The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats

Cardiovascular Diabetology

Volumn 12, Issue 1, 2013, Pages

  Lu, Jianxin ^a,b   Ji, Jingzhang ^a,b   Meng, Howard ^c   Wang, David ^c   Jiang, Bo ^d   Liu, Lixin ^d   Randell, Edward ^e   Adeli, Khosrow ^c   Meng, Qing H ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF SASKATCHEWAN   (Canada)

^e MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Insulin resistance; Metformin; Methylglyoxal; Neointimal hyperplasia; Rat

Indexed keywords

CHOLESTEROL; FATTY ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; METHYLGLYOXAL; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; ANTIDIABETIC AGENT; FRUCTOSE; GLUCOSE BLOOD LEVEL; PROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; HEART WEIGHT; INSULIN BLOOD LEVEL; KIDNEY MASS; LIVER WEIGHT; MALE; NEOINTIMA; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; VASOCONSTRICTION; VASODILATATION; ANIMAL; BLOOD; CAROTID ARTERY; CAROTID ARTERY INJURY; CAROTID ARTERY OBSTRUCTION; CELL CULTURE; CENTRAL VENOUS CATHETER; CYTOLOGY; DRUG EFFECTS; INSULIN RESISTANCE; PATHOLOGY; SMOOTH MUSCLE FIBER; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE; WOUND HEALING;

ANIMALS; BLOOD GLUCOSE; CAROTID ARTERIES; CAROTID ARTERY INJURIES; CAROTID STENOSIS; CELLS, CULTURED; CHOLESTEROL; FATTY ACIDS, NONESTERIFIED; FRUCTOSE; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MALE; METFORMIN; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOINTIMA; PROTECTIVE AGENTS; PYRUVALDEHYDE; RATS; RATS, SPRAGUE-DAWLEY; TRIGLYCERIDES; VASCULAR ACCESS DEVICES; WOUND HEALING;

EID: 84875825054     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-12-58     Document Type: Article

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