메뉴 건너뛰기




Volumn 14, Issue 1, 2015, Pages

Effect of metformin monotherapy on cardiovascular diseases and mortality: A retrospective cohort study on Chinese type 2 diabetes mellitus patients

Author keywords

Cardiovascular disease; Diabetes care; Diabetes mellitus; Metformin; Mortality

Indexed keywords

METFORMIN; ANTIDIABETIC AGENT;

EID: 84943528198     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-015-0304-2     Document Type: Article
Times cited : (61)

References (46)
  • 1
    • 84943565877 scopus 로고    scopus 로고
    • The 6th Edition of the IDF Diabetes Atlas
    • Brussels: International Diabetes Federation.
    • International Diabetes Federation. The 6th Edition of the IDF Diabetes Atlas. Brussels: International Diabetes Federation; 2014.
    • (2014)
  • 2
    • 79961060508 scopus 로고    scopus 로고
    • Global Status Report on Noncommunicable Diseases
    • Geneva: World Health Organization
    • World Health Organization. Global Status Report on Noncommunicable Diseases 2010. Geneva: World Health Organization; 2010.
    • (2010)
  • 3
    • 77958172772 scopus 로고    scopus 로고
    • The Effect of Oral Antidiabetic Agents on A1C Levels: a systematic review and meta-analysis
    • Sherifali D, Nerenberg K, Pullenayegum E, Cheng JE, Gerstein HC. The Effect of Oral Antidiabetic Agents on A1C Levels: a systematic review and meta-analysis. Diabetes Care. 2010;33(8):1859-64.
    • (2010) Diabetes Care , vol.33 , Issue.8 , pp. 1859-1864
    • Sherifali, D.1    Nerenberg, K.2    Pullenayegum, E.3    Cheng, J.E.4    Gerstein, H.C.5
  • 4
    • 0347933028 scopus 로고    scopus 로고
    • Metformin hydrochloride in the treatment of type 2 diabetes mellitus: a clinical review with a focus on dual therapy
    • Setter SM, Iltz JL, Thams J, Campbell RK. Metformin hydrochloride in the treatment of type 2 diabetes mellitus: a clinical review with a focus on dual therapy. Clin Ther. 2003;25(12):2991-3026.
    • (2003) Clin Ther , vol.25 , Issue.12 , pp. 2991-3026
    • Setter, S.M.1    Iltz, J.L.2    Thams, J.3    Campbell, R.K.4
  • 5
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34
    • UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34. Lancet. 1998;352(9131):854-65.
    • (1998) Lancet , vol.352 , Issue.9131 , pp. 854-865
  • 6
    • 39749193949 scopus 로고    scopus 로고
    • An audit on diabetes management in Asian patients treated by specialists: the Diabcare-Asia 1998 and 2003 studies
    • Mohamed M. An audit on diabetes management in Asian patients treated by specialists: the Diabcare-Asia 1998 and 2003 studies. Curr Med Res Opin. 2008;24(2):507-14.
    • (2008) Curr Med Res Opin , vol.24 , Issue.2 , pp. 507-514
    • Mohamed, M.1
  • 8
    • 84876380021 scopus 로고    scopus 로고
    • Real-world factors affecting adherence to insulin therapy in patients with Type 1 or Type 2 diabetes mellitus: a systematic review
    • Davies MJ, Gagliardino JJ, Gray LJ, Khunti K, Mohan V, Hughes R. Real-world factors affecting adherence to insulin therapy in patients with Type 1 or Type 2 diabetes mellitus: a systematic review. Diabet Med. 2013;30(5):512-24.
    • (2013) Diabet Med , vol.30 , Issue.5 , pp. 512-524
    • Davies, M.J.1    Gagliardino, J.J.2    Gray, L.J.3    Khunti, K.4    Mohan, V.5    Hughes, R.6
  • 9
    • 3343024281 scopus 로고    scopus 로고
    • Weight Management Through Lifestyle Modification for the Prevention and Management of Type 2 Diabetes: rationale and Strategies: A statement of the American Diabetes Association, the North American Association for the Study of Obesity, and the American Society for Clinical Nutrition
    • Klein S, Sheard NF, Pi-Sunyer X, Daly A, Wylie-Rosett J, Kulkarni K, Clark NG. Weight Management Through Lifestyle Modification for the Prevention and Management of Type 2 Diabetes: rationale and Strategies: A statement of the American Diabetes Association, the North American Association for the Study of Obesity, and the American Society for Clinical Nutrition. Diabetes Care. 2004;27(8):2067-73.
