Impact of carbapenem resistance on epidemiology and outcomes of nonbacteremic Klebsiella pneumoniae infections This work was presented in part at the Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington, DC, September 7, 2014 (poster K-1026).

American Journal of Infection Control

Volumn 43, Issue 10, 2015, Pages 1076-1080

  Ny, Pamela ^a   Nieberg, Paul ^a   Wong Beringer, Annie ^a,b  

^a HUNTINGTON MEMORIAL HOSPITAL   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Carbapenem resistant Klebsiella pneumoniae; Nonbacteremia

Indexed keywords

ANTIBIOTIC AGENT; CARBAPENEM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; ANTIINFECTIVE AGENT; CARBAPENEM DERIVATIVE;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; APACHE; ARTICLE; CARBAPENEM RESISTANT ENTEROBACTERIACEAE; CASE CONTROL STUDY; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DECUBITUS; DEMOGRAPHY; FEMALE; HEALTH CARE COST; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITAL PATIENT; HOSPITAL READMISSION; HUMAN; INFECTION CONTROL; INFECTION RISK; INTENSIVE CARE UNIT; KLEBSIELLA PNEUMONIAE INFECTION; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MIXED INFECTION; NURSING HOME; RETROSPECTIVE STUDY; TRACHEOSTOMY; TREATMENT OUTCOME; URINARY TRACT INFECTION; ADOLESCENT; DRUG EFFECTS; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICROBIOLOGY; MIDDLE AGED; PNEUMONIA, BACTERIAL; RISK FACTOR; URINARY TRACT INFECTIONS; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; CARBAPENEMS; FEMALE; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MIDDLE AGED; PNEUMONIA, BACTERIAL; RETROSPECTIVE STUDIES; RISK FACTORS; TREATMENT OUTCOME; URINARY TRACT INFECTIONS; YOUNG ADULT;

EID: 84942923979     PISSN: 01966553     EISSN: 15273296     Source Type: Journal    
DOI: 10.1016/j.ajic.2015.06.008     Document Type: Article

References (28)

