Impaired recovery of blood flow after hind-limb ischemia in mice lacking guanylyl cyclase-a, a receptor for atrial and brain natriuretic peptides

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 10, 2009, Pages 1516-1521

  Tokudome, Takeshi ^a   Kishimoto, Ichiro ^a   Yamahara, Kenichi ^a   Osaki, Tsukasa ^a   Minamino, Naoto ^a   Horio, Takeshi ^a   Sawai, Kazutomo ^a   Kawano, Yuhei ^a   Miyazato, Mikiya ^a   Sata, Masataka ^b   Kohno, Masakazu ^c   Nakao, Kazuwa ^d   Kangawa, Kenji ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c KAGAWA UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Atrial natriuretic peptide; Brain natriuretic peptide; Guanylyl cyclase A; Ischemia; Mice

Indexed keywords

ANTIBODY; ATRIAL NATRIURETIC FACTOR; ATRIAL NATRIURETIC FACTOR RECEPTOR; BRAIN NATRIURETIC PEPTIDE; BRAIN NATRIURETIC PEPTIDE RECEPTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HORMONE RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NATRIURETIC PEPTIDE RECEPTOR A; PECAM 1 ANTIBODY; UNCLASSIFIED DRUG; VASCULOTROPIN; ACTIN BINDING PROTEIN; CELL ADHESION MOLECULE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN; VASCULOTROPIN A; VASODILATOR STIMULATED PHOSPHOPROTEIN; VASODILATOR-STIMULATED PHOSPHOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW TRANSPLANTATION; CAPILLARY DENSITY; CONTROLLED STUDY; CONVALESCENCE; ENDOTHELIUM CELL; HINDLIMB; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LASER DOPPLER FLOWMETRY; LIMB AMPUTATION; LIMB BLOOD FLOW; LIMB ISCHEMIA; LIMB PERFUSION; MALE; MOUSE; NONHUMAN; OBSERVATIONAL STUDY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL MOBILIZATION; STRAIN DIFFERENCE; ULCER; WILD TYPE; ANIMAL; BLOOD FLOW; BLOOD VESSEL; CELL CULTURE; GENETICS; ISCHEMIA; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REGENERATION; VASCULARIZATION;

ANIMALS; ATRIAL NATRIURETIC FACTOR; BLOOD VESSELS; CELL ADHESION MOLECULES; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HINDLIMB; HUMANS; ISCHEMIA; MALE; MICE; MICROFILAMENT PROTEINS; NATRIURETIC PEPTIDE, BRAIN; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHOPROTEINS; RECEPTORS, ATRIAL NATRIURETIC FACTOR; REGENERATION; REGIONAL BLOOD FLOW; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 70349569049     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.187526     Document Type: Article

References (21)

