-
1
-
-
84885724091
-
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer
-
Bindea G, Mlecnik B, Tosolini M et al (2013) Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer. Immunity 39:782–795
-
(2013)
Immunity
, vol.39
, pp. 782-795
-
-
Bindea, G.1
Mlecnik, B.2
Tosolini, M.3
-
2
-
-
84862903106
-
Safety and activity of anti-pd-l1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ et al (2012) Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 366:2455–2465
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
3
-
-
84858800620
-
The immune contexture in human tumours: Impact on clinical outcome
-
Fridman WH, Pagès F, Sautès-Fridman C et al (2012) The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 12:298–306
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 298-306
-
-
Fridman, W.H.1
Pagès, F.2
Sautès-Fridman, C.3
-
4
-
-
84890280907
-
Towards the introduction of the ‘immunoscore’ in the classification of malignant tumours
-
Galon J, Mlecnik B, Bindea G et al (2014) Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours. J Pathol 232(2):199–209
-
(2014)
J Pathol
, vol.232
, Issue.2
, pp. 199-209
-
-
Galon, J.1
Mlecnik, B.2
Bindea, G.3
-
5
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O’Day SJ, McDermott DF et al (2010) Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363:711–723
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O’Day, S.J.2
McDermott, D.F.3
-
6
-
-
0141815907
-
Tumor-specific immunological recognition of frameshift- mutated peptides in colon cancer with microsatellite instability
-
Ishikawa T, Fujita T, Suzuki Y et al (2003) Tumor-specific immunological recognition of frameshift- mutated peptides in colon cancer with microsatellite instability. Cancer Res 63:5564–5572
-
(2003)
Cancer Res
, vol.63
, pp. 5564-5572
-
-
Ishikawa, T.1
Fujita, T.2
Suzuki, Y.3
-
7
-
-
79960409792
-
Enhanced cancer immunotherapy using stat3- depleted dendritic cells with high th1-inducing ability and resistance to cancer cell-derived inhibitory factors
-
Iwata-Kajihara T, Sumimoto H et al (2011) Enhanced cancer immunotherapy using STAT3- depleted dendritic cells with high Th1-inducing ability and resistance to cancer cell-derived inhibitory factors. J Immunol 187:27–36
-
(2011)
J Immunol
, vol.187
, pp. 27-36
-
-
Iwata-Kajihara, T.1
Sumimoto, H.2
-
8
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos M, Levine BL, Porter DL et al (2011) T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 3:95
-
(2011)
Sci Transl Med
, vol.3
, pp. 95
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
-
9
-
-
0028316911
-
Cloning of the gene coding for a shared human melanoma antigen recognized by autologous t cells infiltrating into tumor
-
Kawakami Y, Eliyahu S, Delgado CH et al (1994a) Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc Natl Acad Sci U S A 91:3515–3519
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3515-3519
-
-
Kawakami, Y.1
Eliyahu, S.2
Delgado, C.H.3
-
10
-
-
0028298174
-
Identification of human melanoma antigen recognized by tumor infiltrating lymphocytes associated with in vivo tumor rejection
-
Kawakami Y, Eliyahu S, Delgado CH et al (1994b) Identification of human melanoma antigen recognized by tumor infiltrating lymphocytes associated with in vivo tumor rejection. Proc NatlAcad Sci U S A 91:6458–6462
-
(1994)
Proc Natlacad Sci U S A
, vol.91
, pp. 6458-6462
-
-
Kawakami, Y.1
Eliyahu, S.2
Delgado, C.H.3
-
11
-
-
0028302028
-
Identification of the immune dominant peptides of the mart-1 human melanoma antigen recognized by the majority of hla-a2 restricted tumor infiltrating lymphocytes
-
