Histone deacetylase 3 and 4 complex stimulates the transcriptional activity of the mineralocorticoid receptor

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Lee, Hae Ahm ^a   Song, Min Ji ^a   Seok, Young Mi ^a,b   Kang, Seol Hee ^a   Kim, Sang Yeob ^c,d   Kim, Inkyeom ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Korea Promotion Institute for Traditional Medicine Industry   (South Korea)

^c Asan Medical Center   (South Korea)

^d University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 4; MINERALOCORTICOID RECEPTOR; PHOSPHOPROTEIN PHOSPHATASE; RNA POLYMERASE II; CALYCULIN A; HDAC4 PROTEIN, HUMAN; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; OXAZOLE DERIVATIVE; REPRESSOR PROTEIN; SMALL INTERFERING RNA;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEAR LOCALIZATION SIGNAL; PROTEIN ACETYLATION; PROTEIN DEPLETION; PROTEIN DNA BINDING; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ACETYLATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PROMOTER REGION;

ACETYLATION; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; OXAZOLES; PHOSPHOPROTEIN PHOSPHATASES; PROMOTER REGIONS, GENETIC; RECEPTORS, MINERALOCORTICOID; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC;

EID: 84942886751     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0136801     Document Type: Article

References (33)

1. Lee HA, Lee DY, Cho HM, Kim SY, Iwasaki Y, Kim IK. Histone deacetylase inhibition attenuates transcriptional activity of mineralocorticoid receptor through its acetylation and prevents development of hypertension. Circ Res. 2013;112(7):1004-12. Epub 2013/02/21. CIRCRESAHA.113.301071 [pii] doi: 10.1161/CIRCRESAHA.113.301071 PMID: 23421989.
2. Di Marcotullio L, Canettieri G, Infante P, Greco A, Gulino A. Protected from the inside: endogenous histone deacetylase inhibitors and the road to cancer. Biochim Biophys Acta. 2011;1815(2):241-52. Epub 2011/02/01. S0304-419X (11) 00003-5 [pii] doi: 10.1016/j.bbcan. 2011.01.002 PMID: 21277938.
3. Morris MJ, Monteggia LM. Unique functional roles for class I and class II histone deacetylases in central nervous system development and function. Int J Dev Neurosci. 2013;31(6):370-81. Epub 2013/03/08. S0736-5748 (13) 00032-4 [pii] doi: 10.1016/j.ijdevneu.2013.02.005 PMID: 23466417; PubMed Central PMCID: PMC3726026.
4. Lahm A, Paolini C, Pallaoro M, Nardi MC, Jones P, Neddermann P, et al. Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases. Proc Natl Acad Sci U S A. 2007;104(44):17335-40. Epub 2007/10/25. 0706487104 [pii] doi: 10.1073/pnas.0706487104 PMID: 17956988; PubMed Central PMCID: PMC2077257.
5. Schuetz A, Min J, Allali-Hassani A, Schapira M, Shuen M, Loppnau P, et al. Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. J Biol Chem. 2008;283(17):11355-63. Epub 2008/02/21. M707362200 [pii] doi: 10.1074/jbc. M707362200 PMID: 18285338; PubMed Central PMCID: PMC2431080.
6. Mielcarek M, Seredenina T, Stokes MP, Osborne GF, Landles C, Inuabasi L, et al. HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo. PloS one. 2013;8(11):e80849. doi: 10. 1371/journal.pone.0080849 PMID: 24278330; PubMed Central PMCID: PMC3838388.
7. Fischle W, Dequiedt F, Hendzel MJ, Guenther MG, Lazar MA, Voelter W, et al. Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/NCoR. Mol Cell. 2002;9(1):45-57. Epub 2002/01/24. S1097276501004294 [pii]. PMID: 11804585.
