메뉴 건너뛰기




Volumn 35, Issue 10, 2015, Pages 1570-1578

Hippocampal structure, metabolism, and inflammatory response after a 6-week intense aerobic exercise in healthy young adults: A controlled trial

Author keywords

brain morphometry; brain structures; hippocampus; inflammation; metabolism; MR spectroscopy; physical activity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLUTAMIC ACID; GLUTAMINE; INTERLEUKIN 6; N ACETYLASPARTIC ACID; TUMOR NECROSIS FACTOR ALPHA; ASPARTIC ACID; GLUTAMIC ACID DERIVATIVE; N-ACETYLASPARTATE;

EID: 84942984259     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2015.125     Document Type: Article
Times cited : (58)

References (40)
  • 1
    • 25444533023 scopus 로고    scopus 로고
    • Exercise enhances learning and hippocampal neurogenesis in aged mice
    • Van Praag H, Shubert T, Zhao C, Gage FH. Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci 2005; 25: 8680-8685.
    • (2005) J Neurosci , vol.25 , pp. 8680-8685
    • Van Praag, H.1    Shubert, T.2    Zhao, C.3    Gage, F.H.4
  • 3
    • 77957342026 scopus 로고    scopus 로고
    • A neuroimaging investigation of the association between aerobic fitness, hippocampal volume, and memory performance in preadolescent children
    • Chaddock L, Erickson KI, Prakash RS, Kim JS, Voss MW, Vanpatter M et al. A neuroimaging investigation of the association between aerobic fitness, hippocampal volume, and memory performance in preadolescent children. Brain Res 2010; 1358: 172-183.
    • (2010) Brain Res , Issue.1358 , pp. 172-183
    • Chaddock, L.1    Erickson, K.I.2    Prakash, R.S.3    Kim, J.S.4    Voss, M.W.5    Vanpatter, M.6
  • 6
    • 84892879964 scopus 로고    scopus 로고
    • The effects of physical activity and exercise on brain-derived neurotrophic factor in healthy humans: A review
    • Huang T, Larsen KT, Ried-Larsen M, Moller NC, Andersen LB. The effects of physical activity and exercise on brain-derived neurotrophic factor in healthy humans: a review. Scand J Med Sci Sports 2014; 24: 1-10.
    • (2014) Scand J Med Sci Sports , Issue.24 , pp. 1-10
    • Huang, T.1    Larsen, K.T.2    Ried-Larsen, M.3    Moller, N.C.4    Andersen, L.B.5
  • 7
    • 34247593771 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates AMPA receptor trafficking to post-synaptic densities via IP3R and TRPC calcium signaling
    • Nakata H, Nakamura S. Brain-derived neurotrophic factor regulates AMPA receptor trafficking to post-synaptic densities via IP3R and TRPC calcium signaling. FEBS Lett 2007; 581: 2047-2054.
    • (2007) FEBS Lett , vol.581 , pp. 2047-2054
    • Nakata, H.1    Nakamura, S.2
  • 8
    • 0030604660 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor, but not neurotrophin-3, prevents ischaemia-induced neuronal cell death in organotypic rat hippocampal slice cultures
    • Pringle AK, Sundstrom LE, Wilde GJ, Williams LR, Iannotti F. Brain-derived neurotrophic factor, but not neurotrophin-3, prevents ischaemia-induced neuronal cell death in organotypic rat hippocampal slice cultures. Neurosci Lett 1996; 211: 203-206.
    • (1996) Neurosci Lett , vol.211 , pp. 203-206
    • Pringle, A.K.1    Sundstrom, L.E.2    Wilde, G.J.3    Williams, L.R.4    Iannotti, F.5
  • 9
    • 34548499151 scopus 로고    scopus 로고
    • Exercise builds brain health: Key roles of growth factor cascades and inflammation
    • Cotman CW, Berchtold NC, Christie LA. Exercise builds brain health: key roles of growth factor cascades and inflammation. Trends Neurosci 2007; 30: 464-472.
    • (2007) Trends Neurosci , vol.30 , pp. 464-472
    • Cotman, C.W.1    Berchtold, N.C.2    Christie, L.A.3
  • 10
    • 33646472905 scopus 로고    scopus 로고
    • Aerobic exercise, but not flexibility/resistance exercise, reduces serum IL-18, CRP, and IL-6 independent of beta-blockers, BMI, and psychosocial factors in older adults
    • Kohut ML, McCann DA, Russell DW, Konopka DN, Cunnick JE, Franke WD et al. Aerobic exercise, but not flexibility/resistance exercise, reduces serum IL-18, CRP, and IL-6 independent of beta-blockers, BMI, and psychosocial factors in older adults. Brain Behav Immun 2006; 20: 201-209.