    • (2004) Diabetes Care , vol.27 , Issue.8 , pp. 2067-2073
    • Klein, S.1    Sheard, N.F.2    Pi-Sunyer, X.3    Daly, A.4    Wylie-Rosett, J.5    Kulkarni, K.6    Clark, N.G.7
  • 10
    • 15944424370 scopus 로고    scopus 로고
    • Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program
    • The Diabetes Prevention Program Research G. Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program. Diabetes Care. 2005;28(4):888-94.
    • (2005) Diabetes Care , vol.28 , Issue.4 , pp. 888-894
  • 11
    • 0036517849 scopus 로고    scopus 로고
    • The evidence for the effectiveness of medical nutrition therapy in diabetes management
    • Pastors JG, Warshaw H, Daly A, Franz M, Kulkarni K. The evidence for the effectiveness of medical nutrition therapy in diabetes management. Diabetes Care. 2002;25(3):608-13.
    • (2002) Diabetes Care , vol.25 , Issue.3 , pp. 608-613
    • Pastors, J.G.1    Warshaw, H.2    Daly, A.3    Franz, M.4    Kulkarni, K.5
  • 14
    • 84930465070 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2015
    • American Diabetes Association. Standards of medical care in diabetes-2015. Diabetes Care. 2015;38(Suppl 1):S1-93.
    • (2015) Diabetes Care , vol.38 , pp. S1-S93
  • 15
    • 84862586269 scopus 로고    scopus 로고
    • The reference framework for diabetes care in primary care settings
    • Wong M, Sin C, Lee J. The reference framework for diabetes care in primary care settings. Hong Kong Med J. 2012;18(3):238-46.
    • (2012) Hong Kong Med J , vol.18 , Issue.3 , pp. 238-246
    • Wong, M.1    Sin, C.2    Lee, J.3
  • 16
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • Turner RC, Holman RR, Stratton IM, Cull CA, et al. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet. 1998;352(9131):854-65.
    • (1998) Lancet , vol.352 , Issue.9131 , pp. 854-865
    • Turner, R.C.1    Holman, R.R.2    Stratton, I.M.3    Cull, C.A.4
  • 17
    • 33746588255 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the american diabetes association and the european association for the study of diabetes
    • Nathan DM, Buse JB, Davidson MB, Heine RJ, Holman RR, Sherwin R, Zinman B. Management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the american diabetes association and the european association for the study of diabetes. Diabetes Care. 2006;29(8):1963-72.
    • (2006) Diabetes Care , vol.29 , Issue.8 , pp. 1963-1972
    • Nathan, D.M.1    Buse, J.B.2    Davidson, M.B.3    Heine, R.J.4    Holman, R.R.5    Sherwin, R.6    Zinman, B.7
  • 18
    • 55949101986 scopus 로고    scopus 로고
    • The design of a decision aid about diabetes medications for use during the consultation with patients with type 2 diabetes
    • Breslin M, Mullan RJ, Montori VM. The design of a decision aid about diabetes medications for use during the consultation with patients with type 2 diabetes. Patient Educ Couns. 2008;73(3):465-72.
    • (2008) Patient Educ Couns , vol.73 , Issue.3 , pp. 465-472
    • Breslin, M.1    Mullan, R.J.2    Montori, V.M.3
  • 19
    • 35148821008 scopus 로고    scopus 로고
    • Patient perceptions of quality of life with diabetes-related complications and treatments
    • Huang ES, Brown SES, Ewigman BG, Foley EC, Meltzer DO. Patient perceptions of quality of life with diabetes-related complications and treatments. Diabetes Care. 2007;30(10):2478-83.
