Platelet activation and thrombus formation over IgG immune complexes requires integrin aIIbβ3 and lyn kinase

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Zhi, Huiying ^a   Dai, Jing ^b   Liu, Junling ^b   Zhu, Jieqing ^a,c   Newman, Debra K ^a,c   Gao, Cunji ^a,d   Newman, Peter J ^a,c  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAIIB BETA3 INTEGRIN; FC RECEPTOR IIA; FIBRINOGEN; PROTEIN KINASE LYN; PROTEIN KINASE SYK; THROMBOCYTE FACTOR 4; THROMBOCYTE RECEPTOR; UNCLASSIFIED DRUG; ADHESION RECEPTOR; ANTIGEN ANTIBODY COMPLEX; FC RECEPTOR; FIBRINOGEN RECEPTOR; IMMUNOGLOBULIN G; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE; THROMBIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL SPREADING; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IMMUNE COMPLEX DISEASE; IN VITRO STUDY; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOSIS; ANIMAL; ANTIGEN ANTIBODY COMPLEX; AUTOIMMUNE DISEASE; C57BL MOUSE; CELL LINE; CHO CELL LINE; CRICETULUS; HUMAN; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; THROMBOCYTE; THROMBOCYTE AGGREGATION;

ANIMALS; ANTIGEN-ANTIBODY COMPLEX; AUTOIMMUNE DISEASES; BLOOD PLATELETS; CELL LINE; CHO CELLS; CRICETULUS; FIBRINOGEN; HUMANS; IMMUNOGLOBULIN G; MICE; MICE, INBRED C57BL; PLATELET ACTIVATION; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN-TYROSINE KINASES; RECEPTORS, IGG; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; THROMBOSIS;

EID: 84942901879     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0135738     Document Type: Article

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