Engineering vascularized soft tissue flaps in an animal model using human adipose-derived stem cells and VEGF+PLGA/PEG microspheres on a collagen-chitosan scaffold with a flow-through vascular pedicle

Biomaterials

Volumn 73, Issue , 2015, Pages 198-213

  Zhang, Qixu ^a   Hubenak, Justin ^a   Iyyanki, Tejaswi ^a   Alred, Erik ^a   Turza, Kristin C ^a   Davis, Greg ^a   Chang, Edward I ^a   Branch Brooks, Cynthia D ^a   Beahm, Elisabeth K ^a   Butler, Charles E ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Adipose derived stem cell; Collagen chitosan scaffold; PLGA PEG microsphere; Soft tissue flap engineering; Vascular endothelial growth factor; Vascularization

Indexed keywords

CELL ENGINEERING; CELLS; CHITIN; CHITOSAN; COLLAGEN; CYTOLOGY; ENDOTHELIAL CELLS; INTEGRATION TESTING; MICROSPHERES; SCAFFOLDS (BIOLOGY); STEM CELLS; TISSUE;

ADIPOSE DERIVED STEM CELLS; CHITOSAN SCAFFOLD; SOFT TISSUE; VASCULAR ENDOTHELIAL GROWTH FACTOR; VASCULARIZATION;

TISSUE ENGINEERING;

CHITOSAN; COLLAGEN; MACROGOL; MICROSPHERE; POLYGLACTIN; VASCULOTROPIN; CONDITIONED MEDIUM; GREEN FLUORESCENT PROTEIN; LACTIC ACID; MACROGOL DERIVATIVE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; SILICONE DERIVATIVE; VASCULOTROPIN A;

ADIPOGENESIS; ADIPOSE DERIVED STEM CELL; ADIPOSE TISSUE; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOTRANSPLANTATION; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE ENGINEERING; TISSUE FLAP; VASCULAR PEDICLE; ADIPOCYTE; ANIMAL; AORTA; CELL PROLIFERATION; CHEMISTRY; CONDITIONED MEDIUM; CYTOLOGY; FLUORESCENCE MICROSCOPY; HUMAN; IMMUNOHISTOCHEMISTRY; MACROPHAGE; NUDE RAT; PATHOLOGY; PROCEDURES; SCANNING ELECTRON MICROSCOPY; STEM CELL; SURGICAL FLAPS; TISSUE SCAFFOLD;

ADIPOCYTES; ANIMALS; AORTA; CELL PROLIFERATION; CELL SURVIVAL; CHITOSAN; COLLAGEN; CULTURE MEDIA, CONDITIONED; FEMALE; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; LACTIC ACID; MACROPHAGES; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; MICROSPHERES; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; RATS; RATS, NUDE; SILICONES; STEM CELLS; SURGICAL FLAPS; TISSUE ENGINEERING; TISSUE SCAFFOLDS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84943557933     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.09.024     Document Type: Article

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