Detection of the alpha-subunit of inhibin in trophoblastic neoplasia

Human Pathology

Volumn 30, Issue 1, 1999, Pages 26-31

  Pelkey, Timothy J ^a   Frierson Jr , Henry F ^a   Mills, Stagey E ^a   Stoler, Mark H ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Choriocarcinoma; Inhibin; Placental site trophoblastic tumor; Trophoblastic neoplasia

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; INHIBIN; PLACENTA LACTOGEN;

ARTICLE; CHORIOCARCINOMA; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HYDATIDIFORM MOLE; IMMUNOHISTOCHEMISTRY; PLACENTA; PROTEIN DETERMINATION; TROPHOBLASTIC DISEASE;

EID: 0032903086     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(99)90296-4     Document Type: Article

References (71)

1. Vale W, Rivier C, Hsueh A, et al: Chemical and biological characterization of the inhibin family of protein hormones. Recent Prog Horm Res 44:1-35, 1989
2. Vale WV, Hsueh A, Rivier C, et al: The inhibin/activin family of hormones and growth factors, in Sporn MA, Roberts AB (eds): Peptide Growth Factors and Their Receptors: Handbook of Experimental Physiology (vol 95). Berlin, Springer-Verlag, 1990, pp 211-245
3. Burger HG: Clinical utility of inhibin measurements. J Clin Endocrinol Metab 76:1391-1396, 1993
4. Burger HG: Inhibin. Reprod Med Rev 1:1-20, 1992
5. Petraglia F, Ancheschi MM, Calza L, et al: Inhibin and activin in human fetal membranes: Evidence for a local effect on prostaglandin release. J Clin Endocrinol Metab 77:542-548, 1993
6. Petraglia F, Garuti GC, Calza L, et al: Inhibin subunits in human placenta: Localization and messenger ribonucleic acid levels during pregnancy. Am J Obstet Gynecol 165:750-758, 1991
7. Petraglia F, Calza L, Garuti GC, et al: Presence and synthesis of inhibin subunits in human decidua. J Clin Endocrinol Metab 71:487-492, 1990
8. Petraglia F, Vaughan J, Vale W: Inhibin and activin modulate release of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone from cultured human placental cells. Proc Natl Acad Sci U S A 86:5114-5117, 1989
9. Qu J, Thomas K: Inhibin and activin production in human placenta. Endocr Rev 16:485-507, 1995
10. Minami S, Yamoto M, Nakano R: Immunohistochemical localization of inhibin-activin subunits in hydatidiform mole and invasive mole. Obstet Gynecol 82:414-418, 1993
11. Wada M, Shintani Y, Kosaka M, et al: Immunohistochemical localization of activin A and follistatin in human tissues. Endocr J 43:375-385, 1996
12. Mayo KE, Cerelli GM, Spiess J, et al: Inhibin A-subunit cDNAs from porcine ovary and human placenta. Proc Nad Acad Sci U S A 83:5849-5853, 1986
13. Pelkey TJ, Frierson HF Jr, Mills SE, et al: The alpha-subunit of inhibin in adrenal cortical neoplasia. Mod Pathol 11:516-524, 1998
14. Pelkey TJ, Frierson HF Jr, Mills SE, et al: The diagnostic utility of inhibin staining in ovarian neoplasia. Int J Gynecol Pathol 17:97-105, 1998
15. Demura R, Kubo O, Suzuki T, et al: Demonstration of activin in normal pituitary and in various human pituitary adenomas by immunohistochemistry. Endocr J 43:429-432, 1996
16. McLachlan RI, Robertson DM, Healy DL, et al: Circulating immunoreactive inhibin levels during the normal human menstrual cycle. J Clin Endocrinol Metab 65:954-961, 1987
17. Yohkaichiya T, Fukaya T, Hoshiai H, et al: Inhibin: A new circulating marker of hydatidiform mole. Br Med J 298:1684-1685, 1989
18. Ordonez NG, Luna MA: Choriocarcinoma of the colon. Am J Gastroenterol 79:39-42, 1984
19. Heaton GE, Matthews TH, Christopherson WM: Malignant trophoblastic tumors with massive hemorrhage presenting as liver primary: A report of two cases. Am J Surg Pathol 10:342-347, 1986
20. Horn LC, Goretzlehner U, Dirnhofer S: Placental site trophoblastic tumor (PSTT) initially misdiagnosed as cervical carcinoma. Pathol Res Pract 193:225-230, 1997
21. Ayhan A, Tuncer ZS, Tanir M, et al: Central nervous system involvement in gestational trophoblastic neoplasia. Acta Obstet Gynecol Scand 75:548-550, 1996
22. Kim SN, ChiJG, Kim YW, et al: Neonatal choriocarcinoma of liver. Pediatr Pathol 13:723-730, 1993
