GATA3 expression in gestational trophoblastic tissues and tumours

Histopathology

Volumn 67, Issue 5, 2015, Pages 636-644

  Mirkovic, Jelena ^a,b   Elias, Kevin ^a,b   Drapkin, Ronny ^c,d   Barletta, Justine A ^a,b   Quade, Bradley ^a,b   Hirsch, Michelle S ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Choriocarcinoma; Endometrial adenocarcinoma; GATA3; Hydatidiform mole; Immunohistochemistry; Mullerian; Placenta; Trophoblast

Indexed keywords

TRANSCRIPTION FACTOR GATA 3; GATA3 PROTEIN, HUMAN; TUMOR MARKER;

ARTICLE; BREAST CARCINOMA; CERVICAL CANCER CELL LINE; CHORIOCARCINOMA; CONTROLLED STUDY; CYTOTROPHOBLAST; EMBRYO; ENDOMETRIAL CANCER CELL LINE; ENDOMETRIUM BIOPSY; ENDOMETRIUM CARCINOMA; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDATIDIFORM MOLE; IMMUNOHISTOCHEMISTRY; NIDATION; PLACENTA; PLACENTA TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNCYTIOTROPHOBLAST; T CELL LEUKEMIA; THIRD TRIMESTER PREGNANCY; TRANSITIONAL CELL CARCINOMA; TROPHOBLAST; TROPHOBLASTIC TUMOR; WESTERN BLOTTING; BIOSYNTHESIS; METABOLISM; PATHOLOGY; PREGNANCY;

BIOMARKERS, TUMOR; BLOTTING, WESTERN; FEMALE; GATA3 TRANSCRIPTION FACTOR; GESTATIONAL TROPHOBLASTIC DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; PREGNANCY; TROPHOBLASTS;

EID: 84943351117     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/his.12681     Document Type: Article

References (23)

1. Chou J, Provot S, Werb Z. GATA3 in development and cancer differentiation: cells GATA have it!. J. Cell. Physiol. 2010; 222; 42-49.
2. Saben J, Zhong Y, McKelvey S et al. A comprehensive analysis of the human placenta transcriptome. Placenta 2014; 35; 125-131.
3. Home P, Ray S, Dutta D et al. GATA3 is selectively expressed in the trophectoderm of peri-mplantation embryo and directly regulates Cdx2 gene expression. J. Biol. Chem. 2009; 284; 28729-28737.
4. Ralston A, Cox BJ, Nishioka N et al. Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2. Development 2010; 137; 395-403.
5. Ma GT, Roth ME, Groskopf JC et al. GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. Development 1997; 124; 907-914.
6. Liu H, Shi J, Wilkerson ML et al. Immunohistochemical evaluation of GATA3 expression in tumors and normal tissues: a useful immunomarker for breast and urothelial carcinomas. Am. J. Clin. Pathol. 2012; 138; 57-64.
7. Gonzalez RS, Wang J, Kraus T et al. GATA-3 expression in male and female breast cancers: comparison of clinicopathologic parameters and prognostic relevance. Hum. Pathol. 2013; 44; 1065-1070.
8. Cimino-Mathews A, Subhawong AP, Illei PB et al. GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas. Hum. Pathol. 2013; 44; 341-349.
9. Wendroth SM, Mentrikoski MJ, Wick MR. GATA3 expression in morphologic subtypes of breast carcinoma: a comparison with gross cystic disease fluid protein 15 and mammaglobin. Ann. Diagn. Pathol. 2015; 19; 6-9.
10. Chang A, Amin A, Gabrielson E et al. Utility of GATA3 immunohistochemistry in differentiating urothelial carcinoma from prostate adenocarcinoma and squamous cell carcinomas of the uterine cervix, anus, and lung. Am. J. Surg. Pathol. 2012; 36; 1472-1476.
11. Miettinen M, Mccue PA, Sarlomo-rikala M et al. GATA3: a multispecific but potentially useful marker in surgical pathology. Am. J. Surg. Pathol. 2014; 38; 13-22.
12. Howitt BE, Jimenez C, Barletta JA et al. GATA3 is a sensitive and specific marker of mesonephric differentiation and neoplasia in the lower Mullerian tract. Am. J. Surg. Pathol. 2015 (in press).
13. Banet N, Gown AM, IeM S et al. GATA-3 expression in trophoblastic tissues: an immunohistochemical study of 445 cases, including diagnostic utility. Am. J. Surg. Pathol. 2015; 39; 101-108.
14. Pelkey TJ, Frierson HF Jr, Mills SE et al. Detection of the alpha-subunit of inhibin in trophoblastic neoplasia. Hum. Pathol. 1999; 30; 26-31.
15. Shih IM, Seidman JD, Kurman RJ. Placental site nodule and characterization of distinctive types of intermediate trophoblast. Hum. Pathol. 1999; 30; 687-694.
16. Horn LC, Bilek K. Histologic classification and staging of gestational trophoblastic disease. Gen. Diagn. Pathol. 1997; 143; 87-101.
17. Li J, Shi Y, Wan X et al. Epithelioid trophoblastic tumor: a clinicopathological and immunohistochemical study of seven cases. Med. Oncol. 2011; 28; 294-299.
18. Shih IM, Kurman RJ. p63 expression is useful in the distinction of epithelioid trophoblastic and placental site trophoblastic tumors by profiling trophoblastic subpopulations. Am. J. Surg. Pathol. 2004; 28; 1177-1183.
19. Lee Y, Kim KR, McKeon F et al. A unifying concept of trophoblastic differentiation and malignancy defined by biomarker expression. Hum. Pathol. 2007; 38; 1003-1013.
20. Banet N, DeScipio C, Murphy KM et al. Characteristics of hydatidiform moles: analysis of a prospective series with p57 immunohistochemistry and molecular genotyping. Mod. Pathol. 2014; 27; 238-254.
21. Laury AR, Perets R, Piao H et al. A comprehensive analysis of PAX8 expression in human epithelial tumors. Am. J. Surg. Pathol. 2011; 35; 816-826.
22. Esheba GE, Longacre TA, Atkins KA et al. Expression of the urothelial differentiation markers GATA3 and placental S100 (S100P) in female genital tract transitional cell proliferations. Am. J. Surg. Pathol. 2009; 33; 347-353.
23. Nonaka D, Wang BY, Edmondson D et al. A study of Gata3 and Phox2b expression in tumors of the autonomic nervous system. Am. J. Surg. Pathol. 2013; 37; 1236-1241.