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Volumn 138, Issue 1, 2016, Pages 98-109

Phylogenetic analysis of multiple FISH markers in oral tongue squamous cell carcinoma suggests that a diverse distribution of copy number changes is associated with poor prognosis

(14)  Wangsa, Darawalee a,b   Chowdhury, Salim Akhter c,d   Ryott, Michael e   Gertz, E Michael f   Elmberger, Göran g   Auer, Gert b   Lundqvist, Elisabeth Åvall b,h   Küffer, Stefan i   Ströbel, Philipp i   Schäffer, Alejandro A f   Schwartz, Russell d,j   Munck Wikland, Eva b   Ried, Thomas a   Heselmeyer Haddad, Kerstin a  


Author keywords

FISH; genetic markers; HPV; oral tongue cancer; phylogenetic modeling

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GENOMIC DNA; PROTEIN P53; TUMOR MARKER;

EID: 84944276406     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29691     Document Type: Article
Times cited : (18)

References (52)
  • 1
    • 17644420688 scopus 로고    scopus 로고
    • Tongue and tonsil carcinoma: Increasing trends in the U.S. Population ages 20-44 years
    • Shiboski CH, Schmidt BL, Jordan RC., Tongue and tonsil carcinoma: Increasing trends in the U.S. population ages 20-44 years. Cancer 2005; 103: 1843-9.
    • (2005) Cancer , vol.103 , pp. 1843-1849
    • Shiboski, C.H.1    Schmidt, B.L.2    Jordan, R.C.3
  • 2
    • 84944281401 scopus 로고    scopus 로고
    • Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke
    • in press
    • Li R, Faden DL, Fakhry C, et al., Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke. Head Neck, in press.
    • Head Neck
    • Li, R.1    Faden, D.L.2    Fakhry, C.3
  • 3
    • 45849115806 scopus 로고    scopus 로고
    • Smokeless tobacco and cancer
    • Boffetta P, Hecht S, Gray N, et al., Smokeless tobacco and cancer. Lancet Oncol 2008; 9: 667-75.
    • (2008) Lancet Oncol , vol.9 , pp. 667-675
    • Boffetta, P.1    Hecht, S.2    Gray, N.3
  • 4
    • 84899135167 scopus 로고    scopus 로고
    • Alcohol consumption, cigarette smoking and the risk of subtypes of head-neck cancer: Results from the Netherlands Cohort Study
    • Maasland DH, van den Brandt PA, Kremer B, et al., Alcohol consumption, cigarette smoking and the risk of subtypes of head-neck cancer: Results from the Netherlands Cohort Study. BMC Cancer 2014; 14: 187
    • (2014) BMC Cancer , vol.14 , pp. 187
    • Maasland, D.H.1    Van Den Brandt, P.A.2    Kremer, B.3
  • 5
    • 83055180559 scopus 로고    scopus 로고
    • Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers
    • Ambatipudi S, Gerstung M, Pandey M, et al., Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers. Genes Chromosomes Cancer 2012; 51: 161-73.
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 161-173
    • Ambatipudi, S.1    Gerstung, M.2    Pandey, M.3
  • 6
    • 8644249908 scopus 로고    scopus 로고
    • Human papillomavirus is more common in base of tongue than in mobile tongue cancer and is a favorable prognostic factor in base of tongue cancer patients
    • Dahlgren L, Dahlstrand HM, Lindquist D, et al., Human papillomavirus is more common in base of tongue than in mobile tongue cancer and is a favorable prognostic factor in base of tongue cancer patients. Int J Cancer 2004; 112: 1015-9.
    • (2004) Int J Cancer , vol.112 , pp. 1015-1019
    • Dahlgren, L.1    Dahlstrand, H.M.2    Lindquist, D.3
  • 7
    • 36048972283 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization for detecting genomic alterations of cyclin D1 and p16 in oral squamous cell carcinomas
    • Uzawa N, Sonoda I, Myo K, et al., Fluorescence in situ hybridization for detecting genomic alterations of cyclin D1 and p16 in oral squamous cell carcinomas. Cancer 2007; 110: 2230-9.
