Longitudinal study of cytokine expression, lipid profile and neuronal growth factors in human breast milk from term and preterm deliveries

Nutrients

Volumn 7, Issue 10, 2015, Pages 8577-8591

  Collado, Maria Carmen ^a   Santaella, Marina ^b   Mira Pascual, Laia ^a   Martínez Arias, Elena ^c   Khodayar Pardo, Parisá ^c   Ros, Gaspar ^b   Martínez Costa, Cecilia ^c  

^a INSTITUTO DE AGROQUÍMICA Y TECNOLOGÍA DE ALIMENTOS CSIC   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Breast milk; Breastfeeding; Cytokines; Docosahexaenoic acid; Fatty acids; Growth factors; Human milk; Neurotrophic factor; Polyunsaturated fatty acids

Indexed keywords

ANGIOGENIN; COLONY STIMULATING FACTOR 1; CYTOKINE; DOCOSAHEXAENOIC ACID; EPIDERMAL GROWTH FACTOR; INTERLEUKIN 6; LIPID; MONOCYTE CHEMOTACTIC PROTEIN 1; NERVE GROWTH FACTOR; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID;

ADULT; ARTICLE; BREAST MILK; FATTY ACID ANALYSIS; FEMALE; GAS CHROMATOGRAPHY; GESTATIONAL AGE; HUMAN; NORMAL HUMAN; PREMATURE LABOR; PROSPECTIVE STUDY; PROTEIN EXPRESSION; PROTEIN MICROARRAY; BREAST FEEDING; LACTATION; METABOLISM; NEWBORN; PREGNANCY; PREMATURITY;

ADULT; BREAST FEEDING; CYTOKINES; FATTY ACIDS, OMEGA-3; FEMALE; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; LACTATION; MILK, HUMAN; NERVE GROWTH FACTORS; PREGNANCY;

EID: 84944937316     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu7105415     Document Type: Article

References (34)