Kawakami Y, Eliyahu S, Sakaguchi K et al (1994c) Identification of the immune dominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2 restricted tumor infiltrating lymphocytes. J Exp Med 180:347–352
-
(1994)
J Exp Med
, vol.180
, pp. 347-352
-
-
Kawakami, Y.1
Eliyahu, S.2
Sakaguchi, K.3
-
12
-
-
0035865364
-
Isolation of a new melanoma antigen, mart-2, containing a mutated epitope recognized by autologous tumor infiltrating t lymphocytes
-
Kawakami Y, Wang X, Shofuda T et al (2001) Isolation of a new melanoma antigen, MART-2, containing a mutated epitope recognized by autologous tumor infiltrating T lymphocytes. J Immunol 166:2871–2877
-
(2001)
J Immunol
, vol.166
, pp. 2871-2877
-
-
Kawakami, Y.1
Wang, X.2
Shofuda, T.3
-
13
-
-
84932165409
-
Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor-associated microenvironments
-
Shurin M, Malyguine A, Umansky V, Dordrecht/Heidelberg/New York/London
-
Kawakami Y, Yaguchi T, Sumimoto H et al (2013a) Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor-associated microenvironments. In: Shurin M, Malyguine A, Umansky V (eds) Tumor immune environment. Dordrecht/Heidelberg/New York/London
-
(2013)
Tumor Immune Environment
-
-
Kawakami, Y.1
Yaguchi, T.2
Sumimoto, H.3
-
14
-
-
84891104809
-
Improvement of cancer immunotherapy by combining molecular targeted therapy
-
Kawakami Y, Yaguchi T, Sumimoto H et al (2013b) Improvement of cancer immunotherapy by combining molecular targeted therapy. Front Oncol 3:136
-
(2013)
Front Oncol
, vol.3
, pp. 136
-
-
Kawakami, Y.1
Yaguchi, T.2
Sumimoto, H.3
-
15
-
-
60649089997
-
Cancer metastasis is accelerated through immunosuppression during emt of cancer cell
-
Kudo-Saito C, Shirako H, Takeuchi T et al (2009) Cancer metastasis is accelerated through immunosuppression during EMT of cancer cell. Cancer Cell 16:195–206
-
(2009)
Cancer Cell
, vol.16
, pp. 195-206
-
-
Kudo-Saito, C.1
Shirako, H.2
Takeuchi, T.3
-
16
-
-
84876460178
-
Ccl2 is critical for immunosuppression to promote cancer metastasis
-
Kudo-Saito C, Shirako H, Ohike M et al (2012) CCL2 is critical for immunosuppression to promote cancer metastasis. Clin Exp Metastasis 30:393–405
-
(2012)
Clin Exp Metastasis
, vol.30
, pp. 393-405
-
-
Kudo-Saito, C.1
Shirako, H.2
Ohike, M.3
-
17
-
-
84899050715
-
Functional network pipeline reveals genetic determinants associated with in situ lymphocyte proliferation and survival of cancer patients
-
Mlecnik B, Bindea G, Angell HK et al (2014) Functional network pipeline reveals genetic determinants associated with in situ lymphocyte proliferation and survival of cancer patients. Sci Transl Med 6:228
-
(2014)
Sci Transl Med
, vol.6
, pp. 228
-
-
Mlecnik, B.1
Bindea, G.2
Angell, H.K.3
-
18
-
-
84894482571
-
Tgf-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression
-
Nakamura S, Yaguchi T, Kawamura N et al (2014) TGF-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression. J Immunother 37:63–72
-
(2014)
J Immunother
, vol.37
, pp. 63-72
-
-
Nakamura, S.1
Yaguchi, T.2
Kawamura, N.3
-
19
-
-
84902551922
-
Immunosuppression through constitutively activatednf-κb signaling in human ovarian cancer and its reversal by a nf-κb inhibitor
-
Nishio H, Yaguchi T, Sugiyama J et al (2014) Immunosuppression through constitutively activatedNF-κB signaling in human ovarian cancer and its reversal by a NF-κB inhibitor. Br J Cancer 110:2965–2974
-
(2014)
Br J Cancer
, vol.110
, pp. 2965-2974
-
-
Nishio, H.1
Yaguchi, T.2
Sugiyama, J.3
-
20
-
-
78349285473
-
Adjuvant effects of formalin-inactivated hsv through activation of dendritic cells and inactivation of myeloid-derived suppressor cells in cancer immunotherapy
-
Ohkusu-Tsukada K, Ohta S, Kawakami Y et al (2011) Adjuvant effects of formalin-inactivated HSV through activation of dendritic cells and inactivation of myeloid-derived suppressor cells in cancer immunotherapy. Int J Cancer 128:119–131
