Clopidogrel and aspirin versus aspirin alone for stroke prevention: A meta-analysis

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Tan, Shuai ^a   Xiao, Xiaojuan ^a   Ma, Hanyu ^a   Zhang, Zhaohui ^a   Chen, Jiangbo ^a   Ding, Lei ^a   Yu, Shenping ^a   Xu, Rulin ^a   Yang, Shiliang ^a   Huang, Xinyi ^a   Hong, Hua ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; TICLOPIDINE;

ARTICLE; BLEEDING; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; COMBINATION CHEMOTHERAPY; DRUG EFFECT; DRUG SAFETY; HUMAN; META ANALYSIS; MONOTHERAPY; MORTALITY; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK ASSESSMENT; SYSTEMATIC REVIEW; ANALOGS AND DERIVATIVES; CHEMICALLY INDUCED; COMPARATIVE STUDY; FEMALE; MALE; STROKE;

ASPIRIN; FEMALE; HEMORRHAGE; HUMANS; MALE; STROKE; TICLOPIDINE;

EID: 84942879733     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0135372     Document Type: Article

References (22)

1. Sacco RL, Shi T, Zamanillo MC, Kargman DE. Predictors of mortality and recurrence after hospitalized cerebral infarction in an urban community The Northern Manhattan Stroke Study. Neurology. 1994;44:626-626. PMID: 8164815
2. Sacco RL, Wolf PA, Kannel WB, McNamara PM. Survival and recurrence following stroke. The Framingham study. Stroke. 1982;13:290-295. PMID: 7080120
3. Petty GW, Brown RD Jr, Whisnant JP, Sicks JD, O'Fallon WM, Wiebers DO. Survival and recurrence after first cerebral infarction: a population-based study in Rochester, Minnesota, 1975 through 1989. Neurology. 1998;50:208-216. PMID: 9443482
4. Rothwell PM, Giles MF, Flossmann E, Lovelock CE, Redgrave JN, Warlow CP, et al. A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischaemic attack. Lancet. 2005;366:29-36. PMID: 15993230
5. Johnston SC, Gress DR, Browner WS, Sidney S. Short-term prognosis after emergency department diagnosis of TIA. JAMA. 2000;284:2901-2906. PMID: 11147987
6. Epstein FH, Boas EP. The prevalence of manifest atherosclerosis among randomly chosen Italian and Jewish garment workers a preliminary report. J Gerontol. 1955;10:331-337. PMID: 13242776
7. Hachinski V. World Stroke Day 2008 "Little Strokes, Big Trouble." Stroke. 2008;39:2407-2408. doi: 10.1161/STROKEAHA.108.531681 PMID: 18723419
8. Fischer U, Baumgartner A, Arnold M, Nedeltchev K, Gralla J, De Marchis GM, et al. What is a minor stroke? Stroke. 2010;41:661-666. doi: 10.1161/STROKEAHA.109.572883 PMID: 20185781
9. Röther J, Alberts MJ, Touzé E, Mas JL, Hill MD, Michel P, et al. Risk factor profile and management of cerebrovascular patients in the REACH Registry. Cerebrovasc Dis. 2008;25:366-374. doi: 10.1159/000120687 PMID: 18337635
10. Bamford J, Sandercock P, Dennis M, Burn J, Warlow C. Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet. 1991;337:1521-1526. PMID: 1675378
11. Uyttenboogaart M, Stewart RE, Vroomen PC, De Keyser J, Luijckx GJ. Optimizing cutoff scores for the Barthel index and the modified Rankin scale for defining outcome in acute stroke trials. Stroke. 2005;36:1984-1987. PMID: 16081854
12. Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, et al. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet. 2004;364:331-337. PMID: 15276392
13. Lee M, Wu YL, Saver JL, Lee HC, Lee JD, Chang KC, et al. Is clopidogrel better than aspirin following breakthrough strokes while on aspirin? A retrospective cohort study. Bmj Open, 2014;4:e006672-e006672. doi: 10.1136/bmjopen-2014-006672 PMID: 25468508
14. Wanyong Yang, Anding Xu, Feng Qi, Yan Huang, Ke Yu, Youjia Li, et al. A Pilot Trial of Clopidogrel of Loading Dosage to Treat non Cardioembolic Acute Ischemic Stroke/Transient Ischemic Attack in China (CLASS-CHINA Pilot). Chinese Journal of Nervous and Mental Diseases. 2008;11:658-662
15. Schünemann HJ, Oxman AD, Vist GE, Higgins JPT, Deeks JJ, Glasziou P, et al. Chapter 12: Interpreting results and drawing conclusions. In: Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews of interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available: www.cochranehandbook.org.
16. Kennedy J, Hill MD, Ryckborst KJ, Eliasziw M, Demchuk AM, Buchan AM, et al. Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial. Lancet Neurol. 2007;6:961-969. PMID: 17931979
17. Wong KS, Chen C, Fu J, Chang HM, Suwanwela NC, Huang YN, et al. Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trial. Lancet Neurol. 2010;9:489-497. doi: 10.1016/S1474-4422 (10) 70060-0 PMID: 20335070
18. Wang Y, Wang Y, Zhao X, Liu L, Wang D, Wang C, et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med. 2013;369:11-19. doi: 10.1056/NEJMoa1215340 PMID: 23803136
19. SPS3 Investigators, Benavente OR, Hart RG, McClure LA, Szychowski JM, Coffey CS, et al. Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. N Engl J Med. 2012;367:817-825. doi: 10.1056/NEJMoa1204133 PMID: 22931315
20. Bhatt DL, Fox KA, Hacke W, Berger PB, Black HR, Boden WE, et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med. 2006;354:1706-1717. PMID: 16531616
21. Kernan WN, Ovbiagele B, Black HR, Bravata DM, Chimowitz MI, Ezekowitz MD, et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014;45:2160-2236. doi: 10.1161/STR.0000000000000024 PMID: 24788967
22. Furie KL, Kasner SE, Adams RJ, Albers GW, Bush RL, Fagan SC, et al. Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:227-276. doi: 10. 1161/STR.0b013e3181f7d043 PMID: 20966421