    • (2007) Cancer , vol.110 , pp. 2230-2239
    • Uzawa, N.1    Sonoda, I.2    Myo, K.3
  • 8
    • 81255143454 scopus 로고    scopus 로고
    • Two distinct routes to oral cancer differing in genome instability and risk for cervical node metastasis
    • Bhattacharya A, Roy R, Snijders AM, et al., Two distinct routes to oral cancer differing in genome instability and risk for cervical node metastasis. Clin Cancer Res 2011; 17: 7024-34.
    • (2011) Clin Cancer Res , vol.17 , pp. 7024-7034
    • Bhattacharya, A.1    Roy, R.2    Snijders, A.M.3
  • 9
    • 77956393928 scopus 로고    scopus 로고
    • Understanding oral cancer in the genome era
    • Viet CT, Schmidt BL., Understanding oral cancer in the genome era. Head Neck 2010; 32: 1246-68.
    • (2010) Head Neck , vol.32 , pp. 1246-1268
    • Viet, C.T.1    Schmidt, B.L.2
  • 10
    • 0030892905 scopus 로고    scopus 로고
    • Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer
    • Soder AI, Hoare SF, Muir S, et al., Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer. Oncogene 1997; 14: 1013-21.
    • (1997) Oncogene , vol.14 , pp. 1013-1021
    • Soder, A.I.1    Hoare, S.F.2    Muir, S.3
  • 11
    • 0036131951 scopus 로고    scopus 로고
    • Chromosomal alterations during metastasis formation of head and neck squamous cell carcinoma
    • Bockmuhl U, Schluns K, Schmidt S, et al., Chromosomal alterations during metastasis formation of head and neck squamous cell carcinoma. Genes Chromosomes Cancer 2002; 33: 29-35.
    • (2002) Genes Chromosomes Cancer , vol.33 , pp. 29-35
    • Bockmuhl, U.1    Schluns, K.2    Schmidt, S.3
  • 12
    • 1542360069 scopus 로고    scopus 로고
    • OCGR array: An oral cancer genomic regional array for comparative genomic hybridization analysis
    • Garnis C, Campbell J, Zhang L, et al., OCGR array: An oral cancer genomic regional array for comparative genomic hybridization analysis. Oral Oncol 2004; 40: 511-9.
    • (2004) Oral Oncol , vol.40 , pp. 511-519
    • Garnis, C.1    Campbell, J.2    Zhang, L.3
  • 13
    • 84879917317 scopus 로고    scopus 로고
    • Phylogenetic analysis of multiprobe fluorescence in situ hybridization data from tumor cell populations
    • Chowdhury SA, Shackney SE, Heselmeyer-Haddad K, et al., Phylogenetic analysis of multiprobe fluorescence in situ hybridization data from tumor cell populations. Bioinformatics 2013; 29: I189-98.
    • (2013) Bioinformatics , vol.29 , pp. i189-i198
    • Chowdhury, S.A.1    Shackney, S.E.2    Heselmeyer-Haddad, K.3
  • 14
    • 84905483329 scopus 로고    scopus 로고
    • Algorithms to model single gene, single chromosome, and whole genome copy number changes jointly in tumor phylogenetics
    • Chowdhury SA, Shackney SE, Heselmeyer-Haddad K, et al., Algorithms to model single gene, single chromosome, and whole genome copy number changes jointly in tumor phylogenetics. PLoS Comput Biol 2014; 10: E1003740
    • (2014) PLoS Comput Biol , vol.10 , pp. e1003740
    • Chowdhury, S.A.1    Shackney, S.E.2    Heselmeyer-Haddad, K.3
  • 15
    • 74949101897 scopus 로고    scopus 로고
    • Inferring tumor progression from genomic heterogeneity
    • Navin N, Krasnitz A, Rodgers L, et al., Inferring tumor progression from genomic heterogeneity. Genome Res 2010; 20: 68-80.
    • (2010) Genome Res , vol.20 , pp. 68-80
    • Navin, N.1    Krasnitz, A.2    Rodgers, L.3
  • 16
    • 0032894615 scopus 로고    scopus 로고
    • Inferring tree models for oncogenesis from comparative genome hybridization data
    • Desper R, Jiang F, Kallioniemi OP, et al., Inferring tree models for oncogenesis from comparative genome hybridization data. J Comput Biol 1999; 6: 37-51.
