Angiogenic and Antiangiogenic Factors in Preterm Neonates Born to Mothers with and without Preeclampsia

American Journal of Perinatology

Volumn 32, Issue 12, 2015, Pages 1185-1190

  Hentges, Cláudia R ^a   Silveira, Rita C ^a   Procianoy, Renato S ^a  

^a HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

angiogenic factors; antiangiogenic factors; preeclampsia; prematurity; sFlt 1; VEGF

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; FLT1 PROTEIN, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ARTICLE; BIRTH WEIGHT; BLOOD SAMPLING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FETUS GROWTH; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOTHER; NEWBORN; PREECLAMPSIA; PREMATURE FETUS MEMBRANE RUPTURE; PREMATURITY; PRIORITY JOURNAL; RISK FACTOR; SMALL FOR DATE INFANT; VAGINAL DELIVERY; BLOOD; COMPARATIVE STUDY; MULTIVARIATE ANALYSIS; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATIONS;

BIRTH WEIGHT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MALE; MULTIVARIATE ANALYSIS; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATIONS; RISK FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 84943453525     PISSN: 07351631     EISSN: 10988785     Source Type: Journal    
DOI: 10.1055/s-0035-1552932     Document Type: Article

References (39)

1. Silasi M., Cohen B., Karumanchi S. A., Rana S. Abnormal placentation, angiogenic factors, and the pathogenesis of preeclampsia. Obstet Gynecol Clin North Am: 2010; 37 2 239 253
2. Lam C., Lim K. H., Karumanchi S. A. Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia. Hypertension: 2005; 46 5 1077 1085
3. Muy-Rivera M., Vadachkoria S., Woelk G. B., Qiu C., Mahomed K., Williams M. A. Maternal plasma VEGF, sVEGF-R1, and PlGF concentrations in preeclamptic and normotensive pregnant Zimbabwean women. Physiol Res: 2005; 54 6 611 622
4. Cerdeira A. S., Karumanchi S. A. Angiogenic factors in preeclampsia and related disorders. Cold Spring Harb Perspect Med: 2012; 2 11 pii: a006585
5. Ribatti D. The discovery of the placental growth factor and its role in angiogenesis: a historical review. Angiogenesis: 2008; 11 3 215 221
6. Hentges C. R., Silveira R. C., Ferrelli R. S., Procianoy R. S. Influence of maternal pre-eclampsia on VEGF/PlGF heterodimer levels in preterm infants. J Matern Fetal Neonatal Med: 2014; 14 1 6
7. Catarino C., Rebelo I., Belo L., et al. Fetal and maternal angiogenic/anti-angiogenic factors in normal and preeclamptic pregnancy. Growth Factors: 2009; 27 6 345 351
8. Staff A. C., Braekke K., Harsem N. K., Lyberg T., Holthe M. R. Circulating concentrations of sFlt1 (soluble fms-like tyrosine kinase 1) in fetal and maternal serum during preeclampsia. Eur J Obstet Gynecol Reprod Biol: 2005; 122 1 33 39
9. Rana S., Karumanchi S. A., Levine R. J., et al. Sequential changes in antiangiogenic factors in early pregnancy and risk of developing preeclampsia. Hypertension: 2007; 50 1 137 142
10. Erez O., Romero R., Espinoza J., et al. The change in concentrations of angiogenic and antiangiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the subsequent development of preeclampsia and small-for-gestational age. J Matern Fetal Neonatal Med: 2008; 21 5 279 287
11. Maynard S. E., Min J. Y., Merchan J., et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest: 2003; 111 5 649 658
12. Levine R. J., Maynard S. E., Qian C., et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med: 2004; 350 7 672 683
13. Vatten L. J., Eskild A., Nilsen T. I., Jeansson S., Jenum P. A., Staff A. C. Changes in circulating level of angiogenic factors from the first to second trimester as predictors of preeclampsia. Am J Obstet Gynecol: 2007; 196 3 239.e1 239.e6
14. Troisi R., Braekke K., Harsem N. K., Hyer M., Hoover R. N., Staff A. C. Blood pressure augmentation and maternal circulating concentrations of angiogenic factors at delivery in preeclamptic and uncomplicated pregnancies. Am J Obstet Gynecol: 2008; 199 6 653.e1 653.e10
15. Levine R. J., Lam C., Qian C., et al. CPEP Study Group. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med: 2006; 355 10 992 1005
16. Staff A. C., Harsem N. K., Braekke K., Hyer M., Hoover R. N., Troisi R. Maternal, gestational and neonatal characteristics and maternal angiogenic factors in normotensive pregnancies. Eur J Obstet Gynecol Reprod Biol: 2009; 143 1 29 33
17. Sunderji S., Gaziano E., Wothe D., et al. Automated assays for sVEGF R1 and PlGF as an aid in the diagnosis of preterm preeclampsia: a prospective clinical study. Am J Obstet Gynecol: 2010; 202 1 40.e1 40.e7