    • (2006) Brain Behav Immun , vol.20 , pp. 201-209
    • Kohut, M.L.1    McCann, D.A.2    Russell, D.W.3    Konopka, D.N.4    Cunnick, J.E.5    Franke, W.D.6
  • 12
    • 0032421570 scopus 로고    scopus 로고
    • The Mini-International Neuropsychiatric Interview (M.I.N.I.): The Development and Validation of A Structured Diagnostic Psychiatric Interview for DSM-IV and ICD-10
    • quiz
    • Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998; 59 (Suppl 20): 22-33, quiz 34-57.
    • (1998) J Clin Psychiatry , vol.59 , Issue.22-33 , pp. 34-57
    • Sheehan, D.V.1    Lecrubier, Y.2    Sheehan, K.H.3    Amorim, P.4    Janavs, J.5    Weiller, E.6
  • 13
    • 0016751408 scopus 로고
    • Patterns of hand preference in a student population
    • Briggs GG, Nebes RD. Patterns of hand preference in a student population. Cortex 1975; 11: 230-238.
    • (1975) Cortex , vol.11 , pp. 230-238
    • Briggs, G.G.1    Nebes, R.D.2
  • 14
    • 0019859778 scopus 로고
    • Lactate kinetics and individual anaerobic threshold
    • Stegmann H, Kindermann W, Schnabel A. Lactate kinetics and individual anaerobic threshold. Int J Sports Med 1981; 2: 160-165.
    • (1981) Int J Sports Med , vol.2 , pp. 160-165
    • Stegmann, H.1    Kindermann, W.2    Schnabel, A.3
  • 15
    • 84861414424 scopus 로고    scopus 로고
    • Within-subject template estimation for unbiased longitudinal image analysis
    • Reuter M, Schmansky NJ, Rosas HD, Fischl B. Within-subject template estimation for unbiased longitudinal image analysis. Neuroimage 2012; 61: 1402-1418.
    • (2012) Neuroimage , Issue.61 , pp. 1402-1418
    • Reuter, M.1    Schmansky, N.J.2    Rosas, H.D.3    Fischl, B.4
  • 16
  • 17
    • 37349069492 scopus 로고    scopus 로고
    • Be smart, exercise your heart: Exercise effects on brain and cognition
    • Hillman CH, Erickson KI, Kramer AF. Be smart, exercise your heart: exercise effects on brain and cognition. Nat Rev Neurosci 2008; 9: 58-65.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 58-65
    • Hillman, C.H.1    Erickson, K.I.2    Kramer, A.F.3
  • 18
    • 84925225912 scopus 로고    scopus 로고
    • Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults
    • Brickman AM, Khan UA, Provenzano FA, Yeung LK, Suzuki W, Schroeter H et al. Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults. Nat Neurosci 2014; 17: 1798-1803.
    • (2014) Nat Neurosci , Issue.17 , pp. 1798-1803
    • Brickman, A.M.1    Khan, U.A.2    Provenzano, F.A.3    Yeung, L.K.4    Suzuki, W.5    Schroeter, H.6
  • 19
    • 84883195920 scopus 로고    scopus 로고
    • The effect of aerobic exercise on cortical architecture in patients with chronic schizophrenia: A randomized controlled MRI study
    • Falkai P, Malchow B, Wobrock T, Gruber O, Schmitt A, Honer WG et al. The effect of aerobic exercise on cortical architecture in patients with chronic schizophrenia: a randomized controlled MRI study. Eur Arch Psychiatry Clin Neurosci 2013; 263: 469-473.
    • (2013) Eur Arch Psychiatry Clin Neurosci , Issue.263 , pp. 469-473
    • Falkai, P.1    Malchow, B.2    Wobrock, T.3    Gruber, O.4    Schmitt, A.5    Honer, W.G.6
  • 20
    • 84962467611 scopus 로고    scopus 로고
    • The hippocampus and exercise: Histological correlates of MR-detected volume changes
    • e-pub ahead of print 01 January 2014
    • Biedermann SV, Fuss J, Steinle J, Auer MK, Dormann C, Falfan-Melgoza C et al. The hippocampus and exercise: histological correlates of MR-detected volume changes. Brain Struct Funct e-pub ahead of print 01 January 2014; doi: 10.1007/s00429-014-0976-5.
    • Brain Struct Funct
    • Biedermann, S.V.1    Fuss, J.2    Steinle, J.3    Auer, M.K.4    Dormann, C.5    Falfan-Melgoza, C.6
  • 23
    • 84859213881 scopus 로고    scopus 로고
    • Plasticity in gray and white: Neuroimaging changes in brain structure during learning
    • Zatorre RJ, Fields RD, Johansen-Berg H. Plasticity in gray and white: neuroimaging changes in brain structure during learning. Nat Neurosci 2012; 15: 528-536.