23. Fernandez Alonso J, Saez C, Perez P, et al: Primary pure choriocarcinoma of the liver. Pathol Res Pract 188:375-377, 1992
24. Childs CC, Korsten MA, Choi HS, et al: Pancreatic choriocarcinoma presenting as inflammatory pseudocyst. Gastroenterology 89:426-431, 1985
25. Imai Y, Kawabe T, Takahashi M, et al: A case of primary gastric choriocarcinoma and a review of the Japanese literature. J Gastroenterol 29:642-646, 1994
26. Yokoyama S, Hayashida Y, Nagahama J, et al: Primary and metaplastic choriocarcinoma of the bladder: A report of two cases. Acta Cytol 36:176-182, 1992
27. Sullivan LG: Primary choriocarcinoma of the lung in a man. Arch Pathol Lab Med 113:82-83, 1989
28. Cosnow I, Fretzin DF: Choriocarcinoma metastatic to skin. Arch Dermatol 109:551-553, 1974
29. Mazur MT: Metastatic gestational choriocarcinoma. Unusual pathologic variant following therapy. Cancer 63:1370-1377, 1989
30. Ulbright TM, Young RH, Scully RE: Trophoblastic tumors of the testis other than classic choriocarcinoma: "Monophasic" choriocarcinoma and placental site trophoblastic tumor: A report of two cases. Am J Surg Pathol 21:282-288, 1997
31. Kurman RJ: The morphology, biology, and pathology of intermediate trophoblast: A look back to the present. HUM PATHOL 22:847-855, 1991
32. Minami S, Yammoto M, Nakano R: Immunohistochemical localization of inhibin/activin subunits in human placenta. Obstet Gynecol 80:410-414, 1992
33. Minami S, Yamoto M, Nakano R: Immunohistochemical localization of inhibin-activin subunits in hydatidiform mole and invasive mole. Obstet Gynecol 82:414-418, 1993
34. Merchenthaler I, Culler MD, Petrusz P, et al: Immunocytochemical localization of inhibin in rat and human reproductive tissues. Mol Cell Endocrinol 54:239-243, 1987
35. Heitz PU, von Herbay G, Klöppel G, et al: The expression of subunits of human chorionic gonadotropin (hCG) by nontrophoblastic, nonendocrine, and endocrine tumors. Am J Clin Pathol 88:467-472, 1987
36. Nakanuma Y, Unoura M, Noto H, et al: Human chorionic gonadotropin in primary liver carcinoma in adults. Virchows Arch 409:365-373, 1986
37. Meredith RF, Wagman LD, Piper JA, et al: Beta-chain human chorionic gonadotropin-producing leiomyosarcoma of the small intestine. Cancer 58:131-135, 1986
38. Shah VM, Newman J, Crocker J, et al: Ectopic beta-human chorionic gonadotropin production by bladder urothelial neoplasia. Arch Pathol Lab Med 110:107-111, 1986
39. Mohabeer J, Buckley CH, Fox H: An immunohistochemical study of the incidence and significance of human chorionic gonadotropin synthesis by epithelial ovarian neoplasms. Gynecol Oncol 16:78-84, 1983
40. Buckley CH, Fox H: An immunohistochemical study of the significance of hCG secretion by large bowel adenocarcinomata. J Clin Pathol 32:368-372, 1979
41. Tormey DC, Waalkes TP, Simon RM: Biological markers in breast carcinoma: Clinical correlations with human chorionic gonadotrophin. Cancer 39:2391-2396, 1977
42. Boucher LD, Yoneda K: The expression of trophoblastic cell markers by lung carcinomas. HUM PATHOL 26:1201-1206, 1995
43. Heyderman E, Chapman DV, Richardson TC, et al: Human chorionic gonadotropin and human placental lactogen in extragonadal tumors: An immunoperoxidase study of ten non-germ cell neoplasms. Cancer 56:2674-2682, 1985
44. Home CHW, Reid IN, Milne GD: Prognostic significance of inappropriate production of pregnancy proteins by breast cancers. Lancet 2:279-282, 1976
45. Kurman RJ, Young RH, Norris HJ, et al: Immunocytochemical localization of placental lactogen and chorionic gonadotropin in the normal placenta and trophoblastic tumors, with emphasis on intermediate trophoblast and the placental site trophoblastic tumor. IntJ Gynecol Pathol 3:101-121, 1984
46. Niehans GA, Manivel JC, Copland GT, et al: Immunohistochemistry of germ cell and trophoblastic neoplasms. Cancer 62:1113-1123, 1988
47. Motoyama T, Ohta T, Ajioka Y, et al: Neoplastic and nonneoplastic intermediate trophoblasts: An immunohistochemical and ultrastructural study. Pathol Int 44:57-65, 1994