    • (2007) Diabetes Care , vol.30 , Issue.10 , pp. 2478-2483
    • Huang, E.S.1    Brown, S.E.S.2    Ewigman, B.G.3    Foley, E.C.4    Meltzer, D.O.5
  • 20
    • 84870345888 scopus 로고    scopus 로고
    • Evaluation of the quality of care of a multi-disciplinary risk factor assessment and management programme (RAMP) for diabetic patients
    • Fung CS, Chin WY, Dai DS, Kwok RL, Tsui EL, Wan YF, Wong W, Wong CK, Fong DY, Lam CL. Evaluation of the quality of care of a multi-disciplinary risk factor assessment and management programme (RAMP) for diabetic patients. BMC Fam Pract. 2012;13(1):116.
    • (2012) BMC Fam Pract , vol.13 , Issue.1 , pp. 116
    • Fung, C.S.1    Chin, W.Y.2    Dai, D.S.3    Kwok, R.L.4    Tsui, E.L.5    Wan, Y.F.6    Wong, W.7    Wong, C.K.8    Fong, D.Y.9    Lam, C.L.10
  • 21
    • 39449138964 scopus 로고    scopus 로고
    • British national formulary
    • London: Pharmaceutical Press.
    • Joint Formulary Committee and Royal Pharmaceutical Society of Great Britain. British national formulary. London: Pharmaceutical Press; 2012.
    • (2012)
  • 22
    • 84943518099 scopus 로고    scopus 로고
    • Hong Kong health service delivery profile
    • 6 Oct 2015.
    • World Health Organization and Department of Health HKSAR. Hong Kong health service delivery profile. 2012. http://www.wpro.who.int/health_services/service:delivery_profile_hong_kong_(china).pdf?ua=1. Retrieved 6 Oct 2015.
    • (2012)
  • 23
    • 85028663692 scopus 로고    scopus 로고
    • Health Facts of Hong Kong
    • 6 Oct 2015.
    • Department of Health HKSAR. Health Facts of Hong Kong. 2014. http://www.dh.gov.hk/english/statistics/statistics_hs/files/Health_Statistics_pamphlet_E.pdf. Retrieved 6 Oct 2015.
    • (2014)
  • 24
    • 0025268851 scopus 로고
    • Simple method to calculate the confidence interval of a standardized mortality ratio (SMR)
    • Ulm K. Simple method to calculate the confidence interval of a standardized mortality ratio (SMR). Am J Epidemiol. 1990;131(2):373-5.
    • (1990) Am J Epidemiol , vol.131 , Issue.2 , pp. 373-375
    • Ulm, K.1
  • 25
    • 0030069896 scopus 로고    scopus 로고
    • Tutorial in biostatistics multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors
    • Harrell F, Lee KL, Mark DB. Tutorial in biostatistics multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med. 1996;15:361-87.
    • (1996) Stat Med , vol.15 , pp. 361-387
    • Harrell, F.1    Lee, K.L.2    Mark, D.B.3
  • 26
    • 0036788380 scopus 로고    scopus 로고
    • Use of complementary and alternative medicine among persons with diabetes mellitus: results of a national survey
    • Yeh GY, Eisenberg DM, Davis RB, Phillips RS. Use of complementary and alternative medicine among persons with diabetes mellitus: results of a national survey. Am J Public Health. 2002;92(10):1648-52.
    • (2002) Am J Public Health , vol.92 , Issue.10 , pp. 1648-1652
    • Yeh, G.Y.1    Eisenberg, D.M.2    Davis, R.B.3    Phillips, R.S.4
  • 27
    • 79955117591 scopus 로고    scopus 로고
    • Traditional Chinese Medicines in Treatment of Patients with Type 2 Diabetes Mellitus
    • Xie W, Zhao Y, Zhang Y. Traditional Chinese Medicines in Treatment of Patients with Type 2 Diabetes Mellitus. Evid Based Complement Alternat Med. 2011;2011:13.
    • (2011) Evid Based Complement Alternat Med. , vol.2011 , pp. 13
    • Xie, W.1    Zhao, Y.2    Zhang, Y.3
  • 28
    • 0036479746 scopus 로고    scopus 로고
    • The prevalence and pattern of complementary and alternative medicine use in individuals with diabetes
    • Egede LE, Ye X, Zheng D, Silverstein MD. The prevalence and pattern of complementary and alternative medicine use in individuals with diabetes. Diabetes Care. 2002;25(2):324-9.