    • (2012) Nat Neurosci , Issue.15 , pp. 528-536
    • Zatorre, R.J.1    Fields, R.D.2    Johansen-Berg, H.3
  • 24
    • 0028080101 scopus 로고
    • Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization
    • Pellerin L, Magistretti PJ. Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc Natl Acad Sci USA 1994; 91: 10625-10629.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10625-10629
    • Pellerin, L.1    Magistretti, P.J.2
  • 26
    • 84857855562 scopus 로고    scopus 로고
    • Different circulating brain-derived neurotrophic factor responses to acute exercise between physically active and sedentary subjects
    • Nofuji Y, Suwa M, Sasaki H, Ichimiya A, Nishichi R, Kumagai S. Different circulating brain-derived neurotrophic factor responses to acute exercise between physically active and sedentary subjects. J Sports Sci Med 2012; 11: 83-88.
    • (2012) J Sports Sci Med , Issue.11 , pp. 83-88
    • Nofuji, Y.1    Suwa, M.2    Sasaki, H.3    Ichimiya, A.4    Nishichi, R.5    Kumagai, S.6
  • 27
    • 63649104503 scopus 로고    scopus 로고
    • Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men
    • Zoladz JA, Pilc A, Majerczak J, Grandys M, Zapart-Bukowska J, Duda K. Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. J Physiol Pharmacol 2008; 59: 119-132.
    • (2008) J Physiol Pharmacol , vol.59 , pp. 119-132
    • Zoladz, J.A.1    Pilc, A.2    Majerczak, J.3    Grandys, M.4    Zapart-Bukowska, J.5    Duda, K.6
  • 28
    • 80053053528 scopus 로고    scopus 로고
    • Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males
    • Griffin EW, Mullally S, Foley C, Warmington SA, O'Mara SM, Kelly AM. Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males. Physiol Behav 2011; 104: 934-941.
    • (2011) Physiol Behav , Issue.104 , pp. 934-941
    • Griffin, E.W.1    Mullally, S.2    Foley, C.3    Warmington, S.A.4    O'Mara, S.M.5    Kelly, A.M.6
  • 29
    • 65649139911 scopus 로고    scopus 로고
    • Effects of strength and endurance training on brain-derived neurotrophic factor and insulin-like growth factor 1 in humans
    • Schiffer T, Schulte S, Hollmann W, Bloch W, Struder HK. Effects of strength and endurance training on brain-derived neurotrophic factor and insulin-like growth factor 1 in humans. Horm Metab Res 2009; 41: 250-254.
    • (2009) Horm Metab Res , vol.41 , pp. 250-254
    • Schiffer, T.1    Schulte, S.2    Hollmann, W.3    Bloch, W.4    Struder, H.K.5
  • 30
    • 71249157791 scopus 로고    scopus 로고
    • The diseasome of physical inactivity-And the role of myokines in muscle-fat cross talk
    • Pedersen BK. The diseasome of physical inactivity-And the role of myokines in muscle-fat cross talk. J Physiol 2009; 587: 5559-5568.
    • (2009) J Physiol , vol.587 , pp. 5559-5568
    • Pedersen, B.K.1
  • 31
    • 15444374348 scopus 로고
    • The anti-inflammatory effect of exercise
    • Petersen AM, Pedersen BK. The anti-inflammatory effect of exercise. J Appl Physiol (1985) 2005; 98: 1154-1162.
    • (1985) J Appl Physiol. , vol.2005 , Issue.98 , pp. 1154-1162
    • Petersen, A.M.1    Pedersen, B.K.2
  • 32
    • 23044475503 scopus 로고    scopus 로고
    • Dramatic elevations of interleukin-6 and acute-phase reactants in athletes participating in the ultradistance foot race spartathlon: Severe systemic inflammation and lipid and lipoprotein changes in protracted exercise
    • Margeli A, Skenderi K, Tsironi M, Hantzi E, Matalas AL, Vrettou C et al. Dramatic elevations of interleukin-6 and acute-phase reactants in athletes participating in the ultradistance foot race spartathlon: severe systemic inflammation and lipid and lipoprotein changes in protracted exercise. J Clin Endocrinol Metab 2005; 90: 3914-3918.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3914-3918
    • Margeli, A.1    Skenderi, K.2    Tsironi, M.3    Hantzi, E.4    Matalas, A.L.5    Vrettou, C.6
  • 33
    • 21844448903 scopus 로고    scopus 로고
    • Microglia-derived tumor necrosis factor-Alpha exaggerates death of newborn hippocampal progenitor cells in vitro
    • Cacci E, Claasen JH, Kokaia Z. Microglia-derived tumor necrosis factor-Alpha exaggerates death of newborn hippocampal progenitor cells in vitro. J Neurosci Res 2005; 80: 789-797.
