메뉴 건너뛰기




Volumn 38, Issue 5, 2015, Pages 341-352

MYCN concurrence with SAHA-induced cell death in human neuroblastoma cells

Author keywords

MYCN; Neuroblastoma; SAHA

Indexed keywords

MESSENGER RNA; VORINOSTAT; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; MYCN PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN;

EID: 84944172752     PISSN: 22113428     EISSN: 22113436     Source Type: Journal    
DOI: 10.1007/s13402-015-0233-9     Document Type: Article
Times cited : (18)

References (43)
  • 1
    • 77953523121 scopus 로고    scopus 로고
    • Recent advances in neuroblastoma
    • COI: 1:CAS:528:DC%2BC3cXnsV2htr0%3D
    • J.M. Maris, Recent advances in neuroblastoma. N. Eng. J. Med. 362, 2202–2211 (2010)
    • (2010) N. Eng. J. Med. , vol.362 , pp. 2202-2211
    • Maris, J.M.1
  • 2
    • 84914165155 scopus 로고    scopus 로고
    • Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients
    • COI: 1:CAS:528:DC%2BC2cXhslOrtrfK
    • A. Bandino, D. Geerts, J. Koster, A.S. Bachmann, Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients. Cell. Oncol. 37, 387–398 (2014)
    • (2014) Cell. Oncol. , vol.37 , pp. 387-398
    • Bandino, A.1    Geerts, D.2    Koster, J.3    Bachmann, A.S.4
  • 3
    • 0037767937 scopus 로고    scopus 로고
    • A role for distinct cell types in determining malignancy in human neuroblastoma cell lines and tumors
    • COI: 1:CAS:528:DC%2BD3sXls1Cnsbo%3D, PID: 12880957
    • R.A. Ross, J.L. Biedler, B.A. Spengler, A role for distinct cell types in determining malignancy in human neuroblastoma cell lines and tumors. Cancer Lett. 197, 35–39 (2003)
    • (2003) Cancer Lett. , vol.197 , pp. 35-39
    • Ross, R.A.1    Biedler, J.L.2    Spengler, B.A.3
  • 8
    • 84890591387 scopus 로고    scopus 로고
    • MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin
    • S. Gherardi, E. Valli, D. Erriquez, G. Perini, MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin. Front. Oncol. 3, 1–8 (2013)
    • (2013) Front. Oncol. , vol.3 , pp. 1-8
    • Gherardi, S.1    Valli, E.2    Erriquez, D.3    Perini, G.4
  • 9
    • 32644454031 scopus 로고    scopus 로고
    • N-myc functions in transcription and development
    • COI: 1:CAS:528:DC%2BD28XhsVGqt7o%3D
    • P.J. Hurlin, N-myc functions in transcription and development. Birth Defects Res. 75, 340–352 (2005)
    • (2005) Birth Defects Res. , vol.75 , pp. 340-352
    • Hurlin, P.J.1
  • 11
    • 77952523404 scopus 로고    scopus 로고
    • MYCN oncoprotein targets and their therapeutic potential
    • COI: 1:CAS:528:DC%2BC3cXlvVaqsL0%3D, PID: 20153925
    • E. Bell, L. Chen, T. Liu, G.M. Marshall, J. Lunec, D.A. Tweddle, MYCN oncoprotein targets and their therapeutic potential. Cancer Lett. 293, 144–157 (2010)
    • (2010) Cancer Lett. , vol.293 , pp. 144-157
    • Bell, E.1    Chen, L.2    Liu, T.3    Marshall, G.M.4    Lunec, J.5    Tweddle, D.A.6
  • 14
    • 84857140530 scopus 로고    scopus 로고
    • Histone deacetylase inhibition induces apoptosis and autophagy in human neuroblastoma cells
