-
1
-
-
79959962745
-
Hormonal regulation of hepatic glucose production in health and disease
-
Lin HV, Accili D. Hormonal regulation of hepatic glucose production in health and disease. Cell Metab. 2011;14:9-19.
-
(2011)
Cell Metab
, vol.14
, pp. 9-19
-
-
Lin, H.V.1
Accili, D.2
-
2
-
-
45749158925
-
Central insulin action regulates peripheral glucose and fat metabolism in mice
-
Koch L, Wunderlich FT, Seibler J, et al. Central insulin action regulates peripheral glucose and fat metabolism in mice. J Clin Invest. 2008;118:2132-2147.
-
(2008)
J Clin Invest
, vol.118
, pp. 2132-2147
-
-
Koch, L.1
Wunderlich, F.T.2
Seibler, J.3
-
3
-
-
34249651956
-
Insulin action in AgRPexpressing neurons is required for suppression of hepatic glucose production
-
Könner AC, Janoschek R, Plum L, et al. Insulin action in AgRPexpressing neurons is required for suppression of hepatic glucose production. Cell Metab. 2007;5:438-449.
-
(2007)
Cell Metab
, vol.5
, pp. 438-449
-
-
Könner, A.C.1
Janoschek, R.2
Plum, L.3
-
4
-
-
84867033830
-
Insulin activates Erk1/2 signaling in the dorsal vagal complex to inhibit glucose production
-
Filippi BM, Yang CS, Tang C, Lam TK. Insulin activates Erk1/2 signaling in the dorsal vagal complex to inhibit glucose production. Cell Metab. 2012;16:500-510.
-
(2012)
Cell Metab
, vol.16
, pp. 500-510
-
-
Filippi, B.M.1
Yang, C.S.2
Tang, C.3
Lam, T.K.4
-
5
-
-
0036913187
-
Hypothalamic insulin signaling is required for inhibition of glucose production
-
Obici S, Zhang BB, Karkanias G, Rossetti L. Hypothalamic insulin signaling is required for inhibition of glucose production. Nat Med. 2002;8:1376-1382.
-
(2002)
Nat Med
, vol.8
, pp. 1376-1382
-
-
Obici, S.1
Zhang, B.B.2
Karkanias, G.3
Rossetti, L.4
-
6
-
-
17844379717
-
Hypothalamic K(ATP) channels control hepatic glucose production
-
Pocai A, Lam TK, Gutierrez-Juarez R, et al. Hypothalamic K(ATP) channels control hepatic glucose production. Nature. 2005;434: 1026-1031.
-
(2005)
Nature
, vol.434
, pp. 1026-1031
-
-
Pocai, A.1
Lam, T.K.2
Gutierrez-Juarez, R.3
-
7
-
-
33645579324
-
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production
-
Inoue H, Ogawa W, Asakawa A, et al. Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab. 2006;3:267-275.
-
(2006)
Cell Metab
, vol.3
, pp. 267-275
-
-
Inoue, H.1
Ogawa, W.2
Asakawa, A.3
-
8
-
-
79551506567
-
Brain insulin controls adipose tissue lipolysis and lipogenesis
-
Scherer T, O'Hare J, Diggs-Andrews K, et al. Brain insulin controls adipose tissue lipolysis and lipogenesis. Cell Metab. 2011;13:183-194.
-
(2011)
Cell Metab
, vol.13
, pp. 183-194
-
-
Scherer, T.1
O'hare, J.2
Diggs-Andrews, K.3
-
9
-
-
32444434587
-
Insulin's direct effects on the liver dominate the control of hepatic glucose production
-
Edgerton DS, Lautz M, Scott M, et al. Insulin's direct effects on the liver dominate the control of hepatic glucose production. J Clin Invest. 2006;116:521-527.
-
(2006)
J Clin Invest
, vol.116
, pp. 521-527
-
-
Edgerton, D.S.1
Lautz, M.2
Scott, M.3
-
10
-
-
80052345224
-
Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs
-
Ramnanan CJ, Saraswathi V, Smith MS, et al. Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs. J Clin Invest. 2011;121: 3713-3723.
