메뉴 건너뛰기




Volumn 59, Issue 10, 2015, Pages 6615-6619

A novel Y319H substitution in CYP51C associated with azole resistance in Aspergillus flavus

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANIDULAFUNGIN; CASPOFUNGIN; ECHINOCANDIN; ITRACONAZOLE; MICAFUNGIN; POSACONAZOLE; PYRROLE; STEROL 14ALPHA DEMETHYLASE; STEROL 14ALPHA DEMETHYLASE C; UNCLASSIFIED DRUG; VORICONAZOLE; FUNGAL PROTEIN; PYRROLE DERIVATIVE;

EID: 84942900657     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00637-15     Document Type: Article
Times cited : (57)

References (28)
  • 1
    • 67651096196 scopus 로고    scopus 로고
    • Differences in pathogenicity and clinical syndromes due to Aspergillus fumigatus and Aspergillus flavus
    • Pasqualotto AC. 2009. Differences in pathogenicity and clinical syndromes due to Aspergillus fumigatus and Aspergillus flavus. Med Mycol 47(Suppl 1):S261-S270.
    • (2009) Med Mycol , vol.47 , pp. S261-S270
    • Pasqualotto, A.C.1
  • 2
    • 34250783965 scopus 로고    scopus 로고
    • Aspergillus flavus: Human pathogen, allergen and mycotoxin producer
    • Hedayati MT, Pasqualotto AC, Warn PA, Bowyer P, Denning DW. 2007. Aspergillus flavus: human pathogen, allergen and mycotoxin producer. Microbiology 153:1677-1692. http://dx.doi.org/10.1099/mic.0.2007/007641-0.
    • (2007) Microbiology , vol.153 , pp. 1677-1692
    • Hedayati, M.T.1    Pasqualotto, A.C.2    Warn, P.A.3    Bowyer, P.4    Denning, D.W.5
  • 3
    • 63849275754 scopus 로고    scopus 로고
    • Aspergillus flavus: An emerging non-fumigatus Aspergillus species of significance
    • Krishnan S, Manavathu EK, Chandrasekar PH. 2009. Aspergillus flavus: an emerging non-fumigatus Aspergillus species of significance. Mycoses 52:206-222. http://dx.doi.org/10.1111/j.1439-0507.2008.01642.x.
    • (2009) Mycoses , vol.52 , pp. 206-222
    • Krishnan, S.1    Manavathu, E.K.2    Chandrasekar, P.H.3
  • 4
  • 5
    • 84937636784 scopus 로고    scopus 로고
    • Epidemiology of chronic fungal rhinosinusitis in rural India
    • Chakrabarti A, Rudramurthy SM, Panda N, Das A, Singh A. 2015. Epidemiology of chronic fungal rhinosinusitis in rural India. Mycoses 58:294-302. http://dx.doi.org/10.1111/myc.12314.
    • (2015) Mycoses , vol.58 , pp. 294-302
    • Chakrabarti, A.1    Rudramurthy, S.M.2    Panda, N.3    Das, A.4    Singh, A.5
  • 6
    • 80055000208 scopus 로고    scopus 로고
    • The emerging epidemiology of mould infections in developing countries
    • Chakrabarti A, Singh R. 2011. The emerging epidemiology of mould infections in developing countries. Curr Opin Infect Dis 24:521-526. http://dx.doi.org/10.1097/QCO.0b013e32834ab21e.
    • (2011) Curr Opin Infect Dis , vol.24 , pp. 521-526
    • Chakrabarti, A.1    Singh, R.2
  • 8
    • 33845934777 scopus 로고    scopus 로고
    • Cerebral aspergillosis diagnosed by detection of Aspergillus flavus-specific DNA, galactomannan and (1→3)-beta-D-glucan in clinical specimens
    • Khan ZU, Ahmad S, Mokaddas E, Said T, Nair MP, Halim MA, Nampoory MR, McGinnis MR. 2007. Cerebral aspergillosis diagnosed by detection of Aspergillus flavus-specific DNA, galactomannan and (1→3)-beta-D-glucan in clinical specimens. J Med Microbiol 56:129-132. http://dx.doi.org/10.1099/jmm.0.46549-0.
