-
1
-
-
0026503664
-
Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium
-
Chang K, Pastan I, Willingham MC. Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium. Int.J.Cancer. 1992; 50:373-381.
-
(1992)
Int.J.Cancer.
, vol.50
, pp. 373-381
-
-
Chang, K.1
Pastan, I.2
Willingham, M.C.3
-
2
-
-
0034071034
-
Mesothelin is not required for normal mouse development or reproduction
-
Bera TK, Pastan I. Mesothelin is not required for normal mouse development or reproduction. Mol.Cell.Biol. 2000; 20:2902-2906.
-
(2000)
Mol.Cell.Biol.
, vol.20
, pp. 2902-2906
-
-
Bera, T.K.1
Pastan, I.2
-
3
-
-
28444437055
-
Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis
-
Hassan R, Laszik ZG, Lerner M, Raffeld M, Postier R, Brackett D. Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis. Am.J.Clin.Pathol. 2005; 124:838-845.
-
(2005)
Am.J.Clin.Pathol.
, vol.124
, pp. 838-845
-
-
Hassan, R.1
Laszik, Z.G.2
Lerner, M.3
Raffeld, M.4
Postier, R.5
Brackett, D.6
-
4
-
-
3042621639
-
Mesothelin: a new target for immunotherapy
-
Hassan R, Bera T, Pastan I. Mesothelin: a new target for immunotherapy. Clin.Cancer Res. 2004; 10:3937-3942.
-
(2004)
Clin.Cancer Res.
, vol.10
, pp. 3937-3942
-
-
Hassan, R.1
Bera, T.2
Pastan, I.3
-
5
-
-
0038207068
-
Large-scale molecular and tissue microarray analysis of mesothelin expression in common human carcinomas
-
Frierson HF Jr, Moskaluk CA, Powell SM, Zhang H, Cerilli LA, Stoler MH, Cathro H, Hampton GM. Large-scale molecular and tissue microarray analysis of mesothelin expression in common human carcinomas. Hum.Pathol. 2003; 34:605-609.
-
(2003)
Hum.Pathol.
, vol.34
, pp. 605-609
-
-
Frierson, H.F.1
Moskaluk, C.A.2
Powell, S.M.3
Zhang, H.4
Cerilli, L.A.5
Stoler, M.H.6
Cathro, H.7
Hampton, G.M.8
-
6
-
-
84896696863
-
Mesothelin overexpression is a marker of tumor aggressiveness and is associated with reduced recurrence-free and overall survival in early-stage lung adenocarcinoma
-
Kachala SS, Bograd AJ, Villena-Vargas J, Suzuki K, Servais EL, Kadota K, Chou J, Sima CS, Vertes E, Rusch VW, Travis WD, Sadelain M, Adusumilli PS. Mesothelin overexpression is a marker of tumor aggressiveness and is associated with reduced recurrence-free and overall survival in early-stage lung adenocarcinoma. Clin. Cancer Res. 2014; 20:1020-1028.
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 1020-1028
-
-
Kachala, S.S.1
Bograd, A.J.2
Villena-Vargas, J.3
Suzuki, K.4
Servais, E.L.5
Kadota, K.6
Chou, J.7
Sima, C.S.8
Vertes, E.9
Rusch, V.W.10
Travis, W.D.11
Sadelain, M.12
Adusumilli, P.S.13
-
7
-
-
84863727010
-
Mesothelin, a novel immunotherapy target for triple negative breast cancer
-
Tchou J, Wang LC, Selven B, Zhang H, Conejo-Garcia J, Borghaei H, Kalos M, Vondeheide RH, Albelda SM, June CH, Zhang PJ. Mesothelin, a novel immunotherapy target for triple negative breast cancer. Breast Cancer Res.Treat. 2012; 133:799-804.
-
(2012)
Breast Cancer Res.Treat.
, vol.133
, pp. 799-804
-
-
Tchou, J.1
Wang, L.C.2
Selven, B.3
Zhang, H.4
Conejo-Garcia, J.5
Borghaei, H.6
Kalos, M.7
Vondeheide, R.H.8
Albelda, S.M.9
June, C.H.10
Zhang, P.J.11
-
8
-
-
84918568011
-
Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival
-
Tozbikian G, Brogi E, Kadota K, Catalano J, Akram M, Patil S, Ho AY, Reis-Filho JS, Weigelt B, Norton L, Adusumilli PS, Wen HY. Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival. PLoS One. 2014; 9:e114900.
