A survey of attitudes and practices regarding the use of steroid supplementation in pediatric sepsis

Pediatric Emergency Care

Volumn 31, Issue 10, 2015, Pages 694-698

  Carmean, Amanda ^a,b   Fortenberry, James D ^c,d   McCracken, Courtney ^c   Hebbar, Kiran B ^c,d  

^a Children's Hospital Colorado   (United States)

^b Rocky Vista University   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

Author keywords

Adrenal insufficiency; Current practice; Sepsis; Steroid use in sepsis

Indexed keywords

CORTICOSTEROID; ANTIINFLAMMATORY AGENT; HYDROCORTISONE; STEROID; VASOCONSTRICTOR AGENT;

ARTICLE; CHILD; CHILDHOOD DISEASE; CLINICAL PRACTICE; CORTICOSTEROID THERAPY; CRITICAL ILLNESS; DIET SUPPLEMENTATION; DRUG USE; FEMALE; FOLLOW UP; HUMAN; HYPERGLYCEMIA; INTENSIVE CARE; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MYOPATHY; NEUROPATHY; OUTCOME ASSESSMENT; PATIENT ATTITUDE; PHYSICIAN ATTITUDE; PRACTICE GUIDELINE; SEPTIC SHOCK; SUPERINFECTION; TREATMENT CONTRAINDICATION; TREATMENT DURATION; TREATMENT RESPONSE; WOUND HEALING IMPAIRMENT; ADRENAL INSUFFICIENCY; ADULT; ENDOCRINOLOGY; HEALTH PERSONNEL ATTITUDE; MEDICAL EDUCATION; PEDIATRICS; PROCEDURES; QUESTIONNAIRE; SHOCK, SEPTIC; STANDARDS;

ADRENAL CORTEX HORMONES; ADRENAL INSUFFICIENCY; ADULT; ANTI-INFLAMMATORY AGENTS; ATTITUDE OF HEALTH PERSONNEL; CHILD; ENDOCRINOLOGY; FELLOWSHIPS AND SCHOLARSHIPS; HUMANS; HYDROCORTISONE; INTENSIVE CARE UNITS, PEDIATRIC; PEDIATRICS; PRACTICE GUIDELINES AS TOPIC; PRACTICE PATTERNS, PHYSICIANS'; SHOCK, SEPTIC; STEROIDS; SURVEYS AND QUESTIONNAIRES; VASOCONSTRICTOR AGENTS;

EID: 84943225147     PISSN: 07495161     EISSN: 15351815     Source Type: Journal    
DOI: 10.1097/PEC.0000000000000561     Document Type: Article

References (19)

1. Hall M. Children's Hospital Association database results-unpublished data: Children's Hospital Association 2013. Available at: www. childrenshospitals.org. Accessed February 1, 2012.
2. Brierley J, Carcillo JA, Choong K, et al. Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine. Crit Care Med. 2009;37:666-688.
3. Zimmerman JJ. A history of adjunctive glucocorticoid treatment for pediatric sepsis: moving beyond steroid pulp fiction toward evidence-based medicine. Pediatr Crit Care Med. 2007;8: 530-539.
4. Markovitz BP, Goodman DM, Watson RS, et al. A retrospective cohort study of prognostic factors associated with outcome in pediatric severe sepsis: what is the role of steroids? Pediatr C r i t C a re M e d. 2005;6: 270-274.
5. Zimmerman JJ, Williams MD. Adjunctive corticosteroid therapy in pediatric severe sepsis: observations from the RESOLVE study. Pediatr Crit Care Med. 2011;12:2-8.
6. Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008;36:296-327.
7. Dellinger RP, Levy MM, Rhodes A, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Crit Care Med. 2013;39:165-228.
8. COIITSS Study Investigators, Annane D, Cariou A, et al. Corticosteroid treatment and intensive insulin therapy for septic shock in adults: a randomized controlled trial. JAMA. 2010;303:341-348.
9. Keh D, Sprung CL. Use of corticosteroid therapy in patients with sepsis and septic shock: an evidence-based review. Crit Care Med. 2004;32: S527-S533.
10. Sprung CL, Annane D, Keh D, et al. Hydrocortisone therapy for patients with septic shock. N Engl J Med. 2008;358:111-124.
11. Annane D, Sébille V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002;288:862-871.
12. Hebbar KB, Stockwell JA, Leong T, et al. Incidence of adrenal insufficiency and impact of corticosteroid supplementation in critically ill children with systemic inflammatory syndrome and vasopressor-dependent shock. Crit Care Med. 2011;39:1145-1150.
13. Menon K, Lawson M. Identification of adrenal insufficiency in pediatric critical illness. Pediatr C r i t C are M e d. 2007;8:276-278.
14. Hebbar KB, Petrillo T, Fortenberry JD. Adrenal insufficiency and response to corticosteroids in hypotensive critically ill children with cancer. J Crit Care. 2012;27:480-487.
15. Menon K, Ward RE, Lawson ML, et al. A prospective multicenter study of adrenal function in critically ill children. Am J Respir Crit Care Med. 2010;182:246-251.
16. Finfer S. Corticosteroids in septic shock. N Engl J Med. 2008;358:188-190.
17. Sarthi M, Lodha R, Vivekanandhan S, et al. Adrenal status in children with septic shock using low-dose stimulation test. Pediatr Crit Care Med. 2007;8:23-28.
18. Preissig CM, Hansen I, Roerig PL, et al. A protocolized approach to identify and manage hyperglycemia in a pediatric critical care unit. Pediatr Crit Care Med. 2008;9:581-588.
19. Menon K, McNally JD, Choong K, et al. A survey of stated physician practices and beliefs on the use of steroids in pediatric fluid and/or vasoactive infusion-dependent shock. Pediatr Crit Care Med. 2013;14:462-466.