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Volumn 15, Issue 12, 2015, Pages

Hypoglycemia and Cardiovascular Disease: Lessons from Outcome Studies

Author keywords

Cardiovascular risk; Diabetes; Hypoglycemia; Outcome trials

Indexed keywords

ADULT; AGED; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIABETES CONTROL; DISEASE SEVERITY; HAZARD RATIO; HEART ARRHYTHMIA; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; INCIDENCE; LIFE EXPECTANCY; MIDDLE AGED; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; PROSPECTIVE STUDY; REVIEW; RISK FACTOR; SUDDEN DEATH; CARDIOVASCULAR DISEASES; CLINICAL TRIAL (TOPIC); COMPLICATION; OUTCOME ASSESSMENT;

EID: 84944314305     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-015-0678-2     Document Type: Review
Times cited : (9)

References (47)
  • 1
    • 74949117631 scopus 로고    scopus 로고
    • The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study
    • PID: 20061358
    • Bonds DE, Miller ME, Bergenstal RM, Buse JB, Byington RP, Cutler JA, et al. The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study. BMJ. 2010;340:b4909.
    • (2010) BMJ , vol.340 , pp. 4909
    • Bonds, D.E.1    Miller, M.E.2    Bergenstal, R.M.3    Buse, J.B.4    Byington, R.P.5    Cutler, J.A.6
  • 3
    • 84890034047 scopus 로고    scopus 로고
    • Does hypoglycaemia increase the risk of cardiovascular events? A report from the ORIGIN trial
    • COI: 1:CAS:528:DC%2BC3sXhs1OltrnL, PID: 23999452, An excellent analysis of CV events, treatments, and CV risk factors of patients from the ORIGIN trial with vs without hypoglycemia
    • Mellbin LG, Ryden L, Riddle MC, Probstfield J, Rosenstock J, Diaz R, et al. Does hypoglycaemia increase the risk of cardiovascular events? A report from the ORIGIN trial. Eur Heart J. 2013;34:3137–44. An excellent analysis of CV events, treatments, and CV risk factors of patients from the ORIGIN trial with vs without hypoglycemia.
    • (2013) Eur Heart J , vol.34 , pp. 3137-3144
    • Mellbin, L.G.1    Ryden, L.2    Riddle, M.C.3    Probstfield, J.4    Rosenstock, J.5    Diaz, R.6
  • 4
    • 79251567403 scopus 로고    scopus 로고
    • Serious cardiovascular outcomes in diabetes: the role of hypoglycemia
    • PID: 21263007
    • Yakubovich N, Gerstein HC. Serious cardiovascular outcomes in diabetes: the role of hypoglycemia. Circulation. 2011;123:342–8.
    • (2011) Circulation , vol.123 , pp. 342-348
    • Yakubovich, N.1    Gerstein, H.C.2
  • 5
    • 77957742069 scopus 로고    scopus 로고
    • Severe hypoglycemia and risks of vascular events and death
    • COI: 1:CAS:528:DC%2BC3cXhtlGks7fI, PID: 20925543
    • Zoungas S, Patel A, Chalmers J, de Galan BE, Li Q, Billot L, et al. Severe hypoglycemia and risks of vascular events and death. N Engl J Med. 2010;363:1410–8.
    • (2010) N Engl J Med , vol.363 , pp. 1410-1418
    • Zoungas, S.1    Patel, A.2    Chalmers, J.3    de Galan, B.E.4    Li, Q.5    Billot, L.6
  • 6
    • 58149389215 scopus 로고    scopus 로고
    • Glucose control and vascular complications in veterans with type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1MXnsFWkug%3D%3D, PID: 19092145
    • Duckworth W, Abraira C, Moritz T, Reda D, Emanuele N, Reaven PD, et al. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med. 2009;360:129–39.
    • (2009) N Engl J Med , vol.360 , pp. 129-139
    • Duckworth, W.1    Abraira, C.2    Moritz, T.3    Reda, D.4    Emanuele, N.5    Reaven, P.D.6
  • 7
    • 84881416448 scopus 로고    scopus 로고
    • Severe hypoglycaemia and cardiovascular disease: systematic review and meta-analysis with bias analysis
    • PID: 23900314
    • Goto A, Arah OA, Goto M, Terauchi Y, Noda M. Severe hypoglycaemia and cardiovascular disease: systematic review and meta-analysis with bias analysis. BMJ. 2013;347:f4533.