    • (2007) J Med Microbiol , vol.56 , pp. 129-132
    • Khan, Z.U.1    Ahmad, S.2    Mokaddas, E.3    Said, T.4    Nair, M.P.5    Halim, M.A.6    Nampoory, M.R.7    McGinnis, M.R.8
  • 9
    • 71549143158 scopus 로고    scopus 로고
    • Azole resistance in Aspergillus fumigatus: A side-effect of environmental fungicide use?
    • Verweij PE, Snelders E, Kema GH, Mellado E, Melchers WJ. 2009. Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use? Lancet Infect Dis 9:789-795. http://dx.doi.org/10.1016/S1473-3099(09)70265-8.
    • (2009) Lancet Infect Dis , vol.9 , pp. 789-795
    • Verweij, P.E.1    Snelders, E.2    Kema, G.H.3    Mellado, E.4    Melchers, W.J.5
  • 10
    • 84885930731 scopus 로고    scopus 로고
    • Emergence of azoleresistant Aspergillus fumigatus strains due to agricultural azole use creates an increasing threat to human health
    • Chowdhary A, Kathuria S, Xu J, Meis JF. 2013. Emergence of azoleresistant Aspergillus fumigatus strains due to agricultural azole use creates an increasing threat to human health. PLoS Pathog 9:e1003633. http://dx.doi.org/10.1371/journal.ppat.1003633.
    • (2013) PLoS Pathog , vol.9 , pp. e1003633
    • Chowdhary, A.1    Kathuria, S.2    Xu, J.3    Meis, J.F.4
  • 11
    • 84855860621 scopus 로고    scopus 로고
    • Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India
    • Chowdhary A, Kathuria S, Randhawa HS, Gaur SN, Klaassen CH, Meis JF. 2012. Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India. J Antimicrob Chemother 67:362-366. http://dx.doi.org/10.1093/jac/dkr443.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 362-366
    • Chowdhary, A.1    Kathuria, S.2    Randhawa, H.S.3    Gaur, S.N.4    Klaassen, C.H.5    Meis, J.F.6
  • 13
    • 55249114346 scopus 로고    scopus 로고
    • Molecular characterisation of CYP51A and CYP51B genes coding for P450 14alpha-lanosterol demethylases A (CYP51Ap) and B (CYP51Bp) from voriconazole-resistant laboratory isolates of Aspergillus flavus
    • Krishnan-Natesan S, Chandrasekar PH, Alangaden GJ, Manavathu EK. 2008. Molecular characterisation of CYP51A and CYP51B genes coding for P450 14alpha-lanosterol demethylases A (CYP51Ap) and B (CYP51Bp) from voriconazole-resistant laboratory isolates of Aspergillus flavus. Int J Antimicrob Agents 32:519-524. http://dx.doi.org/10.1016/j.ijantimicag.2008.06.018.
    • (2008) Int J Antimicrob Agents , vol.32 , pp. 519-524
    • Krishnan-Natesan, S.1    Chandrasekar, P.H.2    Alangaden, G.J.3    Manavathu, E.K.4
  • 14
    • 84880716413 scopus 로고    scopus 로고
    • Differential expression of ATP-binding cassette and/or major facilitator superfamily class efflux pumps contributes to voriconazole resistance in Aspergillus flavus
    • Natesan SK, Lamichchane AK, Swaminathan S, Wu W. 2013. Differential expression of ATP-binding cassette and/or major facilitator superfamily class efflux pumps contributes to voriconazole resistance in Aspergillus flavus. Diagn Microbiol Infect Dis 76:458-463. http://dx.doi.org/10.1016/j.diagmicrobio.2013.04.022.
