Multi-modal imaging with a toolbox of influenza a reporter viruses

Viruses

Volumn 7, Issue 10, 2015, Pages 5319-5327

  Tran, Vy ^a   Poole, Daniel S ^a   Jeffery, Justin J ^b   Sheahan, Timothy P ^c   Creech, Donald ^c   Yevtodiyenko, Aleksey ^d   Peat, Andrew J ^c   Francis, Kevin P ^d   You, Shihyun ^c   Mehle, Andrew ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

^c GLAXOSMITHKLINE   (United States)

^d PERKINELMER INC   (United States)

Author keywords

Influenza virus; Multi modal imaging; Multiplicity reactivation; Reporter virus

Indexed keywords

ANTIVIRUS AGENT;

ANIMAL; BAGG ALBINO MOUSE; DISEASE MODEL; FEMALE; FLUORESCENCE IMAGING; GROWTH, DEVELOPMENT AND AGING; INFLUENZA A VIRUS; LUMINESCENCE; MULTIMODAL IMAGING; ORTHOMYXOVIRIDAE INFECTIONS; PATHOLOGY; PROCEDURES; REPORTER GENE; STAINING; TREATMENT OUTCOME; VIROLOGY; VIRUS LOAD; WHOLE BODY IMAGING;

ANIMALS; ANTIVIRAL AGENTS; DISEASE MODELS, ANIMAL; FEMALE; GENES, REPORTER; INFLUENZA A VIRUS; LUMINESCENT MEASUREMENTS; MICE, INBRED BALB C; MULTIMODAL IMAGING; OPTICAL IMAGING; ORTHOMYXOVIRIDAE INFECTIONS; STAINING AND LABELING; TREATMENT OUTCOME; VIRAL LOAD; WHOLE BODY IMAGING;

EID: 84944463422     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v7102873     Document Type: Article

References (25)

