Pressure ulcers in the hospitalized neonate: Rates and risk factors

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Visscher, Marty ^a,b   Taylor, Teresa ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN; INCIDENCE; INFANT; LENGTH OF STAY; NEWBORN; PREMATURITY; PRESSURE ULCER; PROSPECTIVE STUDY; RISK FACTOR;

HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; INFANT, PREMATURE; LENGTH OF STAY; PRESSURE ULCER; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84943361940     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep07429     Document Type: Article

References (53)

1. Schindler, C. A., Mikhailov, T. A., Fischer, K., Lukasiewicz, G., Kuhn, E. M. et al. Skin integrity in critically ill and injured children. Am J Crit Care 16, 568-574 (2007).
2. Eichenfield, L. F. & Hardaway, C. A. Neonatal dermatology. Curr Opin Pediatr 11, 471-474 (1999).
3. Evans, N. J. & Rutter, N. Development of the epidermis in the newborn. Biol Neonate 49, 74-80 (1986).
4. Cartlidge, P. The epidermal barrier. Semin Neonatol 5, 273-280 (2000).
5. Harpin, V. A. & Rutter, N. Barrier properties of the newborn infant's skin. J Pediatr 102, 419-425. (1983).
6. Okah, F. A., Wickett, R. R., Pickens, W. L. & Hoath, S. B. Surface electrical capacitance as a noninvasive bedside measure of epidermal barrier maturation in the newborn infant. Pediatrics 96, 688-692 (1995).
7. Agren, J., Sjors, G. & Sedin, G. Ambient humidity influences the rate of skin barrier maturation in extremely preterm infants. J Pediatr 148, 613-617 (2006).
8. Agren, J., Sjors, G. & Sedin, G. Transepidermal water loss in infants born at 24 and 25 weeks of gestation. Acta Paediatr 87, 1185-1190 (1998).
9. Nonato, L. B., Lund, C. H., Kalia, Y. N. & Guy, R. H. Transepidermal water loss in 24 and 25 weeks gestational age infants. Acta Paediatr 89, 747-748. (2000).
10. Kalia, Y. N., Nonato, L. B., Lund, C. H. & Guy, R. H. Development of skin barrier function in premature infants. J Invest Dermatol 111, 320-326. (1998).
11. Visscher, M., Odio, M., Taylor, T., White, T., Sargent, S. et al. Skin care in the NICU patient: effects of wipes versus cloth and water on stratum corneum integrity. Neonatology 96, 226-234 (2009).
12. Bouten, C. V., Oomens, C. W., Baaijens, F. P. & Bader, D. L. The etiology of pressure ulcers: skin deep or muscle bound? Arch Phys Med Rehabil 84, 616-619 (2003).
13. Stekelenburg, A., Strijkers, G. J., Parusel, H., Bader, D. L., Nicolay, K. et al. Role of ischemia and deformation in the onset of compression-induced deep tissue injury: MRI-based studies in a rat model. J Appl Physiol 102, 2002-2011 (2007).
14. Black, J., Baharestani, M., Cuddigan, J., Dorner, B., Edsberg, L. et al. National Pressure Ulcer Advisory Panel's updated pressure ulcer staging system. Urol Nurs 27, 144-150, 156 (2007).
15. Nijs, N., Toppets, A., Defloor, T., Bernaerts, K., Milisen, K. et al. Incidence and risk factors for pressure ulcers in the intensive care unit. J Clin Nurs 18, 1258-1266 (2009).
16. Keller, B. P., Wille, J., van Ramshorst, B. & van der Werken, C. Pressure ulcers in intensive care patients: a review of risks and prevention. Intensive Care Med 28, 1379-1388 (2002).
17. Sayar, S., Turgut, S., Dogan, H., Ekici, A., Yurtsever, S. et al. Incidence of pressure ulcers in intensive care unit patients at risk according to the Waterlow scale and factors influencing the development of pressure ulcers. J Clin Nurs 18, 765-774 (2009).
