Enhanced bone healing using collagen-hydroxyapatite scaffold implantation in the treatment of a large multiloculated mandibular aneurysmal bone cyst in a thoroughbred filly

Journal of Tissue Engineering and Regenerative Medicine

Volumn 9, Issue 10, 2015, Pages 1193-1199

  David, Florent ^a,b   Levingstone, Tanya J ^c,d   Schneeweiss, Wilfried ^a,e   de Swarte, Marie ^a   Jahns, Hanne ^a   Gleeson, John P ^c,d,f   O'Brien, Fergal J ^c,d  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b Mid Atlantic Equine Medical Center   (United States)

^c ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^d TRINITY COLLEGE DUBLIN   (Ireland)

^e Pferdeklinik Pegasus   (Austria)

^f DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

Bone graft substitute; Collagen based scaffolds; Computed tomography; Equine; Mandibular aneurysmal bone cyst; Tissue engineering

Indexed keywords

BIOCOMPATIBILITY; BONE; COLLAGEN; COMPUTERIZED TOMOGRAPHY; REPAIR; SCAFFOLDS (BIOLOGY);

BONE GRAFT SUBSTITUTES; BONE HEALING; CLINICAL TREATMENTS; COLLAGEN-BASED SCAFFOLDS; EQUINE; IN-VIVO; MANDIBULAR ANEURYSMAL BONE CYST; MANDIBULAR BONE; OSTEOGENESIS; TISSUES ENGINEERINGS;

HYDROXYAPATITE;

COLLAGEN; COLLAGEN HYDROXYAPATITE SCAFFOLD; HYDROXYAPATITE; MOLECULAR SCAFFOLD; UNCLASSIFIED DRUG;

ANEURYSMAL BONE CYST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEMINERALIZATION; BONE REMODELING; BONE SWELLING; BRAIN CORTEX; CELL PROLIFERATION; COMPUTER ASSISTED TOMOGRAPHY; CORTICAL THICKNESS (BONE); CRANIOMAXILLOFACIAL; FEMALE; FOLLOW UP; FRACTURE HEALING; IMPLANTATION; MEDULLA OBLONGATA; MULTILOCULATED MANDIBULAR ANEURYSMAL BONE CYST; NANOFABRICATION; NONHUMAN; OSTEOCLAST; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SURGICAL TECHNIQUE; TREATMENT DURATION; TREATMENT RESPONSE; ANIMAL; BONE; BONE CYSTS, ANEURYSMAL; BONE TRANSPLANTATION; HORSE; HORSE DISEASES; MANDIBULAR DISEASES; PATHOLOGY; PATHOPHYSIOLOGY; RADIOGRAPHY; TISSUE SCAFFOLD; VETERINARY;

ANIMALS; BONE AND BONES; BONE CYSTS, ANEURYSMAL; BONE TRANSPLANTATION; COLLAGEN; DURAPATITE; FEMALE; HORSE DISEASES; HORSES; MANDIBULAR DISEASES; TISSUE SCAFFOLDS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84944511825     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.2006     Document Type: Article

References (26)

