High expression of WISP-1 correlates with poor prognosis in pancreatic ductal adenocarcinoma

American Journal of Translational Research

Volumn 7, Issue 9, 2015, Pages 1621-1628

  Yang, Jian Yu ^a   Yang, Min Wei ^a   Huo, Yan Miao ^a   Liu, Wei ^a   Liu, De Jun ^a   Li, Jiao ^a   Zhang, Jun Feng ^a   Hua, Rong ^a   Sun, Yong Wei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Pancreatic ductal adenocarcinoma; Prognosis; WISP 1

Indexed keywords

MESSENGER RNA; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; WNT1 INDUCIBLE SIGNALING PATHWAY PROTEIN 1;

ADULT; AGED; ARTICLE; BIOPSY; CANCER PROGNOSIS; CANCER STAGING; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDY; RNA EXTRACTION; SURVIVAL TIME; TISSUE MICROARRAY; UPREGULATION; WESTERN BLOTTING;

EID: 84944328573     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Siegel RL, Miller KD and Jemal A. Cancer statistics, 2015. CA Cancer J Clin 2015; 65: 5-29
2. Pennica D, Swanson TA, Welsh JW, Roy MA, Lawrence DA, Lee J, Brush J, Taneyhill LA, Deuel B, Lew M, Watanabe C, Cohen RL, Melhem MF, Finley GG, Quirke P, Goddard AD, Hillan KJ, Gurney AL, Botstein D, Levine AJ. WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proc Natl Acad Sci U S A 1998; 95: 14717-14722
3. Xu L, Corcoran RB, Welsh JW, Pennica D and Levine AJ. WISP-1 is a Wnt-1and beta-cateninresponsive oncogene. Genes Dev 2000; 14: 585-595
4. Brigstock DR. The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family. Endocr Rev 1999; 20: 189-206
5. Lau LF and Lam SC. The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res 1999; 248: 44-57
6. Perbal B. The CCN family of genes: a brief history. Mol Pathol 2001; 54: 103-104
7. Perbal B, Brigstock D and Lau L. Report on the second international workshop on the CCN family of genes. Molecular Pathology 2003; 56: 80
8. Stephens S, Palmer J, Konstantinova I, Pearce A, Jarai G and Day E. A functional analysis of Wnt inducible signalling pathway protein-1 (WISP-1/CCN4). J Cell Commun Signal 2015; 63-72
9. Gurbuz I and Chiquet-Ehrismann R. CCN4/ WISP1 (WNT1 inducible signaling pathway protein 1): A focus on its role in cancer. The international journal of biochemistry & cell biology 2015; 62: 142-146
10. Nagai Y, Watanabe M, Ishikawa S, Karashima R, Kurashige J, Iwagami S, Iwatsuki M, Baba Y, Imamura Y and Hayashi N. Clinical significance of Wnt-induced secreted protein-1 (WISP-1/ CCN4) in esophageal squamous cell carcinoma. Anticancer Res 2011; 31: 991-997
11. Li J, Yang XM, Wang YH, Feng MX, Liu XJ, Zhang YL, Huang S, Wu Z, Xue F, Qin WX, Gu JR, Xia Q and Zhang ZG. Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling. J Hepatol 2014; 60: 1225-1234
12. Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, Walter K, Nikolskaya T, Nikolsky Y, Hartigan J, Smith DR, Hidalgo M, Leach SD, Klein AP, Jaffee EM, Goggins M, Maitra A, Iacobuzio-Donahue C, Eshleman JR, Kern SE, Hruban RH, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE and Kinzler KW. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008; 321: 1801-1806
13. Heiser PW, Cano DA, Landsman L, Kim GE, Kench JG, Klimstra DS, Taketo MM, Biankin AV and Hebrok M. Stabilization of beta-catenin induces pancreas tumor formation. Gastroenterology 2008; 135: 1288-1300
14. Zhang H, Luo H, Hu Z, Peng J, Jiang Z, Song T, Wu B, Yue J, Zhou R, Xie R, Chen T and Wu S. Targeting WISP1 to sensitize esophageal squamous cell carcinoma to irradiation. Oncotarget 2015; 6: 6218-6234
15. Xie D, Nakachi K, Wang H, Elashoff R and Koeffler HP. Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features. Cancer Res 2001; 61: 8917-8923
16. Davies SR, Davies ML, Sanders A, Parr C, Torkington J and Jiang WG. Differential expression of the CCN family member WISP-1, WISP-2 and WISP-3 in human colorectal cancer and the prognostic implications. Int J Oncol 2010; 36: 1129-1136
17. Chen PP, Li WJ, Wang Y, Zhao S, Li DY, Feng LY, Shi XL, Koeffler HP, Tong XJ and Xie D. Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer. PLoS One 2007; 2: e534
18. Nagai Y, Watanabe M, Ishikawa S, Karashima R, Kurashige J, Iwagami S, Iwatsuki M, Baba Y, Imamura Y, Hayashi N and Baba H. Clinical significance of Wnt-induced secreted protein-1 (WISP-1/CCN4) in esophageal squamous cell carcinoma. Anticancer Res 2011; 31: 991-997
19. Tanaka S, Sugimachi K, Kameyama T, Maehara S, Shirabe K, Shimada M, Wands JR and Maehara Y. Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma. Hepatology 2003; 37: 1122-1129
20. Su F, Overholtzer M, Besser D and Levine AJ. WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. Genes Dev 2002; 16: 46-57
21. Soon LL, Yie TA, Shvarts A, Levine AJ, Su F and Tchou-Wong KM. Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation. J Biol Chem 2003; 278: 11465-11470