-
3
-
-
33646278256
-
-
Elsevier, Oxford, J.M. Anderson (Ed.)
-
Kim S.W., Kopecek J., Knutsen K. Advances in Drug Delivery Systems 1992, Part 5, Elsevier, Oxford. J.M. Anderson (Ed.).
-
(1992)
Advances in Drug Delivery Systems
-
-
Kim, S.W.1
Kopecek, J.2
Knutsen, K.3
-
4
-
-
33646278256
-
-
Elsevier, Amsterdam, J.M. Anderson (Ed.)
-
Kim S.W., Kopecek J., Knutsen K. Advances in Drug Delivery Systems 1994, Part 6, Elsevier, Amsterdam. J.M. Anderson (Ed.).
-
(1994)
Advances in Drug Delivery Systems
-
-
Kim, S.W.1
Kopecek, J.2
Knutsen, K.3
-
7
-
-
0003573951
-
-
Gordon and Breach Science Publisher, Gordon and Breach Science Publisher, New York
-
Okano T., Yui N., Yokoyama M., Yoshida R. Advances in Polymeric Systems for Drug Delivery 1994, Gordon and Breach Science Publisher, Gordon and Breach Science Publisher, New York.
-
(1994)
Advances in Polymeric Systems for Drug Delivery
-
-
Okano, T.1
Yui, N.2
Yokoyama, M.3
Yoshida, R.4
-
8
-
-
2442654441
-
Drug delivery systems
-
Barry B.W. Drug delivery systems. CHEMTECH 1983, 38-44.
-
(1983)
CHEMTECH
, pp. 38-44
-
-
Barry, B.W.1
-
9
-
-
0016622773
-
Structure and properties of pharmacologically active polymers
-
Ringsdorf H. Structure and properties of pharmacologically active polymers. J. Polym. Sci. Symp. 1975, 51:135-153.
-
(1975)
J. Polym. Sci. Symp.
, vol.51
, pp. 135-153
-
-
Ringsdorf, H.1
-
10
-
-
0016623634
-
Synthetic biologically active polymers
-
Donaruma L.G. Synthetic biologically active polymers. Prog. Polym. Sci. 1974, 4:1-25.
-
(1974)
Prog. Polym. Sci.
, vol.4
, pp. 1-25
-
-
Donaruma, L.G.1
-
11
-
-
1842313891
-
Polymeric drugs
-
Batz H.G. Polymeric drugs. Adv. Polym. Sci. 1977, 23:25-53.
-
(1977)
Adv. Polym. Sci.
, vol.23
, pp. 25-53
-
-
Batz, H.G.1
-
12
-
-
84942878066
-
Introduction to biology and medicine
-
Wiley, Tokyo, L.G. Donaruma, R.M. Ottenbrite, O. Vogl (Eds.)
-
Ottenbrite R.M. Introduction to biology and medicine. Anionic Polymeric Drugs 1980, Wiley, Tokyo. L.G. Donaruma, R.M. Ottenbrite, O. Vogl (Eds.).
-
(1980)
Anionic Polymeric Drugs
-
-
Ottenbrite, R.M.1
-
13
-
-
0002405110
-
Soluble synthetic polymers as potential drug carriers
-
Duncan R., Kopecek J. Soluble synthetic polymers as potential drug carriers. Adv. Polym. Sci. 1984, 57:51-101.
-
(1984)
Adv. Polym. Sci.
, vol.57
, pp. 51-101
-
-
Duncan, R.1
Kopecek, J.2
-
15
-
-
0041844743
-
Polymeric drug delivery systems
-
Academic Press, New York, E. Arlens (Ed.)
-
Kim S.W., Peterson R.V., Feijen J. Polymeric drug delivery systems. Drug Design 1980, vol. X:193-250. Academic Press, New York. E. Arlens (Ed.).
-
(1980)
Drug Design
, vol.10
, pp. 193-250
-
-
Kim, S.W.1
Peterson, R.V.2
Feijen, J.3
-
16
-
-
0022273714
-
Controlled release of drug model from N-(2-hydroxypropyl)methacrylamide copolymers
-
Kopecek J., Rejmanova P., Duncan R., Lloyd J.B. Controlled release of drug model from N-(2-hydroxypropyl)methacrylamide copolymers. Ann. NY Acad. Sci. 1985, 446:93-104.
-
(1985)
Ann. NY Acad. Sci.
, vol.446
, pp. 93-104
-
-
Kopecek, J.1
Rejmanova, P.2
Duncan, R.3
Lloyd, J.B.4
-
17
-
-
0024398880
-
Biocompatibility of N-(2-hydroxypropyl)-methacrylamide copolymers containing adriamycin. Immunogenicity, effect on hematopoietic stem cells in bone marrow in vivo and effect on mouse splenocytes and human peripheral blood lymphocytes in vitro
-
Rihova B., Ulbrich K., Strohalm J., Vetvicka V., Bilej M., Duncan R., Kopecek J. Biocompatibility of N-(2-hydroxypropyl)-methacrylamide copolymers containing adriamycin. Immunogenicity, effect on hematopoietic stem cells in bone marrow in vivo and effect on mouse splenocytes and human peripheral blood lymphocytes in vitro. Biomaterials 1989, 10:335-342.
-
(1989)
Biomaterials
, vol.10
, pp. 335-342
-
-
Rihova, B.1
Ulbrich, K.2
Strohalm, J.3
Vetvicka, V.4
Bilej, M.5
Duncan, R.6
Kopecek, J.7
-
18
-
-
0026757191
-
Drug-polymer conjugates: potential for improved chemotherapy
-
Duncan R. Drug-polymer conjugates: potential for improved chemotherapy. Anticancer Drugs 1992, 3:175-210.
-
(1992)
Anticancer Drugs
, vol.3
, pp. 175-210
-
-
Duncan, R.1
-
20
-
-
0011872749
-
Polymeric prodrugs, 6. Synthesis and examination of 6-purinethiol bound to poly(1-vinyl-2-pyrrolidone-co-maleic acid)
-
Mora M., Pato J., Tudos F. Polymeric prodrugs, 6. Synthesis and examination of 6-purinethiol bound to poly(1-vinyl-2-pyrrolidone-co-maleic acid). Makromol. Chem. 1989, 190:1967-1974.
-
(1989)
Makromol. Chem.
, vol.190
, pp. 1967-1974
-
-
Mora, M.1
Pato, J.2
Tudos, F.3
-
21
-
-
0011819599
-
Polymeric carriers of glycerol derivatives, 2. Chlorambucil derivatives
-
Soutif J.C., Mouity-Moussounda F., Brosse J.C. Polymeric carriers of glycerol derivatives, 2. Chlorambucil derivatives. Makromol. Chem. Rapid Commun. 1983, 4:61-64.
-
(1983)
Makromol. Chem. Rapid Commun.
, vol.4
, pp. 61-64
-
-
Soutif, J.C.1
Mouity-Moussounda, F.2
Brosse, J.C.3
-
22
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumourotropic accumulation of proteins and the antitumour agent smancs
-
Yasuhiro M., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumourotropic accumulation of proteins and the antitumour agent smancs. Cancer Res. 1986, 46:6387-6392.
-
(1986)
Cancer Res.
, vol.46
, pp. 6387-6392
-
-
Yasuhiro, M.1
Maeda, H.2
-
23
-
-
0018897432
-
Antitumour activity of monomeric and polymeric cyclophosphamide derivatives compared with in vitro hydrolysis
-
Hirano T., Ringsdorf H., Zaharko D.Z. Antitumour activity of monomeric and polymeric cyclophosphamide derivatives compared with in vitro hydrolysis. Cancer Res. 1980, 40:2263-2267.
-
(1980)
Cancer Res.
, vol.40
, pp. 2263-2267
-
-
Hirano, T.1
Ringsdorf, H.2
Zaharko, D.Z.3
-
24
-
-
0000268659
-
Pharmacologically active polymers. 17. Synthesis and characterization of polymeric derivatives of the antitumour agent methotrexate
-
Przybylski E., Fell E., Ringsdorf H., Zaharko D.Z. Pharmacologically active polymers. 17. Synthesis and characterization of polymeric derivatives of the antitumour agent methotrexate. Makromol. Chem. 1978, 179:1719-1733.
-
(1978)
Makromol. Chem.
, vol.179
, pp. 1719-1733
-
-
Przybylski, E.1
Fell, E.2
Ringsdorf, H.3
Zaharko, D.Z.4
-
25
-
-
0021751681
-
Polymer-drug combinations: pinocytic uptake of modified polysaccharides containing procaimide moieties by rat visceral yolk sacs cultured in vitro
-
Remon J.P., Duncan R., Schacht E. Polymer-drug combinations: pinocytic uptake of modified polysaccharides containing procaimide moieties by rat visceral yolk sacs cultured in vitro. J. Controlled Rel. 1984, 1:47-56.