    • (1999) J Comput Biol , vol.6 , pp. 37-51
    • Desper, R.1    Jiang, F.2    Kallioniemi, O.P.3
  • 17
    • 19544368329 scopus 로고    scopus 로고
    • Learning multiple evolutionary pathways from cross-sectional data
    • Beerenwinkel N, Rahnenfuhrer J, Daumer M, et al., Learning multiple evolutionary pathways from cross-sectional data. J Comput Biol 2005; 12: 584-98.
    • (2005) J Comput Biol , vol.12 , pp. 584-598
    • Beerenwinkel, N.1    Rahnenfuhrer, J.2    Daumer, M.3
  • 18
    • 84857475740 scopus 로고    scopus 로고
    • A mathematical methodology for determining the temporal order of pathway alterations arising during gliomagenesis
    • Cheng YK, Beroukhim R, Levine RL, et al., A mathematical methodology for determining the temporal order of pathway alterations arising during gliomagenesis. PLoS Comput Biol 2012; 8: E1002337.
    • (2012) PLoS Comput Biol , vol.8 , pp. e1002337
    • Cheng, Y.K.1    Beroukhim, R.2    Levine, R.L.3
  • 19
    • 0034919518 scopus 로고    scopus 로고
    • Distance-based reconstruction of tree models for oncogenesis
    • Desper R, Jiang F, Kallioniemi OP, et al., Distance-based reconstruction of tree models for oncogenesis. J Comput Biol 2000; 7: 789-803.
    • (2000) J Comput Biol , vol.7 , pp. 789-803
    • Desper, R.1    Jiang, F.2    Kallioniemi, O.P.3
  • 20
    • 0028960673 scopus 로고
    • Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck
    • Brennan JA, Boyle JO, Koch WM, et al., Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. N Engl J Med 1995; 332: 712-7.
    • (1995) N Engl J Med , vol.332 , pp. 712-717
    • Brennan, J.A.1    Boyle, J.O.2    Koch, W.M.3
  • 21
    • 34248334736 scopus 로고    scopus 로고
    • American Joint Committee on Cancer., American Cancer Society
    • 6th ed. New York: Springer, xiv, 421 p
    • Greene FL, American Joint Committee on Cancer., American Cancer Society. AJCC cancer staging manual, 6th ed. New York: Springer, 2002. xiv, 421 p.
    • (2002) AJCC cancer staging manual
    • Greene, F.L.1
  • 22
    • 84922438928 scopus 로고    scopus 로고
    • Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis
    • Heselmeyer-Haddad KM, Berroa Garcia LY, et al., Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis. Am J Pathol 2014; 184: 2671-86.
    • (2014) Am J Pathol , vol.184 , pp. 2671-2686
    • Heselmeyer-Haddad, K.M.1    Berroa Garcia, L.Y.2
  • 23
    • 84868214754 scopus 로고    scopus 로고
    • Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression
    • Heselmeyer-Haddad K, Berroa Garcia LY, Bradley A, et al., Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression. Am J Pathol 2012; 181: 1807-22.
    • (2012) Am J Pathol , vol.181 , pp. 1807-1822
    • Heselmeyer-Haddad, K.1    Berroa Garcia, L.Y.2    Bradley, A.3
  • 25
    • 84898803843 scopus 로고    scopus 로고
    • Human papillomavirus prevalence is high in oral samples of patients with tonsillar and base of tongue cancer
    • Nordfors C, Vlastos A, Du J, et al., Human papillomavirus prevalence is high in oral samples of patients with tonsillar and base of tongue cancer. Oral Oncol 2014; 50: 491-7.
    • (2014) Oral Oncol , vol.50 , pp. 491-497
    • Nordfors, C.1    Vlastos, A.2    Du, J.3
  • 26
    • 73549092920 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization markers for prediction of cervical lymph node metastases
    • Wangsa D, Heselmeyer-Haddad K, Ried P, et al., Fluorescence in situ hybridization markers for prediction of cervical lymph node metastases. Am J Pathol 2009; 175: 2637-45.
    • (2009) Am J Pathol , vol.175 , pp. 2637-2645
    • Wangsa, D.1    Heselmeyer-Haddad, K.2    Ried, P.3
  • 27
    • 84856257263 scopus 로고    scopus 로고
    • P53 Expression as a marker of microinvasion in oral squamous cell carcinoma
    • Heah KG, Hassan MI, Huat SC., p53 Expression as a marker of microinvasion in oral squamous cell carcinoma. Asian Pac J Cancer Prev 2011; 12: 1017-22.