1. Tran, V.; Moser, L.A.; Poole, D.S.; Mehle, A. Highly sensitive real-time in vivo imaging of an influenza reporter virus reveals dynamics of replication and spread. J. Virol. 2013, 87, 13321–13329. [CrossRef] [PubMed]
2. Karlsson, E.A.; Meliopoulos, V.A.; Savage, C.; Livingston, B.; Mehle, A.; Schultz-Cherry, S. Visualizing real-time influenza virus infection, transmission and protection in ferrets. Nat. Commun. 2015, 6, 6378. [CrossRef] [PubMed]
3. Ozawa, M.; Victor, S.T.; Taft, A.S.; Yamada, S.; Li, C.; Hatta, M.; Das, S.C.; Takashita, E.; Kakugawa, S.; Maher, E.A.; et al. Replication-incompetent influenza A viruses that stably express a foreign gene. J. Gen. Virol. 2011, 92, 2879–2888. [CrossRef] [PubMed]
4. Manicassamy, B.; Manicassamy, S.; Belicha-Villanueva, A.; Pisanelli, G.; Pulendran, B.; Garcia-Sastre, A. Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus. Proc. Natl. Acad. Sci. USA 2010, 107, 11531–11536. [CrossRef] [PubMed]
5. Martinez-Sobrido, L.; Cadagan, R.; Steel, J.; Basler, C.F.; Palese, P.; Moran, T.M.; Garcia-Sastre, A. Hemagglutinin-pseudotyped green fluorescent protein-expressing influenza viruses for the detection of influenza virus neutralizing antibodies. J. Virol. 2010, 84, 2157–2163. [CrossRef] [PubMed]
6. Heaton, N.S.; Leyva-Grado, V.H.; Tan, G.S.; Eggink, D.; Hai, R.; Palese, P. In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies. J. Virol. 2013, 87, 8272–8281. [CrossRef] [PubMed]
7. Pan, W.; Dong, Z.; Li, F.; Meng, W.; Feng, L.; Niu, X.; Li, C.; Luo, Q.; Li, Z.; Sun, C.; et al. Visualizing influenza virus infection in living mice. Nat. Commun. 2013, 4, 2369. [CrossRef] [PubMed]
8. Lakdawala, S.S.; Wu, Y.; Wawrzusin, P.; Kabat, J.; Broadbent, A.J.; Lamirande, E.W.; Fodor, E.; Altan-Bonnet, N.; Shroff, H.; Subbarao, K. Influenza A Virus Assembly Intermediates Fuse in the Cytoplasm. PLoS Pathog. 2014, 10, e1003971. [CrossRef] [PubMed]
9. Fukuyama, S.; Katsura, H.; Zhao, D.; Ozawa, M.; Ando, T.; Shoemaker, J.E.; Ishikawa, I.; Yamada, S.; Neumann, G.; Watanabe, S.; et al. Multi-spectral fluorescent reporter influenza viruses (Color-flu) as powerful tools for in vivo studies. Nat. Commun. 2015, 6, 6600. [CrossRef] [PubMed]
10. Nogales, A.; Baker, S.F.; Martinez-Sobrido, L. Replication-competent influenza A viruses expressing a red fluorescent protein. Virology 2015, 476, 206–216. [CrossRef] [PubMed]
11. Eckert, N.; Wrensch, F.; Gartner, S.; Palanisamy, N.; Goedecke, U.; Jager, N.; Pohlmann, S.; Winkler, M. Influenza A virus encoding secreted Gaussia luciferase as useful tool to analyze viral replication and its inhibition by antiviral compounds and cellular proteins. PLoS ONE 2014, 9, e97695. [CrossRef] [PubMed]
12. Sutton, T.C.; Obadan, A.; Lavigne, J.; Chen, H.; Li, W.; Perez, D.R. Genome rearrangement of influenza virus for anti-viral drug screening. Virus Res. 2014, 189, 14–23. [CrossRef] [PubMed]
13. Li, F.; Feng, L.; Pan, W.; Dong, Z.; Li, C.; Sun, C.; Chen, L. Generation of Replication-Competent Recombinant Influenza A Viruses Carrying a Reporter Gene Harbored in the Neuraminidase Segment. Journal of Virology 2010, 84, 12075–12081. [CrossRef] [PubMed]
14. Pena, L.; Sutton, T.; Chockalingam, A.; Kumar, S.; Angel, M.; Shao, H.; Chen, H.; Li, W.; Perez, D.R. Influenza viruses with rearranged genomes as live-attenuated vaccines. J. Virol. 2013, 87, 5118–5127. [CrossRef] [PubMed]
15. Hall, M.P.; Unch, J.; Binkowski, B.F.; Valley, M.P.; Butler, B.L.; Wood, M.G.; Otto, P.; Zimmerman, K.; Vidugiris, G.; Machleidt, T.; et al. Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate. ACS Chem. Biol. 2012, 7, 1848–1857. [CrossRef] [PubMed]
16. Neumann, G.; Fujii, K.; Kino, Y.; Kawaoka, Y. An improved reverse genetics system for influenza A virus generation and its implications for vaccine production. Proc. Natl. Acad. Sci. USA 2005, 102, 16825–16829. [CrossRef] [PubMed]
17. Mehle, A.; Doudna, J.A. An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase. Cell Host Microbe 2008, 4, 111–122. [CrossRef] [PubMed]
18. Hoffmann, E.; Neumann, G.; Kawaoka, Y.; Hobom, G.; Webster, R.G. A DNA transfection system for generation of influenza A virus from eight plasmids. Proc. Natl. Acad. Sci. USA 2000, 97, 6108–6113. [CrossRef] [PubMed]
19. Chase, G.P.; Rameix-Welti, M.-A.; Zvirbliene, A.; Zvirblis, G.; Götz, V.; Wolff, T.; Naffakh, N.; Schwemmle, M. Influenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting. PLoS Pathog. 2011, 7, e1002187. [CrossRef] [PubMed]
20. Kirui, J.; Bucci, M.D.; Poole, D.S.; Mehle, A. Conserved features of the PB2 627 domain impact influenza virus polymerase function and replication. J. Virol. 2014, 88, 5977–5986. [CrossRef] [PubMed]
21. Baumgarth, N.; Carroll, M.C.; Gonzalez, S. Antibody-mediated immunity. In Textbook of Influenza; John Wiley & Sons, Ltd: Oxford, UK, 2013; pp. 283–297.
22. Hahon, N.; Booth, J.A.; Eckert, H.L. Cell Attachment and Penetration by Influenza Virus. Infect. Immun. 1973, 7, 341–351. [PubMed]
23. Brooke, C.B.; Ince, W.L.; Wrammert, J.; Ahmed, R.; Wilson, P.C.; Bennink, J.R.; Yewdell, J.W. Most influenza a virions fail to express at least one essential viral protein. J. Virol. 2013, 87, 3155–3162. [CrossRef] [PubMed]
24. Barry, R.D. The multiplication of influenza virus. II. Multiplicity reactivation of ultraviolet irradiated virus. Virology 1961, 14, 398–405. [CrossRef]
25. Jonsson, C.B.; Camp, J.V.; Wu, A.; Zheng, H.; Kraenzle, J.L.; Biller, A.E.; Vanover, C.D.; Chu, Y.-K.; Ng, C.K.; Proctor, M.; et al. Molecular Imaging Reveals a Progressive Pulmonary Inflammation in Lower Airways in Ferrets Infected with 2009 H1N1 Pandemic Influenza Virus. PLoS ONE 2012, 7, e40094. [CrossRef] [PubMed]