-
(1984)
J. Controlled Rel.
, vol.1
, pp. 47-56
-
-
Remon, J.P.1
Duncan, R.2
Schacht, E.3
-
26
-
-
0022273726
-
Use of polysaccharides as drug carriers
-
Schacht E. Use of polysaccharides as drug carriers. Ann. Natl Acad. Sci. USA 1985, 446:199-212.
-
(1985)
Ann. Natl Acad. Sci. USA
, vol.446
, pp. 199-212
-
-
Schacht, E.1
-
27
-
-
0017874190
-
Higher antitumour efficacy of daunomycin when linked to dextran, in vivo and in vitro studies
-
Bernstein A., Hurwitz E., Maron R., Arnon R., Sela M., Wilchek M. Higher antitumour efficacy of daunomycin when linked to dextran, in vivo and in vitro studies. J. Natl Cancer Inst. 1978, 60:379-384.
-
(1978)
J. Natl Cancer Inst.
, vol.60
, pp. 379-384
-
-
Bernstein, A.1
Hurwitz, E.2
Maron, R.3
Arnon, R.4
Sela, M.5
Wilchek, M.6
-
28
-
-
0020417006
-
Search for carriers for non-covalent binding of interferon among 1,3,5-triazine derivatives of dextran
-
Konieezny M., Charytonowicz D., Inglot A.D. Search for carriers for non-covalent binding of interferon among 1,3,5-triazine derivatives of dextran. Arch. Immunol. Ther. Exp. 1982, 30:1-10.
-
(1982)
Arch. Immunol. Ther. Exp.
, vol.30
, pp. 1-10
-
-
Konieezny, M.1
Charytonowicz, D.2
Inglot, A.D.3
-
30
-
-
0022540475
-
Cellular interaction and in vitro antitumour activity of mitomycin C-dextran conjugate
-
Matsumoto S., Yamamoto A., Takakura Y., Hashida M., Sezaki H. Cellular interaction and in vitro antitumour activity of mitomycin C-dextran conjugate. Cancer Res. 1986, 46:4463-4468.
-
(1986)
Cancer Res.
, vol.46
, pp. 4463-4468
-
-
Matsumoto, S.1
Yamamoto, A.2
Takakura, Y.3
Hashida, M.4
Sezaki, H.5
-
31
-
-
0002881317
-
Dextrans as drug carriers
-
Academic Press, New York, G. Gregoriadis (Ed.)
-
Molteni L. Dextrans as drug carriers. Drug Carriers in Biology and Medicine 1979, 107-125. Academic Press, New York. G. Gregoriadis (Ed.).
-
(1979)
Drug Carriers in Biology and Medicine
, pp. 107-125
-
-
Molteni, L.1
-
32
-
-
0021343635
-
Bioactive polymers. XIV. Immobilization of ampicillin on biozan R
-
Simonescu C.R., Popa M.I., Dimitriu S. Bioactive polymers. XIV. Immobilization of ampicillin on biozan R. Z. Naturforsch. 1984, 39C:397-401.
-
(1984)
Z. Naturforsch.
, vol.39C
, pp. 397-401
-
-
Simonescu, C.R.1
Popa, M.I.2
Dimitriu, S.3
-
33
-
-
0019170967
-
Soluble macromolecules as carriers of daunomycin
-
Hurwitz E., Wilchek M., Pitha J. Soluble macromolecules as carriers of daunomycin. J. Appl. Biochem. 1980, 2:25-36.
-
(1980)
J. Appl. Biochem.
, vol.2
, pp. 25-36
-
-
Hurwitz, E.1
Wilchek, M.2
Pitha, J.3
-
34
-
-
0024789792
-
Antitumour activity of chitosan and chitin immobilized 5-fluorouracils through hexamethylene spacers via carbamoyl bonds
-
Ouchi Y., Banba T., Matsumoto T., Suzuki S., Suzuki M. Antitumour activity of chitosan and chitin immobilized 5-fluorouracils through hexamethylene spacers via carbamoyl bonds. J. Bioact. Biocomp. Pol. 1989, 4:362-371.
-
(1989)
J. Bioact. Biocomp. Pol.
, vol.4
, pp. 362-371
-
-
Ouchi, Y.1
Banba, T.2
Matsumoto, T.3
Suzuki, S.4
Suzuki, M.5
-
35
-
-
0000738920
-
Conjugation of methotrexate to poly(1-lysine) increases drug transport and overcomes drug resistance in cultured cells
-
Ryser H., Shen W.C. Conjugation of methotrexate to poly(1-lysine) increases drug transport and overcomes drug resistance in cultured cells. Proc. Natl Acad. Sci. USA 1978, 75:3867-3870.
-
(1978)
Proc. Natl Acad. Sci. USA
, vol.75
, pp. 3867-3870
-
-
Ryser, H.1
Shen, W.C.2
-
36
-
-
0019903935
-
Anti-tumour activity of daunorubicin linked to poly-L-aspartic acid
-
Zunino F., Giulliani F., Savi G., Dasdia T., Gambetta R. Anti-tumour activity of daunorubicin linked to poly-L-aspartic acid. J. Pharmacol. Exp. Ther. 1982, 30:465-469.
-
(1982)
J. Pharmacol. Exp. Ther.
, vol.30
, pp. 465-469
-
-
Zunino, F.1
Giulliani, F.2
Savi, G.3
Dasdia, T.4
Gambetta, R.5
-
37
-
-
0024851772
-
Polymeric prodrugs: α-β-poly(N-hydroxyethyl)-DL-aspartamide as macromolecular carrier for some non-steroidal antiinflammatory agents
-
Giammona G., Puglisi G., Carlisi B., Pignatello R., Spadaro A., Caruso A. Polymeric prodrugs: α-β-poly(N-hydroxyethyl)-DL-aspartamide as macromolecular carrier for some non-steroidal antiinflammatory agents. Int. J. Pharm. 1989, 57:55-62.
-
(1989)
Int. J. Pharm.
, vol.57
, pp. 55-62
-
-
Giammona, G.1
Puglisi, G.2
Carlisi, B.3
Pignatello, R.4
Spadaro, A.5
Caruso, A.6
-
38
-
-
0001400839
-
Polymères à propriétés pharmacologiques potentiels: greffage par liaison amide et (ou) ester d'un hypoglycémiant
-
Friedmann G., Aichaoui H., Brini M. Polymères à propriétés pharmacologiques potentiels: greffage par liaison amide et (ou) ester d'un hypoglycémiant. Makromol. Chem. 1981, 182:337-347.
-
(1981)
Makromol. Chem.
, vol.182
, pp. 337-347
-
-
Friedmann, G.1
Aichaoui, H.2
Brini, M.3
-
39
-
-
0011911034
-
Water-soluble polyamides as potential drug carriers. V. Carboxy-functionalized polyaspartamides and copolyaspartamides
-
De Machado M., Neuse E.W., Perlwitz A.G. Water-soluble polyamides as potential drug carriers. V. Carboxy-functionalized polyaspartamides and copolyaspartamides. Angew. Makromol. Chem. 1992, 195:35-56.
-
(1992)
Angew. Makromol. Chem.
, vol.195
, pp. 35-56
-
-
De Machado, M.1
Neuse, E.W.2
Perlwitz, A.G.3
-
41
-
-
0011859292
-
Targeting of antitumoral antiprotozoal drugs by covalent linkage to protein carriers
-
Plenum Press, London, G. Gregoriadis, J. Senior, A. Trouet (Eds.)
-
Trouet A., Baurain R., Deprez-De Campaneere D., Pirson P. Targeting of antitumoral antiprotozoal drugs by covalent linkage to protein carriers. Targeting of Drugs 1982, 19-30. Plenum Press, London. G. Gregoriadis, J. Senior, A. Trouet (Eds.).
-
(1982)
Targeting of Drugs
, pp. 19-30
-
-
Trouet, A.1
Baurain, R.2
Deprez-De Campaneere, D.3
Pirson, P.4
-
42
-
-
0018340546
-
Control of solid tumour metastases with a high molecular weight derivative of methotrexate
-
Chu B.C.F., Whiteley J.M. Control of solid tumour metastases with a high molecular weight derivative of methotrexate. J. Natl Cancer Inst. 1979, 62:79-82.
