메뉴 건너뛰기




Volumn 10, Issue 8, 2015, Pages 1133-1141

Pulmonary large-cell neuroendocrine carcinoma from epidemiology to therapy

Author keywords

Cancer treatment.; Large cell neuroendocrine carcinoma; Lung neuroendocrine tumors; Pathologic characterization

Indexed keywords

AMRUBICIN; CD56 ANTIGEN; CHROMOGRANIN A; CISPLATIN; CYTOKERATIN 5; CYTOKERATIN 6; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; IRINOTECAN; MOLECULAR MARKER; NAPSIN A; PROTEIN P40; PROTEIN P63; SYNAPTOPHYSIN; THYROID TRANSCRIPTION FACTOR 1; UNCLASSIFIED DRUG; VINBLASTINE; ANTINEOPLASTIC AGENT; QUINAZOLINE DERIVATIVE;

EID: 84942928775     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0000000000000589     Document Type: Review
Times cited : (199)

References (73)
  • 3
    • 0025768416 scopus 로고
    • Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases
    • Travis WD, Linnoila RI, Tsokos MG, et al. Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases. Am J Surg Pathol 1991;15:529-553
    • (1991) Am J Surg Pathol , vol.15 , pp. 529-553
    • Travis, W.D.1    Linnoila, R.I.2    Tsokos, M.G.3
  • 4
    • 78249262321 scopus 로고    scopus 로고
    • Neuroendocrine tumors of the lung: An update
    • Rekhtman N. Neuroendocrine tumors of the lung: an update. Arch Pathol Lab Med 2010;134:1628-1638
    • (2011) Arch Pathol Lab Med , vol.134 , pp. 1628-1638
    • Rekhtman, N.1
  • 5
    • 79958077774 scopus 로고    scopus 로고
    • Should large cell neuroendocrine lung carcinoma be classified and treated as a small cell lung cancer or with other large cell carcinomas?
    • Varlotto JM, Medford-Davis LN, Recht A, et al. Should large cell neuroendocrine lung carcinoma be classified and treated as a small cell lung cancer or with other large cell carcinomas? J Thorac Oncol 2011;6:1050-1058
    • (2011) J Thorac Oncol , vol.6 , pp. 1050-1058
    • Varlotto, J.M.1    Medford-Davis, L.N.2    Recht, A.3
  • 6
    • 0037069169 scopus 로고    scopus 로고
    • Feasibility of the new WHO classification of pulmonary neuroendocrine tumours
    • Younossian AB, Brndler MA, Ttsch M. Feasibility of the new WHO classification of pulmonary neuroendocrine tumours. Swiss Med Wkly 2002;132:535-540
    • (2002) Swiss Med Wkly , vol.132 , pp. 535-540
    • Younossian, A.B.1    Brndler, M.A.2    Ttsch, M.3
  • 7
    • 33845506834 scopus 로고    scopus 로고
    • Large-cell neuroendocrine carcinoma of the lung: An aggressive neuroendocrine lung cancer
    • Fernandez FG, Battafarano RJ. Large-cell neuroendocrine carcinoma of the lung: an aggressive neuroendocrine lung cancer. Semin Thorac Cardiovasc Surg 2006;18:206-210
    • (2006) Semin Thorac Cardiovasc Surg , vol.18 , pp. 206-210
    • Fernandez, F.G.1    Battafarano, R.J.2
  • 8
    • 84906937296 scopus 로고    scopus 로고
    • Diagnosis and treatment of neuroendocrine lung tumors
    • Snchez de Cos Escun J. Diagnosis and treatment of neuroendocrine lung tumors. Arch Bronconeumol 2014;50:392-396
    • (2014) Arch Bronconeumol , vol.50 , pp. 392-396
    • De Cos Snchez, E.J.1
  • 9
    • 0031926911 scopus 로고    scopus 로고
    • Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid
    • Travis WD, Rush W, Flieder DB, et al. Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid. Am J Surg Pathol 1998;22:934-944
    • (1998) Am J Surg Pathol , vol.22 , pp. 934-944
    • Travis, W.D.1    Rush, W.2    Flieder, D.B.3
  • 11
    • 33644842195 scopus 로고    scopus 로고
    • Neuroendocrine neoplasms of the lung: A prognostic spectrum
    • Asamura H, Kameya T, Matsuno Y, et al. Neuroendocrine neoplasms of the lung: a prognostic spectrum. J Clin Oncol 2006;24:70-76
    • (2006) J Clin Oncol , vol.24 , pp. 70-76
    • Asamura, H.1    Kameya, T.2    Matsuno, Y.3
  • 12
    • 9144259302 scopus 로고    scopus 로고
    • CT findings of surgically resected large cell neuroendocrine carcinoma of the lung in 38 patients
