Transcranial direct current stimulation in treatment-resistant obsessive-compulsive disorder: An open-label pilot study

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 65, Issue , 2016, Pages 153-157

  Bation, Remy ^a   Poulet, Emmanuel ^a,b   Haesebaert, Frederic ^a   Saoud, Mohamed ^a,c   Brunelin, Jerome ^a  

^a UNIVERSITÉ LYON 1   (France)

^b HOSPICES CIVILS DE LYON   (France)

^c HÔPITAL NEUROLOGIQUE   (France)

Author keywords

Cerebellum; Obsessive compulsive disorder; OCD; OFC; Orbitofrontal cortex; TDCS; Transcranial direct current stimulation

Indexed keywords

ARIPIPRAZOLE; CLOMIPRAMINE; FLUOXETINE; OXAZEPAM; PAROXETINE; PRAZEPAM; RISPERIDONE; SERTRALINE; VALPROIC ACID;

ADULT; ARTICLE; CEREBELLUM; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DEPRESSION; ERYTHEMA; FEMALE; FOLLOW UP; HUMAN; MALE; MIDDLE AGED; OBSESSIVE COMPULSIVE DISORDER; ORBITAL CORTEX; PHYSICAL TOLERANCE; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; RIGHT CEREBELLUM; SKIN DEFECT; TRANSCRANIAL DIRECT CURRENT STIMULATION; TREATMENT RESPONSE; DRUG RESISTANCE; OBSESSIVE-COMPULSIVE DISORDER; PATHOPHYSIOLOGY; PROCEDURES; PSYCHOLOGICAL RATING SCALE; TREATMENT OUTCOME;

ADULT; CEREBELLUM; DRUG RESISTANCE; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; OBSESSIVE-COMPULSIVE DISORDER; PILOT PROJECTS; PSYCHIATRIC STATUS RATING SCALES; TRANSCRANIAL DIRECT CURRENT STIMULATION; TREATMENT OUTCOME;

EID: 84943646383     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2015.10.001     Document Type: Article

References (46)