8. Parra M, Verdin E. Regulatory signal transduction pathways for class IIa histone deacetylases. Curr Opin Pharmacol. 2010;10(4):454-60. doi: 10.1016/j.coph.2010.04.004 PMID: 20447866.
9. Paroni G, Cernotta N, Dello Russo C, Gallinari P, Pallaoro M, Foti C, et al. PP2A regulates HDAC4 nuclear import. Mol Biol Cell. 2008;19(2):655-67. Epub 2007/11/30. E07-06-0623 [pii] doi: 10.1091/mbc. E07-06-0623 PMID: 18045992; PubMed Central PMCID: PMC2230598.
10. Berdeaux R, Goebel N, Banaszynski L, Takemori H, Wandless T, Shelton GD, et al. SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes. Nature medicine. 2007;13(5):597-603. doi: 10.1038/nm1573 PMID: 17468767.
11. Grozinger CM, Schreiber SL. Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization. Proc Natl Acad Sci U S A. 2000;97(14):7835-40. Epub 2000/06/28. doi: 10.1073/pnas.140199597 140199597 [pii]. PMID: 10869435; PubMed Central PMCID: PMC16631.
12. Walkinshaw DR, Weist R, Xiao L, Yan K, Kim GW, Yang XJ. Dephosphorylation at a conserved SP motif governs cAMP sensitivity and nuclear localization of class IIa histone deacetylases. J Biol Chem. 2013;288(8):5591-605. Epub 2013/01/09. M112.445668 [pii] doi: 10.1074/jbc. M112.445668 PMID: 23297420; PubMed Central PMCID: PMC3581380.
13. Walkinshaw DR, Weist R, Kim GW, You L, Xiao L, Nie J, et al. The tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases. J Biol Chem. 2013;288(13):9345-62. Epub 2013/02/09. M113.456996 [pii] doi: 10.1074/jbc. M113.456996 PMID: 23393134; PubMed Central PMCID: PMC3611005.
14. Dodge-Kafka KL, Bauman A, Mayer N, Henson E, Heredia L, Ahn J, et al. cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3. J Biol Chem. 2010;285(15):11078-86. doi: 10.1074/jbc. M109.034868 PMID: 20106966; PubMed Central PMCID: PMC2856983.
15. Gregoire S, Xiao L, Nie J, Zhang X, Xu M, Li J, et al. Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2. Mol Cell Biol. 2007;27(4):1280-95. Epub 2006/12/13. MCB.00882-06 [pii] doi: 10.1128/MCB.00882-06 PMID: 17158926; PubMed Central PMCID: PMC1800729.
16. Yang XJ, Gregoire S. Class II histone deacetylases: from sequence to function, regulation, and clinical implication. Mol Cell Biol. 2005;25(8):2873-84. Epub 2005/03/31. 25/8/2873 [pii] doi: 10.1128/MCB. 25.8.2873-2884.2005 PMID: 15798178; PubMed Central PMCID: PMC1069616.
17. Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, et al. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. 2011;145(4):607-21. Epub 2011/05/14. S0092-8674 (11) 00377-1 [pii] doi: 10.1016/j.cell.2011.03.043 PMID: 21565617; PubMed Central PMCID: PMC3117637.
18. Kadiyala V, Patrick NM, Mathieu W, Jaime-Frias R, Pookhao N, An L, et al. Class I lysine deacetylases facilitate glucocorticoid-induced transcription. J Biol Chem. 2013;288(40):28900-12. Epub 2013/08/16. M113.505115 [pii] doi: 10.1074/jbc. M113.505115 PMID: 23946490; PubMed Central PMCID: PMC3789985.
19. Lauffer BE, Mintzer R, Fong R, Mukund S, Tam C, Zilberleyb I, et al. Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability. J Biol Chem. 2013;288(37):26926-43. Epub 2013/07/31. M113.490706 [pii] doi: 10.1074/jbc. M113. 490706 PMID: 23897821; PubMed Central PMCID: PMC3772242.
20. Nader N, Chrousos GP, Kino T. Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications. FASEB journal: official publication of the Federation of American Societies for Experimental Biology.. 2009;23(5):1572-83. doi: 10.1096/fj.08-117697 PMID: 19141540; PubMed Central PMCID: PMC2669420.