    • Oshiro Y, Kusumoto M, Matsuno Y, et al. CT findings of surgically resected large cell neuroendocrine carcinoma of the lung in 38 patients. AJR Am J Roentgenol 2004;182:87-91
    • (2004) AJR Am J Roentgenol , vol.182 , pp. 87-91
    • Oshiro, Y.1    Kusumoto, M.2    Matsuno, Y.3
  • 13
    • 58649099238 scopus 로고    scopus 로고
    • International Staging Committee and Participating Institutions. The IASLC Lung Cancer Staging Project: Proposals for the inclusion of broncho-pulmonary carcinoid tumors in the forthcoming (seventh) edition of the TNM Classification for Lung Cancer
    • Travis WD, Giroux DJ, Chansky K, et al; International Staging Committee and Participating Institutions. The IASLC Lung Cancer Staging Project: proposals for the inclusion of broncho-pulmonary carcinoid tumors in the forthcoming (seventh) edition of the TNM Classification for Lung Cancer. J Thorac Oncol 2008;3:1213-1223
    • (2008) J Thorac Oncol , vol.3 , pp. 1213-1223
    • Travis, W.D.1    Giroux, D.J.2    Chansky, K.3
  • 14
    • 0035212220 scopus 로고    scopus 로고
    • Expression of somatostatin receptor types 2, 3, and 5 in biopsies and specimens of human lung tumours
    • Papotti M, Croce S, Bello M, et al. Expression of somatostatin receptor types 2, 3, and 5 in biopsies and specimens of human lung tumours. Virchows Arch 2001;439:787-797
    • (2001) Virchows Arch , vol.439 , pp. 787-797
    • Papotti, M.1    Croce, S.2    Bello, M.3
  • 15
    • 33646411263 scopus 로고    scopus 로고
    • Comparison of 111In-DOTADPhe1-Tyr3-octreotideand 111In-DOTA-lanreotide scintigraphy and dosimetry in patients with neuroendocrine tumours
    • Rodrigues M, Traub-Weidinger T, Li S, et al. Comparison of 111In-DOTADPhe1-Tyr3-octreotideand 111In-DOTA-lanreotide scintigraphy and dosimetry in patients with neuroendocrine tumours. Eur J Nucl Med Mol Imaging 2006;33:532-540
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , pp. 532-540
    • Rodrigues, M.1    Traub-Weidinger, T.2    Li, S.3
  • 17
    • 34447572628 scopus 로고    scopus 로고
    • Pulmonary large cell neuroendocrine carcinoma: Its place in the spectrum of pulmonary carcinoma
    • Iyoda A, Hiroshima K, Nakatani Y, Fujisawa T. Pulmonary large cell neuroendocrine carcinoma: its place in the spectrum of pulmonary carcinoma. Ann Thorac Surg 2007;84:702-707
    • (2007) Ann Thorac Surg , vol.84 , pp. 702-707
    • Iyoda, A.1    Hiroshima, K.2    Nakatani, Y.3    Fujisawa, T.4
  • 18
    • 84919443808 scopus 로고    scopus 로고
    • A retrospective analysis of the clinicopathological characteristics of large cell carcinoma of the lung
    • Liang R, Chen TX, Wang ZQ, et al. A retrospective analysis of the clinicopathological characteristics of large cell carcinoma of the lung. Exp Ther Med 2015;9:197-202
    • (2015) Exp Ther Med , vol.9 , pp. 197-202
    • Liang, R.1    Chen, T.X.2    Wang, Z.Q.3
  • 19
    • 84893702750 scopus 로고    scopus 로고
    • Large cell carcinoma of the lung: Clinically oriented classification integrating immunohistochemistry and molecular biology
    • Rossi G, Mengoli MC, Cavazza A, et al. Large cell carcinoma of the lung: clinically oriented classification integrating immunohistochemistry and molecular biology. Virchows Arch 2014;464:61-68
    • (2014) Virchows Arch , vol.464 , pp. 61-68
    • Rossi, G.1    Mengoli, M.C.2    Cavazza, A.3
  • 20
    • 21744449312 scopus 로고    scopus 로고
    • Large cell neuroendocrine carcinoma: An aggressive form of non-small cell lung cancer
    • Battafarano RJ, Fernandez FG, Ritter J, et al. Large cell neuroendocrine carcinoma: an aggressive form of non-small cell lung cancer. J Thorac Cardiovasc Surg 2005;130:166-172
    • (2005) J Thorac Cardiovasc Surg , vol.130 , pp. 166-172
    • Battafarano, R.J.1    Fernandez, F.G.2    Ritter, J.3
  • 21
    • 33747611697 scopus 로고    scopus 로고
    • Pulmonary neuroendocrine tumors: What (little) do we know?
