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Volumn 132, Issue 5, 2015, Pages 345-354

The 'disconnect' between initial judgments of lamotrigine vs. its real-world effectiveness in managing bipolar disorder. A tale with wider ramifications

Author keywords

Bipolar disorder; Depression; Lamotrigine; Randomized controlled trial; Review

Indexed keywords

CARBAMAZEPINE; LAMOTRIGINE; LITHIUM; ANTICONVULSIVE AGENT; TRIAZINE DERIVATIVE;

EID: 84944173992     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/acps.12427     Document Type: Article
Times cited : (12)

References (32)
  • 1
    • 0032923291 scopus 로고    scopus 로고
    • Treatment research at the crossroads: the scientific interface of clinical trials and effectiveness research
    • Wells KB. Treatment research at the crossroads: the scientific interface of clinical trials and effectiveness research. Am J Psychiatry 1999;156:5-10.
    • (1999) Am J Psychiatry , vol.156 , pp. 5-10
    • Wells, K.B.1
  • 2
    • 0029781092 scopus 로고    scopus 로고
    • Antidepressant effects of lamotrigine in rapid cycling bipolar disorder (letter)
    • Calabrese JR, Fatemi SH, Woyshville MJ. Antidepressant effects of lamotrigine in rapid cycling bipolar disorder (letter). Am J Psychiatry 1996;153:1236.
    • (1996) Am J Psychiatry , vol.153 , pp. 1236
    • Calabrese, J.R.1    Fatemi, S.H.2    Woyshville, M.J.3
  • 4
    • 0033004838 scopus 로고    scopus 로고
    • A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group
    • Calabrese JR, Bowden CL, Sachs GS et al. A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. J Clin Psychiatry 1999;60:79-88.
    • (1999) J Clin Psychiatry , vol.60 , pp. 79-88
    • Calabrese, J.R.1    Bowden, C.L.2    Sachs, G.S.3
  • 5
    • 13444271031 scopus 로고    scopus 로고
    • Efficacy of lamotrigine in bipolar disorder: preliminary data
    • Manji HK, Bowden C, Belmaker R, eds. Washington, DC: American Psychiatric Press
    • Calabrese JR, Bowden CL, Mcelroy SL et al. Efficacy of lamotrigine in bipolar disorder: preliminary data. In: Manji HK, Bowden C, Belmaker R, eds. Bipolar medications: mechanisms of action. Washington, DC: American Psychiatric Press, 1997:367-374.
    • (1997) Bipolar medications: mechanisms of action , pp. 367-374
    • Calabrese, J.R.1    Bowden, C.L.2    Mcelroy, S.L.3
  • 6
    • 0345590563 scopus 로고    scopus 로고
    • Lamotrigine in treatment - refractory bipolar disorder
    • Cookson J, Kundu S, Anderson J et al. Lamotrigine in treatment - refractory bipolar disorder. J Psychopharmacol 1996;10(suppl):A39.
    • (1996) J Psychopharmacol , vol.10 , pp. A39
    • Cookson, J.1    Kundu, S.2    Anderson, J.3
  • 7
    • 0033561206 scopus 로고    scopus 로고
    • The efficacy of lamotrigine in rapid cycling and non-rapid cycling patients with bipolar disorder
    • Bowden CL, Calabrese JR, Mcelroy SL et al. The efficacy of lamotrigine in rapid cycling and non-rapid cycling patients with bipolar disorder. Biol Psychiatry 1999;45:953-958.
    • (1999) Biol Psychiatry , vol.45 , pp. 953-958
    • Bowden, C.L.1    Calabrese, J.R.2    Mcelroy, S.L.3
  • 8
    • 0033697737 scopus 로고    scopus 로고
    • A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders
    • Frye MA, Ketter TA, Kimbrell TA et al. A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders. J Clin Psychopharmacol 2000;20:607-614.
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 607-614
    • Frye, M.A.1    Ketter, T.A.2    Kimbrell, T.A.3
  • 9
    • 0036468685 scopus 로고    scopus 로고
    • Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders
    • Obrocea GV, Dunn RM, Frye MA et al. Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders. Biol Psychiatry 2002;51:253-260.
    • (2002) Biol Psychiatry , vol.51 , pp. 253-260
    • Obrocea, G.V.1    Dunn, R.M.2    Frye, M.A.3
  • 10
    • 54049104414 scopus 로고    scopus 로고
    • A single blind comparison of lithium and lamotrigine for the treatment of bipolar II depression
    • Suppes T, Marangell LB, Bernstein IH et al. A single blind comparison of lithium and lamotrigine for the treatment of bipolar II depression. J Affect Disord 2008;111:334-343.
    • (2008) J Affect Disord , vol.111 , pp. 334-343
    • Suppes, T.1    Marangell, L.B.2    Bernstein, I.H.3
  • 11
    • 62649121952 scopus 로고    scopus 로고
    • Efficacy and safety of lamotrigine as add-on treatment to lithium in bipolar depression: a multicenter, double-blind, placebo-controlled trial