48. Fukunaga M, Ushigome S: Malignant trophoblastic tumors: Immunohistochemical and flow cytometric comparison of choriocarcinoma and placental site trophoblastic tumors. HUM PATHOL 24:1098-1106, 1993
49. Berger G, Verbaere J, Feroldi J: Placental site trophoblastic tumor of the uterus: An ultrastructural and immunohistochemical study. Ultrastruct Pathol 6:319-329, 1984
50. Gloor E, Hürlimann J: Trophoblastic pseudotumor of the uterus: Clinicopathologic report with immunohistochemical and ultrastructural studies. Am J Surg Pathol 5:5-13, 1981
51. Horne CHW, Rankin R, Bremner RD: Pregnancy-specific proteins as markers for gestational trophoblastic disease. IntJ Gynecol Pathol 3:27-40, 1987
52. Hager H, Gliemann J, Hamilton-Dutoit S, et al: Developmental regulation of tissue transglutaminase during human placentation and expression in neoplastic trophoblast. J Pathol 181:106-110, 1997
53. Deftos LJ, Burton DW, Brandt DW, et al: Neoplastic hormone-producing cells of the placenta produce and secrete parathyroid hormone-related protein. Lab Invest 71:847-852, 1994
54. Leivo I, Laurila P, Wahlstrom T, et al: Expression of merosin, a tissue-specific basement membrane protein, in the intermediate trophoblast cells of choriocarcinoma and placenta. Lab Invest 60:783-790, 1989
55. Wells M, Bulmer JN: The human placental bed: Histology, immunohistochemistry and pathology. Histopathology 13:483-498, 1988
56. King A, Loke YW: Differential expression of blood group-related carbohydrate antigens by trophoblast populations. Placenta 9:513-521, 1988
57. Bulmer JN, Thrower S, Wells M: Expression of epidermal growth factor receptor and transferrin receptor by human trophoblast populations. Am J Reprod Immunol 21:87-93, 1989
58. Feinberg RF, Kao L-C, Haimonwitz JE: Plasminogen activator inhibitor types 1 and 2 in human trophoblasts: PAI-1 is an immunocytochemical marker of invading trophoblasts. Lab Invest 61:20-26, 1989
59. Garin-Chesa P, Campbell I, Saigo PE, et al: Trophoblast and ovarian cancer antigen LK26: Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein. Am J Pathol 142:557-567, 1993
60. Rettig WJ, Cordon-Carco C, Koulos JP, et al: Cell surface antigens of human trophoblast and choriocarcinoma defined by monoclonal antibodies. IntJ Cancer 35:469-475, 1985
61. Mwenda JM, Maher PM, Melling GC, et al: A murine monoclonal antibody (RV3-27) raised against isolated human placental endogenous retroviral particles and reactive with syncytiotrophoblast. J Reprod Immunol 26:75-95, 1994
62. Rhoton-Vlasak A, Wagner JM, RutgersJL, et al: Placental site trophoblastic tumor: Human placental lactogen and pregnancy-associated major basic protein as immunohistologic markers. HUM PATHOL 29:280-288, 1998
63. Shih IM, Kurman RJ: Expression of melanoma cell adhesion molecule in intermediate trophoblast. Lab Invest 75:377-388, 1996
64. Huettner PC, Gersell DJ: Placental site nodule: A clinicopathologic study of 38 cases. Int J Gynecol Pathol 13:191-198, 1994
65. Shih IM, Wang TL, Westra WH: Diagnostic and biological implications of Mel-CAM expression in mesenchymal neoplasms. Clin Cancer Res 2:569-575, 1996
66. O'Connor DM, Kurman RJ: Intermediate trophoblast in uterine curettings in the diagnosis of ectopic pregnancy. Obstet Gynecol 72:665-670, 1988
67. Khong TY, Stewart JCR, Mott C, et al: The usefulness of human placental lactogen and keratin immunohistochemistry in the assessment of tissue from purported intrauterine pregnancies. Am J Clin Pathol 102:72-75, 1994
68. Angel E, Davis JR, Nagel RB: Immunohistochemical demonstration of placental hormones in the diagnosis of uterine versus ectopic pregnancy. Am J Clin Pathol 84:705-709, 1985
69. Wan SK, Lam PWY, Pau MY, et al: Multiclefted nuclei: A helpful feature for identification of intermediate trophoblastic cells in uterine curetting specimens. Am J Surg Pathol 16:1226-1232, 1992
70. Gurusinghe CJ, Healy DL, Jobling T, et al: Inhibin and activin are demonstrable by immunohistochemistry in ovarian tumor tissue. Gynecol Oncol 57:27-32, 1995
71. Hussong J, Woodruff T, Keh PC: Immunohistochemical study of primary ovarian tumors with inhibin antibody. Mod Pathol 1:102A, 1997 (abstr 589)