    • Chen LC, Travis WD, Krug LM. Pulmonary neuroendocrine tumors: what (little) do we know? J Natl Compr Canc Netw 2006;4:623-630
    • (2006) J Natl Compr Canc Netw , vol.4 , pp. 623-630
    • Chen, L.C.1    Travis, W.D.2    Krug, L.M.3
  • 22
    • 84924066485 scopus 로고    scopus 로고
    • Large cell carcinoma of the lung: A tumor in search of an author. A clinically oriented critical reappraisal
    • Pelosi G, Barbareschi M, Cavazza A, Graziano P, Rossi G, Papotti M. Large cell carcinoma of the lung: a tumor in search of an author. A clinically oriented critical reappraisal. Lung Cancer 2015;87:226-231
    • (2015) Lung Cancer , vol.87 , pp. 226-231
    • Pelosi, G.1    Barbareschi, M.2    Cavazza, A.3    Graziano, P.4    Rossi, G.5    Papotti, M.6
  • 23
    • 84873174709 scopus 로고    scopus 로고
    • TrkB/BDNF signaling pathway is a potential therapeutic target for pulmonary large cell neuroendocrine carcinoma
    • Odate S, Nakamura K, Onishi H, et al. TrkB/BDNF signaling pathway is a potential therapeutic target for pulmonary large cell neuroendocrine carcinoma. Lung Cancer 2013;79:205-214
    • (2013) Lung Cancer , vol.79 , pp. 205-214
    • Odate, S.1    Nakamura, K.2    Onishi, H.3
  • 24
    • 75349110215 scopus 로고    scopus 로고
    • Reclassifying bronchial-pulmonary carcinoma: Differentiating histological type in biopsies by immunohistochemistry
    • Carvalho L. Reclassifying bronchial-pulmonary carcinoma: differentiating histological type in biopsies by immunohistochemistry. Rev Port Pneumol 2009;15:1101-1119
    • (2009) Rev Port Pneumol , vol.15 , pp. 1101-1119
    • Carvalho, L.1
  • 25
    • 0033083898 scopus 로고    scopus 로고
    • Genetic changes in the spectrum of neuroendocrine lung tumors
    • Onuki N, Wistuba II, Travis WD, et al. Genetic changes in the spectrum of neuroendocrine lung tumors. Cancer 1999;85:600-607
    • (1999) Cancer , vol.85 , pp. 600-607
    • Onuki, N.1    Wistuba, I.I.2    Travis, W.D.3
  • 26
    • 84890046280 scopus 로고    scopus 로고
    • A genomics-based classification of human lung tumors
    • The Clinical Lung Cancer Genome Project (CLCGP); Network Genomic Medicine (NGM)
    • The Clinical Lung Cancer Genome Project (CLCGP); Network Genomic Medicine (NGM). A genomics-based classification of human lung tumors. Sci Transl Med 2013;5:209-213
    • (2013) Sci Transl Med , vol.5 , pp. 209-213
  • 27
    • 33646248076 scopus 로고    scopus 로고
    • Immunohistochemical differential diagnosis between large cell neuroendocrine carcinoma and small cell carcinoma by tissue microarray analysis with a large antibody panel
    • Nitadori J, Ishii G, Tsuta K, et al. Immunohistochemical differential diagnosis between large cell neuroendocrine carcinoma and small cell carcinoma by tissue microarray analysis with a large antibody panel. Am J Clin Pathol 2006;125:682-692
    • (2006) Am J Clin Pathol , vol.125 , pp. 682-692
    • Nitadori, J.1    Ishii, G.2    Tsuta, K.3
  • 28
    • 67651087283 scopus 로고    scopus 로고
    • Postoperative recurrence and the role of adjuvant chemotherapy in patients with pulmonary large-cell neuroendocrine carcinoma
    • Iyoda A, Hiroshima K, Moriya Y, et al. Postoperative recurrence and the role of adjuvant chemotherapy in patients with pulmonary large-cell neuroendocrine carcinoma. J Thorac Cardiovasc Surg 2009;138:446-453
    • (2009) J Thorac Cardiovasc Surg , vol.138 , pp. 446-453
    • Iyoda, A.1    Hiroshima, K.2    Moriya, Y.3
  • 29
    • 84903788708 scopus 로고    scopus 로고
    • Clinicopathological features and the impact of the new TNM classification of malignant tumors in patients with pulmonary large cell neuroendocrine carcinoma
    • Iyoda A, Jiang SX, Travis WD, et al. Clinicopathological features and the impact of the new TNM classification of malignant tumors in patients with pulmonary large cell neuroendocrine carcinoma. Mol Clin Oncol 2013;1:437-443
    • (2013) Mol Clin Oncol , vol.1 , pp. 437-443
    • Iyoda, A.1    Jiang, S.X.2    Travis, W.D.3
  • 30
    • 0037314948 scopus 로고    scopus 로고
    • Large cell neuroendocrine carcinoma and large cell carcinomas with neuroendocrine morphology of the lung: Prognosis after complete resection and systematic nodal dissection
    • Zacharias J, Nicholson AG, Ladas GP, Goldstraw P. Large cell neuroendocrine carcinoma and large cell carcinomas with neuroendocrine morphology of the lung: prognosis after complete resection and systematic nodal dissection. Ann Thorac Surg 2003;75:348-352
    • (2003) Ann Thorac Surg , vol.75 , pp. 348-352
    • Zacharias, J.1    Nicholson, A.G.2    Ladas, G.P.3    Goldstraw, P.4
  • 31
    • 84881667078 scopus 로고    scopus 로고
    • High grade neuroendocrine lung tumors: Pathological characteristics, surgical management and prognostic implications
