Fish oil provides protection against the oxidative stress in pilocarpine model of epilepsy

Metabolic Brain Disease

Volumn 30, Issue 4, 2015, Pages 903-909

  Nejm, Mariana B ^a   Haidar, André A ^a   Marques, Márcia J G ^a   Hirata, Aparecida E ^a   Nogueira, Fernando N ^b   Cavalheiro, Esper A ^a   Scorza, Fulvio A ^a   Cysneiros, Roberta Monterazzo ^c  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c MACKENZIE PRESBYTERIAN UNIVERSITY   (Brazil)

Author keywords

Epilepsy; Fish oil; Oxidative stress; Pilocarpine

Indexed keywords

CATALASE; FISH OIL; PILOCARPINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE; SUPEROXIDE DISMUTASE; NEUROPROTECTIVE AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; TEMPORAL LOBE EPILEPSY; TREATMENT RESPONSE; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; EPILEPSY; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ANIMALS; DISEASE MODELS, ANIMAL; EPILEPSY; FISH OILS; MALE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PILOCARPINE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES;

EID: 84943361134     PISSN: 08857490     EISSN: 15737365     Source Type: Journal    
DOI: 10.1007/s11011-015-9666-0     Document Type: Article

References (29)

1. Aebi H (1984) Catalase in vitro. Methods Enzymol 105: 121-126. doi: 10. 1016/S0076-6879(84)05016-3.
2. Babior BM (2004) NADPH oxidase. Curr Opin Immunol 16: 42-47. doi: 10. 1016/j. coi. 2003. 12. 001.
3. Bellissimo MI, Amado D, Abdalla DS, Ferreira EC, Cavalheiro EA, Naffah-MazzacorattiMG (2001) Superoxide dismutase, glutathione peroxidase activities and the hydroperoxide concentration are modified in the hippocampus of epileptic rats. Epilepsy Res 46: 121-128. doi: 10. 1016/S0920-1211(01)00269-8.
4. Bondy SC, Lee DK (1993) Oxidative stress induced by glutamate receptors agonists. Brain Res 610: 229-233. doi: 10. 1016/0006-8993(93) 91405-H.
5. Bonfoco E, Krainic D, Ankarcrona M, Nocotera P, Lipton AS (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-d-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci 92: 7162-7166.
6. Bradford MM (1976) A rapid and sensitive method for quantification of microgramquantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254. doi: 10. 1016/0003-2697(76) 90527-3.
7. Cavalheiro EA (1995) The pilocarpine model of epilepsy. Ital J Neurol Sci 16: 33-37.
8. Curia G, Longo D, Biagini G, Jones RS, AvoliM (2008) The pilocarpine model of temporal lobe epilepsy. J Neurosci Methods 172(2): 143-157. doi: 10. 1016/j. jneumeth. 2008. 04. 019.
9. Ferrari D, Cysneiros RM, Scorza CA, Arida RM, Cavalheiro EA, de Almeida ACG, Scorza FA (2008) Neuroprotective activity of omega-3 fatty acids against epilepsy-induced hippocampal damage: quantification with immunohistochoemical for calcium-binding proteins. Epilepsy Behav 13: 36-42. doi: 10. 1016/j. yebeh. 2008. 01. 001.
10. Fisher M, Levine PH, Weiner BH (1990) Dietary n-3 fatty acid supplementation reduces superoxide production and chemiluminescence in a monocyte-enriched preparation of leukocytes. Am J Clin Nutr 51: 804-808.
11. Freitas RM, Vasconcelos SM, Souza FC, Viana GS, FontelesMM (2005) Oxidative stress in the hippocampus after pilocarpine-induced status epilepticus in Wistar rats. FEBS J 272: 1307-1312. doi: 10. 1111/j. 1742-4658. 2004. 04537. x.
12. Fujikawa DG (2005) Prolonged seizures and cellular injury: understanding the connection. Epilepsy Behav 7(3): S3-S11. doi: 10. 1016/j. yebeh. 2005. 08. 003.