    • (2013) BMJ , vol.347 , pp. 4533
    • Goto, A.1    Arah, O.A.2    Goto, M.3    Terauchi, Y.4    Noda, M.5
  • 8
    • 84862906076 scopus 로고    scopus 로고
    • Severe hypoglycemia and cardiovascular disease incidence in type 1 diabetes: the EURODIAB Prospective Complications Study
    • COI: 1:CAS:528:DC%2BC38Xht1Sht7jI, PID: 22584135
    • Gruden G, Barutta F, Chaturvedi N, Schalkwijk C, Stehouwer CD, Witte DR, et al. Severe hypoglycemia and cardiovascular disease incidence in type 1 diabetes: the EURODIAB Prospective Complications Study. Diabetes Care. 2012;35:1598–604.
    • (2012) Diabetes Care , vol.35 , pp. 1598-1604
    • Gruden, G.1    Barutta, F.2    Chaturvedi, N.3    Schalkwijk, C.4    Stehouwer, C.D.5    Witte, D.R.6
  • 9
    • 84920538565 scopus 로고    scopus 로고
    • Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality
    • Orchard TJ, Nathan DM, Zinman B, Cleary P, Brillon D, Backlund JY, et al. Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality. JAMA. 2015.
    • (2015) JAMA
    • Orchard, T.J.1    Nathan, D.M.2    Zinman, B.3    Cleary, P.4    Brillon, D.5    Backlund, J.Y.6
  • 10
    • 84921931382 scopus 로고    scopus 로고
    • Hypoglycemia and risk of cardiovascular disease and all-cause mortality in insulin-treated people with type 1 and type 2 diabetes: a cohort study
    • PID: 25492401
    • Khunti K, Davies M, Majeed A, Thorsted BL, Wolden ML, Paul SK. Hypoglycemia and risk of cardiovascular disease and all-cause mortality in insulin-treated people with type 1 and type 2 diabetes: a cohort study. Diabetes Care. 2015;38:316–22.
    • (2015) Diabetes Care , vol.38 , pp. 316-322
    • Khunti, K.1    Davies, M.2    Majeed, A.3    Thorsted, B.L.4    Wolden, M.L.5    Paul, S.K.6
  • 11
    • 79952273819 scopus 로고    scopus 로고
    • Long-term effects of intensive glucose lowering on cardiovascular outcomes
    • COI: 1:CAS:528:DC%2BC3MXivV2qurw%3D, PID: 21366473
    • Gerstein HC, Miller ME, Genuth S, Ismail-Beigi F, Buse JB, Goff Jr DC, et al. Long-term effects of intensive glucose lowering on cardiovascular outcomes. N Engl J Med. 2011;364:818–28.
    • (2011) N Engl J Med , vol.364 , pp. 818-828
    • Gerstein, H.C.1    Miller, M.E.2    Genuth, S.3    Ismail-Beigi, F.4    Buse, J.B.5    Goff, D.C.6
  • 12
    • 53749096863 scopus 로고    scopus 로고
    • 10-year follow-up of intensive glucose control in type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1cXht1Wgt7nK, PID: 18784090
    • Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HA. 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med. 2008;359:1577–89.
    • (2008) N Engl J Med , vol.359 , pp. 1577-1589
    • Holman, R.R.1    Paul, S.K.2    Bethel, M.A.3    Matthews, D.R.4    Neil, H.A.5
  • 13
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1cXnt1yht7s%3D, PID: 18539916
    • Patel A, MacMahon S, Chalmers J, Neal B, Billot L, Woodward M, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008;358:2560–72.
    • (2008) N Engl J Med , vol.358 , pp. 2560-2572
    • Patel, A.1    MacMahon, S.2    Chalmers, J.3    Neal, B.4    Billot, L.5    Woodward, M.6
  • 14
    • 0031006603 scopus 로고    scopus 로고
    • Hypoglycemia in the Diabetes Control and Complications Trial
    • The Diabetes Control and Complications Trial Research Group. Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes. 1997;46:271–86.
    • (1997) Diabetes , vol.46 , pp. 271-286
  • 15
    • 84901768284 scopus 로고    scopus 로고
    • Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes
    • COI: 1:CAS:528:DC%2BC2cXpslCrsb8%3D, PID: 24910232, Interesting review which address the problems and limitations of recent outcome trials
    • Holman RR, Sourij H, Califf RM. Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes. Lancet. 2014;383:2008–17. Interesting review which address the problems and limitations of recent outcome trials.
