In vivo voxel based morphometry: Detection of increased hippocampal volume and decreased glutamate levels in exercising mice

NeuroImage

Volumn 61, Issue 4, 2012, Pages 1206-1212

  Biedermann, Sarah ^a   Fuss, Johannes ^a   Zheng, Lei ^a,b   Sartorius, Alexander ^a   Falfán Melgoza, Claudia ^a   Demirakca, Traute ^a   Gass, Peter ^a   Ende, Gabriele ^a   Weber Fahr, Wolfgang ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

1H MRS; Glutamate; Hippocampus; VBM; Voluntary wheel running

Indexed keywords

GLUTAMIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN LEVEL; BRAIN METABOLISM; BRAIN SIZE; BRAIN TISSUE; CONTROLLED STUDY; EXERCISE; GRAY MATTER; HIPPOCAMPUS; IMAGE ANALYSIS; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RUNNING; SIGNAL NOISE RATIO; STRUCTURE ANALYSIS; VOLUNTARY MOVEMENT; VOXEL BASED MORPHOMETRY;

ANIMALS; GLUTAMIC ACID; HIPPOCAMPUS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL; PHYSICAL CONDITIONING, ANIMAL;

EID: 84861336837     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2012.04.010     Document Type: Article

References (34)

1. Ashburner J. A fast diffeomorphic image registration algorithm. Neuroimage 2007, 38:95-113.
2. Ashburner J., Friston K.J. Voxel-based morphometry-the methods. Neuroimage 2000, 11(6 Pt. 1):805-821.
3. Bland S.T., Gonzales R.A., Schallert T. Movement-related glutamate levels in rat hippocampus, striatum, and sensorimotor cortex. Neurosci. Lett. 1999, 277:119-122.
4. Bugg J.M., Head D. Exercise moderates age-related atrophy of the medial temporal lobe. Neurobiol. Aging 2011, 32(3):506-514.
5. Clark P.J., Brzezinska W.J., Puchalski E.K., Krone D.A., Rhodes J.S. Functional analysis of neurovascular adaptations to exercise in the dentate gyrus of young adult mice associated with cognitive gain. Hippocampus 2009, 19:937-950.
6. Colcombe S.J., Erickson K.I., Scalf P.E., Kim J.S., Prakash R., McAuley E., Elavsky S., Marquez D.X., Hu L., Kramer A.F. Aerobic exercise training increases brain volume in aging humans. J. Gerontol. A Biol. Sci. Med. Sci. 2006, 61:1166-1170.
7. de Graaf R.A., Brown P.B., McIntyre S., Nixon T.W., Behar K.L., Rothman D.L. High magnetic field water and metabolite proton T1 and T2 relaxation in rat brain in vivo. Magn. Reson. Med. 2006, 56:386-394.
8. Driscoll I., Hamilton D.A., Petropoulos H., Yeo R.A., Brooks W.M., Baumgartner R.N., Sutherland R.J. The aging hippocampus: cognitive, biochemical and structural findings. Cereb. Cortex 2003, 13(12):1344-1351.
9. Erickson K.I., Prakash R.S., Voss M.W., Chaddock L., Hu L., Morris K.S., White S.M., Wojcicki T.R., McAuley E., Kramer A.F. Aerobic fitness is associated with hippocampal volume in elderly humans. Hippocampus 2009, 19(10):1030-1039.
10. Farmer J., Zhao X., van Praag H., Wodtke K., Gage F.H., Christie B.R. Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience 2004, 124:71-79.
11. Fuss J., Gass P. Endocannabinoids and voluntary activity in mice: runner's high and long-term consequences in emotional behaviors. Exp. Neurol. 2010, 224:103-105.
12. Fuss J., Ben Abdallah N.M., Hensley F.W., Weber K.J., Hellweg R., Gass P. Deletion of running-induced hippocampal neurogenesis by irradiation prevents development of an anxious phenotype in mice. PLoS One 2010, 5.
13. Fuss J., Ben Abdallah N.M., Vogt M.A., Touma C., Pacifici P.G., Palme R., Witzemann V., Hellweg R., Gass P. Voluntary exercise induces anxiety-like behavior in adult C57BL/6J mice correlating with hippocampal neurogenesis. Hippocampus 2010, 20:364-376.
14. Kantarci K. 1H magnetic resonance spectroscopy in dementia. Br. J. Radiol. 2007, 80(Spec. No. 2):S146-S152.