-
(2011)
J Clin Invest
, vol.121
, pp. 3713-3723
-
-
Ramnanan, C.J.1
Saraswathi, V.2
Smith, M.S.3
-
11
-
-
84055184949
-
Activation of K(ATP) channels suppresses glucose production in humans
-
Kishore P, Boucai L, Zhang K, et al. Activation of K(ATP) channels suppresses glucose production in humans. J Clin Invest. 2011;121: 4916-4920.
-
(2011)
J Clin Invest
, vol.121
, pp. 4916-4920
-
-
Kishore, P.1
Boucai, L.2
Zhang, K.3
-
12
-
-
85047698627
-
Sniffing neuropeptides: A transnasal approach to the human brain
-
Born J, Lange T, Kern W, McGregor GP, Bickel U, Fehm HL. Sniffing neuropeptides: a transnasal approach to the human brain. Nat Neurosci. 2002;5:514-516.
-
(2002)
Nat Neurosci
, vol.5
, pp. 514-516
-
-
Born, J.1
Lange, T.2
Kern, W.3
McGregor, G.P.4
Bickel, U.5
Fehm, H.L.6
-
13
-
-
84859526987
-
Postprandial administration of intranasal insulin intensifies satiety and reduces intake of palatable snacks in women
-
Hallschmid M, Higgs S, Thienel M, Ott V, Lehnert H. Postprandial administration of intranasal insulin intensifies satiety and reduces intake of palatable snacks in women. Diabetes. 2012;61:782-789.
-
(2012)
Diabetes
, vol.61
, pp. 782-789
-
-
Hallschmid, M.1
Higgs, S.2
Thienel, M.3
Ott, V.4
Lehnert, H.5
-
14
-
-
84865434170
-
Nasal insulin changes peripheral insulin sensitivity simultaneously with altered activity in homeostatic and reward-related human brain regions
-
Heni M, Kullmann S, Ketterer C, et al. Nasal insulin changes peripheral insulin sensitivity simultaneously with altered activity in homeostatic and reward-related human brain regions. Diabetologia. 2012;55:1773-1782.
-
(2012)
Diabetologia
, vol.55
, pp. 1773-1782
-
-
Heni, M.1
Kullmann, S.2
Ketterer, C.3
-
15
-
-
76149103529
-
Insulin modulates foodrelated activity in the central nervous system
-
Guthoff M, Grichisch Y, Canova C, et al. Insulin modulates foodrelated activity in the central nervous system. J Clin Endocrinol Metab. 2010;95:748-755.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 748-755
-
-
Guthoff, M.1
Grichisch, Y.2
Canova, C.3
-
16
-
-
84928209333
-
Intranasal insulin suppresses endogenous glucose production in humans compared with placebo in the presence of similar venous insulin concentrations
-
Dash S, Xiao C, Morgantini C, Koulajian K, Lewis GF. Intranasal insulin suppresses endogenous glucose production in humans compared with placebo in the presence of similar venous insulin concentrations. Diabetes. 2015;64:766-774.
-
(2015)
Diabetes
, vol.64
, pp. 766-774
-
-
Dash, S.1
Xiao, C.2
Morgantini, C.3
Koulajian, K.4
Lewis, G.F.5
-
17
-
-
84911916822
-
Central insulin administration improves whole-body insulin sensitivity via hypothalamus and parasympathetic outputs in men
-
Heni M, Wagner R, Kullmann S, et al. Central insulin administration improves whole-body insulin sensitivity via hypothalamus and parasympathetic outputs in men. Diabetes. 2014;63: 4083-4088.
-
(2014)
Diabetes
, vol.63
, pp. 4083-4088
-
-
Heni, M.1
Wagner, R.2
Kullmann, S.3
-
18
-
-
84928211042
-
Central nervous insulin administration does not potentiate the acute glucoregulatory impact of concurrent mild hyperinsulinemia
-
Ott V, Lehnert H, Staub J, Wönne K, Born J, Hallschmid M. Central nervous insulin administration does not potentiate the acute glucoregulatory impact of concurrent mild hyperinsulinemia. Diabetes. 2015;64:760-765.
