry, G.J.3    Galli, S.J.4
  • 36
    • 56149097181 scopus 로고    scopus 로고
    • T(H)17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice
    • McKinley L., et al. T(H)17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J. Immunol. 181, 4089-4097 (2008
    • (2008) J. Immunol , vol.181 , pp. 4089-4097
    • McKinley, L.1
  • 37
    • 0029278910 scopus 로고
    • Prominent neutrophilic inflammation in sputumfrom subjects with asthma exacerbation
    • Fahy J.V., Kim K.W., Liu J., & Boushey H.A. Prominent neutrophilic inflammation in sputumfrom subjects with asthma exacerbation. J. Allergy Clin. Immunol. 95, 843-852 (1995
    • (1995) J. Allergy Clin. Immunol , vol.95 , pp. 843-852
    • Fahy, J.V.1    Kim, K.W.2    Liu, J.3    Boushey, H.A.4
  • 38
    • 68049139146 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor expression in induced sputum and bronchial mucosa in asthma and copd
    • Saha S., et al. Granulocyte-macrophage colony-stimulating factor expression in induced sputum and bronchial mucosa in asthma and COPD. Thorax 64, 671-676 (2009
    • (2009) Thorax , vol.64 , pp. 671-676
    • Saha, S.1
  • 39
    • 84883233547 scopus 로고    scopus 로고
    • TNF-alpha-mediated bronchial barrier disruption and regulation by src-family kinase activation
    • Hardyman M.A., et al. TNF-alpha-mediated bronchial barrier disruption and regulation by src-family kinase activation. J. Allergy Clin. Immunol. 132, 665-675 (2013
    • (2013) J. Allergy Clin. Immunol , vol.132 , pp. 665-675
    • Hardyman, M.A.1
  • 40
    • 0345734195 scopus 로고    scopus 로고
    • Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucortcoids
    • Cundall M., Sun Y.C., Miranda C., Trudeau J.B., Barnes S., & Wenzel S.E. Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucortcoids. J. Allergy Clin. Immunol. 112, 1064-1071 (2003
    • (2003) J. Allergy Clin. Immunol , vol.112 , pp. 1064-1071
    • Cundall, M.1    Sun, Y.C.2    Miranda, C.3    Trudeau, J.B.4    Barnes, S.5    Wenzel, S.E.6
  • 41
    • 41449101856 scopus 로고    scopus 로고
    • Cytokines induce an early steroid resistance in airway smooth muscle cells
    • Tliba O., et al. Cytokines induce an early steroid resistance in airway smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 38, 463-472 (2008
    • (2008) Am. J. Respir. Cell Mol. Biol , vol.38 , pp. 463-472
    • Tliba, O.1
  • 42
    • 80052153018 scopus 로고    scopus 로고
    • Inflammatory stimuli inhibit glucocorticoid-dependent transactivation in human pulmonary epithelial cells: Rescue by long-acting beta(2)-adrenoceptor agonists
    • Rider C.F., King E.M., Holden N.S., Giembycz M.A., & Newton R. Inflammatory stimuli inhibit glucocorticoid-dependent transactivation in human pulmonary epithelial cells: rescue by long-acting beta(2)-adrenoceptor agonists. J. Pharmacol. Exp. Ther. 338, 860-869 (2011
    • (2011) J. Pharmacol. Exp. Ther , vol.338 , pp. 860-869
    • Rider, C.F.1    King, E.M.2    Holden, N.S.3    Giembycz, M.A.4    Newton, R.5
  • 43
    • 84881368948 scopus 로고    scopus 로고
    • Poly I: C and respiratory syncytial virus (RSV) inhibit glucocorticoid receptor (GR)-mediated transactivation in lung epithelial, but not monocytic; Cell lines
    • Marketon J.I.W., & Corry J. Poly I: C and respiratory syncytial virus (RSV) inhibit glucocorticoid receptor (GR)-mediated transactivation in lung epithelial, but not monocytic; cell lines. Virus Res. 176, 303-306 (2013
    • (2013) Virus Res , vol.176 , pp. 303-306
    • Marketon, J.I.W.1    Corry, J.2
  • 44
    • 84875040561 scopus 로고    scopus 로고
    • Glucocorticoid-induced leucine zipper (gilz) regulates testicular foxo1 activity and spermatogonial stem cell (ssc) function
    • Ngo D., et al. Glucocorticoid-induced leucine zipper (GILZ) regulates testicular FOXO1 activity and spermatogonial stem cell (SSC) function. PLoS One, 8 (2013
    • (2013) Plos One , vol.8
    • Ngo, D.1
  • 45
    • 20444365526 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of TH2-attracting chemokines and disease severity
    • Ying S., et al. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of TH2-attracting chemokines and disease severity. J. Immunol. 174, 8183-8190 (2005
    • (2005) J. Immunol , vol.174 , pp. 8183-8190
    • Ying, S.1
  • 46
    • 84865595858 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin: A promising therapeutic target for allergic diseases
    • Wang W.L., et al. Thymic stromal lymphopoietin: a promising therapeutic target for allergic diseases. Int Arch. Allergy Immunol. 160, 18-26 (2013
    • (2013) Int Arch. Allergy Immunol , vol.160 , pp. 18-26
    • Wang, W.L.1
  • 47
    • 79953781744 scopus 로고    scopus 로고
    • A soluble thymic stromal lymphopoietin (tslp) antagonist, tslpr-immunoglobulin, reduces the severity of allergic disease by regulating pulmonary dendritic cells