    • (2014) Lancet , vol.383 , pp. 2008-2017
    • Holman, R.R.1    Sourij, H.2    Califf, R.M.3
  • 16
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993;329:977–86.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 17
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837–53.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 19
    • 74949138626 scopus 로고    scopus 로고
    • The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: post hoc epidemiological analysis of the ACCORD study
    • PID: 20061360
    • Miller ME, Bonds DE, Gerstein HC, Seaquist ER, Bergenstal RM, Calles-Escandon J, et al. The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: post hoc epidemiological analysis of the ACCORD study. BMJ. 2010;340:b5444.
    • (2010) BMJ , vol.340 , pp. 5444
    • Miller, M.E.1    Bonds, D.E.2    Gerstein, H.C.3    Seaquist, E.R.4    Bergenstal, R.M.5    Calles-Escandon, J.6
  • 20
    • 84920023912 scopus 로고    scopus 로고
    • Predictors of nonsevere and severe hypoglycemia during glucose-lowering treatment with insulin glargine or standard drugs in the ORIGIN trial
    • Origin Trial Investigators. Predictors of nonsevere and severe hypoglycemia during glucose-lowering treatment with insulin glargine or standard drugs in the ORIGIN trial. Diabetes Care. 2015;38:22–8.
    • (2015) Diabetes Care , vol.38 , pp. 22-28
  • 21
    • 33751003491 scopus 로고    scopus 로고
    • Hypoglycemia in Type 2 diabetic patients randomized to and maintained on monotherapy with diet, sulfonylurea, metformin, or insulin for 6 years from diagnosis: UKPDS73
    • PID: 17070446
    • Wright AD, Cull CA, Macleod KM, Holman RR. Hypoglycemia in Type 2 diabetic patients randomized to and maintained on monotherapy with diet, sulfonylurea, metformin, or insulin for 6 years from diagnosis: UKPDS73. J Diabetes Complicat. 2006;20:395–401.
    • (2006) J Diabetes Complicat , vol.20 , pp. 395-401
    • Wright, A.D.1    Cull, C.A.2    Macleod, K.M.3    Holman, R.R.4
  • 22
    • 84941934888 scopus 로고    scopus 로고
    • Risk of and risk factors for hypoglycemia and associated arrhythmias in patients with type 2 diabetes and cardiovascular disease: a cohort study under real-world conditions
    • Pistrosch F, Ganz X, Bornstein SR, Birkenfeld AL, Henkel E, Hanefeld M. Risk of and risk factors for hypoglycemia and associated arrhythmias in patients with type 2 diabetes and cardiovascular disease: a cohort study under real-world conditions. Acta Diabetol. 2015.
    • (2015) Acta Diabetol
    • Pistrosch, F.1    Ganz, X.2    Bornstein, S.R.3    Birkenfeld, A.L.4    Henkel, E.5    Hanefeld, M.6
  • 23
    • 0025284556 scopus 로고
    • Cardiac responses to acute insulin-induced hypoglycemia in humans
    • COI: 1:CAS:528:DyaK3cXkslWktr4%3D, PID: 1972868
    • Fisher BM, Gillen G, Hepburn DA, Dargie HJ, Frier BM. Cardiac responses to acute insulin-induced hypoglycemia in humans. Am J Physiol. 1990;258:H1775–9.
    • (1990) Am J Physiol , vol.258 , pp. 1775-1779
    • Fisher, B.M.1    Gillen, G.2    Hepburn, D.A.3    Dargie, H.J.4    Frier, B.M.5
  • 25
    • 36148945222 scopus 로고    scopus 로고
    • Vessel wall stiffness in type 1 diabetes and the central hemodynamic effects of acute hypoglycemia
    • COI: 1:CAS:528:DC%2BD2sXhtlenurrO, PID: 17726149
    • Sommerfield AJ, Wilkinson IB, Webb DJ, Frier BM. Vessel wall stiffness in type 1 diabetes and the central hemodynamic effects of acute hypoglycemia. Am J Physiol Endocrinol Metab. 2007;293:E1274–9.
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. 1274-1279
    • Sommerfield, A.J.1    Wilkinson, I.B.2    Webb, D.J.3    Frier, B.M.4
  • 26
    • 84884307733 scopus 로고    scopus 로고
    • Cardiac implications of hypoglycaemia in patients with diabetes— a systematic review
    • PID: 24053606
    • Hanefeld M, Duetting E, Bramlage P. Cardiac implications of hypoglycaemia in patients with diabetes— a systematic review. Cardiovasc Diabetol. 2013;12:135.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 135
    • Hanefeld, M.1    Duetting, E.2    Bramlage, P.3
  • 27
    • 49449109529 scopus 로고    scopus 로고
    • Vascular disease and diabetes: is hypoglycaemia an aggravating factor?