-
(2014)
PLoS One.
, vol.9
-
-
Tozbikian, G.1
Brogi, E.2
Kadota, K.3
Catalano, J.4
Akram, M.5
Patil, S.6
Ho, A.Y.7
Reis-Filho, J.S.8
Weigelt, B.9
Norton, L.10
Adusumilli, P.S.11
Wen, H.Y.12
-
9
-
-
84883821225
-
Antibody therapeutics in cancer
-
Sliwkowski MX, Mellman I. Antibody therapeutics in cancer. Science. 2013; 341:1192-1198.
-
(2013)
Science.
, vol.341
, pp. 1192-1198
-
-
Sliwkowski, M.X.1
Mellman, I.2
-
10
-
-
34247876138
-
Development trends for monoclonal antibody cancer therapeutics
-
Reichert JM, Valge-Archer VE. Development trends for monoclonal antibody cancer therapeutics. Nat.Rev.Drug Discov. 2007; 6:349-356.
-
(2007)
Nat.Rev.Drug Discov.
, vol.6
, pp. 349-356
-
-
Reichert, J.M.1
Valge-Archer, V.E.2
-
11
-
-
80054098573
-
Antibody conjugate therapeutics: challenges and potential
-
Teicher BA, Chari RV. Antibody conjugate therapeutics: challenges and potential. Clin.Cancer Res. 2011; 17:6389-6397.
-
(2011)
Clin.Cancer Res.
, vol.17
, pp. 6389-6397
-
-
Teicher, B.A.1
Chari, R.V.2
-
12
-
-
84925032574
-
Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer antigen 125
-
Hassan R, Sharon E, Thomas A, Zhang J, Ling A, Miettinen M, Kreitman RJ, Steinberg SM, Hollevoet K, Pastan I. Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer antigen 125. Cancer. 2014; 120:3311-3319.
-
(2014)
Cancer.
, vol.120
, pp. 3311-3319
-
-
Hassan, R.1
Sharon, E.2
Thomas, A.3
Zhang, J.4
Ling, A.5
Miettinen, M.6
Kreitman, R.J.7
Steinberg, S.M.8
Hollevoet, K.9
Pastan, I.10
-
13
-
-
84929431322
-
Safety and survival with GVAX pancreas prime and Listeria monocytogenesexpressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer
-
Le DT, Wang-Gillam A, Picozzi V, Greten TF, Crocenzi T, Springett G, Morse M, Zeh H, Cohen D, Fine RL, Onners B, Uram JN, Laheru DA, et al. Safety and survival with GVAX pancreas prime and Listeria monocytogenesexpressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer. J.Clin.Oncol. 2015; 33:1325-1333.
-
(2015)
J.Clin.Oncol.
, vol.33
, pp. 1325-1333
-
-
Le, D.T.1
Wang-Gillam, A.2
Picozzi, V.3
Greten, T.F.4
Crocenzi, T.5
Springett, G.6
Morse, M.7
Zeh, H.8
Cohen, D.9
Fine, R.L.10
Onners, B.11
Uram, J.N.12
Laheru, D.A.13
-
14
-
-
84933526394
-
Chimeric antigen receptor T cells for cancer immunotherapy
-
Curran KJ, Brentjens RJ. Chimeric antigen receptor T cells for cancer immunotherapy. J.Clin.Oncol. 2015; 33:1703-1706.
-
(2015)
J.Clin.Oncol.
, vol.33
, pp. 1703-1706
-
-
Curran, K.J.1
Brentjens, R.J.2
-
15
-
-
84996572349
-
Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies
-
Beatty GL, Haas AR, Maus MV, Torigian DA, Soulen MC, Plesa G, Chew A, Zhao Y, Levine BL, Albelda SM, Kalos M, June CH. Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies. Cancer.Immunol.Res. 2014; 2:112-120.
-
(2014)
Cancer.Immunol.Res.
, vol.2
, pp. 112-120
-
-
Beatty, G.L.1
Haas, A.R.2
Maus, M.V.3
Torigian, D.A.4
Soulen, M.C.5
Plesa, G.6
Chew, A.7
Zhao, Y.8
Levine, B.L.9
Albelda, S.M.10
Kalos, M.11
June, C.H.12
-
16
-
-
84964308876
-
Gene expression analysis identifies global gene dosage sensitivity in cancer
-
Fehrmann RS, Karjalainen JM, Krajewska M, Westra HJ, Maloney D, Simeonov A, Pers TH, Hirschhorn JN, Jansen RC, Schultes EA, van Haagen HH, de Vries EG, te Meerman GJ, et al. Gene expression analysis identifies global gene dosage sensitivity in cancer. Nat.Genet. 2015; 47:115-125.
