Truncation of the C-terminal region of Toscana Virus NSs protein is critical for interferon-β antagonism and protein stability

Virology

Volumn 486, Issue , 2015, Pages 255-262

  Gori Savellini, Gianni ^a   Gandolfo, Claudia ^a   Cusi, Maria Grazia ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

C terminal deleted protein; Non structural protein; RIG I; Toscana Virus

Indexed keywords

AMINO ACID; BETA INTERFERON; NONSTRUCTURAL PROTEIN DELTA 1C; NONSTRUCTURAL PROTEIN DELTA 2C; RETINOIC ACID INDUCIBLE PROTEIN I; TOSCANA VIRUS NONSTRUCTURAL PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE CONSTRUCT; GENE DELETION; GENE MAPPING; GENE SEQUENCE; HUMAN; HUMAN CELL; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; QUANTITATIVE TRAIT LOCUS; SIGNAL TRANSDUCTION; TOSCANA VIRUS; VIRUS REPLICATION; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN MOTIF; SANDFLY FEVER; SANDFLY FEVER NAPLES VIRUS; VIROLOGY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; DEAD-BOX RNA HELICASES; HUMANS; INTERFERON-BETA; MOLECULAR SEQUENCE DATA; PHLEBOTOMUS FEVER; PROTEIN STABILITY; SANDFLY FEVER NAPLES VIRUS; SEQUENCE DELETION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84944053617     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2015.09.021     Document Type: Article

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