Comorbidity as a driver of adverse outcomes in people with chronic kidney disease

Kidney International

Volumn 88, Issue 4, 2015, Pages 859-866

  Tonelli, Marcello ^a   Wiebe, Natasha ^b   Guthrie, Bruce ^c   James, Matthew T ^a   Quan, Hude ^d   Fortin, Martin ^e   Klarenbach, Scott W ^b   Sargious, Peter ^f   Straus, Sharon ^g   Lewanczuk, Richard ^f   Ronksley, Paul E ^d   Manns, Braden J ^a   Hemmelgarn, Brenda R ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d UNIVERSITY OF CALGARY   (Canada)

^e UNIVERSITÉ DE SHERBROOKE   (Canada)

^f ALBERTA HEALTH SERVICES   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

chronic kidney disease; comorbidity

Indexed keywords

ADULT; ADVERSE OUTCOME; ALGORITHM; ARTICLE; CANADA; CHRONIC KIDNEY DISEASE; CHRONIC PAIN; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HEART INFARCTION; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; AGED; ALBERTA; FACTUAL DATABASE; MENTAL DISORDERS; MIDDLE AGED; MYOCARDIAL INFARCTION; PROGNOSIS; RENAL INSUFFICIENCY, CHRONIC; TIME FACTOR; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ALBERTA; DATABASES, FACTUAL; FEMALE; HOSPITALIZATION; HUMANS; MALE; MENTAL DISORDERS; MIDDLE AGED; MYOCARDIAL INFARCTION; PROGNOSIS; RENAL INSUFFICIENCY, CHRONIC; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; YOUNG ADULT;

EID: 84942982080     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2015.228     Document Type: Article

References (25)

1. Fortin M, Lapointe L, Hudon C et al. Multimorbidity is common to family practice. Is it commonly researched? Can Fam Physician 2005; 51: 244-245.
2. Barnett K, Mercer SW, Norbury M et al. Epidemiology of multimorbidity and implications for health care, research, and medical education: A crosssectional study. Lancet 2012; 380: 37-43.
3. Fortin M, Hudon C, Haggerty J et al. Prevalence estimates of multimorbidity: A comparative study of two sources. BMC Health Serv Res 2010; 10: 111.
4. Lehnert T, Heider D, Leicht H et al. Review: health care utilization and costs of elderly persons with multiple chronic conditions. Med Care Res Rev 2011; 68: 387-420.
5. Perruccio AV, Katz JN, Losina E. Health burden in chronic disease: multimorbidity is associated with self-rated health more than medical comorbidity alone. J Clin Epidemiol 2012; 65: 100-106.
6. Parekh AK, Goodman RA, Gordon C et al. Managing multiple chronic conditions: A strategic framework for improving health outcomes and quality of life. Public Health Rep 2011; 126: 460-471.
7. Hemmelgarn BR, Manns BJ, Lloyd A et al. Relation between kidney function, proteinuria, and adverse outcomes. JAMA 2010; 303: 423-429.
8. Piette JD, Kerr EA. The impact of comorbid chronic conditions on diabetes care. Diabetes Care 2006; 29: 725-731.
9. Stevens PE, Levin A, Kidney Disease: improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group M. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med 2013; 158: 825-830.
10. Petit-Zeman S, Firkins L, Scadding JW. The James Lind Alliance: tackling research mismatches. Lancet 2010; 376: 667-669.
11. Boyd CM, Darer J, Boult C et al. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA 2005; 294: 716-724.
12. Fortin M, Contant E, Savard C et al. Canadian guidelines for clinical practice: An analysis of their quality and relevance to the care of adults with comorbidity. BMC Fam Pract 2011; 12: 74.
13. Shippee ND, Shah ND, May CR et al. Cumulative complexity: A functional, patient-centered model of patient complexity can improve research and practice. J Clin Epidemiol 2012; 65: 1041-1051.
14. Rettig RA, Vargas RB, Norris KC et al. Chronic kidney disease-a quiet revolution in nephrology. RAND Health Quarterly 2011; 1: 9.
15. Kadam UT, Uttley J, Jones PW et al. Chronic disease multimorbidity transitions across healthcare interfaces and associated costs: A clinicallinkage database study. BMJ Open 2013; 3.
16. Woodhead C, Ashworth M, Schofield P et al. Patterns of physical co-/multimorbidity among patients with serious mental illness: A London boroughbased cross-sectional study. BMC Fam Pract 2014; 15: 117.
17. Arffman M, Forssas E, Ruuth I et al. Changes in multimorbidity among people with diabetes in Finland 1990-2011. Eur J Public Health 2014; 24 (http://eurpub. oxfordjournals. org/content/24/suppl-2/cku165. 084).
18. Shlipak MG, Fried LF, Cushman M et al. Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. JAMA 2005; 293: 1737-1745.
19. Diederichs C, Berger K, Bartels DB. The measurement of multiple chronic diseases-a systematic review on existing multimorbidity indices. J Gerontol A Biol Sci Med Sci 2011; 66: 301-311.
20. von Elm E, Altman DG, Egger M et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 2007; 370: 1453-1457.
21. Hemmelgarn BR, Clement F, Manns BJ et al. Overview of the Alberta Kidney Disease Network. BMC Nephrol 2009; 10: 30.
22. Tonelli M, Wiebe N, Martin F et al. Methods for identifying 30 chronic conditions: Application to administrative data. BMC Med Inform Decis Mak 2015; 15: 31.
23. Austin PC, Daly PA, Tu JV. A multicenter study of the coding accuracy of hospital discharge administrative data for patients admitted to cardiac care units in Ontario. Am Heart J 2002; 144: 290-296.
24. Rockhill B, Newman B, Weinberg C. Use and misuse of population attributable fractions. Am J Public Health 1998; 88: 15-19.
25. Redelmeier DA, Tan SH, Booth GL. The treatment of unrelated disorders in patients with chronic medical diseases. N Engl J Med 1998; 338: 1516-1520.