1. Anticevic A., Hu S., Zhang S., Savic A., Billingslea E., Wasylink S., Repovs G., Cole M.W., Bednarski S., Krystal J.H., Bloch M.H., Li C.S., Pittenger C. Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder. Biol. Psychiatry 2014, 75(8):595-605.
2. Berlim M.T., Neufel N.H., Van den Eynde F. Repetitive transcranial magnetic stimulation (rTMS) for obsessive-compulsive disorder (OCD): an exploratory meta-analysis of randomized and sham-controlled trials. J. Psychiatr. Res. 2013, 47:999-1006.
3. Boehringer A., Macher K., Dukart J., Villringer A., Pleger B. Cerebellar transcranial direct current stimulation modulates verbal working memory. Brain Stimul. 2013, 6(4):649-653.
4. Bostan A.C., Dum R.P., Strick P.L. Cerebellar networks with the cerebral cortex and basal ganglia. Trends Cogn. Sci. 2013, 17(5):241-254. (May).
5. Brunelin J., Mondino M., Gassab L., Haesebaert F., Gaha L., Suaud-Chagny M.F., Saoud M., Mechri A., Poulet E. Examining transcranial direct-current stimulation (tDCS) as a treatment for hallucinations in schizophrenia. Am. J. Psychiatry 2012, 169(7):719-724.
6. Brunoni A.R., Amadera J., Berbel B., Volz M.S., Rizzerio B.G., Fregni F. A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation. Int. J. Neuropsychopharmacol. 2011, 14:1133-1145.
7. Brunoni A.R., Valiengo L., Baccaro A., Zanão T.A., de Oliveira J.F., Goulart A., Boggio P.S., Lotufo P.A., Benseñor I.M., Fregni F. The sertraline vs. electrical current therapy for treating depression clinical study: results from a factorial, randomized, controlled trial. JAMA Psychiatry 2013, 70(4):383-391.
8. Callu D., Puget S., Faure A., Guegan M., El Massioui N. Habit learning dissociation in rats with lesions to the vermis and the interpositus of the cerebellum. Neurobiol. Dis. 2007, 27(2):228-237. (Aug).
9. De Smet H.J., Paquier P., Verhoeven J., Mariën P. The cerebellum: its role in language and related cognitive and affective functions. Brain Lang. 2013, 127(3):334-342. (Dec).
10. De Wit S.J., Alonso P., Schweren L., Mataix-Cols D., Lochner C., Menchón J.M., et al. Multicenter voxel-based morphometry mega-analysis of structural brain scans in obsessive-compulsive disorder. Am. J. Psychiatry. 2014, 171(3):340-349.
11. Demirtas-Tatlidede A., Freitas C., Cromer J.R., Safar L., Ongur D., Stone W.S., Seidman L.J., Schmahmann J.D., Pascual-Leone A. Safety and proof of principle study of cerebellar vermal theta burst stimulation in refractory schizophrenia. Schizophr. Res. 2010, 124(1-3):91-100.
12. D'Urso G., Brunoni A.R., Anastasia A., Micillo M., de Bartolomeis A., Mantovani A. Polarity-dependent effects of transcranial direct current stimulation in obsessive-compulsive disorder. Neurocase 2015, 14:1-5. (May, Epub ahead of print).
13. Eng G.K., Sim K., Chen S.H. Meta-analytic investigations of structural grey matter, executive domain-related functional activations, and white matter diffusivity in obsessive compulsive disorder: an integrative review. Neurosci. Biobehav. Rev. 2015, 52:233-257.
14. Foa E.B., Liebowitz M.R., Kozak M.J., Davies S., Campeas R., Franklin M.E., Huppert J.D., Kjernisted K., Rowan V., Schmidt A.B., Simpson H.B., Tu X. Randomized, placebo-controlled trial of exposure and ritual prevention, clomipramine, and their combination in the treatment of obsessive-compulsive disorder. Am. J. Psychiatry 2005, 162:151-161.
15. Gillan C.M., Robbins T.W. Goal-directed learning and obsessive-compulsive disorder. Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci. 2014, 369(1655). (Nov 5).
16. Goodman W.K., Price L.H., Rasmussen S.A., et al. The Yale-Brown obsessive compulsive scale, II: validity. Arch. Gen. Psychiatry 1989, 46(11):1012-1016.
17. Grimaldi G., Argyropoulos G.P., Bastian A., Cortes M., Davis N.J., Edwards D.J., Ferrucci R., Fregni F., Galea J.M., Hamada M., Manto M., Miall R.C., Morales-Quezada L., Pope P.A., Priori A., Rothwell J., Tomlinson S.P., Celnik P. Cerebellar Transcranial Direct Current Stimulation (ctDCS): a novel approach to understanding cerebellar function in health and disease. Neuroscientist 2014, (Nov 18. pii: 1073858414559409).
18. Ho K.A., Bai S., Martin D., Alonzo A., Dokos S., Puras P., Loo C.K. A pilot study of alternative transcranial direct current stimulation electrode montages for the treatment of major depression. J. Affect. Disord. 2014, 167:251-258.
19. Hou J., Wu W., Lin Y., Wang J., Zhou D., Guo J., Gu S., He M., Ahmed S., Hu J., Qu W., Li H. Localization of cerebral functional deficits in patients with obsessive-compulsive disorder: a resting-state fMRI study. J. Affect. Disord. 2012, 138(3):313-321.
20. Jaafari N., Rachid F., Rotge J.Y., Polosan M., El-Hage W., Belin D., Vibert N., Pelissolo A. Safety and efficacy of repetitive transcranial magnetic stimulation in the treatment of obsessive-compulsive disorder: a review. World World J. Biol. Psychiatry 2012, 13(3):164-177.
21. Keeser D., Meindl T., Bor J., Palm U., Pogarell O., Mulert C., Brunelin J., Möller H.J., Reiser M., Padberg F. Prefrontal transcranial direct current stimulation changes connectivity of resting-state networks during fMRI. J. Neurosci. 2011, 31(43):15284-15293.
22. Koziol L.F., Budding D., Andreasen N., D'Arrigo S., Bulgheroni S., Imamizu H., et al. Consensus paper: the cerebellum's role in movement and cognition. Cerebellum 2014, 13(1):151-177. (Feb).
23. Lefaucheur J.P., André-Obadia N., Antal A., Ayache S.S., Baeken C., Benninger D.H., Cantello R.M., Cincotta M., de Carvalho M., De Ridder D., Devanne H., Di Lazzaro V., Filipović S.R., Hummel F.C., Jääskeläinen S.K., Kimiskidis V.K., Koch G., Langguth B., Nyffeler T., Oliviero A., Padberg F., Poulet E., Rossi S., Rossini P.M., Rothwell J.C., Schönfeldt-Lecuona C., Siebner H.R., Slotema C.W., Stagg C.J., Valls-Sole J., Ziemann U., Paulus W., Garcia-Larrea L. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). Clin. Neurophysiol. 2014, 125(11):2150-2206.