18. McLane, K. M., Bookout, K., McCord, S., McCain, J. & Jefferson, L. S. The 2003 national pediatric pressure ulcer and skin breakdown prevalence survey: a multisite study. J Wound Ostomy Continence Nurs 31, 168-178 (2004).
19. Black, J. M., Cuddigan, J. E., Walko, M. A., Didier, L. A., Lander, M. J. et al. Medical device related pressure ulcers in hospitalized patients. Int Wound J 7, 358-365 (2010).
20. Apold, J. & Rydrych, D. Preventing device-related pressure ulcers: using data to guide statewide change. J Nurs Care Qual 27, 28-34 (2012).
21. Willock, J., Hughes, J., Tickle, S., Rossiter, G., Johnson, C. et al. Pressure sores in children-the acute hospital perspective. J Tissue Viability 10, 59-62 (2000).
22. Curley, M. A., Quigley, S. M. & Lin, M. Pressure ulcers in pediatric intensive care: incidence and associated factors. Pediatr Crit Care Med 4, 284-290 (2003).
23. Curley, M. A., Razmus, I. S., Roberts, K. E. & Wypij, D. Predicting pressure ulcer risk in pediatric patients: the Braden Q Scale. Nurs Res 52, 22-33 (2003).
24. Kottner, J., Wilborn, D. & Dassen, T. Frequency of pressure ulcers in the paediatric population: a literature review and new empirical data. Int J Nurs Stud 47, 1330-1340 (2010).
25. Zollo, M. B., Gostisha, M. L., Berens, R. J., Schmidt, J. E. & Weigle, C. G. Altered skin integrity in children admitted to a pediatric intensive care unit. J Nurs Care Qual 11, 62-67 (1996).
26. Noonan, C., Quigley, S. & Curley, M. A. Skin integrity in hospitalized infants and children: a prevalence survey. J Pediatr Nurs 21, 445-453 (2006)
27. Groeneveld, A., Anderson, M., Allen, S., Bressmer, S., Golberg, M. et al. The prevalence of pressure ulcers in a tertiary care pediatric and adult hospital. J Wound Ostomy Continence Nurs 31, 108-120; quiz 121-102 (2004).
28. Nikolovski, J., Stamatas, G. N., Kollias, N. & Wiegand, B. C. Barrier function and water-holding and transport properties of infant stratum corneum are different from adult and continue to develop through the first year of life. J Invest Dermatol 128, 1728-1736 (2008).
29. Visscher, M. O., Chatterjee, R., Ebel, J. P., La Ruffa, A. A. & Hoath, S. B. Biomedical assessment and instrumental evaluation of healthy infant skin. Pediatr Dermatol 19, 473-481 (2002).
30. Visscher, M. O., Chatterjee, R., Munson, K. A., Pickens, W. L. & Hoath, S. B. Changes in diapered and nondiapered infant skin over the first month of life. Pediatr Dermatol 17, 45-51 (2000).
31. Waterlow, J. A. Pressure sore risk assessment in children. Paediatr Nurs 9, 21-24 (1997).
32. Boesch, R. P., Myers, C., Garrett, T., Nie, A., Thomas, N. et al. Prevention of Tracheostomy-related Pressure Ulcers in Children. Pediatrics 129, e792-797 (2012).
33. Berlowitz, D., Lukas, C. V., Parker, V., Niederhauser, A., Silver, J. et. al. Preventing Pressure Ulcer in Hospitals: A Toolkit for Improving Quality of Care. Vol. April 2011 Agency for Healthcare Research and Quality, Rockville, MD, http://www.ahrq.gov/professionals/systems/long-term-care/resources/pressure-ulcers/pressureulcertoolkit/index.html. Accessed: 04/28/2011.
34. Martin, L. A., Nelson, E. C., Lloyd, R. C. & Nolan, T. W. Whole System Measures. IHI Innovation Series white paper. Cambridge, Massachusetts: Institute for Healthcare Improvement; 2007. (Available on www.IHI.org).