    • (2005) J Neurosci Res , vol.80 , pp. 789-797
    • Cacci, E.1    Claasen, J.H.2    Kokaia, Z.3
  • 34
    • 0036522961 scopus 로고    scopus 로고
    • Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: Elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism
    • Lebon V, Petersen KF, Cline GW, Shen J, Mason GF, Dufour S et al. Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism. J Neurosci 2002; 22: 1523-1531.
    • (2002) J Neurosci , vol.22 , pp. 1523-1531
    • Lebon, V.1    Petersen, K.F.2    Cline, G.W.3    Shen, J.4    Mason, G.F.5    Dufour, S.6
  • 35
    • 84861336837 scopus 로고    scopus 로고
    • In vivo voxel based morphometry: Detection of increased hippocampal volume and decreased glutamate levels in exercising mice
    • Biedermann S, Fuss J, Zheng L, Sartorius A, Falfan-Melgoza C, Demirakca T et al. In vivo voxel based morphometry: detection of increased hippocampal volume and decreased glutamate levels in exercising mice. Neuroimage 2012; 61: 1206-1212.
    • (2012) Neuroimage , vol.61 , pp. 1206-1212
    • Biedermann, S.1    Fuss, J.2    Zheng, L.3    Sartorius, A.4    Falfan-Melgoza, C.5    Demirakca, T.6
  • 36
    • 0034907183 scopus 로고    scopus 로고
    • Amygdalar and hippocampal volumetry in control participants: Differences regarding handedness
    • Szabo CA, Xiong J, Lancaster JL, Rainey L, Fox P. Amygdalar and hippocampal volumetry in control participants: differences regarding handedness. AJNR Am J Neuroradiol 2001; 22: 1342-1345.
    • (2001) AJNR Am J Neuroradiol , vol.22 , pp. 1342-1345
    • Szabo, C.A.1    Xiong, J.2    Lancaster, J.L.3    Rainey, L.4    Fox, P.5
  • 37
    • 0037992920 scopus 로고    scopus 로고
    • Asymmetrical allocation of NMDA receptor epsilon2 subunits in hippocampal circuitry
    • Kawakami R, Shinohara Y, Kato Y, Sugiyama H, Shigemoto R, Ito I. Asymmetrical allocation of NMDA receptor epsilon2 subunits in hippocampal circuitry. Science 2003; 300: 990-994.
    • (2003) Science , vol.300 , pp. 990-994
    • Kawakami, R.1    Shinohara, Y.2    Kato, Y.3    Sugiyama, H.4    Shigemoto, R.5    Ito, I.6
  • 38
    • 58049208202 scopus 로고    scopus 로고
    • Leftright asymmetry of the hippocampal synapses with differential subunit allocation of glutamate receptors
    • Shinohara Y, Hirase H, Watanabe M, Itakura M, Takahashi M, Shigemoto R. Leftright asymmetry of the hippocampal synapses with differential subunit allocation of glutamate receptors. Proc Natl Acad Sci USA 2008; 105: 19498-19503.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19498-19503
    • Shinohara, Y.1    Hirase, H.2    Watanabe, M.3    Itakura, M.4    Takahashi, M.5    Shigemoto, R.6
  • 39
    • 84904215504 scopus 로고    scopus 로고
    • Asymmetrical expression of BDNF and NTRK3 genes in frontoparietal cortex of stressresilient rats in an animal model of depression
    • Farhang S, Barar J, Fakhari A, Mesgariabbasi M, Khani S, Omidi Y et al. Asymmetrical expression of BDNF and NTRK3 genes in frontoparietal cortex of stressresilient rats in an animal model of depression. Synapse 2014; 68: 387-393.
    • (2014) Synapse , Issue.68 , pp. 387-393
    • Farhang, S.1    Barar, J.2    Fakhari, A.3    Mesgariabbasi, M.4    Khani, S.5    Omidi, Y.6
  • 40
    • 70149088982 scopus 로고    scopus 로고
    • Expression of hippocampal brain-derived neurotrophic factor and its receptors in Stanley consortium brains
    • Dunham JS, Deakin JF, Miyajima F, Payton A, Toro CT. Expression of hippocampal brain-derived neurotrophic factor and its receptors in Stanley consortium brains. J Psychiatr Res 2009; 43: 1175-1184.
    • (2009) J Psychiatr Res , vol.43 , pp. 1175-1184
    • Dunham, J.S.1    Deakin, J.F.2    Miyajima, F.3    Payton, A.4    Toro, C.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.