-
(2015)
Nat.Genet.
, vol.47
, pp. 115-125
-
-
Fehrmann, R.S.1
Karjalainen, J.M.2
Krajewska, M.3
Westra, H.J.4
Maloney, D.5
Simeonov, A.6
Pers, T.H.7
Hirschhorn, J.N.8
Jansen, R.C.9
Schultes, E.A.10
van Haagen, H.H.11
de Vries, E.G.12
te Meerman, G.J.13
-
17
-
-
0035674996
-
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE)
-
Argani P, Iacobuzio-Donahue C, Ryu B, Rosty C, Goggins M, Wilentz RE, Murugesan SR, Leach SD, Jaffee E, Yeo CJ, Cameron JL, Kern SE, Hruban RH. Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin.Cancer Res. 2001; 7:3862-3868.
-
(2001)
Clin.Cancer Res.
, vol.7
, pp. 3862-3868
-
-
Argani, P.1
Iacobuzio-Donahue, C.2
Ryu, B.3
Rosty, C.4
Goggins, M.5
Wilentz, R.E.6
Murugesan, S.R.7
Leach, S.D.8
Jaffee, E.9
Yeo, C.J.10
Cameron, J.L.11
Kern, S.E.12
Hruban, R.H.13
-
18
-
-
0142169984
-
Application of mesothelin immunostaining in tumor diagnosis
-
Ordonez NG. Application of mesothelin immunostaining in tumor diagnosis. Am.J.Surg.Pathol. 2003; 27:1418-1428.
-
(2003)
Am.J.Surg.Pathol.
, vol.27
, pp. 1418-1428
-
-
Ordonez, N.G.1
-
19
-
-
84903179564
-
Diagnostic utility of immunohistochemistry in distinguishing between epithelioid pleural mesotheliomas and breast carcinomas: a comparative study
-
Ordonez NG, Sahin AA. Diagnostic utility of immunohistochemistry in distinguishing between epithelioid pleural mesotheliomas and breast carcinomas: a comparative study. Hum.Pathol. 2014; 45:1529-1540.
-
(2014)
Hum.Pathol.
, vol.45
, pp. 1529-1540
-
-
Ordonez, N.G.1
Sahin, A.A.2
-
20
-
-
84869773333
-
Intracellular localization of mesothelin predicts patient prognosis of extrahepatic bile duct cancer
-
Kawamata F, Kamachi H, Einama T, Homma S, Tahara M, Miyazaki M, Tanaka S, Kamiyama T, Nishihara H, Taketomi A, Todo S. Intracellular localization of mesothelin predicts patient prognosis of extrahepatic bile duct cancer. Int.J.Oncol. 2012; 41:2109-2118.
-
(2012)
Int.J.Oncol.
, vol.41
, pp. 2109-2118
-
-
Kawamata, F.1
Kamachi, H.2
Einama, T.3
Homma, S.4
Tahara, M.5
Miyazaki, M.6
Tanaka, S.7
Kamiyama, T.8
Nishihara, H.9
Taketomi, A.10
Todo, S.11
-
21
-
-
84895076021
-
C-ERC/ mesothelin provokes lymphatic invasion of colorectal adenocarcinoma
-
Kawamata F, Homma S, Kamachi H, Einama T, Kato Y, Tsuda M, Tanaka S, Maeda M, Kajino K, Hino O, Takahashi N, Kamiyama T, Nishihara H, et al. C-ERC/ mesothelin provokes lymphatic invasion of colorectal adenocarcinoma. J.Gastroenterol. 2014; 49:81-92.
-
(2014)
J.Gastroenterol.
, vol.49
, pp. 81-92
-
-
Kawamata, F.1
Homma, S.2
Kamachi, H.3
Einama, T.4
Kato, Y.5
Tsuda, M.6
Tanaka, S.7
Maeda, M.8
Kajino, K.9
Hino, O.10
Takahashi, N.11
Kamiyama, T.12
Nishihara, H.13
-
22
-
-
84859387466
-
Tissue and serum mesothelin are potential markers of neoplastic progression in Barrett's associated esophageal adenocarcinoma
-
Rizk NP, Servais EL, Tang LH, Sima CS, Gerdes H, Fleisher M, Rusch VW, Adusumilli PS. Tissue and serum mesothelin are potential markers of neoplastic progression in Barrett's associated esophageal adenocarcinoma. Cancer Epidemiol.Biomarkers Prev. 2012; 21:482-486.