    • Grand B, Cazes A, Mordant P, et al. High grade neuroendocrine lung tumors: pathological characteristics, surgical management and prognostic implications. Lung Cancer 2013;81:404-409
    • (2013) Lung Cancer , vol.81 , pp. 404-409
    • Grand, B.1    Cazes, A.2    Mordant, P.3
  • 32
    • 0036753606 scopus 로고    scopus 로고
    • Large cell neuroendocrine carcinoma of the lung: Pathological study and clinical outcome of 18 resected cases
    • Mazires J, Daste G, Molinier L, et al. Large cell neuroendocrine carcinoma of the lung: pathological study and clinical outcome of 18 resected cases. Lung Cancer 2002;37:287-292
    • (2002) Lung Cancer , vol.37 , pp. 287-292
    • Mazires, J.1    Daste, G.2    Molinier, L.3
  • 33
    • 84881660252 scopus 로고    scopus 로고
    • Surgical management of pulmonary large cell neuroendocrine carcinomas: A 10-year experience
    • Fournel L, Falcoz PE, Alifano M, et al. Surgical management of pulmonary large cell neuroendocrine carcinomas: a 10-year experience. Eur J Cardiothorac Surg 2013;43:111-114
    • (2013) Eur J Cardiothorac Surg , vol.43 , pp. 111-114
    • Fournel, L.1    Falcoz, P.E.2    Alifano, M.3
  • 34
    • 74349105477 scopus 로고    scopus 로고
    • Clinical response of large cell neuroendocrine carcinoma of the lung to perioperative adjuvant chemotherapy
    • Saji H, Tsuboi M, Matsubayashi J, et al. Clinical response of large cell neuroendocrine carcinoma of the lung to perioperative adjuvant chemotherapy. Anticancer Drugs 2010;21:89-93
    • (2011) Anticancer Drugs , vol.21 , pp. 89-93
    • Saji, H.1    Tsuboi, M.2    Matsubayashi, J.3
  • 35
    • 33744795445 scopus 로고    scopus 로고
    • Large cell neuroendocrine carcinoma of the lung: A retrospective analysis of 144 surgical cases
    • Veronesi G, Morandi U, Alloisio M, et al. Large cell neuroendocrine carcinoma of the lung: a retrospective analysis of 144 surgical cases. Lung Cancer 2006;53:111-115
    • (2006) Lung Cancer , vol.53 , pp. 111-115
    • Veronesi, G.1    Morandi, U.2    Alloisio, M.3
  • 36
    • 33750087546 scopus 로고    scopus 로고
    • Prospective study of adjuvant chemotherapy for pulmonary large cell neuroendocrine carcinoma
    • Iyoda A, Hiroshima K, Moriya Y, et al. Prospective study of adjuvant chemotherapy for pulmonary large cell neuroendocrine carcinoma. Ann Thorac Surg 2006;82:1802-1807
    • (2006) Ann Thorac Surg , vol.82 , pp. 1802-1807
    • Iyoda, A.1    Hiroshima, K.2    Moriya, Y.3
  • 37
    • 84901953872 scopus 로고    scopus 로고
    • A pilot study of adjuvant chemotherapy with irinotecan and cisplatin for completely resected high-grade pulmonary neuroendocrine carcinoma (large cell neuroendocrine carcinoma and small cell lung cancer
    • Kenmotsu H, Niho S, Ito T, et al. A pilot study of adjuvant chemotherapy with irinotecan and cisplatin for completely resected high-grade pulmonary neuroendocrine carcinoma (large cell neuroendocrine carcinoma and small cell lung cancer). Lung Cancer 2014;84:254-258
    • (2014) Lung Cancer , vol.84 , pp. 254-258
    • Kenmotsu, H.1    Niho, S.2    Ito, T.3
  • 38
    • 84897475114 scopus 로고    scopus 로고
    • A Phase III trial comparing irinotecan and cisplatin with etoposide and cisplatin in adjuvant chemotherapy for completely resected pulmonary high-grade neuroendocrine carcinoma (JCOG1205/1206
    • Lung Cancer Surgical Study Group of the Japan Clinical Oncology Group; Lung Cancer Study Group of the Japan Clinical Oncology Group
    • Eba J, Kenmotsu H, Tsuboi M, et al; Lung Cancer Surgical Study Group of the Japan Clinical Oncology Group; Lung Cancer Study Group of the Japan Clinical Oncology Group. A Phase III trial comparing irinotecan and cisplatin with etoposide and cisplatin in adjuvant chemotherapy for completely resected pulmonary high-grade neuroendocrine carcinoma (JCOG1205/1206). Jpn J Clin Oncol 2014;44:379-382
    • (2014) Jpn J Clin Oncol , vol.44 , pp. 379-382
    • Eba, J.1    Kenmotsu, H.2    Tsuboi, M.3
  • 39
    • 77950996012 scopus 로고    scopus 로고
    • ERCC1 and Ki67 in small cell lung carcinoma and other neuroendocrine tumors of the lung: Distribution and impact on survival
    • Skov BG, Holm B, Erreboe A, Skov T, Mellemgaard A. ERCC1 and Ki67 in small cell lung carcinoma and other neuroendocrine tumors of the lung: distribution and impact on survival. J Thorac Oncol 2010;5:453-459
    • (2011) J Thorac Oncol , vol.5 , pp. 453-459
    • Skov, B.G.1    Holm, B.2    Erreboe, A.3    Skov, T.4    Mellemgaard, A.5
  • 40
    • 80053310940 scopus 로고    scopus 로고
    • Neoadjuvant and adjuvant chemotherapy in resected pulmonary large cell neuroendocrine carcinomas: A single institution experience
    • Sarkaria IS, Iyoda A, Roh MS, et al. Neoadjuvant and adjuvant chemotherapy in resected pulmonary large cell neuroendocrine carcinomas: a single institution experience. Ann Thorac Surg 2011;92:1180-1186