    • COI: 1:CAS:528:DC%2BC38XjtVOlsbk%3D, PID: 22186300
    • R. Francisco, A. Pérez-Perarnau, C. Cortés, J. Gil, A. Tauler, S. Ambrosio, Histone deacetylase inhibition induces apoptosis and autophagy in human neuroblastoma cells. Cancer Lett. 318, 42–52 (2012)
    • (2012) Cancer Lett. , vol.318 , pp. 42-52
    • Francisco, R.1    Pérez-Perarnau, A.2    Cortés, C.3    Gil, J.4    Tauler, A.5    Ambrosio, S.6
  • 16
    • 64249143717 scopus 로고    scopus 로고
    • Targeting histone deacetylases in neuroblastoma
    • COI: 1:CAS:528:DC%2BD1MXjvVOnu7c%3D, PID: 19199971
    • O. Witt, H.E. Deubzer, M. Lodrini, T. Milde, I. Oehme, Targeting histone deacetylases in neuroblastoma. Curr. Pharm. Des. 15, 436–447 (2009)
    • (2009) Curr. Pharm. Des. , vol.15 , pp. 436-447
    • Witt, O.1    Deubzer, H.E.2    Lodrini, M.3    Milde, T.4    Oehme, I.5
  • 17
    • 0035328528 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor, CBHA, inhibits growth of human neuroblastoma xenografts in vivo, alone and synergistically with all-trans retinoic acid
    • COI: 1:CAS:528:DC%2BD3MXjsFCgtLg%3D, PID: 11325825
    • D.C. Coffey, M.C. Kutko, R.D. Glick, L.M. Butler, G. Heller, R.A. Rifkind, P.A. Marks, V.M. Richon, M.P. La Quaglia, The histone deacetylase inhibitor, CBHA, inhibits growth of human neuroblastoma xenografts in vivo, alone and synergistically with all-trans retinoic acid. Cancer Res. 61, 3591–3594 (2001)
    • (2001) Cancer Res. , vol.61 , pp. 3591-3594
    • Coffey, D.C.1    Kutko, M.C.2    Glick, R.D.3    Butler, L.M.4    Heller, G.5    Rifkind, R.A.6    Marks, P.A.7    Richon, V.M.8    La Quaglia, M.P.9
  • 18
    • 67650090545 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: potential in cancer therapy
    • COI: 1:CAS:528:DC%2BD1MXosFOiurg%3D, PID: 19459166
    • P.A. Marks, W.S. Xu, Histone deacetylase inhibitors: potential in cancer therapy. J. Cell. Biochem. 107, 600–608 (2009)
    • (2009) J. Cell. Biochem. , vol.107 , pp. 600-608
    • Marks, P.A.1    Xu, W.S.2
  • 20
    • 77953170728 scopus 로고    scopus 로고
    • Inhibition of histone acetylase in cancer cells slows down replication forks, activates dormant origins and induces DNA damage
    • COI: 1:CAS:528:DC%2BC3cXmslWgt7w%3D, PID: 20460513
    • C. Conti, E. Leo, G.S. Elchler, O. Sordet, M.M. Martin, A. Fan, M.I. Aladjem, Y. Pommier, Inhibition of histone acetylase in cancer cells slows down replication forks, activates dormant origins and induces DNA damage. Cancer Res. 70, 4470–4480 (2010)
    • (2010) Cancer Res. , vol.70 , pp. 4470-4480
    • Conti, C.1    Leo, E.2    Elchler, G.S.3    Sordet, O.4    Martin, M.M.5    Fan, A.6    Aladjem, M.I.7    Pommier, Y.8
  • 22
    • 84878251843 scopus 로고    scopus 로고
    • Neuroblastoma: developmental biology, cancer genomics and immunotherapy
    • COI: 1:CAS:528:DC%2BC3sXotFSlt7c%3D, PID: 23702928
    • N.K.V. Cheung, M.A. Dyer, Neuroblastoma: developmental biology, cancer genomics and immunotherapy. Nat. Rev. Cancer 13, 397–411 (2013)