    • (2002) Diabetes Care , vol.25 , Issue.2 , pp. 324-329
    • Egede, L.E.1    Ye, X.2    Zheng, D.3    Silverstein, M.D.4
  • 29
    • 34249875395 scopus 로고    scopus 로고
    • How doctors choose medications to treat type 2 diabetes: a national survey of specialists and academic generalists
    • Grant RW, Wexler DJ, Watson AJ, Lester WT, Cagliero E, Campbell EG, Nathan DM. How doctors choose medications to treat type 2 diabetes: a national survey of specialists and academic generalists. Diabetes Care. 2007;30(6):1448-53.
    • (2007) Diabetes Care , vol.30 , Issue.6 , pp. 1448-1453
    • Grant, R.W.1    Wexler, D.J.2    Watson, A.J.3    Lester, W.T.4    Cagliero, E.5    Campbell, E.G.6    Nathan, D.M.7
  • 30
    • 0034878676 scopus 로고    scopus 로고
    • Patient compliance and persistence with antihyperglycemic drug regimens: evaluation of a medicaid patient population with type 2 diabetes mellitus
    • Dailey G, Kim MS, Lian JF. Patient compliance and persistence with antihyperglycemic drug regimens: evaluation of a medicaid patient population with type 2 diabetes mellitus. Clin Ther. 2001;23(8):1311-20.
    • (2001) Clin Ther , vol.23 , Issue.8 , pp. 1311-1320
    • Dailey, G.1    Kim, M.S.2    Lian, J.F.3
  • 31
    • 0032515775 scopus 로고    scopus 로고
    • Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS: 23)
    • Turner R, Millns H, Neil H, Stratton I, Manley S, Matthews D, Holman R. Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS: 23). BMJ. 1998;316(7134):823-8.
    • (1998) BMJ , vol.316 , Issue.7134 , pp. 823-828
    • Turner, R.1    Millns, H.2    Neil, H.3    Stratton, I.4    Manley, S.5    Matthews, D.6    Holman, R.7
  • 32
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
    • Stratton IM, Adler AI, Neil HAW, Matthews DR, Manley SE, Cull CA, Hadden D, Turner RC, Holman RR. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000;321(7258):405-12.
    • (2000) BMJ , vol.321 , Issue.7258 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.W.3    Matthews, D.R.4    Manley, S.E.5    Cull, C.A.6    Hadden, D.7    Turner, R.C.8    Holman, R.R.9
  • 33
    • 0031614038 scopus 로고    scopus 로고
    • Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes
    • Lee A, Morley JE. Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes. Obes Res. 1998;6(1):47-53.
    • (1998) Obes Res , vol.6 , Issue.1 , pp. 47-53
    • Lee, A.1    Morley, J.E.2
  • 34
    • 0029133235 scopus 로고
    • Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
    • Stumvoll M, Nurjhan N, Perriello G, Dailey G, Gerich JE. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med. 1995;333(9):550-4.
    • (1995) N Engl J Med , vol.333 , Issue.9 , pp. 550-554
    • Stumvoll, M.1    Nurjhan, N.2    Perriello, G.3    Dailey, G.4    Gerich, J.E.5
  • 37
    • 84920841479 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase by metformin protects human coronary artery endothelial cells against diabetic lipoapoptosis
    • Eriksson L, Nyström T. Activation of AMP-activated protein kinase by metformin protects human coronary artery endothelial cells against diabetic lipoapoptosis. Cardiovasc Diabetol. 2014;13(1):152.
    • (2014) Cardiovasc Diabetol , vol.13 , Issue.1 , pp. 152
    • Eriksson, L.1    Nyström, T.2
  • 38
    • 84889030469 scopus 로고    scopus 로고
    • Effects of two weeks of metformin treatment on whole-body glycocalyx barrier properties in db/db mice
    • Eskens BJ, Zuurbier CJ, van Haare J, Vink H, van Teeffelen JW. Effects of two weeks of metformin treatment on whole-body glycocalyx barrier properties in db/db mice. Cardiovasc Diabetol. 2013;12(1):175.
