Corin is down-regulated and exerts cardioprotective action via activating pro-atrial natriuretic peptide pathway in diabetic cardiomyopathy

Cardiovascular Diabetology

Volumn 14, Issue 1, 2015, Pages

  Pang, Aiming ^b   Hu, Yahui ^a   Zhou, Pengfei ^a   Long, Guangfeng ^a   Tian, Xin ^a   Men, Li ^a   Shen, Yanna ^a   Liu, Yunde ^a   Cui, Yujie ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

Author keywords

Atrial natriuretic peptide; Corin; Diabetic cardiomyopathy

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CORIN PROTEIN; GLUCOSE; ISOLECTIN B4; PRO ATRIAL NATRIURETIC PEPTIDE; SERINE PROTEINASE; UNCLASSIFIED DRUG; CORIN PROTEIN, RAT; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANP GENE; ARTERIOLE; ARTICLE; ASSAY; CAPILLARY ENDOTHELIUM; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CORIN GENE; DIABETIC CARDIOMYOPATHY; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; GENE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HEART MUSCLE CELL; HEART PROTECTION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MTT ASSAY; MYOBLAST; NEWBORN; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VASCULAR REMODELING; WESTERN BLOTTING; WOUND HEALING SCRATCH ASSAY; ANIMAL; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; COMPLICATION; DIABETIC CARDIOMYOPATHIES; EXPERIMENTAL DIABETES MELLITUS; GENETICS; METABOLISM; SPRAGUE DAWLEY RAT; WOUND HEALING;

ANIMALS; ATRIAL NATRIURETIC FACTOR; BLOTTING, WESTERN; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DOWN-REGULATION; IMMUNOHISTOCHEMISTRY; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SERINE ENDOPEPTIDASES; WOUND HEALING;

EID: 84943514438     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-015-0298-9     Document Type: Article

References (38)