1. L.S. Tzouvelekis, A. Markogiannakis, M. Psichogiou, P.T. Tassios, and G.L. Daikos Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions Clin Microbiol Rev 25 2012 682 707
2. P. Marquez, D. Terashita, D. Dassey, and L. Mascola Population-based incidence of carbapenem-resistant Klebsiella pneumoniae along the continuum of care, Los Angeles County Infect Control Hosp Epidemiol 34 2013 144 150
3. D. Ben-David, S. Masarwa, S. Navon-Venezia, H. Mishali, I. Fridental, B. Rubinovitch, and et al. Carbapenem-resistant Klebsiella pneumoniae in post-acute care facilities in Israel Infect Control Hosp Epidemiol 32 2011 845 853
4. M.N. Balm, M.V. La, P. Krishnan, R. Jureen, R.T. Lin, and J.W. Teo Emergence of Klebsiella pneumoniae co-producing NDM-type and OXA-181 carbapenemases Clin Microbiol Infect 19 2013 E421 E423
5. P. Marquez, and D. Terashita Editorial commentary: long-term acute care hospitals and carbapenem-resistant Enterobacteriaceae: a reservoir for transmission Clin Infect Dis 57 2013 1253 1255
6. A. Endimiani, J.M. Depasquale, S. Forero, F. Perez, A.M. Hujer, D. Roberts-Pollack, and et al. Emergence of blaKPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system J Antimicrob Chemother 64 2009 1102 1110
7. M. McGuinn, R.C. Hershow, and W.M. Janda Escherichia coli and Klebsiella pneumoniae carbapenemase in a long-term care facility, Illinois, USA Emerg Infect Dis 15 2009 988 989
8. C. Urban, P.A. Bradford, M. Tuckman, S. Segal-Maurer, W. Wehbeh, L. Grenner, and et al. Carbapenem-resistant Escherichia coli harboring Klebsiella pneumoniae carbapenemase beta-lactamases associated with long-term care facilities Clin Infect Dis 46 2008 e127 e130
9. M.J. Schwaber, S. Klarfeld-Lidji, S. Navon-Venezia, D. Schwartz, A. Leavitt, and Y. Carmeli Predictors of carbapenem-resistant Klebsiella pneumoniae acquisition among hospitalized adults and effect of acquisition on mortality Antimicrobial Agents Chemother 52 2008 1028 1033
10. N. Kassis-Chikhani, F. Saliba, A. Carbonne, S. Neuville, D. Decre, C. Sengelin, and et al. Extended measures for controlling an outbreak of VIM-1 producing imipenem-resistant Klebsiella pneumoniae in a liver transplant centre in France, 2003-2004 Euro Surveill 15 2010 19713
11. G. Patel, F. Perez, and R.A. Bonomo Carbapenem-resistant Enterobacteriaceae and Acinetobacter baumannii: assessing their impact on organ transplantation Curr Opin Organ Transplant 15 2010 676 682
12. D. Marchaim, S. Navon-Venezia, M.J. Schwaber, and Y. Carmeli Isolation of imipenem-resistant Enterobacter species: emergence of KPC-2 carbapenemase, molecular characterization, epidemiology, and outcomes Antimicrobial Agents Chemother 52 2008 1413 1418
13. C.J. Gregory, E. Llata, N. Stine, C. Gould, L.M. Santiago, G.J. Vazquez, and et al. Outbreak of carbapenem-resistant Klebsiella pneumoniae in Puerto Rico associated with a novel carbapenemase variant Infect Control Hosp Epidemiol 31 2010 476 484
14. G.L. Daikos, E. Vryonis, M. Psichogiou, L.S. Tzouvelekis, S. Liatis, P. Petrikkos, and et al. Risk factors for bloodstream infection with Klebsiella pneumoniae producing VIM-1 metallo-beta-lactamase J Antimicrob Chemother 65 2010 784 788
15. N. Patel, S. Harrington, A. Dihmess, B. Woo, R. Masoud, P. Martis, and et al. Clinical epidemiology of carbapenem-intermediate or -resistant Enterobacteriaceae J Antimicrob Chemother 66 2011 1600 1608
16. E.A. Neuner, J.Y. Yeh, G.S. Hall, J. Sekeres, A. Endimiani, R.A. Bonomo, and et al. Treatment and outcomes in carbapenem-resistant Klebsiella pneumoniae bloodstream infections Diagn Microbiol Infect Dis 69 2011 357 362
17. L. Correa, M.D. Martino, I. Siqueira, J. Pasternak, A.C. Gales, C.V. Silva, and et al. A hospital-based matched case-control study to identify clinical outcome and risk factors associated with carbapenem-resistant Klebsiella pneumoniae infection BMC Infect Dis 13 2013 80
18. L.B. Gasink, P.H. Edelstein, E. Lautenbach, M. Synnestvedt, and N.O. Fishman Risk factors and clinical impact of Klebsiella pneumoniae carbapenemase-producing K pneumoniae Infect Control Hosp Epidemiol 30 2009 1180 1185
19. G. Patel, S. Huprikar, S.H. Factor, S.G. Jenkins, and D.P. Calfee Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies Infect Control Hosp Epidemiol 29 2008 1099 1106
20. P.A. Harris, R. Taylor, R. Thielke, J. Payne, N. Gonzalez, and J.G. Conde Research electronic data capture (REDCap): a metadata-driven methodology and workflow process for providing translational research informatics support J Biomed Inform 42 2009 377 381
21. A. Elixhauser, C. Steiner, D.R. Harris, and R.M. Coffey Comorbidity measures for use with administrative data Med Care 36 1998 8 27
22. M.E. Falagas, P.I. Rafailidis, D. Kofteridis, S. Virtzili, F.C. Chelvatzoglou, V. Papaioannou, and et al. Risk factors of carbapenem-resistant Klebsiella pneumoniae infections: a matched case-control study J Antimicrob Chemother 60 2007 1124 1130
23. Y.G. Kwak, S.H. Choi, E.J. Choo, J.W. Chung, J.Y. Jeong, N.J. Kim, and et al. Risk factors for the acquisition of carbapenem-resistant Klebsiella pneumoniae among hospitalized patients Microb Drug Resist 11 2005 165 169
24. M.Y. Lin, R.D. Lyles-Banks, K. Lolans, D.W. Hines, J.B. Spear, R. Petrak, and et al. The importance of long-term acute care hospitals in the regional epidemiology of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae Clin Infect Dis 57 2013 1246 1252
25. A.M. Queenan, and K. Bush Carbapenemases: the versatile beta-lactamases Clin Microbiol Rev 20 2007 440 458
26. T.D. Gootz, M.K. Lescoe, F. Dib-Hajj, B.A. Dougherty, W. He, P. Della-Latta, and et al. Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital Antimicrobial Agents Chemother 53 2009 1998 2004
27. T. Naas, G. Cuzon, M.V. Villegas, M.F. Lartigue, J.P. Quinn, and P. Nordmann Genetic structures at the origin of acquisition of the beta-lactamase bla KPC gene Antimicrobial Agents Chemother 52 2008 1257 1263
28. R.M. Klevens, J.R. Edwards, C.L. Richards Jr., T.C. Horan, R.P. Gaynes, D.A. Pollock, and et al. Estimating health care-associated infections and deaths in US hospitals, 2002 Public Health Rep 122 2007 160 166