    • (2013) Diagn Microbiol Infect Dis , vol.76 , pp. 458-463
    • Natesan, S.K.1    Lamichchane, A.K.2    Swaminathan, S.3    Wu, W.4
  • 15
    • 84860197333 scopus 로고    scopus 로고
    • The T788G mutation in the cyp51C gene confers voriconazole resistance in Aspergillus flavus causing aspergillosis
    • Liu W, Sun Y, Chen W, Liu W, Wan Z, Bu D, Li R. 2012. The T788G mutation in the cyp51C gene confers voriconazole resistance in Aspergillus flavus causing aspergillosis. Antimicrob Agents Chemother 56:2598-2603. http://dx.doi.org/10.1128/AAC.05477-11.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 2598-2603
    • Liu, W.1    Sun, Y.2    Chen, W.3    Liu, W.4    Wan, Z.5    Bu, D.6    Li, R.7
  • 16
    • 79951496607 scopus 로고    scopus 로고
    • Use of epidemiological cutoff values to examine 9-year trends in susceptibility of Aspergillus species to the triazoles
    • Pfaller M, Boyken L, Hollis R, Kroeger J, Messer S, Tendolkar S, Diekema D. 2011. Use of epidemiological cutoff values to examine 9-year trends in susceptibility of Aspergillus species to the triazoles. J Clin Microbiol 49:586-590. http://dx.doi.org/10.1128/JCM.02136-10.
    • (2011) J Clin Microbiol , vol.49 , pp. 586-590
    • Pfaller, M.1    Boyken, L.2    Hollis, R.3    Kroeger, J.4    Messer, S.5    Tendolkar, S.6    Diekema, D.7
  • 17
    • 0028969372 scopus 로고
    • Development of primer sets designed for use with the PCR to amplify conserved genes from filamentous ascomycetes
    • Glass NL, Donaldson GC. 1995. Development of primer sets designed for use with the PCR to amplify conserved genes from filamentous ascomycetes. Appl Environ Microbiol 61:1323-1330.
    • (1995) Appl Environ Microbiol , vol.61 , pp. 1323-1330
    • Glass, N.L.1    Donaldson, G.C.2
  • 18
    • 0031940433 scopus 로고    scopus 로고
    • Cryptic speciation and recombination in the aflatoxin-producing fungus Aspergillus flavus
    • Geiser DM, Pitt JI, Taylor JW. 1998. Cryptic speciation and recombination in the aflatoxin-producing fungus Aspergillus flavus. Proc Natl Acad Sci U S A 95:388-393. http://dx.doi.org/10.1073/pnas.95.1.388.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 388-393
    • Geiser, D.M.1    Pitt, J.I.2    Taylor, J.W.3
  • 21
    • 80052794427 scopus 로고    scopus 로고
    • In vitro susceptibility of 188 clinical and environmental isolates of Aspergillus flavus for the new triazole isavuconazole and seven other antifungal drugs
    • Shivaprakash MR, Geertsen E, Chakrabarti A, Mouton JW, Meis JF. 2011. In vitro susceptibility of 188 clinical and environmental isolates of Aspergillus flavus for the new triazole isavuconazole and seven other antifungal drugs. Mycoses 54:e583-e589. http://dx.doi.org/10.1111/j.1439-0507.2010.01996.x.
    • (2011) Mycoses , vol.54 , pp. e583-e589
    • Shivaprakash, M.R.1    Geertsen, E.2    Chakrabarti, A.3    Mouton, J.W.4    Meis, J.F.5
  • 22
    • 82555166966 scopus 로고    scopus 로고
    • In vitro activity of isavuconazole against 208 aspergillus flavus isolates in comparison with 7 other antifungal agents: Assessment according to the methodology of the european committee on antimicrobial susceptibility testing
    • Rudramurthy SM, Chakrabarti A, Geertsen E, Mouton JW, Meis JF. 2011. In vitro activity of isavuconazole against 208 Aspergillus flavus isolates in comparison with 7 other antifungal agents: assessment according to the methodology of the European Committee on Antimicrobial Susceptibility Testing. Diagn Microbiol Infect Dis 71:370-377. http://dx.doi.org/10.1016/j.diagmicrobio.2011.08.006.
