Skin test evaluation of a novel peptide carrier-based vaccine, BM32, in grass pollen-allergic patients

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 4, 2015, Pages 1101-1103.e8

  Niederberger, Verena ^a   Marth, Katharina ^a   Eckl Dorna, Julia ^a   Focke Tejkl, Margarete ^a   Weber, Milena ^a   Hemmer, Wolfgang ^b   Berger, Uwe ^a   Neubauer, Angela ^c   Stolz, Frank ^c   Henning, Rainer ^c   Valenta, Rudolf ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b FAZ Floridsdorf Allergy Centre   (Austria)

^c BIOMAY AG   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BM 32; EPITOPE; GRASS POLLEN VACCINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G ANTIBODY; PEPTIDE VACCINE; PETROLATUM; UNCLASSIFIED DRUG; PEPTIDE; VACCINE; VEGETABLE PROTEIN;

ALLERGIC ASTHMA; ANAPHYLAXIS; CONTROLLED STUDY; DRUG SAFETY; ERYTHEMA; GRASS POLLEN; GRASS POLLEN ALLERGY; HUMAN; IMMUNOTHERAPY; LETTER; POLLEN ALLERGY; PRIORITY JOURNAL; SKIN TEST; T LYMPHOCYTE; ADULT; CLINICAL TRIAL; DESENSITIZATION; FEMALE; MALE; PROCEDURES; RHINITIS, ALLERGIC, SEASONAL;

ADULT; DESENSITIZATION, IMMUNOLOGIC; FEMALE; HUMANS; MALE; PEPTIDES; PLANT PROTEINS; RHINITIS, ALLERGIC, SEASONAL; SKIN TESTS; VACCINES;

EID: 84943449846     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.03.034     Document Type: Article

References (11)

1. L. Jacobsen, B. Niggemann, S. Dreborg, H.A. Ferdousi, S. Halken, A. Host, and et al. Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study Allergy 62 2007 943 948
2. L. Winther, H.J. Malling, and H. Mosbech Allergen-specific immunotherapy in birch- and grass-pollen-allergic rhinitis, II: side-effects Allergy 55 2000 827 835
3. R. Valenta, R. Campana, K. Marth, and M. van Hage Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches J Int Med 272 2012 144 157
4. M. Larche Update on the current status of peptide immunotherapy J Allergy Clin Immunol 119 2007 906 909
5. V. Niederberger, F. Horak, S. Vrtala, S. Spitzauer, M.T. Krauth, P. Valent, and et al. Vaccination with genetically engineered allergens prevents progression of allergic disease Proc Natl Acad Sci U S A 101 2004 14677 14682
6. C. Pellaton, Y. Perrin, C. Boudousquie, N. Barbier, J. Wassenberg, G. Corradin, and et al. Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides Clin Transl Allergy 3 2013 17
7. M. Focke-Tejkl, M. Weber, K. Niespodziana, A. Neubauer, H. Huber, R. Henning, and et al. Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy J Allergy Clin Immunol 135 2015 1207 1217
8. K. Turjanmaa, U. Darsow, B. Niggemann, F. Rance, T. Vanto, and T. Werfel EAACI/GA2LEN position paper: present status of the atopy patch test Allergy 61 2006 1377 1384
9. M. Focke-Tejkl, M. Weber, K. Niespodziana, A. Neubauer, H. Huber, R. Henning, and et al. Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy J Allergy Clin Immunol 135 2015 1207 1217
10. I. Pree, J. Reisinger, M. Focke, S. Vrtala, G. Pauli, M. van Hage, and et al. Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man J Immunol 179 2007 5309 5316
11. M. Focke, K. Marth, S. Flicker, and R. Valenta Heterogeneity of commercial timothy grass pollen extracts Clin Exp Allergy 38 2008 1400 1408