    • (2011) Ann Thorac Surg , vol.92 , pp. 1180-1186
    • Sarkaria, I.S.1    Iyoda, A.2    Roh, M.S.3
  • 41
    • 84942902185 scopus 로고    scopus 로고
    • Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFR β, PDGFR α, and Met in large-cell neuroendocrine carcinoma of the lung
    • Rossi G, Cavazza A, Marchioni A, et al. Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFR β, PDGFR α, and Met in large-cell neuroendocrine carcinoma of the lung. J Clin Oncol 2006;34:8775-8785
    • (2006) J Clin Oncol , vol.34 , pp. 8775-8785
    • Rossi, G.1    Cavazza, A.2    Marchioni, A.3
  • 42
    • 34548344037 scopus 로고    scopus 로고
    • Effect of platinum combined with irinotecan or paclitaxel against large cell neuroendocrine carcinoma of the lung
    • Fujiwara Y, Sekine I, Tsuta K, et al. Effect of platinum combined with irinotecan or paclitaxel against large cell neuroendocrine carcinoma of the lung. Jpn J Clin Oncol 2007;37:482-486
    • (2007) Jpn J Clin Oncol , vol.37 , pp. 482-486
    • Fujiwara, Y.1    Sekine, I.2    Tsuta, K.3
  • 43
    • 0033950286 scopus 로고    scopus 로고
    • Comparison of survival and quality of life in advanced non-small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: Results of an Eastern Cooperative Oncology Group trial
    • Bonomi P, Kim K, Fairclough D, et al. Comparison of survival and quality of life in advanced non-small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: results of an Eastern Cooperative Oncology Group trial. J Clin Oncol 2000;18:623-631
    • (2000) J Clin Oncol , vol.18 , pp. 623-631
    • Bonomi, P.1    Kim, K.2    Fairclough, D.3
  • 44
    • 0037050354 scopus 로고    scopus 로고
    • Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer
    • Japan Clinical Oncology Group
    • Noda K, Nishiwaki Y, Kawahara M, et al; Japan Clinical Oncology Group. Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer. N Engl J Med 2002;346:85-91
    • (2002) N Engl J Med , vol.346 , pp. 85-91
    • Noda, K.1    Nishiwaki, Y.2    Kawahara, M.3
  • 45
    • 1342332364 scopus 로고    scopus 로고
    • Phase III randomized trial of docetaxel plus cisplatin versus vindesine plus cisplatin in patients with stage IV non-small-cell lung cancer: The Japanese Taxotere Lung Cancer Study Group
    • Japanese Taxotere Lung Cancer Study Group
    • Kubota K, Watanabe K, Kunitoh H, et al; Japanese Taxotere Lung Cancer Study Group. Phase III randomized trial of docetaxel plus cisplatin versus vindesine plus cisplatin in patients with stage IV non-small-cell lung cancer: the Japanese Taxotere Lung Cancer Study Group. J Clin Oncol 2004;22:254-261
    • (2004) J Clin Oncol , vol.22 , pp. 254-261
    • Kubota, K.1    Watanabe, K.2    Kunitoh, H.3
  • 46
    • 77952546398 scopus 로고    scopus 로고
    • Comparison of chemotherapy for unresectable pulmonary high-grade non-small cell neuroendocrine carcinoma and small-cell lung cancer
    • Igawa S, Watanabe R, Ito I, et al. Comparison of chemotherapy for unresectable pulmonary high-grade non-small cell neuroendocrine carcinoma and small-cell lung cancer. Lung Cancer 2010;68:438-445
    • (2011) Lung Cancer , vol.68 , pp. 438-445
    • Igawa, S.1    Watanabe, R.2    Ito, I.3
  • 47
    • 79551563284 scopus 로고    scopus 로고
    • International association for the study of lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma
    • Travis WD, Brambilla E, Noguchi M, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma. J Thorac Oncol 2011;6:244-285
    • (2011) J Thorac Oncol , vol.6 , pp. 244-285
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3
  • 48
    • 84894573383 scopus 로고    scopus 로고
    • Comparison of chemotherapeutic efficacy between LCNEC diagnosed using large specimens and possible LCNEC diagnosed using small biopsy specimens
    • Tokito T, Kenmotsu H, Watanabe R, et al. Comparison of chemotherapeutic efficacy between LCNEC diagnosed using large specimens and possible LCNEC diagnosed using small biopsy specimens. Int J Clin Oncol 2014;19:63-67
    • (2014) Int J Clin Oncol , vol.19 , pp. 63-67
    • Tokito, T.1    Kenmotsu, H.2    Watanabe, R.3
  • 49
    • 84856574541 scopus 로고    scopus 로고
    • Clinical features of unresectable highgrade lung neuroendocrine carcinoma diagnosed using biopsy specimens
    • Shimada Y, Niho S, Ishii G, et al. Clinical features of unresectable highgrade lung neuroendocrine carcinoma diagnosed using biopsy specimens. Lung Cancer 2012;75:368-373
    • (2012) Lung Cancer , vol.75 , pp. 368-373
    • Shimada, Y.1    Niho, S.2    Ishii, G.3
  • 50
    • 84863779805 scopus 로고    scopus 로고
    • Chemotherapy for pulmonary large cell neuroendocrine carcinoma: Similar to that for small cell lung cancer or non-small cell lung cancer?