    • (2011) Diagn Microbiol Infect Dis , vol.71 , pp. 370-377
    • Rudramurthy, S.M.1    Chakrabarti, A.2    Geertsen, E.3    Mouton, J.W.4    Meis, J.F.5
  • 23
    • 78049484011 scopus 로고    scopus 로고
    • Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces
    • Venselaar H, Te Beek TA, Kuipers RK, Hekkelman ML, Vriend G. 2010. Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces. BMC Bioinformatics 11:548.
    • (2010) BMC Bioinformatics , vol.11 , pp. 548
    • Venselaar, H.1    Te Beek, T.A.2    Kuipers, R.K.3    Hekkelman, M.L.4    Vriend, G.5
  • 24
    • 84876580349 scopus 로고    scopus 로고
    • Sequence context of indel mutations and their effect on protein evolution in a bacterial endosymbiont
    • Williams LE, Wernegreen JJ. 2013. Sequence context of indel mutations and their effect on protein evolution in a bacterial endosymbiont. Genome Biol Evol 5:599-605. http://dx.doi.org/10.1093/gbe/evt033.
    • (2013) Genome Biol Evol , vol.5 , pp. 599-605
    • Williams, L.E.1    Wernegreen, J.J.2
  • 25
    • 80053259445 scopus 로고    scopus 로고
    • The structure-function relationship of the Aspergillus fumigatus cyp51A L98H conversion by site-directed mutagenesis: The mechanism of L98H azole resistance
    • Snelders E, Karawajczyk A, Verhoeven RJ, Venselaar H, Schaftenaar G, Verweij PE, Melchers WJ. 2011. The structure-function relationship of the Aspergillus fumigatus cyp51A L98H conversion by site-directed mutagenesis: the mechanism of L98H azole resistance. Fungal Genet Biol 48:1062-1070. http://dx.doi.org/10.1016/j.fgb.2011.08.002.
    • (2011) Fungal Genet Biol , vol.48 , pp. 1062-1070
    • Snelders, E.1    Karawajczyk, A.2    Verhoeven, R.J.3    Venselaar, H.4    Schaftenaar, G.5    Verweij, P.E.6    Melchers, W.J.7
  • 26
    • 80051595050 scopus 로고    scopus 로고
    • Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2
    • Wang J, Ma C, Fiorin G, Carnevale V, Wang T, Hu F, Lamb RA, Pinto LH, Hong M, Klein ML, DeGrado WF. 2011. Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2. J Am Chem Soc 133:12834-12841. http://dx.doi.org/10.1021/ja204969m.
    • (2011) J Am Chem Soc , vol.133 , pp. 12834-12841
    • Wang, J.1    Ma, C.2    Fiorin, G.3    Carnevale, V.4    Wang, T.5    Hu, F.6    Lamb, R.A.7    Pinto, L.H.8    Hong, M.9    Klein, M.L.10    DeGrado, W.F.11
  • 27
    • 84901321116 scopus 로고    scopus 로고
    • Use of long term molecular dynamics simulation in predicting cancer associated SNPs
    • Kumar A, Purohit R. 2014. Use of long term molecular dynamics simulation in predicting cancer associated SNPs. PLoS Comput Biol 10: e1003318. http://dx.doi.org/10.1371/journal.pcbi.1003318.
    • (2014) PLoS Comput Biol , vol.10 , pp. e1003318
    • Kumar, A.1    Purohit, R.2
  • 28
    • 84864660051 scopus 로고    scopus 로고
    • Understanding the basis of drug resistance of the mutants of αβ-tubulin dimer via molecular dynamics simulations
    • Natarajan K, Senapati S. 2012. Understanding the basis of drug resistance of the mutants of αβ-tubulin dimer via molecular dynamics simulations. PLoS One 7:e42351. http://dx.doi.org/10.1371/journal.pone.0042351.
    • (2012) PLoS One , vol.7 , pp. e42351
    • Natarajan, K.1    Senapati, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.