1. Lee SH, Wolf PL, Escudero R, Deutsch R, Jamieson SW, Thistlethwaite PA. Early expression of angiogenesis factors in acute myocardial ischemia and infarction. N Engl J Med. 2000;342:626-633.
2. Murohara T, Asahara T, Silver M, Bauters C, Masuda H, Kalka C, Kearney M, Chen D, Symes JF, Fishman MC, Huang PL, Isner JM. Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest. 1998;101:2567-2578.
3. Nakao K, Itoh H, Saito Y, Mukoyama M, Ogawa Y. The natriuretic peptide family. Curr Opin Nephrol Hypertens. 1996;5:4-11.
4. Yamahara K, Itoh H, Chun TH, Ogawa Y, Yamashita J, Sawada N, Fukunaga Y, Sone M, Yurugi-Kobayashi T, Miyashita M, Tsujimoto H, Kook H, Feil R, Garbers DL, Hofmann F, Nakao K. Significance and therapeutic potential of the natriuretic peptides/cGMP/cGMP-dependent protein kinase pathway in vascular regeneration. Proc Natl Acad Sci U S A. 2003;100:3404-3409.
5. Park K, Itoh H, Yamahara K, Sone M, Miyashita K, Oyamada N, Sawada N, Taura D, Inuzuka M, Sonoyama T, Tsujimoto H, Fukunaga Y, Tamura N, Nakao K. Therapeutic potential of atrial natriuretic peptide administration on peripheral arterial diseases. Endocrinology. 2008;149: 483-491.
6. Lopez MJ, Wong SK, Kishimoto I, Dubois S, Mach V, Friesen J, Garbers DL, Beuve A. Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide. Nature. 1995;378:65-68.
7. Couffinhal T, Silver M, Zheng LP, Keamey M, Witzenbichler B, Isner JM. Mouse model of angiogenesis. Am J pathol. 1998;152:1667-1679.
8. Minamino N, Aburaya M, Kojima M, Miyamoto K, Kangawa K, Matsuo H. Distribution of C-type natriuretic peptide and its messenger RNA in rat central nervous system and peripheral tissue. Biochem Biophys Res Commun. 1993;197:326-335.
9. Sata M, Saiura A, Kunisato A, Tojo A, Okada S, Tokuhisa T, Hirai H, Makuuchi M, Hirata Y, Nagai R. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med. 2002;8:403-409.
10. Tokudome T, Kishimoto I, Horio T, Arai Y, Schwenke DO, Hino J, Okano I, Kawano Y, Kohno M, Miyazato M, Nakao K, Kangawa K. Regulator of G-protein signaling subtype 4 mediates antihypertrophic effect of locally secreted natriuretic peptides in the heart. Circulation. 2008;117:2329-2339.
11. Tokudome T, Horio T, Kishimoto I, Soeki T, Mori K, Kawano Y, Kohno M, Garbers DL, Nakao K, Kangawa K. Calcineurin-nuclear factor of activated T cells pathway-dependent cardiac remodeling in mice deficient in guanylyl cyclase A, a receptor for atrial and brain natriuretic peptides. Circulation. 2005;111:3095-3104.
12. Urbich C, Dimmeler S. Endothelial progenitor cells: characterization and role in vascular biology. Circ Res. 2004;95:343-353. (Pubitemid 39100452)
13. Chen ZP, Mitchelhill KI, Michell BJ, Stapleton D, Rodriguez-Crespo I, Witters LA, Power DA, Ortiz de Montellano PR, Kemp BE. AMP-activated protein kinase phosphorylation of endothelial NO synthase. FEBS Lett. 1999;443:285-289. (Pubitemid 29080812)
14. Price CJ, Brindle NP. Vasodilator-stimulated phosphoprotein is involved in stress-fiber and membrane ruffle formation in endothelial cells. Arte-rioscler Thromb Vasc Biol. 2000;20:2051-2056.
15. Izumi T, Saito Y, Kishimoto I, Harada M, Kuwahara K, Hamanaka I, Takahashi N, Kawakami R, Li Y, Takemura G, Fujiwara H, Garbers DL, Mochizuki S, Nakao K. Blockade of the natriuretic peptide receptor guanylyl cyclase-A inhibits NF-kappaB activation and alleviates myo-cardial ischemia/reperfusion injury. J Clin Invest. 2001;108:203-213.
16. Kook H, Itoh H, Choi BK, Sawada N, Doi K, Hwang TJ, Kim KK, Arai H, Baik YH, Nakao K. Physiological concentration of atrial natriuretic peptide induces endothelial regeneration in vitro. Am J Physiol Heart Circ Physiol. 2003;284:H1388-H1397.
17. Chen H, Levine YC, Golan DE, Michel T, Lin AJ. Atrial natriuretic peptide-initiated cGMP pathways regulate vasodilator-stimulated phos-phoprotein phosphorylation and angiogenesis in vascular endothelium. J Biol Chem. 2008;283:4439-4447.
18. Bear JE, Svitkina TM, Krause M, Schafer DA, Loureiro JJ, Strasser GA, Maly IV, Chaga OY, Cooper JA, Borisy GG, Gertler FB. Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility. Cell. 2002;109:509-521.
19. Suga S, Nakao K, Hosoda K, Mukoyama M, Ogawa Y, Shirakami G, Arai H, Saito Y, Kambayashi Y, Inouye K, Imura H. Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Endocrinology. 1992;130: 229-239.
20. Aburaya M, Minamino N, Kangawa K, Tanaka K, Matsuo H. Distribution and molecular forms of brain natriuretic peptide in porcine heart and blood. Biochem Biophys Res Commun. 1989;165:872-879.
21. Suzuki S, Yoshimura M, Nakayama M, Mizuno Y, Harada E, Ito T, Nakamura S, Abe K, Yamamuro M, Sakamoto T, Saito Y, Nakao K, Yasue H, Ogawa H. Plasma level of B-type natriuretic peptide as a prognostic marker after acute myocardial infarction: a long-term follow-up analysis. Circulation. 2004;110:1387-1391.