-
(1979)
J. Natl Cancer Inst.
, vol.62
, pp. 79-82
-
-
Chu, B.C.F.1
Whiteley, J.M.2
-
43
-
-
0001816926
-
Introduction to biotechnical and biomedical applications of poly(ethylene glycol)
-
Plenum Press, New York, J.M. Harris (Ed.)
-
Harris J.M. Introduction to biotechnical and biomedical applications of poly(ethylene glycol). Poly (ethylene glycol) Chemistry: Biotechnical and Biomedical Applications 1992, 1-14. Plenum Press, New York. J.M. Harris (Ed.).
-
(1992)
Poly (ethylene glycol) Chemistry: Biotechnical and Biomedical Applications
, pp. 1-14
-
-
Harris, J.M.1
-
44
-
-
0017701219
-
Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol
-
Abuchowski A., Es T.V., Palczuk N.C., Davis F.F. Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. J. Biol. Chem. 1977, 252:3578-3581.
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 3578-3581
-
-
Abuchowski, A.1
Es, T.V.2
Palczuk, N.C.3
Davis, F.F.4
-
45
-
-
0021248339
-
Cancer Therapy with chemically modified enzymes. 1. A property of polyethylene glycol asparaginase conjugates
-
Abuchowski A., Kazo G.M., Verhoest C.R., Van Es T., et al. Cancer Therapy with chemically modified enzymes. 1. A property of polyethylene glycol asparaginase conjugates. Cancer Bio. Chem. Biophys. 1984, 7:175-186.
-
(1984)
Cancer Bio. Chem. Biophys.
, vol.7
, pp. 175-186
-
-
Abuchowski, A.1
Kazo, G.M.2
Verhoest, C.R.3
Van Es, T.4
-
47
-
-
0019409884
-
Synthesis and Pharmacological evaluation of 4-isobutylphenyl-2-propionic acid (ibuprofen)
-
Cecchi R., Rusconi L., Tanzi M.C., Danusso F., Ferruti P. Synthesis and Pharmacological evaluation of 4-isobutylphenyl-2-propionic acid (ibuprofen). J. Med. Chem. 1981, 24:622-625.
-
(1981)
J. Med. Chem.
, vol.24
, pp. 622-625
-
-
Cecchi, R.1
Rusconi, L.2
Tanzi, M.C.3
Danusso, F.4
Ferruti, P.5
-
48
-
-
0021010277
-
Development of N-(2-hydroxypropyl)-methacrylamide copolymers as carriers of therapeutic agents
-
Plenum Press, New York, E. Chiellini, P. Guisti (Eds.)
-
Duncan R., Kopecek J., Lloyd J.B. Development of N-(2-hydroxypropyl)-methacrylamide copolymers as carriers of therapeutic agents. Polymers in Medicine: Biomedical and Pharmacological Applications 1983, 97-114. Plenum Press, New York. E. Chiellini, P. Guisti (Eds.).
-
(1983)
Polymers in Medicine: Biomedical and Pharmacological Applications
, pp. 97-114
-
-
Duncan, R.1
Kopecek, J.2
Lloyd, J.B.3
-
49
-
-
0020898456
-
Soluble synthetic polymers as targetable agents for intracellular drug release
-
Lloyd J.B., Duncan R., Pratten M.K. Soluble synthetic polymers as targetable agents for intracellular drug release. Br. Polym. J. 1983, 15:158-159.
-
(1983)
Br. Polym. J.
, vol.15
, pp. 158-159
-
-
Lloyd, J.B.1
Duncan, R.2
Pratten, M.K.3
-
50
-
-
0020682412
-
Targeting of N-(2-hydroxypropyl)-methacrylamide copolymers to liver by incorporation of galactose residues
-
Duncan R., Kopecek J., Rejmanova P., Lloyd J.B. Targeting of N-(2-hydroxypropyl)-methacrylamide copolymers to liver by incorporation of galactose residues. Biochem. Biophys. Acta 1983, 755:518-521.
-
(1983)
Biochem. Biophys. Acta
, vol.755
, pp. 518-521
-
-
Duncan, R.1
Kopecek, J.2
Rejmanova, P.3
Lloyd, J.B.4
-
51
-
-
0026069645
-
Synthetic polymers conjugated to monoclonal antibodies: vehicles for tumour-targeted drug delivery
-
Seymour L.W., Flanagan P.A., Al-Shamkhani A., Subr V., Ulbrich K., Cassidy J., Duncan R. Synthetic polymers conjugated to monoclonal antibodies: vehicles for tumour-targeted drug delivery. Select. Cancer Ther. 1991, 7:59-73.
-
(1991)
Select. Cancer Ther.
, vol.7
, pp. 59-73
-
-
Seymour, L.W.1
Flanagan, P.A.2
Al-Shamkhani, A.3
Subr, V.4
Ulbrich, K.5
Cassidy, J.6
Duncan, R.7
-
52
-
-
0024439808
-
Evaluation of antibody-N-(2-hydroxypropyl)-methacrylamide copolymer conjugates as targetable drug-carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and anti-transferrin receptor antibody-conjugates
-
Flanagan P.A., Kopeckova P., Kopecek J., Duncan R. Evaluation of antibody-N-(2-hydroxypropyl)-methacrylamide copolymer conjugates as targetable drug-carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and anti-transferrin receptor antibody-conjugates. Biochim. Biophys. Acta 1989, 993:83-91.
-
(1989)
Biochim. Biophys. Acta
, vol.993
, pp. 83-91
-
-
Flanagan, P.A.1
Kopeckova, P.2
Kopecek, J.3
Duncan, R.4
-
53
-
-
0023450012
-
Effect of molecular weight of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal and intravenous administration to rats
-
Seymour L.W., Duncan R., Strohalm J., Kopecek J. Effect of molecular weight of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal and intravenous administration to rats. J. Biomed. Mater. Res. 1987, 21:1341-1358.
-
(1987)
J. Biomed. Mater. Res.
, vol.21
, pp. 1341-1358
-
-
Seymour, L.W.1
Duncan, R.2
Strohalm, J.3
Kopecek, J.4
-
55
-
-
0037087719
-
Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin
-
Seymour L.W., Ferry D.R., Anderson D., Hesslewood S., et al. Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin. J. Clin. Oncol. 2002, 20:1668-1676.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1668-1676
-
-
Seymour, L.W.1
Ferry, D.R.2
Anderson, D.3
Hesslewood, S.4
-
56
-
-
0035012701
-
Phase I clinical and pharmacokinetic study of PNU166945, a novel water-soluble polymer-conjugated prodrug of paclitaxel
-
Terwogt J.M.M., Huinink W.W.T., Schellens J.H.M., Schot M., et al. Phase I clinical and pharmacokinetic study of PNU166945, a novel water-soluble polymer-conjugated prodrug of paclitaxel. Anticancer Drugs 2001, 12:315-323.
-
(2001)
Anticancer Drugs
, vol.12
, pp. 315-323
-
-
Terwogt, J.M.M.1
Huinink, W.W.T.2
Schellens, J.H.M.3
Schot, M.4
-
57
-
-
70449273550
-
Biological properties of poly-α-amino acids
-
Sela M., Katchalski E. Biological properties of poly-α-amino acids. Adv. Protein Chem. 1959, 14:391-478.
-
(1959)
Adv. Protein Chem.
, vol.14
, pp. 391-478
-
-
Sela, M.1
Katchalski, E.2
-
58
-
-
0028414109
-
Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes
-
Monsigny M., Roche A.C., Midoux P., Mayer R. Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes. Adv. Drug Del. Rev. 1994, 14:1-24.
-
(1994)
Adv. Drug Del. Rev.
, vol.14
, pp. 1-24
-
-
Monsigny, M.1
Roche, A.C.2
Midoux, P.3
Mayer, R.4
-
59
-
-
0026939267
-
Effect of the chemical modification of dextran on the degradation by rat liver lysosomal enzymes
-
Vercauteren R., Schacht E., Duncan R. Effect of the chemical modification of dextran on the degradation by rat liver lysosomal enzymes. J. Bioact. Biocomp. Polym. 1992, 7:346-357.
-
(1992)
J. Bioact. Biocomp. Polym.
, vol.7
, pp. 346-357
-
-
Vercauteren, R.1
Schacht, E.2
Duncan, R.3
-
60
-
-
0028419623
-
Drug Targeting to the kidney with low-molecular weight proteins
-
Franssen E.J.F., Moolenaar F., De Zeeuw D., Meijer D.K.F. Drug Targeting to the kidney with low-molecular weight proteins. Adv. Drug Del. Rev. 1994, 14:67-88.
-
(1994)
Adv. Drug Del. Rev.