    • Sun JM, Ahn MJ, Ahn JS, et al. Chemotherapy for pulmonary large cell neuroendocrine carcinoma: similar to that for small cell lung cancer or non-small cell lung cancer? Lung Cancer 2012;77:365-370
    • (2012) Lung Cancer , vol.77 , pp. 365-370
    • Sun, J.M.1    Ahn, M.J.2    Ahn, J.S.3
  • 51
    • 73349084270 scopus 로고    scopus 로고
    • Differential thymidylate synthase expression in different variants of large-cell carcinoma of the lung
    • Monica V, Scagliotti GV, Ceppi P, et al. Differential thymidylate synthase expression in different variants of large-cell carcinoma of the lung. Clin Cancer Res 2009;15:7547-7552
    • (2009) Clin Cancer Res , vol.15 , pp. 7547-7552
    • Monica, V.1    Scagliotti, G.V.2    Ceppi, P.3
  • 52
    • 61549083739 scopus 로고    scopus 로고
    • Pemetrexed in second line and beyond small cell lung cancer: A Hoosier Oncology Group phase II study
    • Jalal S, Ansari R, Govindan R, et al. Pemetrexed in second line and beyond small cell lung cancer: a Hoosier Oncology Group phase II study. J Thorac Oncol 2009;4:93-96
    • (2009) J Thorac Oncol , vol.4 , pp. 93-96
    • Jalal, S.1    Ansari, R.2    Govindan, R.3
  • 53
    • 2442661845 scopus 로고    scopus 로고
    • Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
    • Hanna N, Shepherd FA, Fossella FV, et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 2004;22:1589-1597
    • (2004) J Clin Oncol , vol.22 , pp. 1589-1597
    • Hanna, N.1    Shepherd, F.A.2    Fossella, F.V.3
  • 54
    • 33644770041 scopus 로고    scopus 로고
    • Gefitinib in patients with chemosensitive and chemo-refractory relapsed small cell cancers: A Hoosier Oncology Group phase II trial
    • Moore AM, Einhorn LH, Estes D, et al. Gefitinib in patients with chemosensitive and chemo-refractory relapsed small cell cancers: a Hoosier Oncology Group phase II trial. Lung Cancer 2006;52:93-97
    • (2006) Lung Cancer , vol.52 , pp. 93-97
    • Moore, A.M.1    Einhorn, L.H.2    Estes, D.3
  • 55
    • 84878430396 scopus 로고    scopus 로고
    • Multicentre phase II study of cisplatin-etoposide chemotherapy for advanced large-cell neuroendocrine lung carcinoma: The GFPC 0302 study
    • Le Treut J, Sault MC, Lena H, et al. Multicentre phase II study of cisplatin-etoposide chemotherapy for advanced large-cell neuroendocrine lung carcinoma: the GFPC 0302 study. Ann Oncol 2013;24:1548-1552
    • (2013) Ann Oncol , vol.24 , pp. 1548-1552
    • Le Treut, J.1    Sault, M.C.2    Lena, H.3
  • 56
    • 84880892037 scopus 로고    scopus 로고
    • Combination chemotherapy with irinotecan and cisplatin for large-cell neuroendocrine carcinoma of the lung: A multicenter phase II study
    • Niho S, Kenmotsu H, Sekine I, et al. Combination chemotherapy with irinotecan and cisplatin for large-cell neuroendocrine carcinoma of the lung: a multicenter phase II study. J Thorac Oncol 2013;8:980-984
    • (2013) J Thorac Oncol , vol.8 , pp. 980-984
    • Niho, S.1    Kenmotsu, H.2    Sekine, I.3
  • 57
    • 84904796605 scopus 로고    scopus 로고
    • Phase III study comparing amrubicin plus cisplatin with irinotecan plus cisplatin in the treatment of extensive-disease small-cell lung cancer: JCOG 0509
    • Satouchi M, Kotani Y, Shibata T, et al. Phase III study comparing amrubicin plus cisplatin with irinotecan plus cisplatin in the treatment of extensive-disease small-cell lung cancer: JCOG 0509. J Clin Oncol 2014;32:1262-1268
    • (2014) J Clin Oncol , vol.32 , pp. 1262-1268
    • Satouchi, M.1    Kotani, Y.2    Shibata, T.3
  • 58
    • 79960074875 scopus 로고    scopus 로고
    • Amrubicin monotherapy for patients with previously treated advanced large-cell neuroendocrine carcinoma of the lung