    • (2011) Asian Pac J Cancer Prev , vol.12 , pp. 1017-1022
    • Heah, K.G.1    Hassan, M.I.2    Huat, S.C.3
  • 28
    • 0033990714 scopus 로고    scopus 로고
    • Clinical relevance of ERBB-1 and -2 oncogenes in oral carcinomas
    • Werkmeister R, Brandt B, Joos U., Clinical relevance of erbB-1 and -2 oncogenes in oral carcinomas. Oral Oncol 2000; 36: 100-5.
    • (2000) Oral Oncol , vol.36 , pp. 100-105
    • Werkmeister, R.1    Brandt, B.2    Joos, U.3
  • 29
    • 76649128993 scopus 로고    scopus 로고
    • Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype
    • Park SY, Gonen M, Kim HJ, et al., Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. J Clin Invest 2010; 120: 636-44.
    • (2010) J Clin Invest , vol.120 , pp. 636-644
    • Park, S.Y.1    Gonen, M.2    Kim, H.J.3
  • 30
    • 0035024922 scopus 로고    scopus 로고
    • Multivariate analyses of genomic imbalances in solid tumors reveal distinct and converging pathways of karyotypic evolution
    • Hoglund M, Gisselsson D, Mandahl N, et al., Multivariate analyses of genomic imbalances in solid tumors reveal distinct and converging pathways of karyotypic evolution. Genes Chromosomes Cancer 2001; 31: 156-71.
    • (2001) Genes Chromosomes Cancer , vol.31 , pp. 156-171
    • Hoglund, M.1    Gisselsson, D.2    Mandahl, N.3
  • 31
    • 0031023529 scopus 로고    scopus 로고
    • Amplification of cyclin D1 in squamous cell carcinoma of the head and neck and the prognostic value of chromosomal abnormalities and cyclin D1 overexpression
    • Akervall JA, Michalides RJ, Mineta H, et al., Amplification of cyclin D1 in squamous cell carcinoma of the head and neck and the prognostic value of chromosomal abnormalities and cyclin D1 overexpression. Cancer 1997; 79: 380-9.
    • (1997) Cancer , vol.79 , pp. 380-389
    • Akervall, J.A.1    Michalides, R.J.2    Mineta, H.3
  • 32
    • 0032589742 scopus 로고    scopus 로고
    • Cyclin D1 and p16INK4A expression predict reduced survival in carcinoma of the anterior tongue
    • Bova RJ, Quinn DI, Nankervis JS, et al., Cyclin D1 and p16INK4A expression predict reduced survival in carcinoma of the anterior tongue. Clin Cancer Res 1999; 5: 2810-9.
    • (1999) Clin Cancer Res , vol.5 , pp. 2810-2819
    • Bova, R.J.1    Quinn, D.I.2    Nankervis, J.S.3
  • 33
    • 0035976044 scopus 로고    scopus 로고
    • Cyclin D1 amplification correlates with early recurrence of squamous cell carcinoma of the tongue
    • Fujii M, Ishiguro R, Yamashita T, et al., Cyclin D1 amplification correlates with early recurrence of squamous cell carcinoma of the tongue. Cancer Lett 2001; 172: 187-92.
    • (2001) Cancer Lett , vol.172 , pp. 187-192
    • Fujii, M.1    Ishiguro, R.2    Yamashita, T.3
  • 34
    • 50649125210 scopus 로고    scopus 로고
    • Presence of dominant negative mutation of TP53 is a risk of early recurrence in oral cancer
    • Hassan NM, Tada M, Hamada J, et al., Presence of dominant negative mutation of TP53 is a risk of early recurrence in oral cancer. Cancer Lett 2008; 270: 108-19.
    • (2008) Cancer Lett , vol.270 , pp. 108-119
    • Hassan, N.M.1    Tada, M.2    Hamada, J.3
  • 35
    • 80052962062 scopus 로고    scopus 로고
    • CCND1 amplification and protein overexpression in oral squamous cell carcinoma of young patients
    • Kaminagakura E, Werneck da Cunha I, Soares FA, et al., CCND1 amplification and protein overexpression in oral squamous cell carcinoma of young patients. Head Neck 2011; 33: 1413-9.