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 397-411
    • Cheung, N.K.V.1    Dyer, M.A.2
  • 23
    • 0024468519 scopus 로고
    • Suppression of MYC by high expression of NMYC in human neuroblastoma cells
    • COI: 1:CAS:528:DyaL1MXmtFSjsr8%3D, PID: 2810395
    • S. Breit, M. Schwab, Suppression of MYC by high expression of NMYC in human neuroblastoma cells. J. Neurosci. Res. 24, 21–28 (1989)
    • (1989) J. Neurosci. Res. , vol.24 , pp. 21-28
    • Breit, S.1    Schwab, M.2
  • 24
    • 33846849373 scopus 로고    scopus 로고
    • Functional characterization of a new p53 mutant generated by homozygous deletion in a neuroblastoma cell line
    • COI: 1:CAS:528:DC%2BD2sXhs1Sntr0%3D, PID: 17276397
    • Y. Nakamura, O. Toshinori, H. Niizuma, M. Ohira, T. Kamijo, A. Nakagawara, Functional characterization of a new p53 mutant generated by homozygous deletion in a neuroblastoma cell line. Biochem. Biophys. Res. Commun. 354, 892–898 (2007)
    • (2007) Biochem. Biophys. Res. Commun. , vol.354 , pp. 892-898
    • Nakamura, Y.1    Toshinori, O.2    Niizuma, H.3    Ohira, M.4    Kamijo, T.5    Nakagawara, A.6
  • 25
    • 33644552409 scopus 로고    scopus 로고
    • Increased frequency of aberrations in the p53/MDM2/p14/ARF pathway in neuroblastoma cell lines established at relapse
    • COI: 1:CAS:528:DC%2BD28XhsFalsr0%3D, PID: 16489014
    • J. Carr, E. Bell, A.D.J. Pearson, U.R. Kees, H. Beris, J. Lunec, D.A. Tweddle, Increased frequency of aberrations in the p53/MDM2/p14/ARF pathway in neuroblastoma cell lines established at relapse. Cancer Res. 66, 2138–2145 (2006)
    • (2006) Cancer Res. , vol.66 , pp. 2138-2145
    • Carr, J.1    Bell, E.2    Pearson, A.D.J.3    Kees, U.R.4    Beris, H.5    Lunec, J.6    Tweddle, D.A.7
  • 26
    • 0026091450 scopus 로고
    • Immunohistochemical characterization of primitive neuroectodermal tumors and their possible relationship to the stepwise ontogenetic development of the central nervous system. 1.Ontogenetic studies
    • COI: 1:STN:280:DyaK387ltFGrug%3D%3D, PID: 1723830
    • R. Kleinert, Immunohistochemical characterization of primitive neuroectodermal tumors and their possible relationship to the stepwise ontogenetic development of the central nervous system. 1.Ontogenetic studies. Acta Neuropathol. 82, 502–507 (1991)
    • (1991) Acta Neuropathol. , vol.82 , pp. 502-507
    • Kleinert, R.1
  • 27
    • 82655173729 scopus 로고    scopus 로고
    • MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas
    • COI: 1:CAS:528:DC%2BC3MXhs1Wlt73F, PID: 21856782
    • R. Huang, N.K. Cheung, J. Vider, I.Y. Cheung, W.L. Gerald, S.K. Tickoo, E.C. Holland, R.G. Blasberg, MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas. FASEB J. 25, 4138–4149 (2011)
    • (2011) FASEB J. , vol.25 , pp. 4138-4149
    • Huang, R.1    Cheung, N.K.2    Vider, J.3    Cheung, I.Y.4    Gerald, W.L.5    Tickoo, S.K.6    Holland, E.C.7    Blasberg, R.G.8
  • 28
    • 33644814867 scopus 로고    scopus 로고
    • Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action