    • Yoshida H, Sekine I, Tsuta K, et al. Amrubicin monotherapy for patients with previously treated advanced large-cell neuroendocrine carcinoma of the lung. Jpn J Clin Oncol 2011;41:897-901
    • (2011) Jpn J Clin Oncol , vol.41 , pp. 897-901
    • Yoshida, H.1    Sekine, I.2    Tsuta, K.3
  • 59
    • 84877041134 scopus 로고    scopus 로고
    • A phase II study of amrubicin as a third-line or fourth-line chemotherapy for patients with non-small cell lung cancer: Hokkaido Lung Cancer Clinical Study Group Trial (HOT) 0901
    • Hokkaido Lung Cancer Clinical Study Group
    • Harada T, Oizumi S, Ito K, et al; Hokkaido Lung Cancer Clinical Study Group. A phase II study of amrubicin as a third-line or fourth-line chemotherapy for patients with non-small cell lung cancer: Hokkaido Lung Cancer Clinical Study Group Trial (HOT) 0901. Oncologist 2013;18:439-445
    • (2013) Oncologist , vol.18 , pp. 439-445
    • Harada, T.1    Oizumi, S.2    Ito, K.3
  • 60
    • 84883437507 scopus 로고    scopus 로고
    • Large-cell neuroendocrine carcinoma of lung with epidermal growth factor receptor (EGFR) gene mutation and co-expression of adenocarcinoma markers: A case report and review of the literature
    • Sakai Y, Yamasaki T, Kusakabe Y, et al. Large-cell neuroendocrine carcinoma of lung with epidermal growth factor receptor (EGFR) gene mutation and co-expression of adenocarcinoma markers: a case report and review of the literature. Multidiscip Respir Med 2013;8:47-53
    • (2013) Multidiscip Respir Med , vol.8 , pp. 47-53
    • Sakai, Y.1    Yamasaki, T.2    Kusakabe, Y.3
  • 61
    • 80052694910 scopus 로고    scopus 로고
    • Expression profiling and identification of potential molecular targets for therapy in pulmonary large-cell neuroendocrine carcinoma
    • Iyoda A, Travis WD, Sarkaria IS, et al. Expression profiling and identification of potential molecular targets for therapy in pulmonary large-cell neuroendocrine carcinoma. Exp Ther Med 2011;2:1041-1045
    • (2011) Exp Ther Med , vol.2 , pp. 1041-1045
    • Iyoda, A.1    Travis, W.D.2    Sarkaria, I.S.3
  • 62
    • 83255164853 scopus 로고    scopus 로고
    • Large-cell neuroendocrine carcinoma of the lung harboring EGFR mutation and responding to gefitinib
    • De Pas TM, Giovannini M, Manzotti M, et al. Large-cell neuroendocrine carcinoma of the lung harboring EGFR mutation and responding to gefitinib. J Clin Oncol 2011;29:e819-e822
    • (2011) J Clin Oncol , vol.29 , pp. e819-e822
    • De Pas, T.M.1    Giovannini, M.2    Manzotti, M.3
  • 63
    • 84867968006 scopus 로고    scopus 로고
    • Large-cell neuroendocrine carcinoma with EGFR mutation: Possible transformation of lung adenocarcinoma
    • Yanagisawa S, Morikawa N, Kimura Y, et al. Large-cell neuroendocrine carcinoma with EGFR mutation: possible transformation of lung adenocarcinoma. Respirology 2012;17:1275-1277
    • (2012) Respirology , vol.17 , pp. 1275-1277
    • Yanagisawa, S.1    Morikawa, N.2    Kimura, Y.3
  • 64
    • 84898903594 scopus 로고    scopus 로고
    • Angiogenesis in cancer-general pathways and their therapeutic implications
    • Dimova I, Popivanov G, Djonov V. Angiogenesis in cancer-general pathways and their therapeutic implications. J BUON 2014;19:15-21
    • (2014) J BUON , vol.19 , pp. 15-21
    • Dimova, I.1    Popivanov, G.2    Djonov, V.3
  • 65
    • 84902521061 scopus 로고    scopus 로고
    • Activation of angiogenesis differs strongly between pulmonary carcinoids and neuroendocrine carcinomas and is crucial for carcinoid tumorigenesis
    • Mairinger FD, Walter RF, Werner R, et al. Activation of angiogenesis differs strongly between pulmonary carcinoids and neuroendocrine carcinomas and is crucial for carcinoid tumorigenesis. J Cancer 2014;5:465-471