13. HossainMS, HashimotoM, Gamoh S, Masumura S (1999)Antioxidative effects of docosahexaenoic acid in the cerebrum versus cerebellum and brainstem of aged hypercholesterolemic rats. J Neurochem 72(3): 1133-1138. doi: 10. 1046/j. 1471-4159. 1999. 0721133. x.
14. Inni SM (2007) Dietary (n-3) fatty acids and brain development. J Nutr 137(4): 855-859. doi: 10. 1016/j. brainres. 2008. 08. 078.
15. Liu SH, Chang CD, Chen PH, Su JR, Chen CC, Chaung HC (2012) Docosahexaenoic acid and phosphatidylserine supplementations improve antioxidant activities and cognitive functions of the developing brain on pentylenetetrazol-induced seizure model. Brain Res 1451: 19-26. doi: 10. 1016/j. brainres. 2012. 02. 060.
16. McCann JC, Ames BN (2005) Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals. Am J Clin Nutr 82(2): 281-295.
17. Nevander G, Ingvar M, Auer R, Siesjö BK (1985) Status epilepticus in well-oxygenated rats causes neuronal necrosis. Ann Neurol 18(3): 281-290. doi: 10. 1002/ana. 410180303.
18. Patel M, Li QY, Chang LY, Crapo J, Liang LP (2005) Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage. J Neurochem 92: 123-131. doi: 10. 1111/j. 1471-4159. 2004. 02838. x.
19. Paxinos JP, Watson C (1998) The rat brain in stereotaxic coordinates. Academic, San Diego.
20. Pestana RF, Kinjo ER, Hernandes MS, Britto LRG (2010) Reactive oxygen species generated by NAD(P)H oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy. Neurosci Lett 484: 187-191. doi: 10. 1016/j. neulet. 2010. 08. 049.
21. Rumià J, Marmol F, Sanchez J, Giménez-Crouseilles J, Carreño M, Bargalló N, Boget T, Pintor L, Setoain X, Donaire A, Saez GT, Ribalta T, Ferrer E, Puig-Parellada P (2013) Oxidative stress markers submitted to epilepsy surgery. Epilepsy Res 107(1-2): 75-81. doi: 10. 1016/j. eplepsyres. 2013. 08. 020.
22. Schlanger S, Shinitzky M, Yam D (2002) Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients. Epilepsia 43: 103-104. doi: 10. 1046/j. 1528-1157. 2002. 13601. x.
23. Shulz JN, Henshaw DR, Siwek D, Jenkins BG, Ferrante RJ, Cipolloni PB, Kowall NW, Rosen BR, Beal MF (1995) Involvement of free radicals in excitotoxicity in vivo. J Neurochem 64: 2239-2247. doi: 10. 1046/j. 1471-4159. 1995. 64052239. x.
24. TakahashiM, Tsuboyama-Kasaoka N, Nakatani T (2002) Fish oil feeding alters liver gene expressions to defend against PPAR alpha activation and ROS production. Am J Physiol Gastrointest Liver Physiol 282: G338-G348. doi: 10. 1152/ajpgi. 00376. 2001.
25. Turski WA, Cavalheiro EA, Bortolotto ZA, Mello LM, Schwarz M, Turski L (1984) Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysis. Brain Res 321(2): 237-253.
26. Valko M, Rhodes CJ, Izakovic MM (2006) Free radicals metals and antioxidants on oxidative stress-induced cancer. Chem Biol Interact 160: 1-40. doi: 10. 1016/j. cbi. 2005. 12. 009.
27. Vincent AM, Maiese K (1999) Nitric oxide induction of neuronal endonuclease activity in programmed cell death. Exp Cell Res 246: 290-300. doi: 10. 1006/excr. 1998. 4282.
28. Vincent P, Mulle C (2009) Kainate receptors in epilepsy and excitotoxicity. Neuroscience 158: 309-323. doi: 10. 1016/j. neuroscience. 2008. 02. 066.
29. Wu A, Ying Z, Gomez-Pinilla F (2004) Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats. J Neurotrauma 21(10): 1457-1467. doi: 10. 1089/neu. 2004. 21. 1457.