15. Koehl M., Meerlo P., Gonzales D., Rontal A., Turek F.W., Abrous D.N. Exercise-induced promotion of hippocampal cell proliferation requires beta-endorphin. FASEB J. 2008, 22:2253-2262.
16. Kovacevic N., Henderson J.T., Chan E., Lifshitz N., Bishop J., Evans A.C., Henkelman R.M., Chen X.J. A three-dimensional MRI atlas of the mouse brain with estimates of the average and variability. Cereb. Cortex 2005, 15:639-645.
17. Lau J.C., Lerch J.P., Sled J.G., Henkelman R.M., Evans A.C., Bedell B.J. Longitudinal neuroanatomical changes determined by deformation-based morphometry in a mouse model of Alzheimer's disease. Neuroimage 2008, 42(1):19-27.
18. Lightfoot J.T., Turner M.J., Daves M., Vordermark A., Kleeberger S.R. Genetic influence on daily wheel running activity level. Physiol. Genomics 2004, 19:270-276.
19. Llorens-Martin, M., Tejeda, G.S., Trejo, J.L., 2010. Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: a dual birthdating analysis. PLoS One 5, e12188.
20. Louissaint A., Rao S., Leventhal C., Goldman S.A. Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron 2002, 34:945-960.
21. 1H-MRS study. Neuroimage 2011, 57(4):1324-1330.
22. Meeusen R., Piacentini M.F., De Meirleir K. Brain microdialysis in exercise research. Sports Med. 2001, 31:965-983.
23. Pajonk F.G., Wobrock T., Gruber O., Scherk H., Berner D., Kaizl I., Kierer A., Muller S., Oest M., Meyer T., Backens M., Schneider-Axmann T., Thornton A.E., Honer W.G., Falkai P. Hippocampal plasticity in response to exercise in schizophrenia. Arch. Gen. Psychiatry 2010, 67:133-143.
24. Palmer T.D., Willhoite A.R., Gage F.H. Vascular niche for adult hippocampal neurogenesis. J. Comp. Neurol. 2000, 425:479-494.
25. Pereira A.C., Huddleston D.E., Brickman A.M., Sosunov A.A., Hen R., McKhann G.M., Sloan R., Gage F.H., Brown T.R., Small S.A. An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:5638-5643.
26. Pfeuffer J., Tkac I., Provencher S.W., Gruetter R. Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain. J. Magn. Reson. 1999, 141:104-120.
27. Sawiak S.J., Wood N.I., Williams G.B., Morton A.J., Carpenter T.A. Voxel-based morphometry in the R6/2 transgenic mouse reveals differences between genotypes not seen with manual 2D morphometry. Neurobiol. Dis. 2009, 33(1):20-27.
28. Sawrie S.M., Martin R.C., Knowlton R., Faught E., Gilliam F., Kuzniecky R. Relationships among hippocampal volumetry, proton magnetic resonance spectroscopy, and verbal memory in temporal lobe epilepsy. Epilepsia 2001, 42:1403-1407.
29. Smith S.M. Fast robust automated brain extraction. Hum. Brain Mapp. 2002, 17(3):143-155.
30. Smith S.M., Jenkinson M., Woolrich M.W., Beckmann C.F., Behrens T.E., Johansen-Berg H., Bannister P.R., De Luca M., Drobnjak I., Flitney D.E., Niazy R.K., Saunders J., Vickers J., Zhang Y., De Stefano N., Brady J.M., Matthews P.M. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004, 23(Suppl. 1):S208-S219.
31. van Praag H., Christie B.R., Sejnowski T.J., Gage F.H. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:13427-13431.
32. van Praag H., Kempermann G., Gage F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 1999, 2:266-270.
33. Yuede C.M., Zimmerman S.D., Dong H., Kling M.J., Bero A.W., Holtzman D.M., Timson B.F., Csernansky J.G. Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease. Neurobiol. Dis. 2009, 35:426-432.
34. Zhang J., Peng Q., Li Q., Jahanshad N., Hou Z., Jiang M., Masuda N., Langbehn D.R., Miller M.I., Mori S., Ross C.A., Duan W. Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images. Neuroimage 2010, 49(3):2340-2351.