24. Liljeholm M., Dunne S., O'Doherty J.P. Differentiating neural systems mediating the acquisition vs. expression of goal-directed and habitual behavioral control. Eur. J. Neurosci. 2015, 41(10):1358-1371. (May).
25. Maia T.V., Cooney R.E., Peterson B.S. The neural bases of obsessive-compulsive disorder in children and adults. Dev. Psychopathol. 2008, 20(4):1251-1283.
26. Mantovani A., Simpson H.B., Fallon B.A., Rossi S., Lisanby S.H. Randomized sham-controlled trial of repetitive transcranial magnetic stimulation in treatment-resistant obsessive-compulsive disorder. Int. J. Neuropsychopharmacol. 2010, 13:217-227.
27. Modirrousta M., Shams E., Katz C., Mansouri B., Moussavi Z., Sareen J., Enns M. The efficacy of deep repetitive transcranial magnetic stimulation over the medial prefrontal cortex in obsessive compulsive disorder: results from an open-label study. Depress. Anxiety 2015, 32(6):445-450.
28. Mondino M., Bennabi D., Poulet E., Galvao F., Brunelin J., Haffen E. Can transcranial direct current stimulation (tDCS) alleviate symptoms and improve cognition in psychiatric disorders?. World J. Biol. Psychiatry 2014, 15(4):261-275.
29. Mondino M., Haesebaert F., Poulet E., Saoud M., Brunelin J. Efficacy of cathodal transcranial direct current stimulation over the left orbitofrontal cortex in a patient with treatment-resistant obsessive-compulsive disorder. J ECT 2015, 3. (Feb).
30. Montgomery S.A., Asberg M. A new depression scale designed to be sensitive to change. Br. J. Psychiatry 1979, 134:383e9.
31. Nabeyama M., Nakagawa A., Yoshiura T., Nakao T., Nakatani E., Togao O., Yoshizato C., Yoshioka K., Tomita M., Kanba S. Functional MRI study of brain activation alterations in patients with obsessive-compulsive disorder after symptom improvement. Psychiatry Res. 2008, 163(3):236-247.
32. Nakao T., Nakagawa A., Yoshiura T., Nakatani E., Nabeyama M., Yoshizato C., et al. Brain activation of patients with obsessive-compulsive disorder during neuropsychological and symptom provocation tasks before and after symptom improvement: a functional magnetic resonance imaging study. Biol. Psychiatry 2005, 57(8):901-910. (Apr 15).
33. Nakao T., Okada K., Kanba S. Neurobiological model of obsessive-compulsive disorder: evidence from recent neuropsychological and neuroimaging findings. Psychiatry Clin. Neurosci. 2014, 68(8):587-605. (Aug).
34. Narayanaswamy J.C., Jose D., Chhabra H., Agarwal S.M., Shrinivasa B., Hegde A., Bose A., Kalmady S.V., Venkatasubramanian G., Reddy Y.C. Successful application of add-on transcranial direct current stimulation (tDCS) for treatment of SSRI resistant OCD. Brain Stimul. 2015, 8(3):655-657.
35. Nitsche M.A., Liebetanz D., Antal A., Lang N., Tergau F., Paulus W. Modulation of cortical excitability by weak direct current stimulation-technical, safety and functional aspects. Suppl. Clin. Neurophysiol. 2003, 56:255-276.
36. Pallanti S., Quercioli L. Treatment-refractory obsessive-compulsive disorder: methodological issues, operational definitions and therapeutic lines. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2006, 30(3):400-412.
37. Pallanti S., Hollander E., Goodman W.K. A qualitative analysis of non response: management of treatment-refractory obsessive-compulsive disorder. J. Clin. Psychiatry 2004, 65(14):6-10.
38. Pope P.A., Miall R.C. Task-specific facilitation of cognition by cathodal transcranial direct current stimulation of the cerebellum. Brain Stimul. 2012, 5(2):84-94.
39. Ruffini C., Locatelli M., Lucca A., Benedetti F., Insacco C., Smeraldi E. Augmentation effect of repetitive transcranial magnetic stimulation over the orbitofrontal cortex in drug resistant obsessive-compulsive disorder patients: a controlled investigation. Prim. Care Companion J. Clin. Psychiatry 2009, 11:226-230.
40. Sanematsu H., Nakao T., Yoshiura T., Nabeyama M., Togao O., Tomita M., Masuda Y., Nakatani E., Nakagawa A., Kanba S. Predictors of treatment response to fluvoxamine in obsessive-compulsive disorder: an fMRI study. J. Psychiatr. Res. 2010, 44(4):193-200.
41. Senço N.M., Huang Y., D'Urso G., Parra L.C., Bikson M., Mantovani A., Shavitt R.G., Hoexter M.Q., Miguel E.C., Brunoni A.R. Transcranial direct current stimulation in obsessive-compulsive disorder: emerging clinical evidence and considerations for optimal montage of electrodes. Expert Rev. Med. Devices 2015, 12(4):381-391.
42. Tolin D.F., Abramowitz J.S., Diefenbach G.J. Defining response in clinical trials for obsessive-compulsive disorder: a signal detection analysis of the Yale-Brown obsessive compulsive scale. J. Clin. Psychiatry 2005, 66:1549-1557.
43. Volpato C., Piccione F., Cavinato M., Duzzi D., Schiff S., Foscolo L., Venneri A. Modulation of affective symptoms and resting state activity by brain stimulation in a treatment-resistant case of obsessive-compulsive disorder. Neurocase 2013, 19(4):360-370.
44. Wen S.-L., Cheng M.-H., Cheng M.-F., Yue J.-H., Wang H. Pharmacotherapy response and regional cerebral blood flow characteristics in patients with obsessive-compulsive disorder. Behav. Brain Funct. 2013, 9:31.
45. Zhang T., Wang J., Yang Y., Wu Q., Li B., Chen L., et al. Abnormal small-world architecture of top-down control networks in obsessive-compulsive disorder. J. Psychiatry Neurosci. 2011, 36(1):23-31. (Jan).
46. Zuo C., Ma Y., Sun B., Peng S., Zhang H., Eidelberg D., Guan Y. Metabolic imaging of bilateral anterior capsulotomy in refractory obsessive compulsive disorder: an FDG PET study. J. Cereb. Blood Flow Metab. 2013, 33(6):880-887.