    • Zhang F., Huang G., Hu B., Song Y., & Shi Y. A soluble thymic stromal lymphopoietin (TSLP) antagonist, TSLPR-immunoglobulin, reduces the severity of allergic disease by regulating pulmonary dendritic cells. Clin. Exp. Immunol. 164, 256-264 (2011
    • (2011) Clin. Exp. Immunol , vol.164 , pp. 256-264
    • Zhang, F.1    Huang, G.2    Hu, B.3    Song, Y.4    Shi, Y.5
  • 48
    • 84893789481 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin enhances Th2/Th22 and reduces IL-17A in protease-allergen-induced airways inflammation
    • Togbe D., et al. Thymic stromal lymphopoietin enhances Th2/Th22 and reduces IL-17A in protease-allergen-induced airways inflammation. ISRN Allergy 2013, 971036 (2013
    • (2013) ISRN Allergy , vol.2013 , pp. 971036
    • Togbe, D.1
  • 49
    • 84866130874 scopus 로고    scopus 로고
    • Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of gm-csf and il-33
    • Willart M.A., et al. Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J. Exp. Med. 209, 1505-1517 (2012
    • (2012) J. Exp. Med , vol.209 , pp. 1505-1517
    • Willart, M.A.1
  • 51
    • 82555191081 scopus 로고    scopus 로고
    • Short ragweed pollen triggers allergic inflammation through toll-like receptor 4-dependent thymic stromal lymphopoietin/ox40 ligand/ox40 signaling pathways
    • Li D.Q., et al. Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways. J. Allergy Clin. Immunol. 128, e2 (2011
    • (2011) J. Allergy Clin. Immunol , vol.128 , pp. e2
    • Li, D.Q.1
  • 52
    • 79961137189 scopus 로고    scopus 로고
    • Carcinoma of the thyroid gland showing thymic-like elements: Hypofunctioning nodule accumulating (99m)tc-mibi and (18)f-fdg
    • Chen L., Chen X., Zhang H., Feng L., & Zhu R. Carcinoma of the thyroid gland showing thymic-like elements: hypofunctioning nodule accumulating (99m)Tc-MIBI and (18)F-FDG. Hellenic J. Nuclear Med. 14, 190-191 (2011
    • (2011) Hellenic J. Nuclear Med , vol.14 , pp. 190-191
    • Chen, L.1    Chen, X.2    Zhang, H.3    Feng, L.4    Zhu, R.5
  • 53
    • 84884793076 scopus 로고    scopus 로고
    • Comparison of TNF antagonism by etanercept and dexamethasone on airway epithelium and remodeling in an experimental model of asthma
    • Yilmaz O., et al. Comparison of TNF antagonism by etanercept and dexamethasone on airway epithelium and remodeling in an experimental model of asthma. Int. Immunopharmacol. 17, 768-773 (2013
    • (2013) Int. Immunopharmacol , vol.17 , pp. 768-773
    • Yilmaz, O.1
  • 54
    • 72249086339 scopus 로고    scopus 로고
    • Anti-tumour necrosis factor alpha therapy in patients with rheumatoid arthritis results in a significant and long-lasting decrease of concomitant glucocorticoid treatment
    • Naumann L., Huscher D., Detert J., Spengler M., Burmester G.R., & Buttgereit F. Anti-tumour necrosis factor alpha therapy in patients with rheumatoid arthritis results in a significant and long-lasting decrease of concomitant glucocorticoid treatment. Ann. Rheum. Dis. 68, 1934-1936 (2009
    • (2009) Ann. Rheum. Dis , vol.68 , pp. 1934-1936
    • Naumann, L.1    Huscher, D.2    Detert, J.3    Spengler, M.4    Burmester, G.R.5    Buttgereit, F.6
  • 55
    • 36749055911 scopus 로고    scopus 로고
    • Combination of dexamethasone and etanercept reduces secondary damage in experimental spinal cord trauma
    • Genovese T., et al. Combination of dexamethasone and etanercept reduces secondary damage in experimental spinal cord trauma. Neuroscience 150, 168-181 (2007
    • (2007) Neuroscience , vol.150 , pp. 168-181
    • Genovese, T.1
  • 56
    • 65849427529 scopus 로고    scopus 로고
    • Glucocorticoid resistance in inflammatory diseases
    • Barnes P.J., & Adcock I.M. Glucocorticoid resistance in inflammatory diseases. Lancet 373, 1905-1917 (2009
    • (2009) Lancet , vol.373 , pp. 1905-1917
    • Barnes, P.J.1    Adcock, I.M.2
  • 57
    • 0027327619 scopus 로고
    • Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
    • Rothe J., et al. Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 364, 798-802 (1993
    • (1993) Nature , vol.364 , pp. 798-802
    • Rothe, J.1
  • 58
    • 0035661260 scopus 로고    scopus 로고
    • The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma
    • Tanaka H., et al. The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma. Inflamm. Res. 50, 616-624 (2001
    • (2001) Inflamm. Res , vol.50 , pp. 616-624
    • Tanaka, H.1
  • 59
    • 33847143728 scopus 로고    scopus 로고
    • Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells
    • Hammad H., et al. Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J. Exp. Med. 204, 357-367 (2007
    • (2007) J. Exp. Med , vol.204 , pp. 357-367
    • Hammad, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.