메뉴 건너뛰기




Volumn 31, Issue 8, 2015, Pages 635-638

The adjuvant effect of metformin and N -acetylcysteine to clomiphene citrate in induction of ovulation in patients with Polycystic Ovary Syndrome

Author keywords

Clomiphene citrate; induction of ovulation; metformin; N acetylcysteine; Polycystic Ovary Syndrome

Indexed keywords

ACETYLCYSTEINE; CLOMIFENE CITRATE; ESTRADIOL; FOLLITROPIN; LUTEINIZING HORMONE; METFORMIN; PROLACTIN; CLOMIFENE; FERTILITY PROMOTING AGENT;

EID: 84942833984     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513590.2015.1037269     Document Type: Article
Times cited : (24)

References (14)
  • 1
    • 77951697875 scopus 로고    scopus 로고
    • Definition, diagnosis, and epidemiology of the polycystic ovary syndrome
    • Azziz R., ed. New York (NY): Springer
    • Azziz R. Definition, diagnosis, and epidemiology of the polycystic ovary syndrome. In: Azziz R., ed. The polycystic ovary syndrome: current concepts on pathogenesis and clinical care. New York (NY): Springer, 2007: ch 1: 1-15
    • (2007) The Polycystic Ovary Syndrome: Current Concepts on Pathogenesis and Clinical Care , pp. 1-15
    • Azziz, R.1
  • 2
    • 79953069240 scopus 로고    scopus 로고
    • Polycystic ovary syndrome: Etiology, pathogenesis and diagnosis
    • Goodarzi MO, Dumesic DA, Chazenbalk G, et al. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol 2011; 7: 219-31
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 219-231
    • Goodarzi, M.O.1    Dumesic, D.A.2    Chazenbalk, G.3
  • 3
    • 84894456925 scopus 로고    scopus 로고
    • Efficacy of combined metformin-clomiphene citrate in comparison with clomiphene citrate alone in infertile women with polycystic ovarian syndrome (PCOS)
    • Ayaz A, Alwan Y, Farooq MU. Efficacy of combined metformin-clomiphene citrate in comparison with clomiphene citrate alone in infertile women with polycystic ovarian syndrome (PCOS). J Med Life 2013; 6: 199-201
    • (2013) J Med Life , vol.6 , pp. 199-201
    • Ayaz, A.1    Alwan, Y.2    Farooq, M.U.3
  • 4
    • 0032565971 scopus 로고    scopus 로고
    • Effects of metformin on spontaneous and clomiphene-induced ovulation in the P.C.O.S
    • Nestler JE, Jakubowicz DJ, Evans WS, et al. Effects of metformin on spontaneous and clomiphene-induced ovulation in the P.C.O.S. N Engl J Med 1998; 338: 1876-80
    • (1998) N Engl J Med , vol.338 , pp. 1876-1880
    • Nestler, J.E.1    Jakubowicz, D.J.2    Evans, W.S.3
  • 5
    • 0037414415 scopus 로고    scopus 로고
    • N-acetyl cysteine protects against injury in a rat model of focal cerebral ischemia
    • Sekhon B, Sekhon C, Khan M, et al. N-acetyl cysteine protects against injury in a rat model of focal cerebral ischemia. Brain Res 2003; 971: 1-8
    • (2003) Brain Res , vol.971 , pp. 1-8
    • Sekhon, B.1    Sekhon, C.2    Khan, M.3
  • 6
    • 0038697896 scopus 로고    scopus 로고
    • N-acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in vitro
    • Lappas M, Permezel M, Rice GE. N-acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in vitro. J Clin Endocrinol Metab 2003; 88: 1723-9
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1723-1729
    • Lappas, M.1    Permezel, M.2    Rice, G.E.3
  • 7
    • 0346186090 scopus 로고    scopus 로고
    • Center of reproductive medicine, erasmus medical center, 3015 GD Rotterdam, Netherlands
    • The Rotterdam ESHRE/ASRA-Sponsored PCOS Consensus Workshop Group: Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