-
(2011)
Int J Cancer
, vol.128
, pp. 119-131
-
-
Ohkusu-Tsukada, K.1
Ohta, S.2
Kawakami, Y.3
-
21
-
-
73349142719
-
In situ cytotoxic and memory t cells predict outcome in patients with early-stage colorectal cancer
-
Pagès F, Kirilovsky A, Mlecnik B et al (2009) In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer. J Clin Oncol 27:5944–5951
-
(2009)
J Clin Oncol
, vol.27
, pp. 5944-5951
-
-
Pagès, F.1
Kirilovsky, A.2
Mlecnik, B.3
-
22
-
-
0029669950
-
A mutated b2-catenin gene encodes a melanoma –specific antigen recognized by tumor infiltrating lymphocytes
-
Robbins PF, El-Gamil M, Li YF et al (1996) A mutated b2-catenin gene encodes a melanoma –specific antigen recognized by tumor infiltrating lymphocytes. J Exp Med 183:1185–1192
-
(1996)
J Exp Med
, vol.183
, pp. 1185-1192
-
-
Robbins, P.F.1
El-Gamil, M.2
Li, Y.F.3
-
23
-
-
79952304769
-
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive withny-eso-1
-
Robbins PF, Morgan RA, Feldman SA et al (2011) Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive withNY-ESO-1. J Clin Oncol 29:917–924
-
(2011)
J Clin Oncol
, vol.29
, pp. 917-924
-
-
Robbins, P.F.1
Morgan, R.A.2
Feldman, S.A.3
-
24
-
-
84880276438
-
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive t cells
-
Robbins PF, Lu YC, El-Gamil M et al (2013) Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nat Med 19:747–752
-
(2013)
Nat Med
, vol.19
, pp. 747-752
-
-
Robbins, P.F.1
Lu, Y.C.2
El-Gamil, M.3
-
25
-
-
0031890206
-
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
-
Rosenberg SA, Yang J, Schwartzentruber D et al (1998) Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat Med 4:321–327
-
(1998)
Nat Med
, vol.4
, pp. 321-327
-
-
Rosenberg, S.A.1
Yang, J.2
Schwartzentruber, D.3
-
26
-
-
79960299888
-
Durable complete responses in heavily pretreated patients with metastatic melanoma using t-cell transfer immunotherapy
-
Rosenberg SA, Yang JC, Sherry RM et al (2011) Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res 17:4550–4557
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4550-4557
-
-
Rosenberg, S.A.1
Yang, J.C.2
Sherry, R.M.3
-
27
-
-
0028871599
-
Recognition of multiple epitopes in the human melanoma antigen gp100 by antigen specific peripheral blood lymphocytes stimulated with synthetic peptides
-
Salgaller M, Marincola F, Rivoltini L et al (1995) Recognition of multiple epitopes in the human melanoma antigen gp100 by antigen specific peripheral blood lymphocytes stimulated with synthetic peptides. Cancer Res 55:4972–4979
-
(1995)
Cancer Res
, vol.55
, pp. 4972-4979
-
-
Salgaller, M.1
Marincola, F.2
Rivoltini, L.3
-
28
-
-
79953151458
-
Cancer immunoediting: Integrating immunity’s roles in cancer suppression and promotion
-
Schreiber RD et al (2011) Cancer immunoediting: integrating immunity’s roles in cancer suppression and promotion. Science 331:1565–1570
-
(2011)
Science
, vol.331
, pp. 1565-1570
-
-
Schreiber, R.D.1
-
29
-
-
33745859743
-
The braf-mapk signaling pathway is essential for cancer immune evasion in human melanoma cells
-
Sumimoto H, Imabayashi F, Iwata T et al (2006) The BRAF-MAPK signaling pathway is essential for cancer immune evasion in human melanoma cells. J Exp Med 203:1651–1656
-
(2006)
J Exp Med
, vol.203
, pp. 1651-1656
-
-
Sumimoto, H.1
Imabayashi, F.2
Iwata, T.3
-
30
-
-
84859128199
-
Colocalization of inflammatory response withb7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
-
Taube JM, Anders RA, Young GD et al (2014) Colocalization of inflammatory response withB7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci Transl Med 4:127