    • (2011) Head Neck , vol.33 , pp. 1413-1419
    • Kaminagakura, E.1    Werneck da Cunha, I.2    Soares, F.A.3
  • 36
    • 0030919581 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 indicates a poor prognosis in squamous cell carcinoma of the head and neck
    • Michalides RJ, van Veelen NM, Kristel PM, et al., Overexpression of cyclin D1 indicates a poor prognosis in squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 1997; 123: 497-502.
    • (1997) Arch Otolaryngol Head Neck Surg , vol.123 , pp. 497-502
    • Michalides, R.J.1    Van Veelen, N.M.2    Kristel, P.M.3
  • 37
    • 0037110672 scopus 로고    scopus 로고
    • Potential marker of oral squamous cell carcinoma aggressiveness detected by fluorescence in situ hybridization in fine-needle aspiration biopsies
    • Miyamoto R, Uzawa N, Nagaoka S, et al., Potential marker of oral squamous cell carcinoma aggressiveness detected by fluorescence in situ hybridization in fine-needle aspiration biopsies. Cancer 2002; 95: 2152-9.
    • (2002) Cancer , vol.95 , pp. 2152-2159
    • Miyamoto, R.1    Uzawa, N.2    Nagaoka, S.3
  • 38
    • 29144536859 scopus 로고    scopus 로고
    • Cyclin D1 gene numerical aberration is a predictive marker for occult cervical lymph node metastasis in TNM Stage I and II squamous cell carcinoma of the oral cavity
    • Myo K, Uzawa N, Miyamoto R, et al., Cyclin D1 gene numerical aberration is a predictive marker for occult cervical lymph node metastasis in TNM Stage I and II squamous cell carcinoma of the oral cavity. Cancer 2005; 104: 2709-16.
    • (2005) Cancer , vol.104 , pp. 2709-2716
    • Myo, K.1    Uzawa, N.2    Miyamoto, R.3
  • 39
    • 80053347280 scopus 로고    scopus 로고
    • EGFR gene copy number alteration is a better prognostic indicator than protein overexpression in oral tongue squamous cell carcinomas
    • Nakata Y, Uzawa N, Takahashi K, et al., EGFR gene copy number alteration is a better prognostic indicator than protein overexpression in oral tongue squamous cell carcinomas. Eur J Cancer 2011; 47: 2364-72.
    • (2011) Eur J Cancer , vol.47 , pp. 2364-2372
    • Nakata, Y.1    Uzawa, N.2    Takahashi, K.3
  • 40
    • 70350312957 scopus 로고    scopus 로고
    • Role of TP53 in the progression of pre-malignant and malignant oral mucosal lesions. A follow-up study of 144 patients
    • Ogmundsdottir HM, Bjornsson J, Holbrook WP., Role of TP53 in the progression of pre-malignant and malignant oral mucosal lesions. A follow-up study of 144 patients. J Oral Pathol Med 2009; 38: 565-71.
    • (2009) J Oral Pathol Med , vol.38 , pp. 565-571
    • Ogmundsdottir, H.M.1    Bjornsson, J.2    Holbrook, W.P.3
  • 41
    • 33746094622 scopus 로고    scopus 로고
    • Carcinoma of tongue and the buccal mucosa represent different biological subentities of the oral carcinoma
    • Sathyan KM, Sailasree R, Jayasurya R, et al., Carcinoma of tongue and the buccal mucosa represent different biological subentities of the oral carcinoma. J Cancer Res Clin Oncol 2006; 132: 601-9.
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 601-609
    • Sathyan, K.M.1    Sailasree, R.2    Jayasurya, R.3
  • 42
    • 33745671633 scopus 로고    scopus 로고
    • Activation of ERK1/2 and cyclin D1 expression in oral tongue squamous cell carcinomas: Relationship between clinicopathological appearances and cell proliferation
    • Wang L, Liu T, Nishioka M, et al., Activation of ERK1/2 and cyclin D1 expression in oral tongue squamous cell carcinomas: Relationship between clinicopathological appearances and cell proliferation. Oral Oncol 2006; 42: 625-31.
