Neto2-null mice have impaired GABAergic inhibition and are susceptible to seizures

Frontiers in Cellular Neuroscience

Volumn 9, Issue September, 2015, Pages

  Mahadevan, Vivek ^a   Dargaei, Zahra ^a   Ivakine, Evgueni A ^b   Hartmann, Anna Maria ^c   Ng, David ^b,d   Chevrier, Jonah ^a   Ormond, Jake ^a,e   Nothwang, Hans Gerd ^c   McInnes, Roderick R ^b,f   Woodin, Melanie A ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF OLDENBURG   (Germany)

^d Departments of Neuroscience Biochemistry and Molecular Biophysics Columbia University ^*  (United States)

^e RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^f MCGILL UNIVERSITY   (Canada)

Author keywords

Auxiliary subunit; Chloride; GABA; Hippocampus; Inhibition; KCC2; Neto proteins; Seizure; Transporter

Indexed keywords

4 AMINOBUTYRIC ACID; GRAMICIDIN; MEMBRANE PROTEIN; NETO2 PROTEIN; PENTETRAZOLE; POTASSIUM CHLORIDE COTRANSPORTER 2; UNCLASSIFIED DRUG;

ADULT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; BIOTINYLATION; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FLUX ASSAY; GABAERGIC TRANSMISSION; HIPPOCAMPUS; HOMEOSTASIS; INHIBITORY POSTSYNAPTIC POTENTIAL; LATENT PERIOD; MOUSE; NONHUMAN; PENTYLENETETRAZOLE-INDUCED SEIZURE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; WESTERN BLOTTING;

EID: 84942936764     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2015.00368     Document Type: Article

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