-
(2015)
Diabetes
, vol.64
, pp. 760-765
-
-
Ott, V.1
Lehnert, H.2
Staub, J.3
Wönne, K.4
Born, J.5
Hallschmid, M.6
-
19
-
-
84872044062
-
Interaction between the central and peripheral effects of insulin in controlling hepatic glucose metabolism in the conscious dog
-
Ramnanan CJ, Kraft G, Smith MS, et al. Interaction between the central and peripheral effects of insulin in controlling hepatic glucose metabolism in the conscious dog. Diabetes. 2013;62:74-84.
-
(2013)
Diabetes
, vol.62
, pp. 74-84
-
-
Ramnanan, C.J.1
Kraft, G.2
Smith, M.S.3
-
20
-
-
0025063027
-
Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid
-
Schwartz MW, Sipols A, Kahn SE, et al. Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. Am J Physiol. 1990;259:E378-E383.
-
(1990)
Am J Physiol
, vol.259
, pp. E378-E383
-
-
Schwartz, M.W.1
Sipols, A.2
Kahn, S.E.3
-
21
-
-
0023153353
-
Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man
-
Wallum BJ, Taborsky GJ Jr, Porte D Jr, et al. Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man. J Clin Endocrinol Metab. 1987;64:190-194.
-
(1987)
J Clin Endocrinol Metab
, vol.64
, pp. 190-194
-
-
Wallum, B.J.1
Taborsky, G.J.2
Porte, D.3
-
22
-
-
84931289812
-
Effects of intranasal insulin on hepatic fat accumulation and energy metabolism in humans
-
Gancheva S, Koliaki C, Bierwagen A, et al. Effects of intranasal insulin on hepatic fat accumulation and energy metabolism in humans. Diabetes. 2015;64:1966-1975.
-
(2015)
Diabetes
, vol.64
, pp. 1966-1975
-
-
Gancheva, S.1
Koliaki, C.2
Bierwagen, A.3
-
23
-
-
0034891405
-
Transport of nanoparticles across the rat nasal mucosa
-
Brooking J, Davis SS, Illum L. Transport of nanoparticles across the rat nasal mucosa. J Drug Target. 2001;9:267-279.
-
(2001)
J Drug Target
, vol.9
, pp. 267-279
-
-
Brooking, J.1
Davis, S.S.2
Illum, L.3
-
24
-
-
0037052544
-
Ablation of insulin-producing neurons in flies: Growth and diabetic phenotypes
-
Rulifson EJ, Kim SK, Nusse R. Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science. 2002;296: 1118-1120.
-
(2002)
Science
, vol.296
, pp. 1118-1120
-
-
Rulifson, E.J.1
Kim, S.K.2
Nusse, R.3
-
25
-
-
84870537777
-
Hyperinsulinemia drives diet-induced obesity independently of brain insulin production
-
Mehran AE, Templeman NM, Brigidi GS, et al. Hyperinsulinemia drives diet-induced obesity independently of brain insulin production. Cell Metab. 2012;16:723-737.
-
(2012)
Cell Metab
, vol.16
, pp. 723-737
-
-
Mehran, A.E.1
Templeman, N.M.2
Brigidi, G.S.3
-
26
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes
-
Steen E, Terry BM, Rivera EJ, et al. Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimers Dis. 2005;7:63-80.
-
(2005)
J Alzheimers Dis
, vol.7
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
-
27
-
-
0018621289
-
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons
-
Woods SC, Lotter EC, McKay LD, Porte D Jr. Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature. 1979;282:503-505.
-
(1979)
Nature
, vol.282
, pp. 503-505
-
-
Woods, S.C.1
Lotter, E.C.2
McKay, L.D.3
Porte, D.4
-
28
-
-
7044241101
-
Intranasal insulin reduces body fat in men but not in women
-
Hallschmid M, Benedict C, Schultes B, Fehm HL, Born J, Kern W. Intranasal insulin reduces body fat in men but not in women. Diabetes. 2004;53:3024-3029.
-
(2004)
Diabetes
, vol.53
, pp. 3024-3029
-
-
Hallschmid, M.1
Benedict, C.2
Schultes, B.3
Fehm, H.L.4
Born, J.5
Kern, W.6
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