18. Furuya M., Kurasawa K., Nagahama K., et al. Disrupted balance of angiogenic and antiangiogenic signalings in preeclampsia. J Pregnancy: 2011; 2011 123717
19. Sibai B., Dekker G., Kupferminc M. Pre-eclampsia. Lancet: 2005; 365 9461 785 799
20. Alexander G. R., Himes J. H., Kaufman R. B., Mor J., Kogan M. A United States national reference for fetal growth. Obstet Gynecol: 1996; 87 2 163 168
21. Zin A., Florêncio T., Fortes Filho J. B., et al. Brazilian Society of Pediatrics, Brazilian Council of Ophthalmology and Brazilian Society of Pediatric Ophthalmology. Brazilian guidelines proposal for screening and treatment of retinopathy of prematurity (ROP). Arq Bras Oftalmol: 2007; 70 5 875 883
22. Pieh C., Agostini H., Buschbeck C., et al. VEGF-A, VEGFR-1, VEGFR-2 and Tie2 levels in plasma of premature infants: relationship to retinopathy of prematurity. Br J Ophthalmol: 2008; 92 5 689 693
23. Eklund A. Beeswarm: The bee swarm plot, an alternative to stripchart. R package version 0.1.1, 2011. Available at: http://CRAN.R-project.org/package=beeswarm. Accessed February 2, 2015
24. Boutsikou T., Malamitsi-Puchner A., Economou E., Boutsikou M., Puchner K. P., Hassiakos D. Soluble vascular endothelial growth factor receptor-1 in intrauterine growth restricted fetuses and neonates. Early Hum Dev: 2006; 82 4 235 239
25. van Beem R. T., Verloop R. E., Kleijer M., et al. Blood outgrowth endothelial cells from cord blood and peripheral blood: angiogenesis-related characteristics in vitro. J Thromb Haemost: 2009; 7 1 217 226
26. Khan I., Zhang L., Mohammed M., et al. Effects of Wharton's jelly-derived mesenchymal stem cells on neonatal neutrophils. J Inflamm Res: 2015; 8 1 8
27. Mashiloane C. D., Moodley J. Induction or caesarean section for preterm pre-eclampsia? J Obstet Gynaecol: 2002; 22 4 353 356
28. Zhang Y., Li W., Xiao J., Chen S. The complication and mode of delivery in Chinese women with severe preeclampsia: a retrospective study. Hypertens Pregnancy: 2014; 33 3 283 290
29. Jelin A. C., Cheng Y. W., Shaffer B. L., Kaimal A. J., Little S. E., Caughey A. B. Early-onset preeclampsia and neonatal outcomes. J Matern Fetal Neonatal Med: 2010; 23 5 389 392
30. Wang A., Holston A. M., Yu K. F., et al. Circulating anti-angiogenic factors during hypertensive pregnancy and increased risk of respiratory distress syndrome in preterm neonates. J Matern Fetal Neonatal Med: 2012; 25 8 1447 1452
31. Ozkan H., Cetinkaya M., Koksal N. Increased incidence of bronchopulmonary dysplasia in preterm infants exposed to preeclampsia. J Matern Fetal Neonatal Med: 2012; 25 12 2681 2685
32. Tang J. R., Karumanchi S. A., Seedorf G., Markham N., Abman S. H. Excess soluble vascular endothelial growth factor receptor-1 in amniotic fluid impairs lung growth in rats: linking preeclampsia with bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol: 2012; 302 1 L36 L46
33. Hansen A. R., Barnés C. M., Folkman J., McElrath T. F. Maternal preeclampsia predicts the development of bronchopulmonary dysplasia. J Pediatr: 2010; 156 4 532 536
34. Ozkan H., Cetinkaya M., Koksal N., Ozmen A., Ylldlz M. Maternal preeclampsia is associated with an increased risk of retinopathy of prematurity. J Perinat Med: 2011; 39 5 523 527
35. Tsao P. N., Wei S. C., Su Y. N., Chou H. C., Chen C. Y., Hsieh W. S. Excess soluble fms-like tyrosine kinase 1 and low platelet counts in premature neonates of preeclamptic mothers. Pediatrics: 2005; 116 2 468 472
36. Procianoy R. S., Silveira R. C., Mussi-Pinhata M. M., et al. Brazilian Network on Neonatal Research. Sepsis and neutropenia in very low birth weight infants delivered of mothers with preeclampsia. J Pediatr: 2010; 157 3 434 438, 438.e1
37. Åsvold B. O., Vatten L. J., Romundstad P. R., Jenum P. A., Karumanchi S. A., Eskild A. Angiogenic factors in maternal circulation and the risk of severe fetal growth restriction. Am J Epidemiol: 2011; 173 6 630 639
38. Taki A., Abe M., Komaki M., et al. Expression of angiogenesis-related factors and inflammatory cytokines in placenta and umbilical vessels in pregnancies with preeclampsia and chorioamnionitis/funisitis. Congenit Anom (Kyoto): 2012; 52 2 97 103
39. Malamitsi-Puchner A., Boutsikou T., Economou E., et al. Vascular endothelial growth factor and placenta growth factor in intrauterine growth-restricted fetuses and neonates. Mediators Inflamm: 2005; 2005 5 293 297