    • COI: 1:CAS:528:DC%2BD1cXhtVKnsr%2FI, PID: 18461635
    • Wright RJ, Frier BM. Vascular disease and diabetes: is hypoglycaemia an aggravating factor? Diabetes Metab Res Rev. 2008;24:353–63.
    • (2008) Diabetes Metab Res Rev , vol.24 , pp. 353-363
    • Wright, R.J.1    Frier, B.M.2
  • 28
    • 84892397775 scopus 로고    scopus 로고
    • Vital signs, QT prolongation, and newly diagnosed cardiovascular disease during severe hypoglycemia in type 1 and type 2 diabetic patients
    • COI: 1:CAS:528:DC%2BC2cXjt1yru7w%3D, PID: 23939540
    • Tsujimoto T, Yamamoto-Honda R, Kajio H, Kishimoto M, Noto H, Hachiya R, et al. Vital signs, QT prolongation, and newly diagnosed cardiovascular disease during severe hypoglycemia in type 1 and type 2 diabetic patients. Diabetes Care. 2014;37:217–25.
    • (2014) Diabetes Care , vol.37 , pp. 217-225
    • Tsujimoto, T.1    Yamamoto-Honda, R.2    Kajio, H.3    Kishimoto, M.4    Noto, H.5    Hachiya, R.6
  • 29
    • 77049199340 scopus 로고
    • Sudden death in insulin coma treatment for schizophrenia
    • COI: 1:STN:280:DyaG2M%2FotlKktg%3D%3D, PID: 14381914
    • Leitch A. Sudden death in insulin coma treatment for schizophrenia. J Nerv Ment Dis. 1955;121:267–9.
    • (1955) J Nerv Ment Dis , vol.121 , pp. 267-269
    • Leitch, A.1
  • 30
    • 77953946695 scopus 로고    scopus 로고
    • Confirmation of hypoglycemia in the "dead-in-bed" syndrome, as captured by a retrospective continuous glucose monitoring system
    • PID: 19833577
    • Tanenberg RJ, Newton CA, Drake AJ. Confirmation of hypoglycemia in the "dead-in-bed" syndrome, as captured by a retrospective continuous glucose monitoring system. Endocr Pract. 2010;16:244–8.
    • (2010) Endocr Pract , vol.16 , pp. 244-248
    • Tanenberg, R.J.1    Newton, C.A.2    Drake, A.J.3
  • 31
    • 0026099752 scopus 로고
    • Unexplained deaths of type 1 diabetic patients
    • COI: 1:STN:280:DyaK3M7otlyhuw%3D%3D, PID: 1826245
    • Tattersall RB, Gill GV. Unexplained deaths of type 1 diabetic patients. Diabet Med. 1991;8:49–58.
    • (1991) Diabet Med , vol.8 , pp. 49-58
    • Tattersall, R.B.1    Gill, G.V.2
  • 32
    • 57249094211 scopus 로고    scopus 로고
    • Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes—the 'dead in bed' syndrome revisited
    • COI: 1:STN:280:DC%2BD1cjotVKnsg%3D%3D, PID: 18972096
    • Gill GV, Woodward A, Casson IF, Weston PJ. Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes—the 'dead in bed' syndrome revisited. Diabetologia. 2009;52:42–5.
    • (2009) Diabetologia , vol.52 , pp. 42-45
    • Gill, G.V.1    Woodward, A.2    Casson, I.F.3    Weston, P.J.4
  • 33
    • 0032875210 scopus 로고    scopus 로고
    • Increased QT dispersion during hypoglycaemia in patients with type 2 diabetes mellitus
    • COI: 1:STN:280:DyaK1Mvgs1Oltg%3D%3D, PID: 10475998
    • Landstedt-Hallin L, Englund A, Adamson U, Lins PE. Increased QT dispersion during hypoglycaemia in patients with type 2 diabetes mellitus. J Intern Med. 1999;246:299–307.
