miR-125a-5p inhibits cell proliferation and induces apoptosis in colon cancer via targeting BCL2, BCL2L12 and MCL1

Biomedicine and Pharmacotherapy

Volumn 75, Issue , 2015, Pages 129-136

  Tong, Zhiguo ^a   Liu, Nan ^b   Lin, Luoqiang ^a   Guo, Xinggang ^a   Yang, Dongdong ^a   Zhang, Qifan ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

BCL2; BCL2L12; Colon cancer; Mcl 1; miR 125a 5p

Indexed keywords

ANTINEOPLASTIC AGENT; BCL 2 LIKE 12 PROTEIN; CASPASE 3; LUCIFERASE; MESSENGER RNA; MICRORNA; MICRORNA 125A 5P; PROTEIN; PROTEIN BCL 2; PROTEIN MCL 1; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; BCL2 PROTEIN, HUMAN; BCL2L12 PROTEIN, HUMAN; MCL1 PROTEIN, HUMAN; MIRN125 MICRORNA, HUMAN; MUSCLE PROTEIN;

3' UNTRANSLATED REGION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING SITE; CANCER INHIBITION; CANCER REGRESSION; CELL PROLIFERATION; CELL STIMULATION; COLON CANCER; COLON CARCINOGENESIS; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME REPRESSION; G1 PHASE CELL CYCLE CHECKPOINT; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; CACO-2 CELL LINE; COLON TUMOR; GENE EXPRESSION REGULATION; GENETICS; HCT 116 CELL LINE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TIME FACTOR;

3' UNTRANSLATED REGIONS; APOPTOSIS; BINDING SITES; CACO-2 CELLS; CELL PROLIFERATION; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; MICRORNAS; MUSCLE PROTEINS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84944151703     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2015.07.036     Document Type: Article

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