    • van der Loos ML, Mulder PG, Hartong EG et al. Efficacy and safety of lamotrigine as add-on treatment to lithium in bipolar depression: a multicenter, double-blind, placebo-controlled trial. J Clin Psychiatry 2009;70:223-231.
    • (2009) J Clin Psychiatry , vol.70 , pp. 223-231
    • van der Loos, M.L.1    Mulder, P.G.2    Hartong, E.G.3
  • 12
    • 79951483393 scopus 로고    scopus 로고
    • Long-term outcome of bipolar depressed patients receiving lamotrigine as add-on to lithium with the possibility of the addition of paroxetine in nonresponders: a randomized, placebo-controlled trial with a novel design
    • van der Loos ML, Mulder P, Hartong EG et al. Long-term outcome of bipolar depressed patients receiving lamotrigine as add-on to lithium with the possibility of the addition of paroxetine in nonresponders: a randomized, placebo-controlled trial with a novel design. Bipolar Disord 2011;13:111-117.
    • (2011) Bipolar Disord , vol.13 , pp. 111-117
    • van der Loos, M.L.1    Mulder, P.2    Hartong, E.G.3
  • 13
    • 43149119463 scopus 로고    scopus 로고
    • Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trials
    • Calabrese JR, Huffman RF, White RL et al. Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trials. Bipolar Disord 2008;10:323-333.
    • (2008) Bipolar Disord , vol.10 , pp. 323-333
    • Calabrese, J.R.1    Huffman, R.F.2    White, R.L.3
  • 14
    • 58149374246 scopus 로고    scopus 로고
    • Lamotrigine for treatment of bipolar depression: independent meta-analysis and meta-regression of individual patient data from five randomised trials
    • Geddes JR, Calabrese JR, Goodwin GM. Lamotrigine for treatment of bipolar depression: independent meta-analysis and meta-regression of individual patient data from five randomised trials. Br J Psychiatry 2009;194:4-9.
    • (2009) Br J Psychiatry , vol.194 , pp. 4-9
    • Geddes, J.R.1    Calabrese, J.R.2    Goodwin, G.M.3
  • 15
    • 50649090996 scopus 로고    scopus 로고
    • Effectiveness of lamotrigine in bipolar disorder in a clinical setting
    • Ketter TA, Brooks JO, Hoblyn JC et al. Effectiveness of lamotrigine in bipolar disorder in a clinical setting. J Psychiatr Res 2008;43:13-23.
    • (2008) J Psychiatr Res , vol.43 , pp. 13-23
    • Ketter, T.A.1    Brooks, J.O.2    Hoblyn, J.C.3
  • 16
    • 0042911456 scopus 로고    scopus 로고
    • Latest maintenance data on lamotrigine in bipolar disorder
    • Calabrese JR, Vieta E, Shelton MD. Latest maintenance data on lamotrigine in bipolar disorder. Eur Neuropsychopharmacol 2003;13(suppl 2):S 57-S 66.
    • (2003) Eur Neuropsychopharmacol , vol.13 , pp. S 57-S 66
    • Calabrese, J.R.1    Vieta, E.2    Shelton, M.D.3
  • 17
    • 0037385145 scopus 로고    scopus 로고
    • A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder
    • Bowden CL, Calabrese JR, Sachs G et al. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch Gen Psychiatry 2003;60:392-400.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 392-400
    • Bowden, C.L.1    Calabrese, J.R.2    Sachs, G.3
  • 18
    • 2342540409 scopus 로고    scopus 로고
    • A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder
    • Goodwin GM, Bowden CL, Calabrese JR et al. A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder. J Clin Psychiatry 2004;65:432-441.
    • (2004) J Clin Psychiatry , vol.65 , pp. 432-441
    • Goodwin, G.M.1    Bowden, C.L.2    Calabrese, J.R.3
  • 19
    • 77955004373 scopus 로고    scopus 로고
    • Efficacy and safety of two treatment algorithms in bipolar depression consisting of a combination of lithium, lamotrigine or placebo and paroxetine
    • van der Loos MLM, Mulder P, Hartong EGTM et al. Efficacy and safety of two treatment algorithms in bipolar depression consisting of a combination of lithium, lamotrigine or placebo and paroxetine. Acta Psychiatr Scand 2010;122:246-254.
    • (2010) Acta Psychiatr Scand , vol.122 , pp. 246-254
    • van der Loos, M.L.M.1    Mulder, P.2    Hartong, E.G.T.M.3
  • 20
    • 77955672759 scopus 로고    scopus 로고
    • Lamotrigine versus lithium as maintenance treatment in bipolar I disorder: an open, randomized effectiveness study mimicking clinical practice. The 6th trial of the Danish University Antidepressant Group (DUAG-6)
    • Licht RW, Nielson JN, Gram LF et al. Lamotrigine versus lithium as maintenance treatment in bipolar I disorder: an open, randomized effectiveness study mimicking clinical practice. The 6th trial of the Danish University Antidepressant Group (DUAG-6). Bipolar Disord 2010;12:483-493.
    • (2010) Bipolar Disord , vol.12 , pp. 483-493
    • Licht, R.W.1    Nielson, J.N.2    Gram, L.F.3
  • 21
    • 15744367776 scopus 로고    scopus 로고
