A non-signaling role of robo2 in tendons is essential for slit processing and muscle patterning

Development (Cambridge)

Volumn 142, Issue 20, 2015, Pages 3512-3518

  Ordan, Elly ^a   Volk, Talila ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Drosophila embryo; Muscle; Robo; Slit; Slit cleavage

Indexed keywords

MUTANT PROTEIN; OLIGOMER; ROUNDABOUT RECEPTOR; SLIT PROTEIN; SLIT RECEPTOR ROUNDABOUT 1; SLIT RECEPTOR ROUNDABOUT 2; SLIT RECEPTOR ROUNDABOUT 3; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; IMMUNOGLOBULIN RECEPTOR; LEA PROTEIN, DROSOPHILA; NERVE PROTEIN; SLI PROTEIN, DROSOPHILA;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ELONGATION; CELL MEMBRANE; CONTROLLED STUDY; DROSOPHILA; ECTODERM; EMBRYO; GENE INTERACTION; MUSCLE CELL; MUSCLE DEVELOPMENT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TENDON; ANIMAL; DROSOPHILA MELANOGASTER; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; HETEROZYGOTE; HOMOZYGOTE; MORPHOGENESIS; MUSCLE; MUTATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; RNA INTERFERENCE;

ANIMALS; BODY PATTERNING; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCK-IN TECHNIQUES; HETEROZYGOTE; HOMOZYGOTE; MUSCLES; MUTATION; NERVE TISSUE PROTEINS; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IMMUNOLOGIC; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TENDONS;

EID: 84944790057     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.128157     Document Type: Article

References (20)

1. Ashburner, M., Golic, K. G. and Hawley, R. S. (2005). Drosophila: A Laboratory Handbook, 2nd edn. Cold Spring Harbor, N.Y: Cold Spring Harbor Laboratory Press.
2. Brose, K., Bland, K. S., Wang, K. H., Arnott, D., Henzel, W., Goodman, C. S., Tessier-Lavigne, M. and Kidd, T. (1999). Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell 96, 795-806.
3. Coleman, H. A., Labrador, J.-P., Chance, R. K. and Bashaw, G. J. (2010). The Adam family metalloprotease Kuzbanian regulates the cleavage of the roundabout receptor to control axon repulsion at the midline. Development 137, 2417-2426.
4. Dubois, L., Enriquez, J., Daburon, V., Crozet, F., Lebreton, G., Crozatier, M. and Vincent, A. (2007). Collier transcription in a single Drosophila muscle lineage: the combinatorial control of muscle identity. Development 134, 4347-4355.
5. Enriquez, J., de Taffin, M., Crozatier, M., Vincent, A. and Dubois, L. (2012). Combinatorial coding of Drosophila muscle shape by Collier and Nautilus. Dev. Biol. 363, 27-39.
6. Evans, T. A. and Bashaw, G. J. (2010). Functional diversity of Robo receptor immunoglobulin domains promotes distinct axon guidance decisions. Curr. Biol. 20, 567-572.
7. Evans, T. A., Santiago, C., Arbeille, E. and Bashaw, G. J. (2015). Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons. eLife 4, e08407.
8. Folker, E. S., Schulman, V. K. and Baylies, M. K. (2012). Muscle length and myonuclear position are independently regulated by distinct Dynein pathways. Development 139, 3827-3837.
9. Folker, E. S., Schulman, V. K. and Baylies, M. K. (2014). Translocating myonuclei have distinct leading and lagging edges that require kinesin and dynein. Development 141, 355-366.
10. Kramer, S. G., Kidd, T., Simpson, J. H. and Goodman, C. S. (2001). Switching repulsion to attraction: changing responses to slit during transition in mesoderm migration. Science 292, 737-740.
11. Kraut, R. and Zinn, K. (2004). Roundabout 2 regulates migration of sensory neurons by signaling in trans. Curr. Biol. 14, 1319-1329.
12. Ordan, E., Brankatschk, M., Dickson, B., Schnorrer, F. and Volk, T. (2015). Slit cleavage is essential for producing an active, stable, non-diffusible short-range signal that guides muscle migration. Development 142, 1431-1436.
13. Schejter, E. D. and Baylies, M. K. (2010). Born to run: creating the muscle fiber. Curr. Opin. Cell Biol. 22, 566-574.
14. Schnorrer, F. and Dickson, B. J. (2004). Muscle building; mechanisms of myotube guidance and attachment site selection. Dev. Cell 7, 9-20.
15. Schweitzer, R., Zelzer, E. and Volk, T. (2010). Connecting muscles to tendons: tendons and musculoskeletal development in flies and vertebrates. Development 137, 2807-2817.
16. Seiradake, E., von Philipsborn, A. C., Henry, M., Fritz, M., Lortat-Jacob, H., Jamin, M., Hemrika, W., Bastmeyer, M., Cusack, S. and McCarthy, A. A. (2009). Structure and functional relevance of the Slit2 homodimerization domain. EMBO Rep. 10, 736-741.
17. Spitzweck, B., Brankatschk, M. and Dickson, B. J. (2010). Distinct protein domains and expression patterns confer divergent axon guidance functions for Drosophila Robo receptors. Cell 140, 409-420.
18. Volk, T. (1999). Singling out Drosophila tendon cells: a dialogue between two distinct cell types. Trends Genet. 15, 448-453.
19. Wang, K. H., Brose, K., Arnott, D., Kidd, T., Goodman, C. S., Henzel, W. and Tessier-Lavigne, M. (1999). Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching. Cell 96, 771-784.
20. Wayburn, B. and Volk, T. (2009). LRT, a tendon-specific leucine-rich repeat protein, promotes muscle-tendon targeting through its interaction with Robo. Development 136, 3607-3615.