    • (2006) Oral Oncol , vol.42 , pp. 625-631
    • Wang, L.1    Liu, T.2    Nishioka, M.3
  • 43
    • 10944250660 scopus 로고    scopus 로고
    • Genomic gain of the epidermal growth factor receptor harboring band 7p12 is part of a complex pattern of genomic imbalances in oral squamous cell carcinomas
    • Gebhart E, Ries J, Wiltfang J, et al., Genomic gain of the epidermal growth factor receptor harboring band 7p12 is part of a complex pattern of genomic imbalances in oral squamous cell carcinomas. Arch Med Res 2004; 35: 385-94.
    • (2004) Arch Med Res , vol.35 , pp. 385-394
    • Gebhart, E.1    Ries, J.2    Wiltfang, J.3
  • 44
    • 67649798606 scopus 로고    scopus 로고
    • Evolutionary theory of cancer
    • Attolini CS, Michor F., Evolutionary theory of cancer. Ann N Y Acad Sci 2009; 1168: 23-51.
    • (2009) Ann N Y Acad Sci , vol.1168 , pp. 23-51
    • Attolini, C.S.1    Michor, F.2
  • 45
    • 78549262724 scopus 로고    scopus 로고
    • Patient-oriented gene set analysis for cancer mutation data
    • Boca SM, Kinzler KW, Velculescu VE, et al., Patient-oriented gene set analysis for cancer mutation data. Genome Biol 2010; 11: R112.
    • (2010) Genome Biol , vol.11 , pp. R112
    • Boca, S.M.1    Kinzler, K.W.2    Velculescu, V.E.3
  • 46
    • 0033614998 scopus 로고    scopus 로고
    • Creation of human tumour cells with defined genetic elements
    • Hahn WC, Counter CM, Lundberg AS, et al., Creation of human tumour cells with defined genetic elements. Nature 1999; 400: 464-8.
    • (1999) Nature , vol.400 , pp. 464-468
    • Hahn, W.C.1    Counter, C.M.2    Lundberg, A.S.3
  • 47
    • 80055103856 scopus 로고    scopus 로고
    • The temporal order of genetic and pathway alterations in tumorigenesis
    • Gerstung M, Eriksson N, Lin J, et al., The temporal order of genetic and pathway alterations in tumorigenesis. PLoS One 2011; 6: E27136
    • (2011) PLoS One , vol.6 , pp. e27136
    • Gerstung, M.1    Eriksson, N.2    Lin, J.3
  • 48
    • 84856532705 scopus 로고    scopus 로고
    • De novo discovery of mutated driver pathways in cancer
    • Vandin F, Upfal E, Raphael BJ., De novo discovery of mutated driver pathways in cancer. Genome Res 2012; 22: 375-85.
    • (2012) Genome Res , vol.22 , pp. 375-385
    • Vandin, F.1    Upfal, E.2    Raphael, B.J.3
  • 49
    • 77949446630 scopus 로고    scopus 로고
    • Automated network analysis identifies core pathways in glioblastoma
    • Cerami E, Demir E, Schultz N, et al., Automated network analysis identifies core pathways in glioblastoma. PLoS One 2010; 5: E8918
    • (2010) PLoS One , vol.5 , pp. e8918
    • Cerami, E.1    Demir, E.2    Schultz, N.3
  • 50
    • 67650737329 scopus 로고    scopus 로고
    • Genetic classification of oral and oropharyngeal carcinomas identifies subgroups with a different prognosis
    • Smeets SJ, Brakenhoff RH, Ylstra B, et al., Genetic classification of oral and oropharyngeal carcinomas identifies subgroups with a different prognosis. Cell Oncol 2009; 31: 291-300.
    • (2009) Cell Oncol , vol.31 , pp. 291-300
    • Smeets, S.J.1    Brakenhoff, R.H.2    Ylstra, B.3
  • 51
    • 20544465379 scopus 로고    scopus 로고
    • Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma
    • Snijders AM, Schmidt BL, Fridlyand J, et al., Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene 2005; 24: 4232-42.
    • (2005) Oncogene , vol.24 , pp. 4232-4242
    • Snijders, A.M.1    Schmidt, B.L.2    Fridlyand, J.3
  • 52
    • 0030882091 scopus 로고    scopus 로고
    • P53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability
    • Liloglou T, Scholes AG, Spandidos DA, et al., p53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability. Cancer Res 1997; 57: 4070-4.
    • (1997) Cancer Res , vol.57 , pp. 4070-4074
    • Liloglou, T.1    Scholes, A.G.2    Spandidos, D.A.3


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