21. Xie S, Ni J, Lee YF, Liu S, Li G, Shyr CR, et al. Increased acetylation in the DNA-binding domain of TR4 nuclear receptor by the coregulator ARA55 leads to suppression of TR4 transactivation. J Biol Chem. 2011;286(24):21129-36. Epub 2011/04/26. M110.208181 [pii] doi: 10.1074/jbc. M110.208181 PMID: 21515881; PubMed Central PMCID: PMC3122174.
22. Liu Y, Schneider MF. Opposing HDAC4 nuclear fluxes due to phosphorylation by beta-adrenergic activated protein kinase A or by activity or Epac activated CaMKII in skeletal muscle fibres. J Physiol. 2013;591(Pt 14):3605-23. Epub 2013/05/09. jphysiol.2013.256263 [pii] doi: 10.1113/jphysiol.2013. 256263 PMID: 23652597; PubMed Central PMCID: PMC3731617.
23. Du M, Perry RL, Nowacki NB, Gordon JW, Salma J, Zhao J, et al. Protein kinase A represses skeletal myogenesis by targeting myocyte enhancer factor 2D. Mol Cell Biol. 2008;28(9):2952-70. Epub 2008/02/27. MCB.00248-08 [pii] doi: 10.1128/MCB.00248-08 PMID: 18299387; PubMed Central PMCID: PMC2293079.
24. Kozhemyakina E, Cohen T, Yao TP, Lassar AB. Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway. Mol Cell Biol. 2009;29(21):5751-62. Epub 2009/08/26. MCB.00415-09 [pii] doi: 10.1128/MCB.00415-09 PMID: 19704004; PubMed Central PMCID: PMC2772746.
25. Ling S, Sun Q, Li Y, Zhang L, Zhang P, Wang X, et al. CKIP-1 inhibits cardiac hypertrophy by regulating class II histone deacetylase phosphorylation through recruiting PP2A. Circulation. 2012;126(25):3028-40. Epub 2012/11/16. CIRCULATIONAHA.112.102780 [pii] doi: 10.1161/CIRCULATIONAHA.112.102780 PMID: 23151343.
26. Gross DN, Van Den Heuvel AP, Birnbaum MJ. The role of FoxO in the regulation of metabolism. Oncogene. 2008;27(16):2320-36. Epub 2008/04/09. onc200825 [pii] doi: 10.1038/onc.2008.25 PMID: 18391974.
27. Viengchareun S, Le Menuet D, Martinerie L, Munier M, Pascual-Le Tallec L, Lombes M. The mineralocorticoid receptor: insights into its molecular and (patho) physiological biology. Nucl Recept Signal. 2007;5:e012. Epub 2008/01/05. doi: 10.1621/nrs.05012 PMID: 18174920; PubMed Central PMCID: PMC2121322.
28. Lastra G, Dhuper S, Johnson MS, Sowers JR. Salt, aldosterone, and insulin resistance: impact on the cardiovascular system. Nat Rev Cardiol. 2010;7(10):577-84. Epub 2010/08/11. nrcardio.2010.123 [pii] doi: 10.1038/nrcardio.2010.123 PMID: 20697411.
29. Christ M, Gunther A, Heck M, Schmidt BM, Falkenstein E, Wehling M. Aldosterone, not estradiol, is the physiological agonist for rapid increases in cAMP in vascular smooth muscle cells. Circulation. 1999;99(11):1485-91. Epub 1999/03/23. PMID: 10086974.
30. Sheader EA, Wargent ET, Ashton N, Balment RJ. Rapid stimulation of cyclic AMP production by aldosterone in rat inner medullary collecting ducts. J Endocrinol. 2002;175(2):343-7. Epub 2002/11/14. PMID: 12429032.
31. Spiegel S, Milstien S, Grant S. Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. Oncogene. 2012;31(5):537-51. Epub 2011/07/05. onc2011267 [pii] doi: 10.1038/onc.2011.267 PMID: 21725353; PubMed Central PMCID: PMC3356932.
32. Bertrand P. Inside HDAC with HDAC inhibitors. Eur J Med Chem. 2010;45(6):2095-116. Epub 2010/03/13. S0223-5234 (10) 00147-9 [pii] doi: 10.1016/j.ejmech.2010.02.030 PMID: 20223566.
33. Iyer A, Fairlie DP, Brown L. Lysine acetylation in obesity, diabetes and metabolic disease. Immunol Cell Biol. 2012;90(1):39-46. Epub 2011/11/16. icb201199 [pii] doi: 10.1038/icb.2011.99 PMID: 22083525.