-
(2012)
Cancer Epidemiol.Biomarkers Prev.
, vol.21
, pp. 482-486
-
-
Rizk, N.P.1
Servais, E.L.2
Tang, L.H.3
Sima, C.S.4
Gerdes, H.5
Fleisher, M.6
Rusch, V.W.7
Adusumilli, P.S.8
-
23
-
-
84891919468
-
ERC/mesothelin is expressed in human gastric cancer tissues and cell lines
-
Ito T, Kajino K, Abe M, Sato K, Maekawa H, Sakurada M, Orita H, Wada R, Kajiyama Y, Hino O. ERC/mesothelin is expressed in human gastric cancer tissues and cell lines. Oncol.Rep. 2014; 31:27-33.
-
(2014)
Oncol.Rep.
, vol.31
, pp. 27-33
-
-
Ito, T.1
Kajino, K.2
Abe, M.3
Sato, K.4
Maekawa, H.5
Sakurada, M.6
Orita, H.7
Wada, R.8
Kajiyama, Y.9
Hino, O.10
-
24
-
-
84863006209
-
Luminal membrane expression of mesothelin is a prominent poor prognostic factor for gastric cancer
-
Einama T, Homma S, Kamachi H, Kawamata F, Takahashi K, Takahashi N, Taniguchi M, Kamiyama T, Furukawa H, Matsuno Y, Tanaka S, Nishihara H, Taketomi A, et al. Luminal membrane expression of mesothelin is a prominent poor prognostic factor for gastric cancer. Br.J.Cancer. 2012; 107:137-142.
-
(2012)
Br.J.Cancer.
, vol.107
, pp. 137-142
-
-
Einama, T.1
Homma, S.2
Kamachi, H.3
Kawamata, F.4
Takahashi, K.5
Takahashi, N.6
Taniguchi, M.7
Kamiyama, T.8
Furukawa, H.9
Matsuno, Y.10
Tanaka, S.11
Nishihara, H.12
Taketomi, A.13
-
25
-
-
34247860743
-
S100A4 protein and mesothelin expression in dysplasia and carcinoma of the extrahepatic bile duct
-
Zhao H, Davydova L, Mandich D, Cartun RW, Ligato S. S100A4 protein and mesothelin expression in dysplasia and carcinoma of the extrahepatic bile duct. Am.J.Clin.Pathol. 2007; 127:374-379.
-
(2007)
Am.J.Clin.Pathol.
, vol.127
, pp. 374-379
-
-
Zhao, H.1
Davydova, L.2
Mandich, D.3
Cartun, R.W.4
Ligato, S.5
-
26
-
-
84874996116
-
Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary
-
Bauerschlag D, Brautigam K, Moll R, Sehouli J, Mustea A, Salehin D, Krajewska M, Reed JC, Maass N, Hampton GM, Meinhold-Heerlein I. Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary. J.Cancer Res.Clin.Oncol. 2013; 139:347-355.
-
(2013)
J.Cancer Res.Clin.Oncol.
, vol.139
, pp. 347-355
-
-
Bauerschlag, D.1
Brautigam, K.2
Moll, R.3
Sehouli, J.4
Mustea, A.5
Salehin, D.6
Krajewska, M.7
Reed, J.C.8
Maass, N.9
Hampton, G.M.10
Meinhold-Heerlein, I.11
-
27
-
-
0035674996
-
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE)
-
Argani P, Iacobuzio-Donahue C, Ryu B, Rosty C, Goggins M, Wilentz RE, Murugesan SR, Leach SD, Jaffee E, Yeo CJ, Cameron JL, Kern SE, Hruban RH. Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin.Cancer Res. 2001; 7:3862-3868.
-
(2001)
Clin.Cancer Res.