    • COI: 1:CAS:528:DC%2BD2MXht1GrtrvN, PID: 16297208
    • C. Zhang, V. Richon, X. Ni, R. Talpur, M. Duvic, Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action. J. Invest. Dermatol. 125, 1045–1052 (2005)
    • (2005) J. Invest. Dermatol. , vol.125 , pp. 1045-1052
    • Zhang, C.1    Richon, V.2    Ni, X.3    Talpur, R.4    Duvic, M.5
  • 29
    • 47349097996 scopus 로고    scopus 로고
    • Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells
    • PID: 18549473
    • A. Muhlethaler-Mottet, R. Meier, M. Flahaut, K.B. Bourloud, K. Nardou, J.M. Joseph, N. Gross, Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells. Mol. Cancer (2008). doi:10.1186/1476-4598-7-55
    • (2008) Mol. Cancer
    • Muhlethaler-Mottet, A.1    Meier, R.2    Flahaut, M.3    Bourloud, K.B.4    Nardou, K.5    Joseph, J.M.6    Gross, N.7
  • 30
    • 27744546085 scopus 로고    scopus 로고
    • Caspase 8/10 are not mediating apoptosis in neuroblastoma cells treated with CDK inhibitory drugs
    • COI: 1:CAS:528:DC%2BD2MXht1SqsLnK, PID: 16243312
    • J. Ribas, X. Gomez-Arbones, J. Boix, Caspase 8/10 are not mediating apoptosis in neuroblastoma cells treated with CDK inhibitory drugs. Eur. J. Pharmacol. 524, 49–52 (2005)
    • (2005) Eur. J. Pharmacol. , vol.524 , pp. 49-52
    • Ribas, J.1    Gomez-Arbones, X.2    Boix, J.3
  • 31
    • 0029743372 scopus 로고    scopus 로고
    • Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
    • COI: 1:CAS:528:DyaK28Xlt1yitb4%3D, PID: 8761302
    • W. Lutz, M. Stohr, J. Schurmann, A. Wenzel, A. Lohr, M. Schwab, Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 13, 803–812 (1996)
    • (1996) Oncogene , vol.13 , pp. 803-812
    • Lutz, W.1    Stohr, M.2    Schurmann, J.3    Wenzel, A.4    Lohr, A.5    Schwab, M.6
  • 32
    • 80052927231 scopus 로고    scopus 로고
    • Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy
    • COI: 1:CAS:528:DC%2BC3MXhtFyjtr%2FM, PID: 21491416
    • M.Y. Chen, W.S. Liao, Z. Lu, W.G. Bornmann, V. Hennessey, M.N. Washington, G.L. Rosner, Y. Yu, A.A. Ahmed, R.C. Bast Jr., Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy. Cancer 117, 4424–4438 (2011)
    • (2011) Cancer , vol.117 , pp. 4424-4438
    • Chen, M.Y.1    Liao, W.S.2    Lu, Z.3    Bornmann, W.G.4    Hennessey, V.5    Washington, M.N.6    Rosner, G.L.7    Yu, Y.8    Ahmed, A.A.9    Bast, R.C.10
  • 33
    • 25444433114 scopus 로고    scopus 로고
    • MDM2 as a critical effector of the MYCN oncogene in tumorigenesis
    • COI: 1:CAS:528:DC%2BD28XhslCrtb0%3D, PID: 15917661
    • A. Slack, J.M. Shohet, MDM2 as a critical effector of the MYCN oncogene in tumorigenesis. Cell Cycle 4, 857–860 (2005)
    • (2005) Cell Cycle , vol.4 , pp. 857-860
    • Slack, A.1    Shohet, J.M.2
  • 34
    • 33748145149 scopus 로고    scopus 로고
    • Mechanisms of transcriptional activation by the Myc oncoproteins
    • COI: 1:CAS:528:DC%2BD28XpsVWksb4%3D, PID: 16935524
    • V.H. Cowling, M.D. Cole, Mechanisms of transcriptional activation by the Myc oncoproteins. Semin Cancer Biol 16, 242–252 (2006)