35. Baharestani, M. M. & Ratliff, C. R. Pressure ulcers in neonates and children: an NPUAP white paper. Adv Skin Wound Care 20, 208, 210, 212, 214, 216, 218-220 (2007).
36. Fujii, K., Sugama, J., Okuwa, M., Sanada, H. & Mizokami, Y. Incidence and risk factors of pressure ulcers in seven neonatal intensive care units in Japan: a multisite prospective cohort study. Int Wound J 7, 323-328 (2010).
37. Willock, J., Harris, C., Harrison, J. & Poole, C. Identifying the characteristics of children with pressure ulcers. Nursing Times 101, 40 (2005).
38. Yong, S. C., Chen, S. J. & Boo, N. Y. Incidence of nasal trauma associated with nasal prong versus nasal mask during continuous positive airway pressure treatment in very low birthweight infants: a randomised control study. Arch Dis Child Fetal Neonatal Ed 90, F480-483 (2005).
39. Fischer, C., Bertelle, V., Hohlfeld, J., Forcada-Guex, M., Stadelmann-Diaw, C. et al. Nasal trauma due to continuous positive airway pressure in neonates. Arch Dis Child Fetal Neonatal Ed 95, F447-451 (2010).
40. Visscher, M., de Castro, M. V., Combs, L., Perkins, L., Winer, J. et al. Effect of chlorhexidine gluconate on the skin integrity at PICC line sites. J Perinatol 29, 802-807 (2009).
41. Visscher, M. O. Update on the use of topical agents in neonates. Newborn and Infant Nursing Reviews 9, 31-47 (2009).
42. Visscher, M. O., Utturkar, R., Pickens, W. L., La Ruffa, A. A., Robinson, M. et al. Neonatal skin maturation-vernix caseosa and free amino acids. Pediatr Dermatol 28, 122-132 (2011).
43. Bates-Jensen, B. M., McCreath, H. E. & Pongquan, V. Subepidermal moisture is associated with early pressure ulcer damage in nursing home residents with dark skin tones: pilot findings. JWound Ostomy Continence Nurs 36, 277-284 (2009).
44. Cornelissen, L. H., Bronneberg, D., Bader, D. L., Baaijens, F. P. & Oomens, C. W. The transport profile of cytokines in epidermal equivalents subjected to mechanical loading. Ann Biomed Eng 37, 1007-1018 (2009).
45. Jiang, L. P., Tu, Q., Wang, Y. & Zhang, E. Ischemia-reperfusion injury-induced histological changes affecting early stage pressure ulcer development in a rat model. Ostomy Wound Manage 57, 55-60 (2011).
46. Kligman. Hydration Injury to Human Skin. in The Irritant Contant Dermatitis Syndrome (ed. van der Valk P, M.H.) 187-194 (CRC Press, Boca Ritan, 1996).
47. Lee, J. Y., Effendy, I. & Maibach, H. I. Acute irritant contact dermatitis: recovery time in man. Contact Dermatitis 36, 285-290 (1997).
48. Ramsing, D. W. & Agner, T. Effect of water on experimentally irritated human skin. Br J Dermatol 136, 364-367 (1997).
49. Sivamani, R. K., Goodman, J., Gitis, N. V. & Maibach, H. I. Friction coefficient of skin in real-time. Skin Res Technol 9, 235-239 (2003).
50. Zimmerer, R. E., Lawson, K. D. & Calvert, C. J. The effects of wearing diapers on skin. Pediatr Dermatol 3, 95-101 (1986).
51. O'Sullivan, K. L., Engrav, L. H., Maier, R. V., Pilcher, S. L., Isik, F. F. et al. Pressure sores in the acute trauma patient: incidence and causes. J Trauma 42, 276-278 (1997).
52. Pinchcofsky-Devin, G.D. & Kaminski, M. V., Jr. Correlation of pressure sores and nutritional status. J Am Geriatr Soc 34, 435-440 (1986).
53. Linares, H. A., Mawson, A. R., Suarez, E. & Biundo, J. J. Association between pressure sores and immobilization in the immediate post-injury period. Orthopedics 10, 571-573 (1987).