1. Baxter GM, Turner SA. 2002; Diseases of bone and related structures. In Adams' Lameness in Horses, 5th edn, Stashak ST (ed). Lippincott, Williams & Wilkins: Baltimore, MD; 433-434.
2. Boden SD, Zdeblick TA, Sandhu HS et al. 2000; The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: a preliminary report. Spine 25: 376-381.
3. Bryant U, Fallon L, Lee M et al. 2012; Congenital aneurysmal bone cyst in a foal. J Equine Vet Sci 32: 320-323.
4. Carroll CL, Huntington PJ. 1988; Body condition scoring and weight estimation of horses. Equine Vet J 20: 41-45.
5. Cottalorda J, Kohler R, de Gauzy JS et al. 2004; Epidemiology of aneurysmal bone cyst in children: a multicenter study and literature review. J Pediatr Orthop 13: 389-394.
6. FDA. 2002; InFUSE™ Bone Graft/LT-CAGE™ Lumbar Tapered Fusion Device - P000058. US Food and Drug Administration: http://www.accessdata.fda.gov/cdrh_docs/pdf/P000058a.pdf (accessed 2 September 2014).
7. FDA. 2001; OP-1™ - H010002. US Food and Drug Administration: http://www.accessdata.fda.gov/cdrh_docs/pdf/h010002a.pdf (accessed 2 September 2014).
8. Garrett MP, Kakarla UK, Porter RW et al. 2010; Formation of painful seroma and edema after the use of recombinant human bone morphogenetic protein-2 in posterolateral lumbar spine fusions. Neurosurgery 66: 1044-1049.
9. Gleeson JP, Plunkett NA, O'Brien FJ. 2010; Addition of hydroxyapatite improves stiffness, interconnectivity and osteogenic potential of a highly porous collagen-based scaffold for bone tissue regeneration. Eur Cell Mater 20: 218-230.
10. Jaffe JL, Lichtenstein L. 1942; Solitary unicameral bone cyst with emphasis on the Roentgen picture. Arch Surg 44: 1004-1025.
11. Leithner A, Machacek F, Haas OA et al. 2004; J Pediatr Orthop B 13: 214-217.
12. Lichtenstein L. 1957; Aneurysmal bone cyst: observations on 50 cases. J Bone Joint Surg Am 3: 837-882.
13. Lyons F, Gleeson JP, Partap S et al. 2014; Novel micro-hydroxyapatite particles in a collagen scaffold: a bioactive bone void filler? Clin Orthop Relat Res 472: 1318-13128.
14. McKay B, Sandhu HS. 2002; Use of recombinant human bone morphogenetic protein-2 in spinal fusion applications. Spine 27: S66-85.
15. Murphy CM, Schindeler A, Gleeson JP et al. 2014; A collagen-hydroxyapatite scaffold allows for binding and co-delivery of recombinant bone morphogenetic proteins and bisphosphonates. Acta Biomater 10: 2250-2258.
16. O'Brien FJ, Plunkett NA, Gleeson JP. 2007; A collagen/hydroxyapatite composite scaffold, and process for the production thereof. US Patent No. 8435552, WO Patent No. 2008096334A2.
17. Ordidge R. 2001; Pathological fracture of the radius secondary to an aneurysmal bone cyst in a horse. Eq Vet Educ 13: 239-242.
18. Sciadini MF, Johnson KD. 2000; Evaluation of recombinant human bone morphogenetic protein-2 as a bone-graft substitute in a canine segmental defect model. J Orthop Res 18: 289-302.
19. Services DoHaH. 2010; Bone morphogenetic protein: the state of the evidence of on-label and off-label use: www.hhs.gov; available from: http://www.cms.gov/DeterminationProcess/downloads/id75ta.pdf?bcsi_scan_9CF786ACA806128D=0&bcsi_scan_filename=id75ta.pdf (accessed 2 September 2014).
20. Shields LB, Raque GH, Glassman SD et al. 2006; Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion. Spine 31: 542-547.
21. Szpalski C, Wetterau M, Barr J et al. 2012; Bone tissue engineering: current strategies and techniques - Part I: Scaffolds. Tissue Eng B 18: 246-257.
22. Thompson KG. 2007; Diseases of bones. In Jubb, Kennedy, and Palmer's Pathology of Domestic Animals, 5th edn, Maxie MG (ed). Saunders: Philadelphia, PA; 129.
23. Vaidya R. 2009; Transforaminal interbody fusion and the 'off label' use of recombinant human bone morphogenetic protein-2. Spine J 9: 667-669.
24. Wong DA, Kumar A, Jatana S et al. 2008; Neurologic impairment from ectopic bone in the lumbar canal: a potential complication of off-label PLIF/TLIF use of bone morphogenetic protein-2 (BMP-2). Spine J 8: 1011-1018.
25. Wu Z, Yang X, Xiao J et al. 2011; Aneurysmal bone cyst secondary to giant cell tumor of the mobile spine: a report of 11 cases. Spine 36: 1385-1390.
26. Yasko AW, Lane JM, Fellinger EJ et al. 1992; The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats. J Bone Joint Surg Am 74: 659-670.