Drug-Path: A database for drug-induced pathways

Database

Volumn 2015, Issue , 2015, Pages

  Zeng, Hui ^a   Qiu, Chengxiang ^b   Cui, Qinghua ^b  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

ANIMAL; COMPUTER LANGUAGE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC DATABASE; HUMAN; METABOLISM; PHARMACOKINETICS;

ANIMALS; DATABASES, GENETIC; GENE EXPRESSION REGULATION; HUMANS; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; PROGRAMMING LANGUAGES;

EID: 84943190030     PISSN: 17580463     EISSN: None     Source Type: Journal    
DOI: 10.1093/database/bav061     Document Type: Article

References (12)

1. Jewison, T., Su, Y., Disfany, F.M. et al. (2014) SMPDB 2.0: Big improvements to the small molecule pathway database. Nucleic Acids Res., 42, D478-D484.
2. Law, V., Knox, C., Djoumbou, Y. et al. (2014) DrugBank 4.0: Shedding new light on drug metabolism. Nucleic Acids Res., 42, D1091-D1097.
3. Wishart, D.S., Knox, C., Guo, A.C. et al. (2006) DrugBank: A comprehensive resource for in silico drug discovery and exploration. Nucleic Acids Res., 34, D668-D672.
4. Kanehisa, M. and Goto, S. (2000) KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res., 28, 27-30.
5. Ogata, H., Goto, S., Sato, K. et al. (1999) KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res., 27, 29-34.
6. Frolkis, A., Knox, C., Lim, E. et al. (2010) SMPDB: The small molecule pathway database. Nucleic Acids Res., 38, D480-D487.
7. Lamb, J., Crawford, E.D., Peck, D. et al. (2006) The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease. Science, 313, 1929-1935.
8. Iorio, F., Bosotti, R., Scacheri, E. et al. (2010) Discovery of drug mode of action and drug repositioning from transcriptional responses. Proc. Natl. Acad. Sci. U S A., 107, 14621-14626.
9. Dudley, J.T., Sirota, M., Shenoy, M. et al. (2011) Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease. Sci. Transl. Med., 3, 96-76.
10. Sirota, M., Dudley, J.T., Kim, J. et al. (2011) Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci. Transl. Med., 3, 96-77.
11. Jin, L., Tu, J., Jia, J. et al. (2014) Drug-repurposing identified the combination of Trolox C and Cytisine for the treatment of type 2 diabetes. J. Transl. Med., 12, 153.
12. Hu, G. and Agarwal, P. (2009) Human disease-drug network based on genomic expression profiles. PLoS One, 4, e6536.