, vol.14
, pp. 67-88
-
-
Franssen, E.J.F.1
Moolenaar, F.2
De Zeeuw, D.3
Meijer, D.K.F.4
-
61
-
-
0028418574
-
Soluble polymers for lectin-mediated drug targeting
-
Seymour L.W. Soluble polymers for lectin-mediated drug targeting. Adv. Drug Del. Rev. 1994, 14:89-112.
-
(1994)
Adv. Drug Del. Rev.
, vol.14
, pp. 89-112
-
-
Seymour, L.W.1
-
62
-
-
0025343062
-
Characterization and anticancer activity of the micelle forming polymeric anti-cancer drug adriamycinconjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
-
Yokoyama M., Miyauchi M., Yamada N., Okano T., Sakurai Y., Kataoka K., Inoue S. Characterization and anticancer activity of the micelle forming polymeric anti-cancer drug adriamycinconjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. Cancer Res. 1990, 50:1693-1700.
-
(1990)
Cancer Res.
, vol.50
, pp. 1693-1700
-
-
Yokoyama, M.1
Miyauchi, M.2
Yamada, N.3
Okano, T.4
Sakurai, Y.5
Kataoka, K.6
Inoue, S.7
-
63
-
-
0025874282
-
Toxicity and anti-tumour activity against solid tumours of micelle-forming polymeric anti-cancer drug and its extremely long circulation in blood
-
Yokoyama M., Okano T., Sakurai Y., Ekimoto H., Shibazaki C., Kataoka K. Toxicity and anti-tumour activity against solid tumours of micelle-forming polymeric anti-cancer drug and its extremely long circulation in blood. Cancer Res. 1991, 51:3229-3236.
-
(1991)
Cancer Res.
, vol.51
, pp. 3229-3236
-
-
Yokoyama, M.1
Okano, T.2
Sakurai, Y.3
Ekimoto, H.4
Shibazaki, C.5
Kataoka, K.6
-
65
-
-
0005106988
-
Selective endocytosis of macromolecular drug carriers
-
Marcel Dekker, New York, J.R. Robinson, V.H. Lee (Eds.)
-
Duncan R. Selective endocytosis of macromolecular drug carriers. Controlled Drug Delivery: Fundamentals and Applications 1987, 581-607. Marcel Dekker, New York. 2nd edn. J.R. Robinson, V.H. Lee (Eds.).
-
(1987)
Controlled Drug Delivery: Fundamentals and Applications
, pp. 581-607
-
-
Duncan, R.1
-
66
-
-
0006052482
-
A covalent linkage between daunorubicin and protein that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies
-
Trouet A., Masquelier M., Baurain R., Deprez-De Campeneere D. A covalent linkage between daunorubicin and protein that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies. Proc. Natl Acad. Sci. USA 1982, 79:626-629.
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 626-629
-
-
Trouet, A.1
Masquelier, M.2
Baurain, R.3
Deprez-De Campeneere, D.4
-
67
-
-
0026584015
-
Polymers containing enzymatically degradable bonds, XII. Effect of spacer structure on the rate of release of daunomycin and adriamycin from poly[N-(2-hydroxypropyl)-methacrylamide] copolymer drug carriers in vitro and antitumour activity measured in vivo
-
Subr V., Strohalm J., Ulbrich K., Duncan R., Hume Z. Polymers containing enzymatically degradable bonds, XII. Effect of spacer structure on the rate of release of daunomycin and adriamycin from poly[N-(2-hydroxypropyl)-methacrylamide] copolymer drug carriers in vitro and antitumour activity measured in vivo. J. Controlled Rel. 1992, 18:123-132.
-
(1992)
J. Controlled Rel.
, vol.18
, pp. 123-132
-
-
Subr, V.1
Strohalm, J.2
Ulbrich, K.3
Duncan, R.4
Hume, Z.5
-
68
-
-
0028023917
-
Evaluation of the hydrolytic and enzymatic stability of macromolecular mitomycin C derivatives
-
De Marre A., Seymour L.W., Schacht E.H. Evaluation of the hydrolytic and enzymatic stability of macromolecular mitomycin C derivatives. J. Controlled Res. 1994, 31:89-97.
-
(1994)
J. Controlled Res.
, vol.31
, pp. 89-97
-
-
De Marre, A.1
Seymour, L.W.2
Schacht, E.H.3
-
69
-
-
0032976042
-
Drug-polymer conjugates containing acid-cleavable bonds carrier systems
-
Kratz F., Beyer U., Schütte M.T. Drug-polymer conjugates containing acid-cleavable bonds carrier systems. Crit. Rev. Ther. Drug Carrier Syst. 1999, 16:245-288.
-
(1999)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.16
, pp. 245-288
-
-
Kratz, F.1
Beyer, U.2
Schütte, M.T.3
-
70
-
-
0026164319
-
New hydrazone derivatives of adriamycin and their immunoconjugates. A correlation between acid stability and cytotoxicity
-
Kaneko T., Willner D., Monkovic I., Knipe J.O., et al. New hydrazone derivatives of adriamycin and their immunoconjugates. A correlation between acid stability and cytotoxicity. Bioconjugate Chem. 1991, 2:133-141.
-
(1991)
Bioconjugate Chem.
, vol.2
, pp. 133-141
-
-
Kaneko, T.1
Willner, D.2
Monkovic, I.3
Knipe, J.O.4
-
71
-
-
0031886252
-
Preparation, characterization and in vitro efficacy of albumin conjugates of doxorubicin
-
Kratz F., Beyer U., Collery P., Lechenault F., et al. Preparation, characterization and in vitro efficacy of albumin conjugates of doxorubicin. Biol. Pharm. Bull. 1998, 21:56-61.
-
(1998)
Biol. Pharm. Bull.
, vol.21
, pp. 56-61
-
-
Kratz, F.1
Beyer, U.2
Collery, P.3
Lechenault, F.4
-
72
-
-
0029981640
-
Synthesis of polyglutamine and dextran conjugates of streptomycin with an acid-sensitive drug-carrier linkage
-
Coessens V., Schacht E., Domurado D. Synthesis of polyglutamine and dextran conjugates of streptomycin with an acid-sensitive drug-carrier linkage. J. Controlled Rel. 1996, 38:141-150.
-
(1996)
J. Controlled Rel.
, vol.38
, pp. 141-150
-
-
Coessens, V.1
Schacht, E.2
Domurado, D.3
-
73
-
-
0019786031
-
Cis-aconityl spacer between daunomycin and macromolecular carriers: a model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate
-
Shen W.C., Ryser H.J.P. Cis-aconityl spacer between daunomycin and macromolecular carriers: a model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate. Biochem. Biophys. Res. Commun. 1981, 102:1048-1054.
-
(1981)
Biochem. Biophys. Res. Commun.
, vol.102
, pp. 1048-1054
-
-
Shen, W.C.1
Ryser, H.J.P.2
-
74
-
-
0022227637
-
Disulfide spacer between methotrexate and poly(D-lysine)
-
Shen W.C., Ryser H.J.P., La Manna L. Disulfide spacer between methotrexate and poly(D-lysine). J. Biol. Chem. 1985, 260:10905-10908.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 10905-10908
-
-
Shen, W.C.1
Ryser, H.J.P.2
La Manna, L.3
-
75
-
-
0026926609
-
Conjugates of anticancer agents and polymer: advantages of macromolecular therapeutics in vivo
-
Maeda H., Seymour L.W., Miyamoto Y. Conjugates of anticancer agents and polymer: advantages of macromolecular therapeutics in vivo. Bioconj. Chem. 1992, 3:351-362.
-
(1992)
Bioconj. Chem.
, vol.3
, pp. 351-362
-
-
Maeda, H.1
Seymour, L.W.2
Miyamoto, Y.3
-
76
-
-
0025359853
-
The pharmacokinetics of polymer-bound adriamycin
-
Seymour L.W., Ulbrich K., Strohalm J., Duncan R. The pharmacokinetics of polymer-bound adriamycin. Biochem. Pharmacol. 1990, 39:1125-1131.
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 1125-1131
-
-
Seymour, L.W.1
Ulbrich, K.2
Strohalm, J.3
Duncan, R.4
-
77
-
-
0023240259
-
Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. 1. Physicochemical characteristics and in vitro and in vivo antitumour activities
-
Takakura Y., Kitajima M., Matsumoto S., Hashida M., Sezaki H. Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. 1. Physicochemical characteristics and in vitro and in vivo antitumour activities. Int. J. Pharm. 1987, 37:135-143.
-
(1987)
Int. J. Pharm.
