Iatrogenic hypomagnesemia: An underestimated clinical problem

Italian Journal of Medicine

Volumn 9, Issue 3, 2015, Pages 287-289

  Villa, Antonio ^a   Zanada, Paolo ^a   Pellegrino, Adriana ^a   Nucera, Gabriella ^a   Martinoli, Elena ^a   Boschiero, Annamaria ^a   Campanini, Francesca ^a  

^a FATEBENEFRATELLI HOSPITAL   (Italy)

Author keywords

Diuretics; Hypomagnesemia; Metformin; Proton pump inhibitors

Indexed keywords

DIURETIC AGENT; MAGNESIUM; METFORMIN; PROTON PUMP INHIBITOR;

ALCOHOLISM; ARTICLE; CHRONIC DIARRHEA; CROHN DISEASE; DIABETES MELLITUS; ELECTROCARDIOGRAM; GASTROINTESTINAL DISEASE; HUMAN; HYPOMAGNESEMIA; IATROGENIC DISEASE; IATROGENIC HYPOMAGNESEMIA; KIDNEY DISEASE; LIVER CIRRHOSIS; LONG TERM CARE; MAGNESIUM BLOOD LEVEL; MAGNESIUM METABOLISM; MAJOR CLINICAL STUDY; RETROSPECTIVE STUDY; SEIZURE; VOMITING;

EID: 84944387907     PISSN: 18779344     EISSN: 18779352     Source Type: Journal    
DOI: 10.4081/itjm.2015.521     Document Type: Article

References (20)

1. Wong ET, Rude RK, Singer FR, Shaw ST Jr. A high prevalence of hypomagnesemia and hypermagnesemia in hospitalized patients. Am J Clin Pathol 1983;79: 348-52.
2. Florentin M, Elisaf MS. Proton pump inhibitor-induced hypomagnesemia: a new challenge. WJN 2012;1:151-4.
3. Walti MK, Zimmermann MB, Spinas GA, Hurrel RF. Low plasma magnesium in type 2 diabetes. Swiss Med Wkly 2003;133:289-92.
4. Epstein M, McGrath S, Law F. Proton-pump inhibitors and hypomagnesemic hypo-parathyroidism. N Engl J Med 2006;355;1834-6.
5. Cundy T, Mackay J. Proton pump inhibitors and severe hypomagnesemia. Curr Opin Gastroenterol 2011;27:180-5.
6. Kuipers MT, Thang HD, Arntzenius AB. Hypomagnesemia due to use of proton pump inhibitors - a review. Neth J Med 2009;67:169-72.
7. Mackay JD, Bladon PT. Hypomagnesemia due to proton-pump inhibitor therapy: a clical case series. QJM 2010;103:387-95.
8. Hoorn EJ, van der Hock J, de Man RA, et al. A case series of proton pump inhibitor-induced hypomagnesemia. Am J Kidney Dis 2010;56:112-6.
9. Cundy T, Dissanayake A. Severe hypomagnesemia in long-term users of proton-pump inhibitors. Clin Endocrinol 2008;69:338-41.
10. Lameris AL, Monnens LA, Bindels RJ, Hoenderop JGJ. Drug-induced alterations in Mg2+ homeostasis. Clin Sci 2012;123:1-14.
11. Pham PC, Pham PA, Pham SV, et al. Hypomagnesemia: a clinical perspective. Int J Nephrol Renovasc Dis 2014; 7:219-30.
12. Regolisti G, Cabassi A, Parenti E, et al. Severe hypomagnesemia during long-term treatment with a proton pump inhibitors. Am J Kidney Dis 2010;56:168-74.
13. El-Charabaty E, Saifan C, Abdallah M, et al. Effects of proton pump inhibitors and eletrolyte disturbances on arrhythmias. Int J Gen Med 2013;6:515-8.
14. Pham PC, Pham PM, Pham SV, et al. Hypomagnesemia in patients with type 2 diabetes. Cli J Am Soc Nephrol 2007;2:366-73.
15. Chaudhary DP, Sharma R, Bansal DD. Implications of magnesium deficiency in type 2 diabetes: a review. Biol Trace Elem Res 2010;134:119-29.
16. Ma J, Folsom AR, Melnick SL, et al. Associations of serum and dietary magnesium with cardiovascular disease, hypertension, diabetes, insulin and carotid arterial wall thickness: the RIC study. Atherosclerosis Risk in Communities Study. J Clin Epidemiol 1995;48:927-40.
17. Dosa MD, Hangan LT, Crauciuc E, et al. Influence of therapy with metformin on the concentration of certain divalent actions in patients with non-insulin-dipendent diabetes mellitus. Biol Trace Elem Res 2011;142:36-46.
18. Gorelik O, Efrati S, Berman S, et al. Effect of various clinical variables on total intracellular magnesium in hospitalized normomagnesemic diabetic patients before discharge. Biol Trace Elem Res 2007;120:102-9.
19. Furlanetto TW, Faulhaber GA. Hypomagnesemia and proton pump inhibitors: below the tip of the iceberg. Arch Intern Med 2011;171:1391-2.
20. Famularo G, Gasbarrone L, Minisola G. Hypomagnesemia and proton-pump inhibitors. Expert Opin Drug Saf 2013;12:709-16.