    • (2006) Semin Cancer Biol , vol.16 , pp. 242-252
    • Cowling, V.H.1    Cole, M.D.2
  • 35
    • 24344451246 scopus 로고    scopus 로고
    • Six lysine residues on c-Myc are direct substrates for acetylation by p300
    • COI: 1:CAS:528:DC%2BD2MXpvFehsLY%3D, PID: 16126174
    • K. Zhang, F. Faiola, E. Martinez, Six lysine residues on c-Myc are direct substrates for acetylation by p300. Biochem. Biophys. Res. Commun. 336, 274–280 (2005)
    • (2005) Biochem. Biophys. Res. Commun. , vol.336 , pp. 274-280
    • Zhang, K.1    Faiola, F.2    Martinez, E.3
  • 36
    • 33845919326 scopus 로고    scopus 로고
    • The ins and outs of MYC regulation by posttranslational mechanisms
    • J. Vervoots, J. Lüscher-Firzlaff, B. Lüscher, The ins and outs of MYC regulation by posttranslational mechanisms. J. Biol. Chem. 281, 34725–34729 (2006)
    • (2006) J. Biol. Chem. , vol.281 , pp. 34725-34729
    • Vervoots, J.1    Lüscher-Firzlaff, J.2    Lüscher, B.3
  • 38
    • 84944166847 scopus 로고    scopus 로고
    • MYCN oncogene targets, , Accessed 21 November (2014)
    • MYCN oncogene targets, http://mellfire.ugent.be/public/mycnot/, Accessed 21 November (2014)
  • 39
    • 0043092201 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma
    • COI: 1:CAS:528:DC%2BD3sXmtFers7s%3D, PID: 12907629
    • M. Alaminos, J. Mora, N.K.V. Cheung, A. Smith, J. Qin, L. Chen, W.L. Gerald, Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma. Cancer Res. 63, 4538–4546 (2003)
    • (2003) Cancer Res. , vol.63 , pp. 4538-4546
    • Alaminos, M.1    Mora, J.2    Cheung, N.K.V.3    Smith, A.4    Qin, J.5    Chen, L.6    Gerald, W.L.7
  • 41
    • 70249085177 scopus 로고    scopus 로고
    • N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53
    • COI: 1:CAS:528:DC%2BD1MXhtFGqsLzK, PID: 19540207
    • R. Janardhanan, N.L. Banik, S.K. Ray, N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53. Biochem. Pharmacol. 78, 1105–1114 (2009)
    • (2009) Biochem. Pharmacol. , vol.78 , pp. 1105-1114
    • Janardhanan, R.1    Banik, N.L.2    Ray, S.K.3
  • 42
    • 0033580238 scopus 로고    scopus 로고
    • MycN sensitizes neuroblastoma cells for drug-induced apoptosis
    • COI: 1:CAS:528:DyaK1MXhs1ygtb0%3D, PID: 10050884
    • S. Fulda, W. Lutz, M. Schwab, K.M. Debatin, MycN sensitizes neuroblastoma cells for drug-induced apoptosis. Oncogene 18, 1479–1485 (1999)
    • (1999) Oncogene , vol.18 , pp. 1479-1485
    • Fulda, S.1    Lutz, W.2    Schwab, M.3    Debatin, K.M.4
  • 43
    • 57149096666 scopus 로고    scopus 로고
    • N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor
    • COI: 1:CAS:528:DC%2BD1cXhsVegtbrE, PID: 19047142
    • R. Cotterman, V.X. Jin, S.R. Krig, J.M. Lemen, A. Wey, P.J. Farnham, P.S. Knoepfler, N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. Cancer Res. 68, 9654–9662 (2008)
    • (2008) Cancer Res. , vol.68 , pp. 9654-9662
    • Cotterman, R.1    Jin, V.X.2    Krig, S.R.3    Lemen, J.M.4    Wey, A.5    Farnham, P.J.6    Knoepfler, P.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.