, vol.37
, pp. 135-143
-
-
Takakura, Y.1
Kitajima, M.2
Matsumoto, S.3
Hashida, M.4
Sezaki, H.5
-
79
-
-
0023779745
-
Chemical modification of superoxide dismutase. Extension of plasma half-life of the enzyme through its reversible binding to circulating albumin
-
Ogino T., Inoue M., Ando Y., Arai H., Morino Y. Chemical modification of superoxide dismutase. Extension of plasma half-life of the enzyme through its reversible binding to circulating albumin. Int. J. Peptide Protein Res. 1988, 32:153-159.
-
(1988)
Int. J. Peptide Protein Res.
, vol.32
, pp. 153-159
-
-
Ogino, T.1
Inoue, M.2
Ando, Y.3
Arai, H.4
Morino, Y.5
-
80
-
-
0017388651
-
Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase
-
Abuchowski A., McCoy J.R., Palczuk N.C., Es T.V., Davis F.F. Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase. J. Biol. Chem. 1977, 252:3582-3586.
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 3582-3586
-
-
Abuchowski, A.1
McCoy, J.R.2
Palczuk, N.C.3
Es, T.V.4
Davis, F.F.5
-
81
-
-
0019461927
-
Reduction in immunogenicity and clearance rate of Escherichia colil-asparaginase by modification with monomethoxypoly(ethylene glycol)
-
Kamisaki Y., Wada H., Yagura H., Matsushima A., Inada Y. Reduction in immunogenicity and clearance rate of Escherichia colil-asparaginase by modification with monomethoxypoly(ethylene glycol). J. Pharmacol. Exp. Ther. 1981, 216:410-414.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.216
, pp. 410-414
-
-
Kamisaki, Y.1
Wada, H.2
Yagura, H.3
Matsushima, A.4
Inada, Y.5
-
82
-
-
0027299899
-
Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure
-
Li C.J., Miyamoto Y., Kojima Y., Maeda H. Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure. Br. J. Cancer 1993, 67:975-980.
-
(1993)
Br. J. Cancer
, vol.67
, pp. 975-980
-
-
Li, C.J.1
Miyamoto, Y.2
Kojima, Y.3
Maeda, H.4
-
83
-
-
0019478990
-
A new approach to cancer chemotherapy: a selective enhancement of tumour blood flow with angiotensin II
-
Suzuki M., Hori K., Abe I., Saito S., Sato H. A new approach to cancer chemotherapy: a selective enhancement of tumour blood flow with angiotensin II. J. Natl. Cancer Inst. 1981, 67:663-669.
-
(1981)
J. Natl. Cancer Inst.
, vol.67
, pp. 663-669
-
-
Suzuki, M.1
Hori, K.2
Abe, I.3
Saito, S.4
Sato, H.5
-
84
-
-
0026079974
-
Fluctuation in tumour blood flow under normotension and the effect of angiotensin II induced hypertension
-
Hori K., Suzuki M., Tanda S., Saito S., Shiozaki S., Zhang Q.H. Fluctuation in tumour blood flow under normotension and the effect of angiotensin II induced hypertension. Jpn. J. Cancer Res. 1991, 82:1309-1316.
-
(1991)
Jpn. J. Cancer Res.
, vol.82
, pp. 1309-1316
-
-
Hori, K.1
Suzuki, M.2
Tanda, S.3
Saito, S.4
Shiozaki, S.5
Zhang, Q.H.6
-
85
-
-
0023522375
-
Chemoembolisation in regional cancer chemotherapy: a rationale
-
Willmott N. Chemoembolisation in regional cancer chemotherapy: a rationale. Cancer Treat. Rev. 1987, 14:143-156.
-
(1987)
Cancer Treat. Rev.
, vol.14
, pp. 143-156
-
-
Willmott, N.1
-
86
-
-
0026118760
-
SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy
-
Maeda H. SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy. Drug Delivery Rev. 1991, 6:181-202.
-
(1991)
Drug Delivery Rev.
, vol.6
, pp. 181-202
-
-
Maeda, H.1
-
87
-
-
0022512127
-
Stability of high molecular weight anticancer agent SMANCS and its transfer from oil-phase to water-phase
-
Hirayama S., Sato F., Oda T., Maeda H. Stability of high molecular weight anticancer agent SMANCS and its transfer from oil-phase to water-phase. Jpn J. Antibiot. 1986, 39:815-822.
-
(1986)
Jpn J. Antibiot.
, vol.39
, pp. 815-822
-
-
Hirayama, S.1
Sato, F.2
Oda, T.3
Maeda, H.4
-
88
-
-
0026535566
-
The tumour blood vessel as an ideal target for macromolecular anticancer agents
-
Maeda H. The tumour blood vessel as an ideal target for macromolecular anticancer agents. J. Controlled Rel. 1992, 19:315-324.
-
(1992)
J. Controlled Rel.
, vol.19
, pp. 315-324
-
-
Maeda, H.1
-
89
-
-
0020525867
-
Effect of arterial administration of high-molecular-weight anticancer agent SMANCS with lipid lymphographic agent on hepatoma: a preliminary report
-
Konno T., Maeda H., Iwai K., Tashiro S., Mati S., Morinaga T., Mochinaga M., Hiraoka T., Yokoyama I. Effect of arterial administration of high-molecular-weight anticancer agent SMANCS with lipid lymphographic agent on hepatoma: a preliminary report. Eur. J. Cancer Clin. Oncol. 1983, 19:1053-1065.
-
(1983)
Eur. J. Cancer Clin. Oncol.
, vol.19
, pp. 1053-1065
-
-
Konno, T.1
Maeda, H.2
Iwai, K.3
Tashiro, S.4
Mati, S.5
Morinaga, T.6
Mochinaga, M.7
Hiraoka, T.8
Yokoyama, I.9
-
90
-
-
0002649813
-
Targeting chemotherapy of hepatocellular carcinoma: arterial administration of smancs/lipiodol
-
chap. 27, Springer-Verlag, New York, K. Okuda, K.G. Ishak (Eds.)
-
Konno T., Maeda H. Targeting chemotherapy of hepatocellular carcinoma: arterial administration of smancs/lipiodol. Neoplasms of the Liver 1987, 343-352. chap. 27, Springer-Verlag, New York. K. Okuda, K.G. Ishak (Eds.).
-
(1987)
Neoplasms of the Liver
, pp. 343-352
-
-
Konno, T.1
Maeda, H.2
-
91
-
-
0027218284
-
Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates
-
Trail P.A., Willner D., Lasch S.J., Henderson A.J., Hofstead S., Casazza A.M., Firestone R.A., Hellstrom K.E. Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates. Science 1993, 261:212-215.
-
(1993)
Science
, vol.261
, pp. 212-215
-
-
Trail, P.A.1
Willner, D.2
Lasch, S.J.3
Henderson, A.J.4
Hofstead, S.5
Casazza, A.M.6
Firestone, R.A.7
Hellstrom, K.E.8
-
93
-
-
0026375173
-
Phase I immunotoxin trial in patients with B-cell lymphoma
-
Vitetta E.S., Stone M., Amlot P., Fay J., et al. Phase I immunotoxin trial in patients with B-cell lymphoma. Cancer Res. 1991, 51:4052-4058.
-
(1991)
Cancer Res.
, vol.51
, pp. 4052-4058
-
-
Vitetta, E.S.1
Stone, M.2
Amlot, P.3
Fay, J.4
-
94
-
-
0027173613
-
A monoclonal antibody detects heterogenicity in vascular endothelium of tumours and normal tissues
-
Wang J.M., Kumar S., Pye D., Van Agthoven A.J., Krupinski J., Hunter R.D. A monoclonal antibody detects heterogenicity in vascular endothelium of tumours and normal tissues. Int. J. Cancer 1993, 54:363-370.
-
(1993)
Int. J. Cancer
, vol.54
, pp. 363-370
-
-
Wang, J.M.1
Kumar, S.2
Pye, D.3
Van Agthoven, A.J.4
Krupinski, J.5
Hunter, R.D.6
-
95
-
-
0027368441
-
Eradication of large solid tumours in mice with an immunotoxin directed against tumour vasculature
-
Burrows F.J., Thorpe P.E. Eradication of large solid tumours in mice with an immunotoxin directed against tumour vasculature. Proc. Natl. Acad. Sci. 1993, 90:8996-9000.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 8996-9000
-
-
Burrows, F.J.1
Thorpe, P.E.2
-
96
-
-
0024246527
-
A cytotoxic agent can be generated selectively at cancer sites
-
Bagshawe K.D., Springer C.J., Searle F., Antoniw P., Sharma S.K., Melton R.G., Sherwood R.F. A cytotoxic agent can be generated selectively at cancer sites. Br. J. Cancer 1988, 58:700-703.