    • (1999) J Intern Med , vol.246 , pp. 299-307
    • Landstedt-Hallin, L.1    Englund, A.2    Adamson, U.3    Lins, P.E.4
  • 34
    • 0030874319 scopus 로고    scopus 로고
    • Altered ventricular repolarization during hypoglycaemia in patients with diabetes
    • COI: 1:STN:280:DyaK2svhslaitQ%3D%3D, PID: 9272590
    • Marques JL, George E, Peacey SR, Harris ND, Macdonald IA, Cochrane T, et al. Altered ventricular repolarization during hypoglycaemia in patients with diabetes. Diabet Med. 1997;14:648–54.
    • (1997) Diabet Med , vol.14 , pp. 648-654
    • Marques, J.L.1    George, E.2    Peacey, S.R.3    Harris, N.D.4    Macdonald, I.A.5    Cochrane, T.6
  • 35
    • 0242494266 scopus 로고    scopus 로고
    • What clinicians should know about the QT interval
    • PID: 12709470
    • Al Khatib SM, LaPointe NM, Kramer JM, Califf RM. What clinicians should know about the QT interval. JAMA. 2003;289:2120–7.
    • (2003) JAMA , vol.289 , pp. 2120-2127
    • Al Khatib, S.M.1    LaPointe, N.M.2    Kramer, J.M.3    Califf, R.M.4
  • 36
    • 84899103023 scopus 로고    scopus 로고
    • Risk of cardiac arrhythmias during hypoglycemia in patients with type 2 diabetes and cardiovascular risk
    • COI: 1:CAS:528:DC%2BC2cXnt1KhtLY%3D, PID: 24757202
    • Chow E, Bernjak A, Williams S, Fawdry RA, Hibbert S, Freeman J, et al. Risk of cardiac arrhythmias during hypoglycemia in patients with type 2 diabetes and cardiovascular risk. Diabetes. 2014;63:1738–47.
    • (2014) Diabetes , vol.63 , pp. 1738-1747
    • Chow, E.1    Bernjak, A.2    Williams, S.3    Fawdry, R.A.4    Hibbert, S.5    Freeman, J.6
  • 37
    • 84893115459 scopus 로고    scopus 로고
    • Relationship between hypoglycemic episodes and ventricular arrhythmias in patients with type 2 diabetes and cardiovascular diseases. silent hypoglycemias and silent arrhythmias
    • COI: 1:CAS:528:DC%2BC2cXks1CqurY%3D, PID: 24041680
    • Stahn A, Pistrosch F, Ganz X, Teige M, Koehler C, Bornstein S, et al. Relationship between hypoglycemic episodes and ventricular arrhythmias in patients with type 2 diabetes and cardiovascular diseases. silent hypoglycemias and silent arrhythmias. Diabetes Care. 2014;37:516–20.
    • (2014) Diabetes Care , vol.37 , pp. 516-520
    • Stahn, A.1    Pistrosch, F.2    Ganz, X.3    Teige, M.4    Koehler, C.5    Bornstein, S.6
  • 38
    • 84927178554 scopus 로고    scopus 로고
    • Hypoglycaemia in diabetes mellitus: epidemiology and clinical implications
    • COI: 1:CAS:528:DC%2BC2cXhslemu7%2FM, PID: 25287289, Comprehensive review of the topic
    • Frier BM. Hypoglycaemia in diabetes mellitus: epidemiology and clinical implications. Nat Rev Endocrinol. 2014;10:711–22. Comprehensive review of the topic.
    • (2014) Nat Rev Endocrinol , vol.10 , pp. 711-722
    • Frier, B.M.1
  • 39
    • 0018777379 scopus 로고
    • Platelet aggregation studies during transient hypoglycaemia: a potential method for evaluating platelet function
    • COI: 1:STN:280:DyaE1M3jvFOntg%3D%3D, PID: 469000
    • Hutton RA, Mikhailidis D, Dormandy KM, Ginsburg J. Platelet aggregation studies during transient hypoglycaemia: a potential method for evaluating platelet function. J Clin Pathol. 1979;32:434–8.
    • (1979) J Clin Pathol , vol.32 , pp. 434-438
    • Hutton, R.A.1    Mikhailidis, D.2    Dormandy, K.M.3    Ginsburg, J.4
  • 40
    • 77957933451 scopus 로고    scopus 로고
    • Effects of acute insulin-induced hypoglycemia on indices of inflammation: putative mechanism for aggravating vascular disease in diabetes
    • COI: 1:CAS:528:DC%2BC3cXpslKgsrs%3D, PID: 20587725
    • Wright RJ, Newby DE, Stirling D, Ludlam CA, Macdonald IA, Frier BM. Effects of acute insulin-induced hypoglycemia on indices of inflammation: putative mechanism for aggravating vascular disease in diabetes. Diabetes Care. 2010;33:1591–7.