    • (2014) J Cancer , vol.5 , pp. 465-471
    • Mairinger, F.D.1    Walter, R.F.2    Werner, R.3
  • 66
    • 84893414384 scopus 로고    scopus 로고
    • Clinical implications of VEGF, TGF-β1, and IL-1β in patients with advanced non-small cell lung cancer
    • Kim JW, Koh Y, Kim DW, et al. Clinical implications of VEGF, TGF-β1, and IL-1β in patients with advanced non-small cell lung cancer. Cancer Res Treat 2013;45:325-333
    • (2013) Cancer Res Treat , vol.45 , pp. 325-333
    • Kim, J.W.1    Koh, Y.2    Kim, D.W.3
  • 67
    • 84894255633 scopus 로고    scopus 로고
    • Polymorphisms of HIF1A gene are associated with prognosis of early stage non-small-cell lung cancer patients after surgery
    • Liu B, Liu Q, Song Y, et al. Polymorphisms of HIF1A gene are associated with prognosis of early stage non-small-cell lung cancer patients after surgery. Med Oncol 2014;31:877-886
    • (2014) Med Oncol , vol.31 , pp. 877-886
    • Liu, B.1    Liu, Q.2    Song, Y.3
  • 68
    • 84859967949 scopus 로고    scopus 로고
    • Nedaplatin and irinotecan in patients with large-cell neuroendocrine carcinoma of the lung
    • Kenmotsu Y, Oshita F, Sugiura M, et al. Nedaplatin and irinotecan in patients with large-cell neuroendocrine carcinoma of the lung. Anticancer Res 2012;32:1453-1456
    • (2012) Anticancer Res , vol.32 , pp. 1453-1456
    • Kenmotsu, Y.1    Oshita, F.2    Sugiura, M.3
  • 69
    • 0029983299 scopus 로고    scopus 로고
    • Analysis of p53, K-ras-2, and C-raf-1 in pulmonary neuroendocrine tumors. Correlation with histological subtype and clinical outcome
    • Przygodzki RM, Finkelstein SD, Langer JC, et al. Analysis of p53, K-ras-2, and C-raf-1 in pulmonary neuroendocrine tumors. Correlation with histological subtype and clinical outcome. Am J Pathol 1996;148:1531-1541
    • (1996) Am J Pathol , vol.148 , pp. 1531-1541
    • Przygodzki, R.M.1    Finkelstein, S.D.2    Langer, J.C.3
  • 70
    • 1542374046 scopus 로고    scopus 로고
    • Genetic alterations in earlystage pulmonary large cell neuroendocrine carcinoma
    • Hiroshima K, Iyoda A, Shibuya K, et al. Genetic alterations in earlystage pulmonary large cell neuroendocrine carcinoma. Cancer 2004;100:1190-1198
    • (2004) Cancer , vol.100 , pp. 1190-1198
    • Hiroshima, K.1    Iyoda, A.2    Shibuya, K.3
  • 71
    • 16844377089 scopus 로고    scopus 로고
    • Large-cell neuroendocrine carcinoma of the lung: A clinicopathologic study of eighteen cases and the efficacy of adjuvant treatment with octreotide
    • Filosso PL, Ruffini E, Oliaro A, et al. Large-cell neuroendocrine carcinoma of the lung: a clinicopathologic study of eighteen cases and the efficacy of adjuvant treatment with octreotide. J Thorac Cardiovasc Surg 2005;129:819-824
    • (2005) J Thorac Cardiovasc Surg , vol.129 , pp. 819-824
    • Filosso, P.L.1    Ruffini, E.2    Oliaro, A.3
  • 72
    • 22044450203 scopus 로고    scopus 로고
    • Clinical responses of large cell neuroendocrine carcinoma of the lung to cisplatin-based chemotherapy
    • Yamazaki S, Sekine I, Matsuno Y, et al. Clinical responses of large cell neuroendocrine carcinoma of the lung to cisplatin-based chemotherapy. Lung Cancer 2005;49:217-223
    • (2005) Lung Cancer , vol.49 , pp. 217-223
    • Yamazaki, S.1    Sekine, I.2    Matsuno, Y.3
  • 73
    • 84925883603 scopus 로고    scopus 로고
    • Prophylactic cranial irradiation: Recent outcomes and innovations
    • Snider JW, Gondi V, Brown PD, Tome W, Mehta MP. Prophylactic cranial irradiation: recent outcomes and innovations. CNS Oncol 2014;3:219-230
    • (2014) CNS Oncol , vol.3 , pp. 219-230
    • Snider, J.W.1    Gondi, V.2    Brown, P.D.3    Tome, W.4    Mehta, M.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.