-
(1988)
Br. J. Cancer
, vol.58
, pp. 700-703
-
-
Bagshawe, K.D.1
Springer, C.J.2
Searle, F.3
Antoniw, P.4
Sharma, S.K.5
Melton, R.G.6
Sherwood, R.F.7
-
97
-
-
0025955579
-
Ablation of human choriocarcinoma xenografts in nude mice by antibody-directed enzyme prodrug therapy (ADEPT) with three novel compounds
-
Springer C.J., Bagshawe K.D., Sharma S.K., Searle F., et al. Ablation of human choriocarcinoma xenografts in nude mice by antibody-directed enzyme prodrug therapy (ADEPT) with three novel compounds. Eur. J. Cancer 1991, 27:1361-1366.
-
(1991)
Eur. J. Cancer
, vol.27
, pp. 1361-1366
-
-
Springer, C.J.1
Bagshawe, K.D.2
Sharma, S.K.3
Searle, F.4
-
98
-
-
0026250463
-
Generation of 5-fluorouracil from 5-fluorocytosine by monoclonal antibody-cytosine deaminase conjugates
-
Senter P.D., Su P.D.D., Katsuragi T., Sakai T., et al. Generation of 5-fluorouracil from 5-fluorocytosine by monoclonal antibody-cytosine deaminase conjugates. Bioconjugate Chem. 1991, 2:447-451.
-
(1991)
Bioconjugate Chem.
, vol.2
, pp. 447-451
-
-
Senter, P.D.1
Su, P.D.D.2
Katsuragi, T.3
Sakai, T.4
-
99
-
-
0025720744
-
Antibody directed enzyme prodrug therapy (ADEPT): a three-phase system.
-
Sharma, S.K., Bagshawe, K.D., Springer, C.J., Burge, P.J., et al. Antibody directed enzyme prodrug therapy (ADEPT): a three-phase system. Disease Markers9: 225-231.
-
Disease Markers
, vol.9
, pp. 225-231
-
-
Sharma, S.K.1
Bagshawe, K.D.2
Springer, C.J.3
Burge, P.J.4
-
100
-
-
27844470091
-
What should be called a lectin?
-
Goldstein I.J., Hugues R.C., Monsigny M., Osawa T., Sharon N. What should be called a lectin?. Nature 1980, 285:66.
-
(1980)
Nature
, vol.285
, pp. 66
-
-
Goldstein, I.J.1
Hugues, R.C.2
Monsigny, M.3
Osawa, T.4
Sharon, N.5
-
101
-
-
0020021127
-
Carbohydrate-specific receptors of the liver
-
Ashwell G., Harford J. Carbohydrate-specific receptors of the liver. Annu. Rev. Biochem. 1982, 51:531-554.
-
(1982)
Annu. Rev. Biochem.
, vol.51
, pp. 531-554
-
-
Ashwell, G.1
Harford, J.2
-
102
-
-
0024414280
-
Lectins as cell recognition molecules
-
Sharon N., Lis H. Lectins as cell recognition molecules. Science 1989, 246:227-234.
-
(1989)
Science
, vol.246
, pp. 227-234
-
-
Sharon, N.1
Lis, H.2
-
104
-
-
0016260069
-
Lysosomotropic agents
-
De Duve C., De Barsy T., Poole B., Trouet A., et al. Lysosomotropic agents. Biochem. Pharmacol. 1974, 23:2495-2531.
-
(1974)
Biochem. Pharmacol.
, vol.23
, pp. 2495-2531
-
-
De Duve, C.1
De Barsy, T.2
Poole, B.3
Trouet, A.4
-
105
-
-
0021192483
-
The hepatic asialoglycoprotein receptor
-
Schwartz A.L. The hepatic asialoglycoprotein receptor. CRC Crit. Rev. Biochem. 1984, 16:207-233.
-
(1984)
CRC Crit. Rev. Biochem.
, vol.16
, pp. 207-233
-
-
Schwartz, A.L.1
-
106
-
-
0025780397
-
Fate of glycosylated dextrans after in vivo administration
-
Vansteenkiste S., Schacht E., Duncan R., Seymour L., Pawluczyk I., Baldwin R. Fate of glycosylated dextrans after in vivo administration. J. Controlled Rel. 1991, 16:91-100.
-
(1991)
J. Controlled Rel.
, vol.16
, pp. 91-100
-
-
Vansteenkiste, S.1
Schacht, E.2
Duncan, R.3
Seymour, L.4
Pawluczyk, I.5
Baldwin, R.6
-
108
-
-
0028825496
-
In vitro binding specificity of glycosylated dextrans to the asialoglycoprotein receptor of primary hepatocytes
-
Anderson D., Vansteenkiste S., Schacht E.H., Sen S.V., Seymour L.W. In vitro binding specificity of glycosylated dextrans to the asialoglycoprotein receptor of primary hepatocytes. Eur. J. Pharm. 1994, 3:339-345.
-
(1994)
Eur. J. Pharm.
, vol.3
, pp. 339-345
-
-
Anderson, D.1
Vansteenkiste, S.2
Schacht, E.H.3
Sen, S.V.4
Seymour, L.W.5
-
109
-
-
0026083903
-
Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma
-
Weidner N., Semple J.P., Welch W.R., Folkman J. Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. N. Engl J Med. 1991, 324:1-8.
-
(1991)
N. Engl J Med.
, vol.324
, pp. 1-8
-
-
Weidner, N.1
Semple, J.P.2
Welch, W.R.3
Folkman, J.4
-
110
-
-
0032577571
-
Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the border
-
Yancopoulos G.D., Klagsbrun M., Folkman J. Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the border. Cell 1998, 93:661-664.
-
(1998)
Cell
, vol.93
, pp. 661-664
-
-
Yancopoulos, G.D.1
Klagsbrun, M.2
Folkman, J.3
-
112
-
-
0028846008
-
VEGF-mediated tumor angiogenesis - a new target for cancer-therapy
-
Martiny-Baron G., Marme D. VEGF-mediated tumor angiogenesis - a new target for cancer-therapy. Curr. Opin. Biotechnol. 1995, 6:675-680.
-
(1995)
Curr. Opin. Biotechnol.
, vol.6
, pp. 675-680
-
-
Martiny-Baron, G.1
Marme, D.2
-
114
-
-
0022508987
-
A synthetic peptide from fibronectin inhibits experimental metastasis of muring melanoma cells
-
Humphries M.J., Olden K., Yamada K.M. A synthetic peptide from fibronectin inhibits experimental metastasis of muring melanoma cells. Science 1986, 233:467-470.
-
(1986)
Science
, vol.233
, pp. 467-470
-
-
Humphries, M.J.1
Olden, K.2
Yamada, K.M.3
-
115
-
-
0032535999
-
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
-
Arap W., Pasqualini R., Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998, 279:377-380.
-
(1998)
Science
, vol.279
, pp. 377-380
-
-
Arap, W.1
Pasqualini, R.2
Ruoslahti, E.3
-
116
-
-
0031392198
-
Amino acids and peptides XXX. Preparation of Arg-Gly-Asp (RGD) hybrids with poly(ethylene glycol) analogs and their antimetastatic effect
-
Maeda M., Izuno Y., Kawasaki K., Kaneda Y., et al. Amino acids and peptides XXX. Preparation of Arg-Gly-Asp (RGD) hybrids with poly(ethylene glycol) analogs and their antimetastatic effect. Chem. Pharm. Bull. 1997, 45:1788-1792.
-
(1997)
Chem. Pharm. Bull.
, vol.45
, pp. 1788-1792
-
-
Maeda, M.1
Izuno, Y.2
Kawasaki, K.3
Kaneda, Y.4
-
117
-
-
0037035443
-
Nitric oxide and angiogenesis
-
Cooke J.P., Losordo D.W. Nitric oxide and angiogenesis. Circulation 2002, 105:2133-2135.
-
(2002)
Circulation
, vol.105
, pp. 2133-2135
-
-
Cooke, J.P.1
Losordo, D.W.2
-
118
-
-
0014962562
-
Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase
-
Fridovich L. Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J. Biol. Chem. 1970, 245:4053-4057.
-
(1970)
J. Biol. Chem.
, vol.245
, pp. 4053-4057
-
-
Fridovich, L.1
-
119
-
-
0033965528
-
Tumor-targeting chemotherapy by a xanthine oxidase-polymer conjugate that generates oxygen-free radicals in tumor tissue
-
Sawa T., Wu J., Akaike T., Maeda H. Tumor-targeting chemotherapy by a xanthine oxidase-polymer conjugate that generates oxygen-free radicals in tumor tissue. Cancer Res. 2000, 60:666-671.
