Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs

Cell Host and Microbe

Volumn 18, Issue 4, 2015, Pages 433-444

  Das, Sujaan ^a,f   Hertrich, Nadine ^b   Perrin, Abigail J ^c   Withers Martinez, Chrislaine ^a   Collins, Christine R ^a   Jones, Matthew L ^a   Watermeyer, Jean M ^d   Fobes, Elmar T ^b   Martin, Stephen R ^a   Saibil, Helen R ^d   Wright, Gavin J ^c   Treeck, Moritz ^a   Epp, Christian ^b   Blackman, Michael J ^a,e  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d UNIVERSITY OF LONDON   (United Kingdom)

^e LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MEROZOITE SURFACE PROTEIN 1; SPECTRIN; PROTEIN BINDING; PROTOZOAL PROTEIN; SUB1 PROTEIN, TOXOPLASMA GONDII; SUBTILISIN;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOSKELETON; EPISOME; ERYTHROCYTE; GENE MUTATION; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MEROZOITE; NONHUMAN; PARASITE DEVELOPMENT; PARASITE VIABILITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN PROCESSING; PROTEIN SECONDARY STRUCTURE; TRANSGENE; BIOLOGICAL MODEL; CHEMISTRY; ENZYMOLOGY; HOST PATHOGEN INTERACTION; METABOLISM; PARASITOLOGY; PHYSIOLOGY; PLASMODIUM FALCIPARUM; PROTEIN CONFORMATION; PROTEIN DEGRADATION;

ERYTHROCYTES; HOST-PATHOGEN INTERACTIONS; HUMANS; MEROZOITE SURFACE PROTEIN 1; MEROZOITES; MODELS, BIOLOGICAL; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; PROTOZOAN PROTEINS; SPECTRIN; SUBTILISINS;

EID: 84944246344     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2015.09.007     Document Type: Article

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