1. King H, Aubert RE, Herman WH. Global burden of diabetes 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care. 1998;21(9):1414-31.
2. Tarquini R, Lazzeri C, Pala L, Rotella CM, Gensini GF. The diabetic cardiomyopathy. Acta Diabetol. 2011;48(3):173-81.
3. Garcia MJ, McNamara PM, Gordon T, Kannel WB. Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study. Diabetes. 1974;23(2):105-11.
4. Wu Q, Xu-Cai YO, Chen S, Wang W. Corin: new insights into the natriuretic peptide system. Kidney Int. 2009;75(2):142-6.
5. Wu Q, Kuo HC, Deng GG. Serine proteases and cardiac function. Biochim Biophys Acta. 2005;1751(1):82-94.
6. Yan W, Sheng N, Seto M, Morser J, Wu Q. Corin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart. J Biol Chem. 1999;274(21):14926-35.
7. Wu Q. The serine protease corin in cardiovascular biology and disease. Front Biosci. 2007;12:4179-90.
8. Yan W, Wu F, Morser J, Wu Q. Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme. Proc Natl Acad Sci USA. 2000;97(15):8525-9.
9. Chan JC, Knudson O, Wu F, Morser J, Dole WP, Wu Q. Hypertension in mice lacking the proatrial natriuretic peptide convertase corin. Proc Natl Acad Sci USA. 2005;102(3):785-90.
10. Wang W, Shen J, Cui Y, Jiang J, Chen S, Peng J, et al. Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice. Kidney Int. 2012;82(1):26-33.
11. Ibebuogu UN, Gladysheva IP, Houng AK, Reed GL. Decompensated heart failure is associated with reduced corin levels and decreased cleavage of pro-atrial natriuretic peptide. Circ Heart Fail. 2011;4(2):114-20.
12. Nicholls SJ, Tuzcu EM, Kalidindi S, Wolski K, Moon KW, Sipahi I, et al. Effect of diabetes on progression of coronary atherosclerosis and arterial remodeling: a pooled analysis of 5 intravascular ultrasound trials. J Am Coll Cardiol. 2008;52(4):255-62.
13. Joshi M, Kotha SR, Malireddy S, Selvaraju V, Satoskar AR, Palesty A, et al. Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular endothelial dysfunction, reactive oxygen species, and mitochondria. Mol Cell Biochem. 2014;386(1-2):233-49.
14. Cui Y, Wang W, Dong N, Lou J, Srinivasan DK, Cheng W, et al. Role of corin in trophoblast invasion and uterine spiral artery remodeling in pregnancy. Nature. 2012;484(7393):246-50.
15. Kook H, Itoh H, Choi BS, Sawada N, Doi K, Hwang TJ, et al. Physiological concentration of atrial natriuretic peptide induces endothelial regeneration in vitro. Am J Physiol Heart Circ Physiol. 2003;284:1388-97.
16. Rubattu S, Sciarretta S, Valenti V, Stanzione R, Volpe M. Natriuretic peptides: an update on bioactivity, potential therapeutic use, and implication in cardiovascular diseases. Am J Hypertens. 2008;21(7):733-41.
17. Langenickel TH, Pagel I, Buttgereit J, Tenner K, Lindner M, Dietz R, et al. Rat corin gene molecular cloning and reduced expression in experimental heart failure. Am J Physiol Heart Circ Physiol. 2004;287(4):H1516-21.
18. Wang W, Cui Y, Shen J, Jiang J, Chen S, Peng J, et al. Salt-sensitive hypertension and cardiac hypertrophy in transgenic mice expressing a corin variant identified in blacks. Hypertension. 2012;60(5):1352-8.
19. Peleg A, Ghanim D, Vered S, Hasin Y. Serum corin is reduced and predicts adverse outcome in non-ST-elevation acute coronary syndrome. Eur Heart J Acute Cardiovasc Care. 2013;2(2):159-65.
20. Barnet CS, Liu X, Body SC, Collard CD, Shernan SK, Muehlschlegel JD, et al. Plasma corin decreases after coronary artery bypass graft surgery and is associated with postoperative heart failure: a pilot study. J Cardiothorac Vasc Anesth. 2015;29(2):374-81.
21. Gladysheva IP, Wang D, McNamee RA, Houng AK, Mohamad AA, Fan TM, et al. Corin overexpression improves cardiac function, heart failure, and survival in mice with dilated cardiomyopathy. Hypertension. 2013;61(2):327-32.
22. Tarazón E, Roselló-Lletí E, Rivera M, Ortega A, Molina-Navarro MM, Triviño JC, et al. RNA sequencing analysis and atrial natriuretic peptide production in patients with dilated and ischemic cardiomyopathy. PLoS One. 2014;9(3):e90157.
23. Chen S, Sen S, Young D, Wang W, Moravec CS, Wu Q. Protease corin expression and activity in failing hearts. Am J Physiol Heart Circ Physiol. 2010;299(5):H1687-92.
24. Chen S, Cao P, Dong N, Peng J, Zhang C, Wang H, et al. PCSK6-mediated corin activation is essential for normal blood pressure. Nat Med. 2015;21(9):1048-53.
25. Polzin D, Kaminski HJ, Kastner C, Wang W, Kramer S, Gambaryan S, et al. Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases. Kidney Int. 2010;78(7):650-9.
26. Zhou H, Liu W, Zhu J, Liu M, Fang C, Wu Q, et al. Reduced serum corin levels in patients with osteoporosis. Clin Chim Acta. 2013;426:152-6.
27. Wu F, Wu Q. Corin-mediated processing of pro-atrial natriuretic peptide in human small cell lung cancer cells. Cancer Res. 2003;63(23):8318-22.
28. Peng H, Zhang Q, Shen HS, Liu Y, Chao XQ, Tian HG, et al. Association between serum soluble corin and obesity in Chinese adults: a cross-sectional study. Obesity. 2015;23(4):856-61.
29. Gutkowska J, Broderick TL, Bogdan D, Wang D, Lavoie JM, Jankowski M. Downregulation of oxytocin and natriuretic peptides in diabetes: possible implications in cardiomyopathy. J Physiol. 2009;587(Pt 19):4725-36.
30. Wang D, Gladysheva IP, Fan TH, Sullivan R, Houng AK, Reed GL. Atrial natriuretic peptide affects cardiac remodeling, function, heart failure, and survival in a mouse model of dilated cardiomyopathy. Hypertension. 2014;63(3):514-9.
31. Nakagawa H, Oberwinkler H, Nikolaev VO, Gassner B, Umbenhauer S, Wagner H, et al. Atrial natriuretic peptide locally counteracts the deleterious effects of cardiomyocyte mineralocorticoid receptor activation. Circ Heart Fail. 2014;7(5):814-21.
32. Fujita S, Shimojo N, Terasaki F, Otsuka K, Hosotani N, Kohda Y, et al. Atrial natriuretic peptide exerts protective action against angiotensin II-induced cardiac remodeling by attenuating inflammation via endothelin-1/endothelin receptor A cascade. Heart Vessels. 2013;28(5):646-57.
33. Song W, Wang H, Wu Q. Atrial natriuretic peptide in cardiovascular biology and disease(NPPA). Gene. 2015;569(1):1-6.
34. Rosa CM, Xavier NP, Campos DH, Fernandes AAH, Cezar MDM, Martinez PF, et al. Diabetes mellitus activates fetal gene programand intensifies cardiac remodeling and oxidativestress in aged spontaneously hypertensive rats. Cardiovasc Diabetol. 2013;12:152.
35. Potenza MA, Gagliardi S, Nacci C, Carratu MR, Montagnani M. Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets. Curr Med Chem. 2009;16(1):94-112.
36. Yoon YS, Uchida S, Masuo O, Cejna M, Park JS, Gwon HC, et al. Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor. Circulation. 2005;111(16):2073-85.
37. Kuhn Michaela, Völker Katharina, Schwarz Kristine, Carbajo-Lozoya Javier, Flögel Ulrich, Jacoby Christoph, et al. The natriuretic peptide/guanylyl cyclase-a system functions as a stress-responsive regulator of angiogenesis in mice. J Clin Invest. 2009;119(7):2019-30.
38. Tokudome T, Kishimoto I, Yamahara K, Osaki T, Minamino N, Horio T, et al. Impaired recovery of blood flow after hind-limb ischemia in mice lacking guanylyl cyclase-A, a receptor for atrial and brain natriuretic peptides. Arterioscler Thromb Vasc Biol. 2009;29(10):1516-21.