Paracetamol as a post prandial marker for gastric emptying, a food-drug interaction on absorption

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Bartholome R ^a   Salden, B ^b   Vrolijk, M F ^a   Troost, F J ^b   Masclee, A ^b   Bast, A ^a   Haenen, G R ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PARACETAMOL;

ADULT; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BLOOD LEVEL; DUODENUM; ENCAPSULATION; FEMALE; FOOD DRUG INTERACTION; FRACTIONATION; HUMAN; HUMAN EXPERIMENT; MALE; MAXIMUM PLASMA CONCENTRATION; MEAL; NORMAL HUMAN; PLASMA CONCENTRATION-TIME CURVE; RANDOMIZED CONTROLLED TRIAL; STOMACH; STOMACH ABSORPTION; STOMACH CONTENT; STOMACH EMPTYING; ADOLESCENT; PHYSIOLOGY; POSTPRANDIAL STATE; YOUNG ADULT;

ACETAMINOPHEN; ADOLESCENT; ADULT; CROSS-OVER STUDIES; FEMALE; FOOD-DRUG INTERACTIONS; GASTRIC EMPTYING; HUMANS; MALE; POSTPRANDIAL PERIOD; YOUNG ADULT;

EID: 84944810507     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0136618     Document Type: Article

References (14)

1. Henderson HRJRRFG. Rang & Dale's Pharmacology. 7 ed: Churchill Livingstone; 2011 March 2011. 792 p.
2. Hunt JN. A possible relation between the regulation of gastric emptying and food intake. Am J Physiol. 1980; 239(1):G1-4. Epub 1980/07/01. PMID: 7395999.
3. Cvijic S, Parojcic J, Langguth P. Viscosity-mediated negative food effect on oral absorption of poorlypermeable drugs with an absorption window in the proximal intestine: In vitro experimental simulation and computational verification. Eur J Pharm Sci. 2014. Epub 2014/04/23. doi: 10.1016/j.ejps.2014.04. 008 PMID: 24751672.
4. Parojcic J, Vasiljevic D, Ibric S, Djuric Z. Tablet disintegration and drug dissolution in viscous media: paracetamol IR tablets. Int J Pharm. 2008; 355(1-2):93-9. Epub 2008/01/30. doi: 10.1016/j.ijpharm. 2007.11.058 PMID: 18226480.
5. Welling PG. Effects of food on drug absorption. Annu Rev Nutr. 1996; 16:383-415. Epub 1996/01/01. doi: 10.1146/annurev.nu.16.070196.002123 PMID: 8839932.
6. Willems M, Quartero AO, Numans ME. How useful is paracetamol absorption as a marker of gastric emptying? A systematic literature study. Dig Dis Sci. 2001; 46(10):2256-62. Epub 2001/10/30. PMID: 11680606.
7. Medhus AW, Lofthus CM, Bredesen J, Husebye E. Gastric emptying: the validity of the paracetamol absorption test adjusted for individual pharmacokinetics. Neurogastroenterol Motil. 2001; 13(3):179-85. Epub 2001/07/05. PMID: 11437980.
8. Di Pietra AM, Gatti R, Andrisano V, Cavrini V. Application of high-performance liquid chromatography with diode-array detection and on-line post-column photochemical derivatization to the determination of analgesics. J Chromatogr A. 1996; 729(1-2):355-61. Epub 1996/04/05. PMID: 9004960.
9. Viswanathan CT, Bansal S, Booth B, DeStefano AJ, Rose MJ, Sailstad J, et al. Quantitative bioanalytical methods validation and implementation: best practices for chromatographic and ligand binding assays. Pharm Res. 2007; 24(10):1962-73. Epub 2007/04/27. doi: 10.1007/s11095-007-9291-7 PMID: 17458684.
10. Heading RC, Nimmo J, Prescott LF, Tothill P. The dependence of paracetamol absorption on the rate of gastric emptying. Br J Pharmacol. 1973; 47(2):415-21. Epub 1973/02/01. PMID: 4722050; PubMed Central PMCID: PMC1776534.
11. Lentz KA. Current methods for predicting human food effect. Aaps J. 2008; 10(2):282-8. Epub 2008/ 05/27. doi: 10.1208/s12248-008-9025-8 PMID: 18500565; PubMed Central PMCID: PMC2751375.
12. Holt S, Heading RC, Carter DC, Prescott LF, Tothill P. Effect of gel fibre on gastric emptying and absorption of glucose and paracetamol. Lancet. 1979; 1(8117):636-9. Epub 1979/03/24. PMID: 85872.
13. Mateo Anson N, Aura AM, Selinheimo E, Mattila I, Poutanen K, van den Berg R, et al. Bioprocessing of wheat bran in whole wheat bread increases the bioavailability of phenolic acids in men and exerts antiinflammatory effects ex vivo. J Nutr. 2011; 141(1):137-43. Epub 2010/11/26. doi: 10.3945/jn.110. 127720 PMID: 21106920.
14. Gonzalez A, Mugueta C, Parra D, Labayen I, Martinez A, Varo N, et al. Characterisation with stable isotopes of the presence of a lag phase in the gastric emptying of liquids. Eur J Nutr. 2000; 39(5):224-8. Epub 2000/12/29. PMID: 11131369.