Distinct expression patterns of AAV8 vectors with broadly active promoters from subretinal injections of neonatal mouse eyes at two different ages

Advances in Experimental Medicine and Biology

Volumn 854, Issue , 2016, Pages 501-507

  Xiong, Wenjun ^a   Cepko, Constance ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

AAV8; Cellular tropism; Chicken actin promoter enhancer intron; Human cytomegalovirus (CMV) immediate early (IE) enhancer promoter; Neonatal mouse eye; Subretinal injection; Transgene expression

Indexed keywords

GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; IMMEDIATE EARLY PROTEIN; PARVOVIRUS VECTOR; PROTEIN CAGGS; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS 8; AGE DISTRIBUTION; ANIMAL CELL; ANIMAL TISSUE; CELL LABELING; CYTOMEGALOVIRUS; EYE DEVELOPMENT; FEMALE; GLIA CELL; INTRON; MOLECULAR CLONING; MOUSE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PHOTORECEPTOR; PHOTORECEPTOR OUTER SEGMENT; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; RETINA; RETINA AMACRINE CELL; RETINA GANGLION CELL; RETINA HORIZONTAL NERVE CELL; RETINA INNER NUCLEAR LAYER; RETINA OUTER NUCLEAR LAYER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBRETINAL DRUG ADMINISTRATION; TRANSCRIPTION REGULATION; VIRION; VIRUS CAPSID; VIRUS GENOME; ADMINISTRATION AND DOSAGE; ANIMAL; DEPENDOPARVOVIRUS; GENE EXPRESSION PROFILING; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOHISTOCHEMISTRY; INJECTION; METABOLISM; PHOTORECEPTOR CELL; TIME FACTOR;

ANIMALS; ANIMALS, NEWBORN; DEPENDOVIRUS; GENE EXPRESSION PROFILING; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INJECTIONS; MICE; PHOTORECEPTOR CELLS, VERTEBRATE; PROMOTER REGIONS, GENETIC; RETINA; RETINAL GANGLION CELLS; TIME FACTORS; TRANSDUCTION, GENETIC;

EID: 84943303109     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-17121-0_67     Document Type: Chapter

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