-
(2014)
Sci Transl Med
, vol.4
, pp. 127
-
-
Taube, J.M.1
Ers, R.A.2
Young, G.D.3
-
31
-
-
0036215782
-
Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional hsv
-
Toda M, Iizuka Y, Kawase T et al (2002) Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional HSV. Cancer Gene Ther 9:356–364
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 356-364
-
-
Toda, M.1
Iizuka, Y.2
Kawase, T.3
-
32
-
-
84862859820
-
Safety, activity, and immune correlates of anti-pd-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR et al (2013) Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 366:2443–2454
-
(2013)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
33
-
-
33846213509
-
Enhancement of immunologic tumor regression by intratumoral administration of dendritic cells in combination with cryoablative tumor pretreatment and bacillus calmette-guerin cell wall skeleton stimulation
-
Udagawa M, Kudo-Saito C, Hasegawa G et al (2006) Enhancement of immunologic tumor regression by intratumoral administration of dendritic cells in combination with cryoablative tumor pretreatment and Bacillus Calmette-Guerin cell wall skeleton stimulation. Clin Cancer Res 12:7465–7475
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7465-7475
-
-
Udagawa, M.1
Kudo-Saito, C.2
Hasegawa, G.3
-
34
-
-
1442357201
-
Identification of a human glioma antigen, sox6, recognized by patients’ sera
-
Ueda R, Iizuka Y, Yoshida K, Kawase T, Kawakami Y, Toda M (2004) Identification of a human glioma antigen, SOX6, recognized by patients’ sera. Oncogene 23:1420–1427
-
(2004)
Oncogene
, vol.23
, pp. 1420-1427
-
-
Ueda, R.1
Iizuka, Y.2
Yoshida, K.3
Kawase, T.4
Kawakami, Y.5
Toda, M.6
-
35
-
-
74049105516
-
Identification of hla-a2- and a24-restrictedt-cell epitopes derived from sox6 expressed in glioma stem cells for immunotherapy
-
Ueda R, Ohkusu-Tsukada K, Fusaki N et al (2010) Identification of HLA-A2- and A24-restrictedT-cell epitopes derived from SOX6 expressed in glioma stem cells for immunotherapy. Int J Cancer 126:919–929
-
(2010)
Int J Cancer
, vol.126
, pp. 919-929
-
-
Ueda, R.1
Ohkusu-Tsukada, K.2
Fusaki, N.3
-
36
-
-
80051625929
-
Dissecting therapeutic resistance to raf inhibition in melanoma by tumor genomic profiling
-
Wagle N, Emery C, Berger MF et al (2011) Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. J Clin Oncol 29:3085–3096
-
(2011)
J Clin Oncol
, vol.29
, pp. 3085-3096
-
-
Wagle, N.1
Emery, C.2
Berger, M.F.3
-
37
-
-
84863393623
-
Selective braf inhibitors induce marked t-cell infiltration into human metastatic melanoma
-
Wilmott JS, Long GV, Howle JR et al (2012) Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma. Clin Cancer Res 18:1386–1394
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1386-1394
-
-
Wilmott, J.S.1
Long, G.V.2
Howle, J.R.3
-
38
-
-
79955829822
-
The mechanisms of cancer immune escape and development of overcoming strategies
-
Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Ueda R, Iwata-Kajihara T, Nishio H, Kawamura N, Kawakami Y et al (2011) The mechanisms of cancer immune escape and development of overcoming strategies. Int J Hematol 93:294
-
(2011)
Int J Hematol
, vol.93
, pp. 294
-
-
Yaguchi, T.1
Sumimoto, H.2
Kudo-Saito, C.3
Tsukamoto, N.4
Ueda, R.5
Iwata-Kajihara, T.6
Nishio, H.7
Kawamura, N.8
Kawakami, Y.9
-
39
-
-
84865428430
-
Immune suppression and resistance mediated by constitutive activation of wnt/β-catenin signaling in human melanoma cells
-
Yaguchi T, Goto Y, Kido K, Mochimaru H et al (2012) Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells. J Immunol 189:2110–2117
-
(2012)
J Immunol
, vol.189
, pp. 2110-2117
-
-
Yaguchi, T.1
Goto, Y.2
Kido, K.3
Mochimaru, H.4
|