    • The Rotterdam ESHRE/ASRA-Sponsored PCOS Consensus Workshop Group: Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Bart C.J.M. Fauser, Center of Reproductive Medicine, Erasmus Medical Center, 3015 GD Rotterdam, Netherlands. Hum Reprod 2004;19:41-7
    • (2004) Hum Reprod , vol.19 , pp. 41-47
    • Fauser, B.C.J.M.1
  • 8
    • 33846961466 scopus 로고    scopus 로고
    • N-acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: A cross-over trial
    • Badawy A, State O, Abdelgawad S. N-acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: a cross-over trial. Acta Obstet Gynecol Scand 2007; 86: 218-22
    • (2007) Acta Obstet Gynecol Scand , vol.86 , pp. 218-222
    • Badawy, A.1    State, O.2    Abdelgawad, S.3
  • 9
    • 0031023058 scopus 로고    scopus 로고
    • Teratogenic effect of diabetic serum is prevented by supplementation of superoxide dismutase and N-acetyl cysteine in rat embryo culture
    • Wentzel P, Thunberg L, Eriksson UJ. Teratogenic effect of diabetic serum is prevented by supplementation of superoxide dismutase and N-acetyl cysteine in rat embryo culture. Diabetologia 1997; 40: 7-14
    • (1997) Diabetologia , vol.40 , pp. 7-14
    • Wentzel, P.1    Thunberg, L.2    Eriksson, U.J.3
  • 10
    • 23044513823 scopus 로고    scopus 로고
    • Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome
    • Palomba S, Orio F Jr, Falbo A, et al. Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome. J Clin Endoc Metab 2005; 90: 4068-74
    • (2005) J Clin Endoc Metab , vol.90 , pp. 4068-4074
    • Palomba, S.1    Orio, F.2    Falbo, A.3
  • 11
    • 0034458234 scopus 로고    scopus 로고
    • Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: A randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation
    • Moghetti P, Castello R, Negri C, et al. Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation. J Clin Endocrinol Metab 2000; 85: 139-46
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 139-146
    • Moghetti, P.1    Castello, R.2    Negri, C.3
  • 12
    • 84975849722 scopus 로고    scopus 로고
    • N-acetylcysteine as an adjuvant to clomiphene citrate for successful induction of ovulation in infertile patients with polycystic ovary syndrome
    • Saghar S, Azadeh AS, Nasrin S, et al. N-acetylcysteine as an adjuvant to clomiphene citrate for successful induction of ovulation in infertile patients with polycystic ovary syndrome. J Obstet Gynaecol Res 2012; 38: 1182-6
    • (2012) J Obstet Gynaecol Res , vol.38 , pp. 1182-1186
    • Saghar, S.1    Azadeh, A.S.2    Nasrin, S.3
  • 13
    • 13544250688 scopus 로고    scopus 로고
    • N-acetyl-cysteine is a novel adjuvant to clomiphene citrate in clomiphene citrate resistant patients with polycystic ovary syndrome
    • Rizk AY, Bedaiwy MA, Al-Inany HG. N-acetyl-cysteine is a novel adjuvant to clomiphene citrate in clomiphene citrate resistant patients with polycystic ovary syndrome. Fertil Steril 2005; 83: 367-70
    • (2005) Fertil Steril , vol.83 , pp. 367-370
    • Rizk, A.Y.1    Bedaiwy, M.A.2    Al-Inany, H.G.3
  • 14
    • 84942630906 scopus 로고    scopus 로고
    • N-acetylcysteine for polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled clinical trials
    • Thakker D, Raval A, Patel I, et al. N-acetylcysteine for polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled clinical trials. Obstet Gynecol Int 2015; 2015: 817849. doi: 10.1155/2015/817849
    • (2015) Obstet Gynecol Int , vol.2015 , pp. 817849
    • Thakker, D.1    Raval, A.2    Patel, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.