, vol.7
, pp. 3862-3868
-
-
Argani, P.1
Iacobuzio-Donahue, C.2
Ryu, B.3
Rosty, C.4
Goggins, M.5
Wilentz, R.E.6
Murugesan, S.R.7
Leach, S.D.8
Jaffee, E.9
Yeo, C.J.10
Cameron, J.L.11
Kern, S.E.12
Hruban, R.H.13
-
28
-
-
84940512059
-
A phase I study of DMOT4039A, an antibody-drug conjugate (ADC) targeting mesothelin (MSLN), in patients (pts) with unresectable pancreatic (PC) or platinum resistant ovarian cancer (OC)
-
suppl
-
Weekes C, Lamberts LE, Borad MJ, Voortman J, McWilliams RR, Robinson Diamond J, de Vries EGE, Verheul HMW, Hanyoung Lieu C, Yue H, Wang Y, Scales S, Samineni D, et al. A phase I study of DMOT4039A, an antibody-drug conjugate (ADC) targeting mesothelin (MSLN), in patients (pts) with unresectable pancreatic (PC) or platinum resistant ovarian cancer (OC). J Clin Oncol. ( suppl; abstr 2529).2014.
-
(2014)
J Clin Oncol
-
-
Weekes, C.1
Lamberts, L.E.2
Borad, M.J.3
Voortman, J.4
McWilliams, R.R.5
Robinson Diamond, J.6
de Vries, E.G.E.7
Verheul, H.M.W.8
Hanyoung Lieu, C.9
Yue, H.10
Wang, Y.11
Scales, S.12
Samineni, D.13
-
29
-
-
84963723793
-
First-in-human phase I dose escalation study of a novel anti-mesothelin antibody drug conjugate (ADC), BAY 94-9343, in patients with advanced solid tumors
-
Bendell J, Blumenschein G, Zinner R, Hong D, Jones S, Infante J, Burris H, Rajagopalan P, Kornacker M, Henderson D, Kelly A, Hassan R. First-in-human phase I dose escalation study of a novel anti-mesothelin antibody drug conjugate (ADC), BAY 94-9343, in patients with advanced solid tumors. Cancer Res AACR abstract # LB-291. 2013.
-
(2013)
Cancer Res AACR abstract # LB-291
-
-
Bendell, J.1
Blumenschein, G.2
Zinner, R.3
Hong, D.4
Jones, S.5
Infante, J.6
Burris, H.7
Rajagopalan, P.8
Kornacker, M.9
Henderson, D.10
Kelly, A.11
Hassan, R.12
-
30
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lonning PE, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc.Natl.Acad.Sci.U.S.A. 2003; 100:8418-8423.
-
(2003)
Proc.Natl.Acad.Sci.U.S.A.
, vol.100
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
Hastie, T.4
Marron, J.S.5
Nobel, A.6
Deng, S.7
Johnsen, H.8
Pesich, R.9
Geisler, S.10
Demeter, J.11
Perou, C.M.12
Lonning, P.E.13
-
31
-
-
62449131093
-
Supervised risk predictor of breast cancer based on intrinsic subtypes
-
Parker JS, Mullins M, Cheang MC, Leung S, Voduc D, Vickery T, Davies S, Fauron C, He X, Hu Z, Quackenbush JF, Stijleman IJ, Palazzo J, et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J.Clin.Oncol. 2009; 27:1160-1167.
-
(2009)
J.Clin.Oncol.
, vol.27
, pp. 1160-1167
-
-
Parker, J.S.1
Mullins, M.2
Cheang, M.C.3
Leung, S.4
Voduc, D.5
Vickery, T.6
Davies, S.7
Fauron, C.8
He, X.9
Hu, Z.10
Quackenbush, J.F.11
Stijleman, I.J.12
Palazzo, J.13
-
32
-
-
33646874546
-
The molecular portraits of breast tumors are conserved across microarray platforms
-
Hu Z, Fan C, Oh DS, Marron JS, He X, Qaqish BF, Livasy C, Carey LA, Reynolds E, Dressler L, Nobel A, Parker J, Ewend MG, et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics. 2006; 7:96.
-
(2006)
BMC Genomics.
, vol.7
, pp. 96
-
-
Hu, Z.1
Fan, C.2
Oh, D.S.3
Marron, J.S.4
He, X.5
Qaqish, B.F.6
Livasy, C.7
Carey, L.A.8
Reynolds, E.9
Dressler, L.10
Nobel, A.11
Parker, J.12
Ewend, M.G.13
-
33
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, Pietenpol JA. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J.Clin.Invest. 2011; 121:2750-2767.
-
(2011)
J.Clin.Invest.
, vol.121
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
Sanders, M.E.4
Chakravarthy, A.B.5
Shyr, Y.6
Pietenpol, J.A.7
|