-
(2000)
Cancer Res.
, vol.60
, pp. 666-671
-
-
Sawa, T.1
Wu, J.2
Akaike, T.3
Maeda, H.4
-
120
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumouritropic accumulation of proteins and antitumour agent SMANCS
-
Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumouritropic accumulation of proteins and antitumour agent SMANCS. Cancer Res. 1986, 46:6387-6392.
-
(1986)
Cancer Res.
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
121
-
-
0024994008
-
Vascular and interstitial barriers to the delivery of therapeutic agents in tumours
-
Jain R.K. Vascular and interstitial barriers to the delivery of therapeutic agents in tumours. Cancer Metast. Rev. 1991, 9:253-266.
-
(1991)
Cancer Metast. Rev.
, vol.9
, pp. 253-266
-
-
Jain, R.K.1
-
122
-
-
0027359953
-
Vascular permeability factor in tumour biology
-
Senger D.R., Van de Water L., Brown I.F., Nagy J.A., Yeo K.T., et al. Vascular permeability factor in tumour biology. Cancer Metast. Rev. 1993, 12:303-324.
-
(1993)
Cancer Metast. Rev.
, vol.12
, pp. 303-324
-
-
Senger, D.R.1
Van de Water, L.2
Brown, I.F.3
Nagy, J.A.4
Yeo, K.T.5
-
123
-
-
0017874190
-
Higher antitumour efficacy of daunomycin when linked to dextran: in vivo and in vitro studies
-
Berstein A., Hurwitz E., Maron R., Arnon R., et al. Higher antitumour efficacy of daunomycin when linked to dextran: in vivo and in vitro studies. J. Natl Cancer Inst. 1978, 60:379-384.
-
(1978)
J. Natl Cancer Inst.
, vol.60
, pp. 379-384
-
-
Berstein, A.1
Hurwitz, E.2
Maron, R.3
Arnon, R.4
-
124
-
-
0023222593
-
Increased therapeutic efficacy and reduced toxicity of doxorubicin linked to pyran copolymer via the side chain of the drug
-
Zunino F., Pratesi G., Pezzoni G. Increased therapeutic efficacy and reduced toxicity of doxorubicin linked to pyran copolymer via the side chain of the drug. Cancer Treat. Reps. 1987, 71:367-373.
-
(1987)
Cancer Treat. Reps.
, vol.71
, pp. 367-373
-
-
Zunino, F.1
Pratesi, G.2
Pezzoni, G.3
-
125
-
-
0021713173
-
Targeting of daunorubicin by association with DNA or proteins: a review
-
Trouet A., Jolles G. Targeting of daunorubicin by association with DNA or proteins: a review. Sem. Oncol. 1984, 11:64-73.
-
(1984)
Sem. Oncol.
, vol.11
, pp. 64-73
-
-
Trouet, A.1
Jolles, G.2
-
126
-
-
0026694788
-
Passive tumour targeting of soluble macromolecules and drug conjugates
-
Seymour L.W. Passive tumour targeting of soluble macromolecules and drug conjugates. Crit. Rev. Therapeut. Drug Carr. Syst. 1992, 9:135-187.
-
(1992)
Crit. Rev. Therapeut. Drug Carr. Syst.
, vol.9
, pp. 135-187
-
-
Seymour, L.W.1
-
127
-
-
0024508158
-
Activity of N-(2-hydroxypropyl)methacrylamide copolymers containing daunomycin against a rat tumour model
-
Cassidy J., Duncan R., Morrison G.J., Strohalm J., et al. Activity of N-(2-hydroxypropyl)methacrylamide copolymers containing daunomycin against a rat tumour model. Biochem. Pharmacol. 1989, 38:875-880.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 875-880
-
-
Cassidy, J.1
Duncan, R.2
Morrison, G.J.3
Strohalm, J.4
-
128
-
-
0345606136
-
Preclinical evaluation of polymer-bound doxorubicin
-
Duncan R., Seymour L.W., O'Hare K.B., Flanagan P.A., et al. Preclinical evaluation of polymer-bound doxorubicin. J. Controlled Rel. 1992, 18:123-132.
-
(1992)
J. Controlled Rel.
, vol.18
, pp. 123-132
-
-
Duncan, R.1
Seymour, L.W.2
O'Hare, K.B.3
Flanagan, P.A.4
-
129
-
-
0028030559
-
Tumourtropism and anticancer afficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma
-
Seymour L.W., Ulbrich K., Steyger P.S., Brereton M., et al. Tumourtropism and anticancer afficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma. Br. J. Cancer 1994, 70:636-641.
-
(1994)
Br. J. Cancer
, vol.70
, pp. 636-641
-
-
Seymour, L.W.1
Ulbrich, K.2
Steyger, P.S.3
Brereton, M.4
-
130
-
-
0029039418
-
Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier
-
Seymour L.W., Miyamoto Y., Maeda H., Brereton M., et al. Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier. Eur. J. Cancer 1995, 31A:766-770.
-
(1995)
Eur. J. Cancer
, vol.31A
, pp. 766-770
-
-
Seymour, L.W.1
Miyamoto, Y.2
Maeda, H.3
Brereton, M.4
-
132
-
-
0041181628
-
HPMA copolymer-anticancer drug conjugates: design, activity and mechanism of action
-
Kopecek J., Kopeckova P., Minko T., Zheng-Rong L. HPMA copolymer-anticancer drug conjugates: design, activity and mechanism of action. Eur. J. Pharma. Biopharm. 2000, 50:61-81.
-
(2000)
Eur. J. Pharma. Biopharm.
, vol.50
, pp. 61-81
-
-
Kopecek, J.1
Kopeckova, P.2
Minko, T.3
Zheng-Rong, L.4
-
133
-
-
0026635281
-
Doxorubicia-loaded nanospheres bypass tumor cell multidrug resistance
-
Cuvier C., Roblot-Treupel L., Millot J.M., Lizard G., et al. Doxorubicia-loaded nanospheres bypass tumor cell multidrug resistance. Biochem. Pharmacol. 1992, 44:509-517.
-
(1992)
Biochem. Pharmacol.
, vol.44
, pp. 509-517
-
-
Cuvier, C.1
Roblot-Treupel, L.2
Millot, J.M.3
Lizard, G.4
-
134
-
-
0026770694
-
Increased accumulation of drugs in multidrug resistant cell induced by liposomes
-
Warren L., Jardilier J.C., Malarska A., Akeli M.G. Increased accumulation of drugs in multidrug resistant cell induced by liposomes. Cancer Res. 1992, 52:3241-3245.
-
(1992)
Cancer Res.
, vol.52
, pp. 3241-3245
-
-
Warren, L.1
Jardilier, J.C.2
Malarska, A.3
Akeli, M.G.4
-
135
-
-
0027816261
-
Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistance in a rat hepatoma
-
Ohkawa K., Hatano T., Yamada K., Joh K., et al. Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistance in a rat hepatoma. Cancer Res. 1993, 53:4238-4242.
-
(1993)
Cancer Res.
, vol.53
, pp. 4238-4242
-
-
Ohkawa, K.1
Hatano, T.2
Yamada, K.3
Joh, K.4
-
136
-
-
0033105569
-
A possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by antibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier
-
Stastny M., Strohalm J., Plocova D., Ulbrich K., Rihova B. A possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by antibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier. Eur. J. Cancer 1999, 35:459-466.
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 459-466
-
-
Stastny, M.1
Strohalm, J.2
Plocova, D.3
Ulbrich, K.4
Rihova, B.5
-
137
-
-
0345367901
-
HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in human ovarian carcinoma cell line
-
Minko T., Kopeckova P., Pozharov V., Kopecek J. HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in human ovarian carcinoma cell line. J. Controlled Rel. 1998, 54:223-233.
-
(1998)
J. Controlled Rel.
, vol.54
, pp. 223-233
-
-
Minko, T.1
Kopeckova, P.2
Pozharov, V.3
Kopecek, J.4
-
138
-
-
0034333734
-
Chronic exposure of human ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin e(6) does not induce P-glycoprotein-mediated multidrug resistance
-
Tijerina M., Fowers K.D., Kopeckova P., Kopecek J. Chronic exposure of human ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin e(6) does not induce P-glycoprotein-mediated multidrug resistance. Biomaterials 2000, 21:2203-2210.