    • (2013) Cardiovasc Diabetol , vol.12 , Issue.1 , pp. 175
    • Eskens, B.J.1    Zuurbier, C.J.2    Haare, J.3    Vink, H.4    Teeffelen, J.W.5
  • 39
    • 84930762844 scopus 로고    scopus 로고
    • Metformin inhibits monocyte-to-macrophage differentiation via ampk-mediated inhibition of STAT3 activation: potential role in atherosclerosis
    • Vasamsetti SB, Karnewar S, Kanugula AK, Thatipalli AR, Kumar JM, Kotamraju S. Metformin inhibits monocyte-to-macrophage differentiation via ampk-mediated inhibition of STAT3 activation: potential role in atherosclerosis. Diabetes. 2015;64(6):2028-41.
    • (2015) Diabetes , vol.64 , Issue.6 , pp. 2028-2041
    • Vasamsetti, S.B.1    Karnewar, S.2    Kanugula, A.K.3    Thatipalli, A.R.4    Kumar, J.M.5    Kotamraju, S.6
  • 40
    • 84875825054 scopus 로고    scopus 로고
    • The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats
    • Lu J, Ji J, Meng H, Wang D, Jiang B, Liu L, Randell E, Adeli K, Meng QH. The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. Cardiovasc Diabetol. 2013;12:58.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 58
    • Lu, J.1    Ji, J.2    Meng, H.3    Wang, D.4    Jiang, B.5    Liu, L.6    Randell, E.7    Adeli, K.8    Meng, Q.H.9
  • 41
    • 84924853787 scopus 로고    scopus 로고
    • Metformin attenuates myocardial remodeling and neutrophil recruitment after myocardial infarction in rat
    • Soraya H, Rameshrad M, Mokarizadeh A, Garjani A. Metformin attenuates myocardial remodeling and neutrophil recruitment after myocardial infarction in rat. BioImpacts BI. 2015;5(1):3.
    • (2015) BioImpacts BI , vol.5 , Issue.1 , pp. 3
    • Soraya, H.1    Rameshrad, M.2    Mokarizadeh, A.3    Garjani, A.4
  • 42
    • 84908068320 scopus 로고    scopus 로고
    • Association of metformin with lower atrial fibrillation risk among patients with type 2 diabetes mellitus: a population-based dynamic cohort and in vitro studies
    • Chang S-H, Wu L-S, Chiou M-J, Liu J-R, Yu K-H, Kuo C-F, Wen M-S, Chen W-J, Yeh Y-H, See L-C. Association of metformin with lower atrial fibrillation risk among patients with type 2 diabetes mellitus: a population-based dynamic cohort and in vitro studies. Cardiovasc Diabetol. 2014;13:123.
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 123
    • Chang, S.-H.1    Wu, L.-S.2    Chiou, M.-J.3    Liu, J.-R.4    Yu, K.-H.5    Kuo, C.-F.6    Wen, M.-S.7    Chen, W.-J.8    Yeh, Y.-H.9    See, L.-C.10
  • 43
    • 78851470539 scopus 로고    scopus 로고
    • Effect of metformin on cardiovascular events and mortality: a meta-analysis of randomized clinical trials
    • Lamanna C, Monami M, Marchionni N, Mannucci E. Effect of metformin on cardiovascular events and mortality: a meta-analysis of randomized clinical trials. Diabetes Obes Metab. 2011;13(3):221-8.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.3 , pp. 221-228
    • Lamanna, C.1    Monami, M.2    Marchionni, N.3    Mannucci, E.4
  • 45
    • 0027399661 scopus 로고
    • Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects: a study of two ethnic groups
    • Nagi DK, Yudkin JS. Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects: a study of two ethnic groups. Diabetes Care. 1993;16(4):621-9.
    • (1993) Diabetes Care , vol.16 , Issue.4 , pp. 621-629
    • Nagi, D.K.1    Yudkin, J.S.2
  • 46
    • 77953929752 scopus 로고    scopus 로고
    • Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial
    • de Jager J, Kooy A, Lehert P, Wulffelé MG, van der Kolk J, Bets D, Verburg J, Donker AJM, Stehouwer CDA. Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial. BMJ. 2010;340:c2181.
    • (2010) BMJ , vol.340 , pp. c2181
    • de Jager, J.1    Kooy, A.2    Lehert, P.3    Wulffelé, M.G.4    van der Kolk, J.5    Bets, D.6    Verburg, J.7    Donker, A.J.M.8    Stehouwer, C.D.A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.