1. Walker, A. Breast milk as the gold standard for protective nutrients. J. Pediatr. 2010, 156, S3-S7. [CrossRef] [PubMed]
2. Lönnerdal, B. Bioactive proteins in human milk: Mechanisms of action. J. Pediatr. 2010, 156, S26-S30. [CrossRef] [PubMed]
3. Lawrence, R.A.; Lawrence, R.M. Host-resistance factors and immunologic significance of human milk. In Breastfeeding: A Guide for Medical Profession, 7th ed.; Lawrence, R.A., Lawrence, R.M., Eds.; Elsevier: Mosby, MO, USA, 2011; pp. 153-195.
4. Garofalo, R. Cytokines in human milk. J. Pediatr. 2010, 156, S36-S40. [CrossRef] [PubMed]
5. Gregory, K.E.; Walker, W.A. Immunologic factors in human milk and disease prevention in the preterm Infant. Curr. Pediatr. Rep. 2013, 1, 222-228. [CrossRef] [PubMed]
6. Goldman, A.S.; Chheda, S.; Garofalo, R.; Schmalstieg, F.C. Cytokines in human milk: Properties and potential effects upon the mammary gland and the neonate. J. Mammary Gland Biol. Neoplasia 1996, 1, 251-258. [CrossRef] [PubMed]
7. Srivastava, M.D.; Srivastava, A.; Brouhard, B.; Saneto, R.; Groh-Warg, S.; Kubit, J. Cytokines in human milk. Res. Commun. Mol. Pathol. Pharmacol. 1996, 93, 263-287. [PubMed]
8. Kverka, M.; Burianova, J.; Lodinova-Zadnikova, R.; Kocourkova, I.; Cinova, J.; Tuckova, L.; Tlaskalova-Hogenova, H. Cytokine profiling in human colostrum and milk by protein array. Clin. Chem. 2007, 53, 955-962. [CrossRef] [PubMed]
9. Hawkes, J.S.; Bryan, D.L.; James, M.J.; Gibson, R.A. Cytokines (IL-1β, IL-6, TNF-α, TGF-β1, and TGF-β2) and prostaglandin E2 in human milk during the first three months postpartum. Pediatr. Res. 1999, 46, 194-199. [CrossRef] [PubMed]
10. Groer, M.; Duffy, A.; Morse, S.; Kane, B.; Zaritt, J.; Roberts, S.; Ashmeade, T. Cytokines, chemokines, and growth factors in banked human donor milk for preterm infants. J. Hum. Lact. 2014, 24, 317-323. [CrossRef] [PubMed]
11. Dangat, K.; Kilari, A.; Mehendale, S.; Lalwani, S.; Joshi, S. Higher levels of brain derived neurotrophic factor but similar nerve growth factor in human milk in women with preeclampsia. Int. J. Dev. Neurosci. 2013, 31, 209-213. [CrossRef] [PubMed]
12. Chalazonitis, A.; Pham, T.D.; Rothman, T.P.; DiStefano, P.S.; Bothwell, M.; Blair-Flynn, J.; Tesarollo, L.; Gershon, M.D. Neurotrophin-3 is required for the survival-differentiation of subsets of developing enteric neurons. J. Neurosci. 2001, 21, 5620-5636. [PubMed]
13. Brenna, J.T.; Varamini, B.; Jensen, R.G.; Diersen-Schade, D.A.; Boettcher, J.A.; Arterburn, L.M. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am. J. Clin. Nutr. 2007, 85, 1457-1464. [PubMed]
14. Helland, I.B.; Smith, L.; Saarem, K.; Saugstad, O.D.; Drevon, C.A. Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age. Pediatrics 2003, 111, e39-e44. [CrossRef] [PubMed]
15. Lucas, A.; Morley, R.; Cole, T.J.; Gore, S.M. A randomised multicentre study of human milk versus formula and later development in preterm infants. Arch. Dis. Child. 1994, 70, F141-F146. [CrossRef]
16. Horwood, L.J.; Fergusson, D.M. Breastfeeding and later cognitive and academic outcomes. Pediatrics 1998, 101, E9. [CrossRef] [PubMed]
17. Daniels, M.C.; Adair, L.S. Breast-feeding influences cognitive development in Filipino children. J. Nutr. 2005, 135, 2589-2595. [PubMed]
18. Koletzko, B.; Cetin, I.; Brenna, J.T.; Perinatal Lipid Intake Working Group; Child Health Foundation; Diabetic Pregnancy Study Group; European Association of Perinatal Medicine; European Society for Clinical Nutrition and Metabolism; European Society for Paediatric Gastroenterology, Hepatology and Nutrition, Committee on Nutrition. Dietary fat intakes for pregnant and lactating women. Br. J. Nutr. 2007, 98, 873-875. [PubMed]