-
(2000)
Biomaterials
, vol.21
, pp. 2203-2210
-
-
Tijerina, M.1
Fowers, K.D.2
Kopeckova, P.3
Kopecek, J.4
-
139
-
-
0036215202
-
Activation induced cell death: the controversial role of Fas and Fas ligand in immune privilege and tumour counterattack
-
Maher S., Toomey D., Condron C., Bouchier-Hayes D. Activation induced cell death: the controversial role of Fas and Fas ligand in immune privilege and tumour counterattack. Immunol. Cell Biol. 2002, 80:131-137.
-
(2002)
Immunol. Cell Biol.
, vol.80
, pp. 131-137
-
-
Maher, S.1
Toomey, D.2
Condron, C.3
Bouchier-Hayes, D.4
-
140
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell 1997, 88:355-365.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
141
-
-
0008796978
-
Dendritic cells prevent CD95-mediated T lymphocyte death through costimulatory signals
-
Daniel P.T., Scholz C., Westermann J., Dorken B., Pezzutto A. Dendritic cells prevent CD95-mediated T lymphocyte death through costimulatory signals. Gene Ther. Cancer 1998, 28:173-177.
-
(1998)
Gene Ther. Cancer
, vol.28
, pp. 173-177
-
-
Daniel, P.T.1
Scholz, C.2
Westermann, J.3
Dorken, B.4
Pezzutto, A.5
-
142
-
-
0034080750
-
Not so Fas: re-evaluating the mechanism of immune privilege and tumor escape
-
Restifo N. Not so Fas: re-evaluating the mechanism of immune privilege and tumor escape. Nat. Med. 2000, 6:493-495.
-
(2000)
Nat. Med.
, vol.6
, pp. 493-495
-
-
Restifo, N.1
-
143
-
-
0028670382
-
The role of APO-1-mediated apoptosis in the immune system
-
Krammer P.H., Dhein J., Walczak H., Behermann I., et al. The role of APO-1-mediated apoptosis in the immune system. Immunol. Rev. 1994, 142:175-191.
-
(1994)
Immunol. Rev.
, vol.142
, pp. 175-191
-
-
Krammer, P.H.1
Dhein, J.2
Walczak, H.3
Behermann, I.4
-
144
-
-
0033018370
-
The Fas counterattack: cancer as a site of immune privilege
-
O'Connell J., Bennett M.W., O'Sullivan G.C., Collins J.K., Shanahan F. The Fas counterattack: cancer as a site of immune privilege. Immunol. Today 1999, 20:46-52.
-
(1999)
Immunol. Today
, vol.20
, pp. 46-52
-
-
O'Connell, J.1
Bennett, M.W.2
O'Sullivan, G.C.3
Collins, J.K.4
Shanahan, F.5
-
145
-
-
0029808372
-
The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
-
O'Connell J., O'Sullivan G.C., Collins J.K., Shanahan F. The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand. J. Exp. Med. 1996, 184:1075-1082.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1075-1082
-
-
O'Connell, J.1
O'Sullivan, G.C.2
Collins, J.K.3
Shanahan, F.4
-
146
-
-
10544232277
-
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape
-
Hahne M., Rinoldi D., Schroter M., Romero P., et al. Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape. Science 1996, 274:1363-1366.
-
(1996)
Science
, vol.274
, pp. 1363-1366
-
-
Hahne, M.1
Rinoldi, D.2
Schroter, M.3
Romero, P.4
-
147
-
-
16144363507
-
Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells - a mechanism of immune evasion?
-
Strand S., Hofmann W.J., Hug H., Muller M., et al. Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells - a mechanism of immune evasion?. Nat. Med. 1996, 2:1361-1366.
-
(1996)
Nat. Med.
, vol.2
, pp. 1361-1366
-
-
Strand, S.1
Hofmann, W.J.2
Hug, H.3
Muller, M.4
-
148
-
-
0030933337
-
Human lung carcinomas express Fas ligand
-
Niehans G.A., Brunner T., Frizelle S.P., Liston J.C., et al. Human lung carcinomas express Fas ligand. Cancer Res. 1997, 57:1007-1012.
-
(1997)
Cancer Res.
, vol.57
, pp. 1007-1012
-
-
Niehans, G.A.1
Brunner, T.2
Frizelle, S.P.3
Liston, J.C.4
-
149
-
-
0032893304
-
Pancreatic cancer cells can evade immune surveillance via nonfunctional Fas(APO-1/CD95) receptors and aberrant expression of functional Fas ligand
-
Von Bernstorff W., Spanjaard R.A., Chan A.K., Lockhart D.C., et al. Pancreatic cancer cells can evade immune surveillance via nonfunctional Fas(APO-1/CD95) receptors and aberrant expression of functional Fas ligand. Surgery 1999, 125:73-84.
-
(1999)
Surgery
, vol.125
, pp. 73-84
-
-
Von Bernstorff, W.1
Spanjaard, R.A.2
Chan, A.K.3
Lockhart, D.C.4
-
150
-
-
0032103027
-
The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma
-
Bennett M.W., O'Connell J., O'Sullivan G.C., Brady C., et al. The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma. J. Immunol. 1998, 160:5669-5675.
-
(1998)
J. Immunol.
, vol.160
, pp. 5669-5675
-
-
Bennett, M.W.1
O'Connell, J.2
O'Sullivan, G.C.3
Brady, C.4
-
151
-
-
0031740779
-
Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloprotease
-
Mitsiades N., Poulaki V., Kotoula V., Leone A., Tsokos M. Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloprotease. Am. J. Pathol. 1998, 153:1947-1956.
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 1947-1956
-
-
Mitsiades, N.1
Poulaki, V.2
Kotoula, V.3
Leone, A.4
Tsokos, M.5
-
152
-
-
0029935682
-
Involvement of the CD95 (Apo-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen C., Herr I., Krammer P.H., Debatin K.-M. Involvement of the CD95 (Apo-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat. Med. 1996, 2:574-577.
-
(1996)
Nat. Med.
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.-M.4
-
153
-
-
0031570098
-
Role of Fas ligand (CD95L) in immune escape: the tumor cell strikes back - commentary
-
Walker P.R., Saas P., Dietrich P.-Y. Role of Fas ligand (CD95L) in immune escape: the tumor cell strikes back - commentary. J. Immunol. 1997, 15:4521-4524.
-
(1997)
J. Immunol.
, vol.15
, pp. 4521-4524
-
-
Walker, P.R.1
Saas, P.2
Dietrich, P.-Y.3
-
154
-
-
0032742205
-
Cytotoxic drugs and the CD95 pathways
-
Friesen C., Fulda S., Debatin K.-M. Cytotoxic drugs and the CD95 pathways. Leukemia 1999, 13:1854-1858.
-
(1999)
Leukemia
, vol.13
, pp. 1854-1858
-
-
Friesen, C.1
Fulda, S.2
Debatin, K.-M.3
-
155
-
-
2142809327
-
Immunoprotective therapy with targeted anticancer drugs
-
Rihova B., Strohalm J., Hoste K., Jelinkova M., et al. Immunoprotective therapy with targeted anticancer drugs. Macromol. Symp. 2001, 172:21-28.
-
(2001)
Macromol. Symp.
, vol.172
, pp. 21-28
-
-
Rihova, B.1
Strohalm, J.2
Hoste, K.3
Jelinkova, M.4
-
156
-
-
0001481221
-
Macromolecular prodrugs of 5-aminosalicylic acid, 1. Azo-conjugates
-
Callant D., Schacht E. Macromolecular prodrugs of 5-aminosalicylic acid, 1. Azo-conjugates. Makromol. Chem. 1990, 191:529-536.
-
(1990)
Makromol. Chem.
, vol.191
, pp. 529-536
-
-
Callant, D.1
Schacht, E.2
-
157
-
-
0029971849
-
Polymers for colon specific drug delivery
-
Schacht E., Gevaert A., Kenawy E.R., Molly K., Verstraete W., et al. Polymers for colon specific drug delivery. J. Controlled Rel. 1996, 39:327-338.
-
(1996)
J. Controlled Rel.
, vol.39
, pp. 327-338
-
-
Schacht, E.1
Gevaert, A.2
Kenawy, E.R.3
Molly, K.4
Verstraete, W.5
-
158
-
-
0001504460
-
Release of 5-aminosalicylic acid from bioadhesive N-(2-hydroxypropyl)methacrylamide copolymers by azoreductases in vitro
-
Kopeckova P., Kopecek J. Release of 5-aminosalicylic acid from bioadhesive N-(2-hydroxypropyl)methacrylamide copolymers by azoreductases in vitro. Makromol. Chem. 1990, 191:2037-2045.
-
(1990)
Makromol. Chem.
, vol.191
, pp. 2037-2045
-
-
Kopeckova, P.1
Kopecek, J.2
|