    • New data on the use of lithium, divalproate, and lamotrigine in rapid cycling bipolar disorder
    • Calabrese JR, Rapport DJ, Youngstrom EA et al. New data on the use of lithium, divalproate, and lamotrigine in rapid cycling bipolar disorder. Eur Psychiatry 2005;20:92-95.
    • (2005) Eur Psychiatry , vol.20 , pp. 92-95
    • Calabrese, J.R.1    Rapport, D.J.2    Youngstrom, E.A.3
  • 22
    • 0033696203 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. Lamictal 614 Study Group
    • Calabrese JR, Suppes T, Bowden CL et al. A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. Lamictal 614 Study Group. J Clin Psychiatry 2000;61:841-850.
    • (2000) J Clin Psychiatry , vol.61 , pp. 841-850
    • Calabrese, J.R.1    Suppes, T.2    Bowden, C.L.3
  • 23
    • 34249876743 scopus 로고    scopus 로고
    • Effectiveness of mood stabilizers and antipsychotics in the maintenance phase of bipolar disorder: a systematic review of randomized controlled trials
    • Smith LA, Cornelius V, Warnock A et al. Effectiveness of mood stabilizers and antipsychotics in the maintenance phase of bipolar disorder: a systematic review of randomized controlled trials. Bipolar Disord 2007;9:394-412.
    • (2007) Bipolar Disord , vol.9 , pp. 394-412
    • Smith, L.A.1    Cornelius, V.2    Warnock, A.3
  • 24
    • 85046912607 scopus 로고    scopus 로고
    • A systematic review and economic model of the clinical effectiveness and cost effectiveness of interventions for preventing relapse in people with bipolar disorder
    • Soares-Weiser K, Bravo Vergel Y, Beynon S et al. A systematic review and economic model of the clinical effectiveness and cost effectiveness of interventions for preventing relapse in people with bipolar disorder. Health Technol Assess 2007;11:1-6.
    • (2007) Health Technol Assess , vol.11 , pp. 1-6
    • Soares-Weiser, K.1    Bravo Vergel, Y.2    Beynon, S.3
  • 25
    • 84867444529 scopus 로고    scopus 로고
    • Lamotrigine vs. lamotrigine plus divalproex in randomized, placebo-controlled maintenance treatment for bipolar depression
    • Bowden CL, Singh V, Weisler R et al. Lamotrigine vs. lamotrigine plus divalproex in randomized, placebo-controlled maintenance treatment for bipolar depression. Acta Psychiatr Scand 2012;126:342-350.
    • (2012) Acta Psychiatr Scand , vol.126 , pp. 342-350
    • Bowden, C.L.1    Singh, V.2    Weisler, R.3
  • 26
    • 84896732294 scopus 로고    scopus 로고
    • The impact of being newly diagnosed with a bipolar disorder and the short-term outcome of disorder-specific management
    • Parker G, Graham RK, Fletcher K et al. The impact of being newly diagnosed with a bipolar disorder and the short-term outcome of disorder-specific management. Bipolar Disord 2014;16:172-179.
    • (2014) Bipolar Disord , vol.16 , pp. 172-179
    • Parker, G.1    Graham, R.K.2    Fletcher, K.3
  • 29
    • 62649137056 scopus 로고    scopus 로고
    • Lamotrigine in bipolar disorder: results of a mirror-image evaluation using the NIMH Lifechart-Methodology
    • Born C, Bernhard B, Dittmann S et al. Lamotrigine in bipolar disorder: results of a mirror-image evaluation using the NIMH Lifechart-Methodology. J Affect Disord 2009;115:241-245.
    • (2009) J Affect Disord , vol.115 , pp. 241-245
    • Born, C.1    Bernhard, B.2    Dittmann, S.3
  • 30
    • 36849045846 scopus 로고    scopus 로고
    • Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder
    • Goldberg JF, Bowden CL, Calabrese JR et al. Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder. Biol Psychiatry 2008;63:125-130.
    • (2008) Biol Psychiatry , vol.63 , pp. 125-130
    • Goldberg, J.F.1    Bowden, C.L.2    Calabrese, J.R.3
  • 31
    • 73449112663 scopus 로고    scopus 로고
    • Antidepressant drug effects and depression severity: a patient-level meta-analysis
    • Fournier JC, Derubeis RJ, Hollon SD et al. Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA 2010;303:47-53.
    • (2010) JAMA , vol.303 , pp. 47-53
    • Fournier, J.C.1    Derubeis, R.J.2    Hollon, S.D.3
  • 32
    • 0030768193 scopus 로고    scopus 로고
    • Putting trials on trial - the costs and consequences of small trials in depression: a systematic review of methodology
    • Hotopf M, Lewis G, Normand C. Putting trials on trial - the costs and consequences of small trials in depression: a systematic review of methodology. J Epidemiol Community Health 1997;51:354-358.
    • (1997) J Epidemiol Community Health , vol.51 , pp. 354-358
    • Hotopf, M.1    Lewis, G.2    Normand, C.3


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