    • (2010) Diabetes Care , vol.33 , pp. 1591-1597
    • Wright, R.J.1    Newby, D.E.2    Stirling, D.3    Ludlam, C.A.4    Macdonald, I.A.5    Frier, B.M.6
  • 41
    • 0019970906 scopus 로고
    • Changes in platelet function, blood coagulation and fibrinolysis during insulin-induced hypoglycaemia in juvenile diabetics and normal subjects
    • COI: 1:STN:280:DyaL383nvVSjuw%3D%3D, PID: 7051410
    • Dalsgaard-Nielsen J, Madsbad S, Hilsted J. Changes in platelet function, blood coagulation and fibrinolysis during insulin-induced hypoglycaemia in juvenile diabetics and normal subjects. Thromb Haemost. 1982;47:254–8.
    • (1982) Thromb Haemost , vol.47 , pp. 254-258
    • Dalsgaard-Nielsen, J.1    Madsbad, S.2    Hilsted, J.3
  • 42
    • 77958182585 scopus 로고    scopus 로고
    • Proinflammatory and prothrombotic effects of hypoglycemia
    • PID: 20587729
    • Dandona P, Chaudhuri A, Dhindsa S. Proinflammatory and prothrombotic effects of hypoglycemia. Diabetes Care. 2010;33:1686–7.
    • (2010) Diabetes Care , vol.33 , pp. 1686-1687
    • Dandona, P.1    Chaudhuri, A.2    Dhindsa, S.3
  • 43
    • 77958192003 scopus 로고    scopus 로고
    • Effects of acute hypoglycemia on inflammatory and pro-atherothrombotic biomarkers in individuals with type 1 diabetes and healthy individuals
    • Gogitidze JN, Hedrington MS, Briscoe VJ, Tate DB, Ertl AC, Davis SN. Effects of acute hypoglycemia on inflammatory and pro-atherothrombotic biomarkers in individuals with type 1 diabetes and healthy individuals. Diabetes Care. 2010;33:1529–35.
    • (2010) Diabetes Care , vol.33 , pp. 1529-1535
    • Gogitidze, J.N.1    Hedrington, M.S.2    Briscoe, V.J.3    Tate, D.B.4    Ertl, A.C.5    Davis, S.N.6
  • 45
    • 84901357044 scopus 로고    scopus 로고
    • Hypoglycemia and cardiac arrhythmia in patients with diabetes mellitus type 2
    • COI: 1:STN:280:DC%2BC2crnvVGqsg%3D%3D, PID: 24671665
    • Hanefeld M, Ganz X, Nolte C. Hypoglycemia and cardiac arrhythmia in patients with diabetes mellitus type 2. Herz. 2014;39:312–9.
    • (2014) Herz , vol.39 , pp. 312-319
    • Hanefeld, M.1    Ganz, X.2    Nolte, C.3
  • 46
    • 80052522584 scopus 로고    scopus 로고
    • Prognostic implications of glucose-lowering treatment in patients with acute myocardial infarction and diabetes: experiences from an extended follow-up of the Diabetes Mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) 2 Study
    • COI: 1:CAS:528:DC%2BC3MXlslWgtLo%3D, PID: 21359582
    • Mellbin LG, Malmberg K, Norhammar A, Wedel H, Ryden L. Prognostic implications of glucose-lowering treatment in patients with acute myocardial infarction and diabetes: experiences from an extended follow-up of the Diabetes Mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) 2 Study. Diabetologia. 2011;54:1308–17.
    • (2011) Diabetologia , vol.54 , pp. 1308-1317
    • Mellbin, L.G.1    Malmberg, K.2    Norhammar, A.3    Wedel, H.4    Ryden, L.5
  • 47
    • 0038051142 scopus 로고    scopus 로고
    • Sulfonylureas and cardiovascular effects: from experimental data to clinical use. Available data in humans and clinical applications
    • COI: 1:CAS:528:DC%2BD3sXms1yiu7k%3D, PID: 12909809
    • Riveline JP, Danchin N, Ledru F, Varroud-Vial M, Charpentier G. Sulfonylureas and cardiovascular effects: from experimental data to clinical use. Available data in humans and clinical applications. Diabetes Metab. 2003;29:207–22.
    • (2003) Diabetes Metab , vol.29 , pp. 207-222
    • Riveline, J.P.1    Danchin, N.2    Ledru, F.3    Varroud-Vial, M.4    Charpentier, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.