19. Khodayar-Pardo, P.; Mira-Pascual, L.; Collado, M.C.; Martínez-Costa, C. Impact of lactation stage, gestational age and mode of delivery on breast milk microbiota. J. Perinatol. 2014, 34, 599-605. [CrossRef] [PubMed]
20. Carlson, S.J.; Fallon, E.M.; Kalish, B.T.; Gura, K.M.; Puder, M. The role of the !-3 fatty acid DHA in the human cycle life. J. Parenter. Enteral Nutr. 2013, 37, 15-22. [CrossRef] [PubMed]
21. Hadders-Algra, M. Effect of long-chain polyunsaturated fatty acid supplementation on neurodevelopmental outcome in full-term infants. Nutrients 2010, 2, 790-804. [CrossRef] [PubMed]
22. Lawrence, R.A.; Lawrence, R.M. Biochemistry of human milk. In Breastfeeding: A Guide for Medical Profession, 7th ed.; Lawrence, R.A., Lawrence, R.M., Eds.; Elsevier: Mosby, MO, USA, 2011; pp. 98-152.
23. López-López, A.; López-Sabater, M.C.; Campoy-Folgoso, C.; Rivero-Urgell, M.; Castellote-Bargalló, A.I. Fatty acid and sn-2 fatty acid composition in human milk from Granada (Spain) and in infant formulas. Eur. J. Clin. Nutr. 2002, 56, 1242-1254. [CrossRef] [PubMed]
24. Yuhas, R.; Pramuk, K.; Lien, E.L. Human milk fatty acid composition from nine countries varies most in DHA. Lipids 2006, 41, 851-858. [CrossRef] [PubMed]
25. Mihályi, K.; Györei, E.; Szabó, É.; Marosvölgyi, T.; Lohner, S.; Decsi, T. Contribution of n-3 long-chain polyunsaturated fatty acids to human milk is still low in Hungarian mothers. Eur. J. Peditar. 2015, 174, 393-398. [CrossRef] [PubMed]
26. Krauss-Etschmann, S.; Shadid, R.; Campoy, C.; Hoster, E.; Demmelmair, H.; Jiménez, M.; Gil, A.; Rivero, M.; Veszprémi, B.; Decsi, T.; et al. Effects of fish-oil and folate supplementation of pregnant women on maternal and fetal plasma concentrations of docosahexaenoic acid and eicosapentaenoic acid: A European randomized multicenter trial. Am. J. Clin. Nutr. 2007, 85, 1392-1400. [PubMed]
27. Martin, M.A.; Lassek, W.D.; Gaulin, S.J.; Evans, R.W.; Woo, J.G.; Geraghty, S.R.; Davidson, B.S.; Morrow, A.L.; Kaplan, H.S.; Gurven, M.D. Fatty acid composition in the mature milk of Bolivian forager-horticulturalists: Controlled comparisons with a US sample. Matern. Child Nutr. 2012, 8, 404-418. [CrossRef] [PubMed]
28. Granot, E.; Ishay-Gigi, K.; Malaach, L.; Flidel-Rimon, O. Is there a difference in breast milk fatty acid composition of mothers of preterm and term infants? J. Matern. Fetal Neonatal Med. 2015, 10, 1-18. [CrossRef] [PubMed]
29. Shi, Y.; Liu, C.H.; Roberts, A.I.; Das, J.; Xu, G.; Ren, G.; Zhang, Y.; Zhang, L.; Yuan, Z.R.; Tan, H.S.; et al. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: What we do and don't know. Cell Res. 2006, 16, 126-133. [CrossRef] [PubMed]
30. Brandtzaeg, P. Mucosal immunity: Integration between mother and the breast-fed infant. Vaccine 2003, 21, 3382-3388. [CrossRef]
31. Dvorak, B.; Fituch, C.C.;Williams, C.S.; Hurst, N.M.; Schanler, R.J. Increased epidermal growth factor levels in human milk of mothers with extremely premature infants. Pediatr. Res. 2003, 54, 15-19. [CrossRef] [PubMed]
32. Erickson, J.E.; Brosenitsch, T.A.; Katz, D.M. Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor are required simultaneously for survival of dopaminergic primary sensory neurons in vivo. J. Neurosci. 2001, 21, 581-589. [PubMed]
33. Frost, B.L.; Jilling, T.; Lapin, B.; Maheshwari, A.; Caplan, M.S. Maternal breast milk transforming growth factor-β and feeding intolerance in preterm infants. Pediatr. Res. 2014, 76, 386-389. [CrossRef] [PubMed]
34. Fichter, M.; Klotz, M.; Hirschberg, D.L.;Waldura, B.; Schofer, O.; Ehnert, S.; Schwarz, L.K.; van Ginneken, C.; Schäfer, K.K. Breast milk contains relevant neurotrophic factors and cytokines for enteric nervous system development. Mol. Nutr. Food Res. 2011, 55, 1592-1596. [CrossRef] [PubMed]